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Diagnosis and Treatment of Obstetrics and Gynecology Cancers

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Obstetrics & Gynecology".

Deadline for manuscript submissions: 31 January 2026 | Viewed by 483

Special Issue Editor

Special Issue Information

Dear Colleagues,

This Special Issue explores the evolving challenges in the diagnosis and management of gynecological malignancies and pregnancy-related cancers. In the area of gynecological oncology, we highlight the latest advances in multimodal treatment strategies for a variety of gynecological tumors, including cervical cancer, ovarian cancer, and endometrial cancer, including liquid biopsies for early detection, sentinel lymph node mapping, fertility-sparing surgical techniques, and PARP inhibitor therapy for BRCA-mutated tumors. The obstetrics section explores the complexity of pregnancy-associated breast cancer, gestational trophoblastic tumors, and cervical cancer diagnosed during pregnancy, emphasizing multidisciplinary decision-making to optimize maternal and fetal outcomes.

This Special Issue also explores emerging topics such as immunotherapy for mismatch repair-deficient endometrial cancer, AI-assisted imaging interpretation, and survivorship care. This Special Issue brings together contributions from experts to provide clinicians with practical insights into gynecologic oncology in the field of women's health.

Dr. Gaspare Cucinella
Guest Editor

Manuscript Submission Information

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Keywords

  • gynecological cancers
  • endometrial cancer
  • ovarian cancer
  • cervical cancer
  • vulvar cancer
  • vaginal cancer
  • breast cancer
  • surgery
  • radio-therapy
  • systemic treatment
  • immunotherapy
  • sentinel lymph node biopsy
  • minimally invasive surgery
  • fertility preservation
  • gestational trophoblastic disease

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Published Papers (1 paper)

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Review

13 pages, 522 KiB  
Review
Uterine Fibroids and Their Association with Acute and Chronic Venous Thromboembolic Disease—An Expert Review of the Literature
by Munaza Afaq, Brooke Alexa Zlotshewer, Estefania Oliveros, Sarah Gabrielle Bauman, Anjali Vaidya, Vladimir Lakhter, Paul Forfia, Ahmed S. Sadek, Enrique Hernandez and Riyaz Bashir
J. Clin. Med. 2025, 14(12), 4065; https://doi.org/10.3390/jcm14124065 - 9 Jun 2025
Viewed by 418
Abstract
Venous thromboembolism is significantly affected by hormonal and reproductive factors that pose unique challenges in women. Among various risk factors, the role of uterine fibroids, which are the most common benign tumors in women, is not well understood. The relationship between venous thromboembolism [...] Read more.
Venous thromboembolism is significantly affected by hormonal and reproductive factors that pose unique challenges in women. Among various risk factors, the role of uterine fibroids, which are the most common benign tumors in women, is not well understood. The relationship between venous thromboembolism and fibroids is mainly attributed to the physical compression caused by large fibroids on pelvic veins, particularly the iliac veins, leading to venous stasis and thrombosis. This review explores the prevalence, pathogenesis, risk factors, possible racial influences, and management strategies of venous thromboembolism associated with fibroids. It highlights the need for better awareness, considering the asymptomatic nature of many fibroids and their potential to lead to serious thromboembolic complications. There is a clear need for screening methods, detailed guidelines, and treatments to prevent such complications and improve women’s health care. Full article
(This article belongs to the Special Issue Diagnosis and Treatment of Obstetrics and Gynecology Cancers)
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