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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Hepatobiliary and Pancreatic (HPB) Surgery: Current Status and Future Perspectives

edited by Andrea Benedetti Cacciaguerra and Paolo Vincenzi

submission deadline 25 Sep 2026 | 4 articles | Viewed by 7181 | Submission Open

Keywords: hepatobiliary and pancreatic surgery; laparoscopic surgery; robot-assisted surgery; artificial intelligence; augmented reality; indocyanine green; liver tumors; pancreatic tumors

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Recent Advances in Prenatal Diagnosis and Maternal Fetal Medicine

edited by

Anca Angela Simionescu

and

Ştefania Tudorache

submission deadline 25 Sep 2026 | 2 articles | Viewed by 6939 | Submission Open

Keywords: prenatal; obstetrics; fetal abnormalities; intrauterine treatments; genetic disorders; pregnancy

(This special issue belongs to the Section Obstetrics & Gynecology)

Multiple Sclerosis and Demyelinating Diseases: Diagnosis, Treatment and Prognosis

edited by Alberto Gajofatto

submission deadline 25 Sep 2026 | 3 articles | Viewed by 6789 | Submission Open

Keywords: multiple sclerosis; neuromyelitis optica; MOG-antibody disease; diagnosis; prognosis; treatment

(This special issue belongs to the Section Clinical Neurology)

Pregnancy and Delivery Complications: Bridging Research and Clinical Practice

edited by

Maria Patricia Roman

, Andrei Mihai Malutan and Răzvan Ciortea

submission deadline 25 Sep 2026 | 5 articles | Viewed by 5870 | Submission Open

Keywords: maternal–fetal medicine; obstetric complications; perinatal health; pelvic floor disorders; childbirth perineal trauma; risk stratification; patient-reported outcomes; patient-reported outcome measures

(This special issue belongs to the Section Obstetrics & Gynecology)

Advances in Schizophrenia and Related Psychotic Disorders

edited by Giovanni Camardese and Michele Ribolsi

submission deadline 25 Sep 2026 | 4 articles | Viewed by 5477 | Submission Open

Keywords: psychosis; schizophrenia; severe mental illness; psychopharmacology; negative symptoms; antipsychotics

(This special issue belongs to the Section Mental Health)

Novel Developments in Dental and Oral Surgery

edited by

Antonio Rapani

Teresa Lombardi

and

Federico Berton

submission deadline 25 Sep 2026 | 4 articles | Viewed by 5324 | Submission Open

Keywords: guided bone regeneration; dental implant osseointegration; laser dentistry; maxillofacial reconstruction; sinus lift techniques

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

New Insights into Acne Vulgaris Treatment and Management Strategies

edited by Jo Linda Maria Sinagra

submission deadline 25 Sep 2026 | 2 articles | Viewed by 5093 | Submission Open

Keywords: acne; hormonal treatments; isotretinoin; laser therapy; antibiotic

(This special issue belongs to the Section Dermatology)

Periodontitis and Systemic Health: Exploring the Oral-Systemic Connection

edited by

Yiorgos Bobetsis

and Phoebus Madianos

submission deadline 25 Sep 2026 | 3 articles | Viewed by 5051 | Submission Open

Keywords: periodontal disease; systemic diseases; cardiovascular disease; diabetes mellitus; adverse pregnancy outcomes; respiratory disease; neurodegenerative disorders; obesity; respiratory diseases; chronic kidney disease

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Advances in Treatment and Prognosis for Acute Type A and Type B Aortic Dissections

edited by

Katsuhiko Oda

submission deadline 25 Sep 2026 | 4 articles | Viewed by 4703 | Submission Open

Keywords: acute aortic dissection; stent graft; false lumen expansion; thoracic endovascular aortic repair; initial surgery for Type A acute aortic dissection; frozen elephant trunk

(This special issue belongs to the Section Cardiovascular Medicine)

Meibomian Gland Dysfunction and Dry Eye Diseases

edited by

Reiko Arita

and

KyoungYul Seo

submission deadline 25 Sep 2026 | 6 articles | Viewed by 4159 | Submission Open

Keywords: meibomian gland; meibomian gland dysfunction; dry eye disease; ocular surface; meibography; lipid layer; tear film; inflammation; therapy; diagnosis; epidemiology; clinical study

