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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Advances in Kidney Transplantation

edited by

Florin Ioan Elec

and

Oana Antal

submission deadline 18 Sep 2026 | 7 articles | Viewed by 9533 | Submission Open

Keywords: kidney transplantation; immunosuppression; graft survival; donor risk assessment; post-transplant management; rejection and tolerance; precision medicine in transplantation

(This special issue belongs to the Section Nephrology & Urology)

Current Trends in Implant Dentistry

edited by Marco Toia

submission deadline 20 Sep 2026 | 9 articles | Viewed by 30351 | Submission Open

Keywords: digital implant planning; osseointegration; guided surgery (static and dynamic); bone regeneration; zygomatic and pterygoid implants; 3D previsualization; craniofacial analysis; peri-implant diseases; immediate loading

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Advancements in Spine Surgery: Best Practices and Outcomes

edited by

Mitsuru Yagi

submission deadline 20 Sep 2026 | 12 articles | Viewed by 27387 | Submission Open

Keywords: adult spinal deformity; scoliosis; frailty; biological age; big data analysis

(This special issue belongs to the Section Orthopedics)

Applied Cardiorespiratory Physiology in Critical Care Medicine

edited by

Athanasios Chalkias

and Paraskevi Tselioti

submission deadline 20 Sep 2026 | 5 articles | Viewed by 20912 | Submission Open

Keywords: applied physiology; critical care medicine; cardiovascular physiology; respiratory physiology

(This special issue belongs to the Section Anesthesiology)

Acute Pancreatitis and Its Complications: Current Diagnostics and Management

edited by

Beata Jabłońska

submission deadline 20 Sep 2026 | 5 articles | Viewed by 20237 | Submission Open

Keywords: acute pancreatitis; pancreas; pancreatic and peripancreatic necrosis; management; less invasive percutaneous radiological and endoscopic approaches

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Skin Disease and Inflammation

edited by

Taihao Quan

submission deadline 20 Sep 2026 | 4 articles | Viewed by 17217 | Submission Open

Keywords: inflammatory skin diseases; inflammation mechanisms; skin microbiome; psoriasis; eczema; rosacea

(This special issue belongs to the Section Dermatology)

Advances in Clinical Exercise for Health

edited by

Pedro Miguel Forte

and Joana Ribeiro

submission deadline 20 Sep 2026 | 8 articles | Viewed by 13625 | Submission Open

Keywords: clinical exercise science; physical activity; chronic disease prevention; biomechanics; healthy aging; physiology

(This special issue belongs to the Section Sports Medicine)

Coronary Artery Disease: Diagnosis, Treatment Challenges, and Emerging Therapy

edited by

Athanasios Samaras

and

Andreas S. Papazoglou

submission deadline 20 Sep 2026 | 5 articles | Viewed by 12959 | Submission Open

Keywords: coronary artery disease; percutaneous coronary intervention; cardiovascular disease; emerging therapies; treatment challenges; biomarkers; interventional cardiology

(This special issue belongs to the Section Cardiology)

Current Challenges and New Perspectives in Liver Transplantation

edited by

Anna Mrzljak

and

Quirino Lai

submission deadline 20 Sep 2026 | 11 articles | Viewed by 11201 | Submission Open

Keywords: liver transplantation; graft survival; immunosuppression; organ allocation; hepatocellular carcinoma; MASLD; donor shortage; transplant outcomes; innovation

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Perspectives on the Diagnosis and Treatment of Cardiomyopathies

edited by Luca Arcari

submission deadline 20 Sep 2026 | 5 articles | Viewed by 9449 | Submission Open

Keywords: cardiomyopathies; hypertrophic cardiomyopathy; dilated cardiomyopathy; cardiac amyloidosis; arrhythmogenic right ventricular cardiomyopathy; non-dilated left ventricular cardiomyopathy; cardiac magnetic resonance imaging; computed tomography; echocardiography; nuclear imaging

(This special issue belongs to the Section Cardiology)

Thoracic Surgery: State of the Art and Future Directions

edited by

Ugo Cioffi

and

Marco Scarci

submission deadline 20 Sep 2026 | 6 articles | Viewed by 9041 | Submission Open

Keywords: thoracic surgery; lung surgery; lung cancer; rib fractures; lung disease; pectus excavatum

(This special issue belongs to the Section Respiratory Medicine)

Cognitive Impairment, Dementia and Depression in Older Adults

edited by Seong Jae Kim and Ilhan Choo

submission deadline 20 Sep 2026 | 3 articles | Viewed by 7535 | Submission Open

Keywords: cognitive impairment; dementia; depression; Parkinson’s disease; artificial intelligence (AI); predictive modeling

(This special issue belongs to the Section Geriatric Medicine)

Maxillomandibular Growth, Reconstruction and Rehabilitation: Orthodontic, Prosthodontic and Surgical Interventions from Childhood to Adulthood

edited by Kamila Chęcińska and

Maciej Sikora

submission deadline 20 Sep 2026 | 5 articles | Viewed by 5641 | Submission Open

Keywords: maxillomandibular growth; orthodontics; prosthodontics; surgical interventions; childhood; adulthood; reconstruction; rehabilitation

