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Glaucoma: Diagnosis and Management Insights

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Ophthalmology".

Deadline for manuscript submissions: 29 September 2026 | Viewed by 925

Special Issue Editors


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Guest Editor
2nd Department of Ophthalmology, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, 11528 Athens, Greece
Interests: glaucoma; risk factors; retinal diseases; diabetic retinopathy; glaucoma progression

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Guest Editor
Department of Ophthalmology, Airforce General Hospital, 251 Hellenic, Athens, Greece
Interests: keratoconus; cataract surgery; cornea; clinical research; ophthalmology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Glaucoma is a leading cause of irreversible blindness worldwide and remains a significant public health concern due to its silent progression and often late diagnosis. As its prevalence increases globally, particularly in aging populations, there is an urgent need for improved detection, evaluation, and management strategies.

The purpose could aim to provide a comprehensive and up-to-date overview of advances in the early detection, clinical evaluation, and therapeutic management of glaucoma. Given the complexity and heterogeneity of glaucomatous disease, there is a pressing need for continual innovation in diagnostic strategies, risk assessment, and individualized treatment approaches. This Special Issue aims to promote collaboration and knowledge exchange among ophthalmologists, clinicians, and researchers, with the overarching goal of enhancing both the scientific understanding and clinical management of glaucoma to improve patient care and outcomes.

We encourage the submission of original research articles and review papers that contribute to this evolving and vital field.

Dr. Stamatios Lampsas
Dr. Efthymios Karmiris
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • glaucoma
  • risk factors
  • progression
  • novel biomarkers
  • diagnosis
  • management

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Published Papers (1 paper)

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Review

10 pages, 241 KB  
Review
Glaucoma Management Therapies and Clinical Outcomes in an African Population: A Review of Prospective Studies
by Albert Kwadjo Amoah Andoh, Kwadwo Owusu Akuffo, Josephine Ampong, Kwadwo Antwi Appiagyei, Isaiah Osei Duah Junior, Simon Christoph König and Alexander Karl-Georg Schuster
J. Clin. Med. 2026, 15(5), 1837; https://doi.org/10.3390/jcm15051837 - 28 Feb 2026
Viewed by 692
Abstract
Glaucoma is a leading cause of irreversible blindness in Africa, with disease burden exacerbated by limited access to eye care, shortages of trained ophthalmologists, and socioeconomic disparities. This review synthesizes prospective and interventional studies evaluating glaucoma management modalities and associated clinical outcomes in [...] Read more.
Glaucoma is a leading cause of irreversible blindness in Africa, with disease burden exacerbated by limited access to eye care, shortages of trained ophthalmologists, and socioeconomic disparities. This review synthesizes prospective and interventional studies evaluating glaucoma management modalities and associated clinical outcomes in an African population. Trabeculectomy remains the predominant surgical intervention, achieving success rates of approximately 80%, with enhanced outcomes when augmented with anti-metabolites such as mitomycin-C or 5-fluorouracil. Laser-based interventions, including selective laser trabeculoplasty and transscleral cyclophotocoagulation, demonstrate moderate to high efficacy in reducing intraocular pressure, while nonpenetrating surgeries such as deep sclerectomy, viscocanalostomy, and canaloplasty provide substantial pressure reduction with fewer complications. Pediatric interventions, notably goniotomy, show efficacy in lowering intraocular pressure, although region-specific evidence remains limited. Evidence on pharmacological intervention remains scarce, fragmented, with high rates of non-adherence frequently reported, highlighting the need for rigorously-designed outcome-oriented studies to inform clinical practice. Adoption of newer surgical and laser techniques is constrained by cost, limited equipment, and insufficient subspeciality expertise. Improving glaucoma outcomes in Africa will require strategic expansion of access to effective treatments, strengthen local surgical capacity, and prioritize evidence-based research. Collectively, these efforts will provide a more robust framework to optimize glaucoma management and reduce the burden of irreversible blindness across the continent. Full article
(This article belongs to the Special Issue Glaucoma: Diagnosis and Management Insights)
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