(This special issue belongs to the Section Ophthalmology)

New Clinical Advances in Sudden Cardiac Arrest and Ventricular Arrhythmias: 2nd Edition

edited by

Simone Savastano

submission deadline 25 Sep 2026 | 2 articles | Viewed by 2978 | Submission Open

Keywords: cardiac arrest; defibrillation; ventricular tachycardia; ventricular fibrillation; catheter ablation; non-invasive ablation; neuromodulation; stellate ganglion block

(This special issue belongs to the Section Cardiology)

Diagnosis and Treatment for Hearing Loss: Expert Views

edited by

Robert A. Saadi

and John L. Dornhoffer

submission deadline 25 Sep 2026 | 2 articles | Viewed by 2877 | Submission Open

Keywords: hearing loss; cochlear implants; hearing aid technology; regenerative medicine; diagnostic audiology

(This special issue belongs to the Section Otolaryngology)

Current Advances and Future Perspectives of Sepsis and Septic Shock

edited by Filippo Mearelli and Gianni Biolo

submission deadline 25 Sep 2026 | 2 articles | Viewed by 2516 | Submission Open

Keywords: sepsis; epidemiology; biomarkers; diagnosis; predictive models; prognostication

(This special issue belongs to the Section Emergency Medicine)

Deep Vein Thrombosis and Pulmonary Embolism: Current Clinical Treatment and Management

edited by Windsor Ting

submission deadline 25 Sep 2026 | 1 articles | Viewed by 2157 | Submission Open

Keywords: deep vein thrombosis; pulmonary embolus; vein stenosis. iliac vein stenosis; May-Thurner syndrome; thoracic outlet syndrome; renal vein stenosis; nutcracker syndrome

(This special issue belongs to the Section Vascular Medicine)

Latest Advances in Ocular Surface Diseases

edited by Barbara Burgos-Blasco

submission deadline 25 Sep 2026 | 2 articles | Viewed by 2098 | Submission Open

Keywords: cornea; keratitis; ocular surface disease; dry eye; corneal ulcer; keratoplasty; conjunctival disease

(This special issue belongs to the Section Ophthalmology)

Latest Advances in Minimally Invasive Spine Surgery

edited by Fabian Sommer and

Roger Härtl

submission deadline 25 Sep 2026 | 2 articles | Viewed by 1927 | Submission Open

Keywords: minimally invasive spine surgery (MISS); advances in spine surgery; future directions of MISS; navigation and orientation; intramedullary/extramedullary tumor resections; emerging technologies in MISS (robotics, augmented reality, artificial intelligence, etc.); degenerative spine; patient safety in MISS

(This special issue belongs to the Section Clinical Neurology)

Idiopathic Thrombocytopenic Purpura (ITP) and Thrombotic Thrombocytopenic Purpura (TTP): Pathophysiology, Clinical Practice and Future Developments

edited by María Eva Mingot Castellano

submission deadline 25 Sep 2026 | 2 articles | Viewed by 1659 | Submission Open

Keywords: ITP; TTP; thrombocytopenia; autoimmune; bleeding; thrombosis; caplacizumab; steroids; plasma exchange; infections; thrombopoetin; thrombopoetin analogs; immunosuppressive; immunomodulation; quality of life; fatigue

(This special issue belongs to the Section Hematology)

Corneal Surgery: From Innovation to Clinical Practice

edited by Joanna Wasielica-Poslednik

submission deadline 25 Sep 2026 | 1 articles | Viewed by 1534 | Submission Open

Keywords: keratoplasty; penetrating keratoplasty; DMEK; eye banking; corneal surgery

(This special issue belongs to the Section Ophthalmology)

Emergency Surgery: Recent Advances and Practical Strategies

edited by Avi Benov

submission deadline 25 Sep 2026 | 2 articles | Viewed by 1406 | Submission Open

Keywords: emergency surgery; acute care surgery; trauma; prehospital care; early decision-making; clinical outcomes; risk stratification; real-world evidence; registries

(This special issue belongs to the Section Emergency Medicine)