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

New Advances in Systemic Lupus Erythematosus (SLE)

edited by

Chang-Hee Suh

submission deadline 20 Sep 2026 | 3 articles | Viewed by 5365 | Submission Open

Keywords: systemic lupus erythematosus; autoantibodies and biomarkers; lupus nephritis; new and novel treatments; targeted treatment or precision medicine; quality of life

(This special issue belongs to the Section Immunology & Rheumatology)

New Insights into the Management of Psoriasis and Immune-Mediated Dermatoses

edited by Federico Bardazzi and Riccardo Balestri

submission deadline 20 Sep 2026 | 6 articles | Viewed by 5234 | Submission Open

Keywords: psoriasis; immune-mediated inflammatory diseases; biologic therapy; small-molecule drugs; personalized treatment; real-world evidence; comorbidities; patient-centered care

(This special issue belongs to the Section Dermatology)

Advances in Antithrombotic Therapy in Cardiovascular Medicine

edited by Daniele Giacoppo and Antonio Greco

submission deadline 20 Sep 2026 | 6 articles | Viewed by 5026 | Submission Open

Keywords: anticoagulant; antiplatelet; antithrombotic therapy; cardiovascular pharmacotherapy; coronary artery disease; in-flammation; lipid-lowering drugs; lipid metabolism; residual cardiovascular risk; thrombosis

(This special issue belongs to the Section Cardiovascular Medicine)

Bladder Cancer: Diagnosis and Treatments

edited by

Stanislav Źiaran

submission deadline 20 Sep 2026 | 2 articles | Viewed by 4264 | Submission Open

Keywords: bladder cancer; urothelial cancer; radical cystectomy; targeted therapy; immunotherapy; non-muscle -invasive; muscle-invasive; chemotherapy

(This special issue belongs to the Section Nephrology & Urology)

Contemporary Oral and Maxillofacial Surgery: Expert Consensus and Best Practices

edited by

Jae-Yeol Lee

submission deadline 20 Sep 2026 | 5 articles | Viewed by 4237 | Submission Open

Keywords: facial trauma; TMJ disorders; implant and sinus surgery; sleep apnea; cosmetic and reconstructive surgery

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Postpartum Depression: What Happened to My Wife?

edited by

Sara Albuquerque

Ana Filipa Beato

and

Stephanie Alves

submission deadline 20 Sep 2026 | 4 articles | Viewed by 3887 | Submission Open

Keywords: postpartum depression; clinical and health psychology; perinatal trauma; clinical and health psychology; mental health and quality of life

(This special issue belongs to the Section Mental Health)

Liquid Biopsies in Oral Cancer: Advances and New Perspectives

edited by

Óscar Rapado-González

submission deadline 20 Sep 2026 | 1 articles | Viewed by 3885 | Submission Open

Keywords: oral cancer; oral potentially malignant disorders; liquid biopsies; saliva and blood biomarkers; circulating tumor cells (CTCs); cell-free DNA (cfDNA)/circulating tumor DNA (ctDNA); cell-free RNA (cfRNA); extracellular vesicles (EVs); genetic and epigenetic biomarkers; early detection; prognosis and therapy response prediction; precision medicine

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Minimally Invasive and Endoscopic Neurosurgery

edited by

Nikolaos Gkantsinikoudis

, Vassilios Tsitouras and Stylianos Kapetanakis

submission deadline 20 Sep 2026 | 1 articles | Viewed by 3852 | Submission Open

Keywords: traumatic brain injury; neuro-oncology; hydrocephalus and cerebrospinal fluid disorders; neuroendoscopy; endo-scopic neurosurgery; skull base surgery; vascular neurosurgery; functional neurosurgery; pediatric neurosurgey; minimally invasive spine surgery; endoscopic spine surgery; spine endoscopy

(This special issue belongs to the Section Clinical Neurology)

Residual Risk in High-Risk Patients Undergoing Percutaneous Coronary Intervention

edited by

Giampiero Vizzari

and

Antonio Micari

submission deadline 20 Sep 2026 | 1 articles | Viewed by 3775 | Submission Open

Keywords: cardiology; precision medicine; residual risk; acute coronary syndrome; percutaneous coronary intervention; PCI

(This special issue belongs to the Section Cardiology)

Innovations in Emergency and Critical Care Medicine

edited by Yoshiaki Iwashita

submission deadline 20 Sep 2026 | 3 articles | Viewed by 3672 | Submission Open

Keywords: emergency; artificial intelligence; Tele-ICU; point of care; electrical impedance tomography

(This special issue belongs to the Section Intensive Care)

Advancements and Challenges in Retina Surgery: Second Edition

edited by Joaquín Marticorena and

Javier Zarranz-Ventura

submission deadline 20 Sep 2026 | 2 articles | Viewed by 3635 | Submission Open

Keywords: retina; vitreoretinal diseases; vitreotomes; optical coherence tomography; vitreoretinal surgery

