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Challenges and Clinical Surveillance in Cerebral Aneurysm Management

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Neurology".

Deadline for manuscript submissions: 25 September 2026 | Viewed by 34

Special Issue Editor


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Guest Editor
Department of Neurosurgery, Yale School of Medicine, Yale University, New Haven, CT, USA
Interests: cerebrovascular disease; biomarkers; imaging biomarkers; precision medicine; hemodynamics

Special Issue Information

Dear Colleagues,

The management of intracranial aneurysms remains a major clinical challenge, particularly in determining which lesions are at highest risk for progression or rupture and how best to monitor them over time. Current surveillance strategies heavily rely on aneurysm morphology and imaging-based metrics, which incompletely capture the underlying biological processes driving aneurysm instability.

This Special Issue focuses on contemporary challenges in cerebral aneurysm management and emerging approaches to clinical surveillance. Topics of interest include advances in imaging and hemodynamic assessment, biomarkers of aneurysm progression, inflammatory and immune-mediated mechanisms of aneurysm disease, and novel risk stratification strategies. Particular emphasis is placed on translational frameworks that integrate biological, radiographic, and clinical data to improve patient-specific decision-making. By bringing together basic, translational, and clinical perspectives, this Special Issue aims to highlight evolving paradigms in aneurysm surveillance and identify innovative strategies that may ultimately refine how aneurysms are monitored and managed in clinical practice.

Dr. Joseph Antonios
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • intracranial aneurysm
  • cerebral aneurysm surveillance
  • risk stratification
  • aneurysm progression
  • vascular inflammation

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Published Papers

This special issue is now open for submission.
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