Tendon and Ligament Injury and Current Strategies for Tendon and Ligament Regeneration

edited by Andrej Čretnik, Bore Bakota and Dejan Blažević

submission deadline 25 Sep 2026 | 1 articles | Viewed by 1143 | Submission Open

Keywords: tendons; ligaments; injuries; tendinopathies; minimally invasive surgery; functional treatment; tissue engineering; novelties

(This special issue belongs to the Section Orthopedics)

Clinical Advances in General and Regional Anesthesia

edited by Luciano Frassanito

submission deadline 25 Sep 2026 | 1 articles | Viewed by 1117 | Submission Open

Keywords: oncoanesthesia; perinatal anesthesia; ventilatory support; hemodynamic monitoring; regional anesthesia

(This special issue belongs to the Section Anesthesiology)

Coronary Intervention: Current Strategies and Future Directions

edited by

Jong-Hwa Ahn

submission deadline 25 Sep 2026 | 2 articles | Viewed by 1110 | Submission Open

Keywords: coronary intervention; percutaneous coronary intervention; complex PCI; intravascular imaging; coronary physiology; antiplatelet therapy; cardiovascular outcomes

(This special issue belongs to the Section Cardiovascular Medicine)

Gastrointestinal Surgery and Pain Management: Contemporary Advances and Clinical Insights

edited by

Dimitrios Giannis

submission deadline 25 Sep 2026 | 1 articles | Viewed by 737 | Submission Open

Keywords: gastrointestinal surgery; postoperative pain; chronic pain; acute pain; perioperative care; pain management; multimodal analgesia; enhanced recovery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Ocular Microcirculation and Clinical Outcomes in Ophthalmic Diseases

edited by Robert Rejdak and

Małgorzata Latalska

submission deadline 25 Sep 2026 | 1 articles | Viewed by 673 | Submission Open

Keywords: ocular microcirculation; clinical outcomes; diabetic retinopathy; glaucoma; optic nerve diseases; ocular blood flow; ophthalmic diseases; retinal disorders; imaging techniques; hemodynamics

(This special issue belongs to the Section Ophthalmology)

Myeloid-Derived Suppressor and Innate Immune Cells in Hematologic, Malignant and Chronic Diseases

edited by

Helen A. Papadaki

submission deadline 25 Sep 2026 | Viewed by 474 | Submission Open

Keywords: myeloid-derived suppressor cells (MDSCs); macrophages; monocytes; eosinophils; neutrophils; malignancy; cancer; autoimmunity; infection; chronic inflammation; therapeutic target; biomarker; precision medicine; molecular pathways; bone marrow microenvironment

(This special issue belongs to the Section Hematology)

Advances in the Diagnosis and Management of Sarcoidosis

edited by

Carlos Feijoo-Massó

, Pilar Brito-Zerón and Miriam Akasbi Montalvo

submission deadline 25 Sep 2026 | Viewed by 368 | Submission Open

Keywords: sarcoidosis; diagnosis; biomarkers; imaging; immunopathogenesis; biologic therapy; prognosis; interstitial lung disease

(This special issue belongs to the Section Immunology & Rheumatology)

From Heart to Brain: Interdisciplinary Perspectives on Cerebral Infarction

edited by

Laurent Suissa

and Jean-Claude Deharo

submission deadline 25 Sep 2026 | Viewed by 362 | Submission Open

Keywords: ischemic stroke; cardioembolic stroke; atrial fibrillation; heart–brain axis; neurocardiology; post-stroke cardiac dysfunction; stroke prevention; cerebral infarction; cardiac monitoring in stroke; secondary stroke prevention

(This special issue belongs to the Section Clinical Neurology)

Robotic Urologic Surgery: Applications and Prospects

edited by

Guglielmo Mantica

submission deadline 25 Sep 2026 | Viewed by 308 | Submission Open

Keywords: urology; robotic surgery; RAPN; RARP; robotic procedures

(This special issue belongs to the Section General Surgery)

Innovative Approaches to the Epidemiology, Diagnosis, and Treatment of Systemic Sclerosis

edited by

Antonio-Javier Chamorro

submission deadline 25 Sep 2026 | Viewed by 278 | Submission Open

Keywords: systemic sclerosis; scleroderma; epidemiology; biomarkers; personalized therapy; therapeutic strategies

(This special issue belongs to the Section Clinical Neurology)

Current Treatment on Urinary Tract Infection

edited by

Biagio Barone

submission deadline 25 Sep 2026 | Viewed by 277 | Submission Open

Keywords: urinary tract infections (UTIs); antibiotic resistance; probiotics and alternative therapies; diagnostic advancements; urinary infection management

(This special issue belongs to the Section Nephrology & Urology)

Challenges and Clinical Surveillance in Cerebral Aneurysm Management

edited by Joseph Antonios

submission deadline 25 Sep 2026 | Viewed by 239 | Submission Open

Keywords: intracranial aneurysm; cerebral aneurysm surveillance; risk stratification; aneurysm progression; vascular inflammation

(This special issue belongs to the Section Clinical Neurology)

Diagnosis, Treatment and Prognosis of Benign Prostatic Hyperplasia and Prostate Cancer

edited by Christian Wetterauer

submission deadline 25 Sep 2026 | Viewed by 231 | Submission Open

Keywords: benign prostatic hyperplasia; prostate cancer; urology; urological oncology; oncological outcomes; risk stratification; benign prostatic obstruction; minimally invasive techniques; artificial intelligence

(This special issue belongs to the Section Nephrology & Urology)

Lifelong Care in Congenital Heart Disease

edited by

Cristina Ciuca

submission deadline 25 Sep 2026 | Viewed by 224 | Submission Open

Keywords: fetal echocardiography; pediatric cardiology; adults with congenital heart disease (ACHD); transition of care; cardio-obstetrics; heart failure; pregnancy; advanced imaging; echocardiography; cardiovascular risk prevention

(This special issue belongs to the Section Cardiovascular Medicine)

Mitral Valve Stenosis or Aortic Valve Stenosis: Progress from Diagnosis to Treatment

edited by Francesco Melillo

submission deadline 28 Sep 2026 | 3 articles | Viewed by 7957 | Submission Open

Keywords: aortic stenosis; mitral stenosis; TAVI

(This special issue belongs to the Section Cardiology)

Management of Female Pelvic Floor Disorders and Incontinence

edited by Luis López Fando

submission deadline 28 Sep 2026 | 3 articles | Viewed by 2566 | Submission Open

Keywords: pelvic floor disorders; urinary incontinence; pelvic organ prolapse; reconstructive urology; voiding dysfunction; multidisciplinary care; surgical techniques; urodynamics; patient-centered outcomes; digital learning in urology

(This special issue belongs to the Section Nephrology & Urology)

Current Challenges in Oral Surgery and Pathology

edited by

Christian Bacci

submission deadline 28 Sep 2026 | 2 articles | Viewed by 2202 | Submission Open

Keywords: oral medicine; oral pathology; oral surgery; ONJ; MRONJ; BRONJ; laser

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Recent Clinical Perspective in Kidney Transplantation

edited by Nikolina Bašić-Jukić

submission deadline 29 Sep 2026 | 7 articles | Viewed by 6384 | Submission Open

Keywords: kidney transplantation; outcomes; desensitization; xenotransplantation; transplant nephropathology; multiorgan transplantations; post-transplant complications; inequities in transplantation

(This special issue belongs to the Section Nephrology & Urology)

Glaucoma: Diagnosis and Management Insights

edited by

Stamatios Lampsas

and Efthymios Karmiris

submission deadline 29 Sep 2026 | 3 articles | Viewed by 2607 | Submission Open

Keywords: glaucoma; risk factors; progression; novel biomarkers; diagnosis; management

(This special issue belongs to the Section Ophthalmology)

New Insights into Cardiovascular Radiology

edited by Amalia Lupi and

Riccardo Cau

submission deadline 29 Sep 2026 | 3 articles | Viewed by 1850 | Submission Open

Keywords: CMR; tissue characterization; 4Dflow; CCTA; photon counting CT; plaque characterization

(This special issue belongs to the Section Nuclear Medicine & Radiology)

New Advances in Musculoskeletal Physiotherapy: Exercise, Manual Therapy and Invasive Physiotherapy

edited by

Marcos José Navarro-Santana

and Ignacio Cancela-Cilleruelo

submission deadline 30 Sep 2026 | 6 articles | Viewed by 22383 | Submission Open

Keywords: musculoskeletal disorders; exercise therapy; manual therapy; invasive physical therapy; rehabilitation

(This special issue belongs to the Section Orthopedics)

Catheter Ablation of Cardiac Arrhythmias: Current Updates and Perspectives: 2nd Edition

edited by

Shaojie Chen

submission deadline 30 Sep 2026 | 3 articles | Viewed by 7480 | Submission Open

Keywords: ablation; arrhythmia; electrophysiology; atrial fibrillation; atrial flutter; atrial tachycardia; mapping; supraventricular tachycardia; ventricular arrhythmia

(This special issue belongs to the Section Cardiology)

Clinical Updates on Dyslipidemia

edited by

Nathan Wong

submission deadline 30 Sep 2026 | 4 articles | Viewed by 5339 | Submission Open

Keywords: dyslipidemia; cardiovascular disease; prevention; treatment; risk factors

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Advances in Hepatology

edited by

Dimitrios S. Karagiannakis

and

Theodoros Androutsakos

submission deadline 30 Sep 2026 | 3 articles | Viewed by 4344 | Submission Open

Keywords: cirrhosis; portal hypertension; non-invasive tests; viral hepatitis; MASLD; HCC

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Artificial Intelligence in Women’s Health and Medicine: Improving Clinical Practice, Diagnosis, Treatment Management and Patient Experiences

edited by

Shivaram Poigai Arunachalam

and Nasibeh Zanjirani Farahani

submission deadline 30 Sep 2026 | 1 articles | Viewed by 4316 | Submission Open

Keywords: women’s health; artificial intelligence; machine learning; personalized medicine; reproductive health; health equity; social determinants of health; mental health; cancer; cardiovascular disease

(This special issue belongs to the Section Epidemiology & Public Health)

Modern Oral Surgery and Periodontology: Technological Advances, Innovation, and Clinical Applications

edited by Rafał Wiench and

Wojciech Niemczyk

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1505 | Submission Open

Keywords: oral surgery; periodontology; periodontal regeneration; implant dentistry; peri-implant diseases, guided surgery; biomaterials; platelet concentrates (PRF, PRP); bone regeneration

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Targeted Management of Orofacial Pain: From Pharmacology to Temporomandibular Joint Surgery

edited by

Matteo Val

Luca Guarda-Nardini

and Giulia Ottaviani

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1411 | Submission Open

Keywords: orofacial pain; chronic orofacial pain; neuropathic pain; pharmacological management; temporomandibular joint disorders; degenerative TMJ disease; conservative treatment; surgical management

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Burnout and Anxiety in Clinical and Occupational Contexts: Mental Health, Work-Related Stress, and Vulnerable Populations

edited by

Patricia Catalá

and

Cecilia Peñacoba-Puente

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1003 | Submission Open

Keywords: mental health; burnout; anxiety; occupational stress; women’s mental health; perinatal mental health; healthcare professionals; work-related stress; psychosocial factors; clinical interventions

(This special issue belongs to the Section Mental Health)

Interplay of Motility, Microbiota, and Function: New Insights into GI Disorders, IBS, and SIBO

edited by Tsachi Tsadok Perets

submission deadline 30 Sep 2026 | 1 articles | Viewed by 920 | Submission Open

Keywords: gastrointestinal motility; irritable bowel syndrome (IBS); small intestinal bacterial overgrowth (SIBO); gut microbiota; functional gastrointestinal disorders

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Updates and Advances in Aplastic Anemia and Other Bone Marrow Failures

edited by

Alicia Rovo

, Beatrice Drexler and Olaia Naveiras

submission deadline 30 Sep 2026 | Viewed by 486 | Submission Open

Keywords: aplastic anemia; severe aplastic anemia (SAA); bone marrow failures; paroxysmal nocturnal hemoglobinuria (PNH); inherited bone marrow failures

(This special issue belongs to the Section Hematology)

Acute Care Surgery: The Evolution of a Modern Specialty

edited by Mayur Narayan

submission deadline 30 Sep 2026 | Viewed by 373 | Submission Open

Keywords: acute care surgery; emergency surgery; health equity; global surgery; trauma care; surgical workforce; surgical in-novation; decision-making

(This special issue belongs to the Section Emergency Medicine)

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