(This special issue belongs to the Section Ophthalmology)

Clinical Management in Chronic Pain: Innovations, Integration, and Interventions

edited by Giuliano Lo Bianco, Silvia Natoli and Sean Li

submission deadline 20 Sep 2026 | 3 articles | Viewed by 3498 | Submission Open

Keywords: chronic pain; clinical management; interventional pain medicine; spinal cord stimulation; regenerative medicine; diagnostic strategies; pain semeiotics; multidisciplinary approaches; personalized medicine; pain assessment; neuromodulation; evidence-based pain therapy

(This special issue belongs to the Section Clinical Neurology)

Personalized Treatments for Patients with Acute Lung Injury

edited by

Gary F. Nieman

submission deadline 20 Sep 2026 | 2 articles | Viewed by 3488 | Submission Open

Keywords: personalized; acute lung injury; acute respiratory distress syndrome (ARDS); ventilator-induced lung injury (VILI); pharmacotherapy; fluid resuscitation; phenotypes; mesenchymal stem cells; nano-systems; exosomes; biomarkers; computational models

(This special issue belongs to the Section Respiratory Medicine)

Clinical Research and Insights in Endometriosis

edited by

Nikolaos Machairiotis

submission deadline 20 Sep 2026 | 3 articles | Viewed by 3276 | Submission Open

Keywords: endometriosis; pelvic pain; infertility; inflammation; minimal access surgery; laparoscopy; hysteroscopy; robotics

(This special issue belongs to the Section Obstetrics & Gynecology)

Current Emerging Treatment Options in Atrial Fibrillation

edited by Hoang Nhat Pham and Amitoj Singh

submission deadline 20 Sep 2026 | 1 articles | Viewed by 3129 | Submission Open

Keywords: atrial fibrillation; AF ablation; lifestyle intervention; rhythm control; pulsed field ablation; antiarrhythmic drugs; direct oral anticoagulants

(This special issue belongs to the Section Cardiology)

Acute Ischemic Heart Disease: Risk Factors, Diagnosis, Management and Prognosis

edited by

Giuseppe De Luca

submission deadline 20 Sep 2026 | 3 articles | Viewed by 3028 | Submission Open

Keywords: acute coronary syndromes; STEMI; cardiogenic shock; primary angioplasty; antiplatelet therapies; anticoagulation; stent thrombosis; mechanical support devices; acute heart failure

(This special issue belongs to the Section Cardiology)

Advances and Challenges in Colorectal Cancer

edited by Vignesh Narasimhan

submission deadline 20 Sep 2026 | 4 articles | Viewed by 2929 | Submission Open

Keywords: anal fistula; advancement flap; ‎ligation of intersphincteric tract; haemorrhoid surgery; pilonidal surgery

(This special issue belongs to the Section Oncology)

Minimally Invasive Surgery: Challenges and Solutions in Clinical Practice

edited by

Giuseppe Cavallaro

and Alessia Fassari

submission deadline 20 Sep 2026 | 2 articles | Viewed by 2912 | Submission Open

Keywords: laparoscopic surgery; minimally invasive surgery; surgical challenges; clinical practice; surgical training; robotic-assisted surgery; artificial intelligence in surgery; laparoscopic instrumentation; intraoperative complications; surgical innovation; skill enhancement; surgical outcomes

(This special issue belongs to the Section General Surgery)

Bridging Bench, Bedside, and Beyond: Clinical and Translational Strategies for Pregnancy Complications

edited by

Thenral Socrates

and

Federica Piani

submission deadline 20 Sep 2026 | 3 articles | Viewed by 2910 | Submission Open

Keywords: high-risk pregnancy; cardiovascular complications; cardiometabolic complications; gestational diabetes; pregnancy complications; preeclampsia; hypertension; vascular disorders; endothelial dysfunction; clinical prediction; antenatal diagnosis; personalized treatment

(This special issue belongs to the Section Obstetrics & Gynecology)

Pediatric Otolaryngology: Clinical Advances and Challenges

edited by

Manabu Komori

and

Masaomi Motegi

submission deadline 20 Sep 2026 | 3 articles | Viewed by 2762 | Submission Open

Keywords: pediatric dizziness; laryngomalacia; subglottic stenosis; pediatric airway obstruction; intracapsular tonsillectomy; PITA (Powered Intracapsular Tonsillectomy and Adenoidectomy); pediatric sleep-disordered breathing; pediatric olfactory disorders; congenital anosmia

(This special issue belongs to the Section Clinical Pediatrics)

Clinical Research and Application of Artificial Intelligence and Deep Learning in Dentistry and Oral and Maxillofacial Surgery

edited by

Babak Saravi

Julian Lommen

and Lara Katharina Franziska Schorn

submission deadline 20 Sep 2026 | 4 articles | Viewed by 2747 | Submission Open

Keywords: artificial intelligence; deep learning; machine learning; oral and maxillofacial surgery; dentistry; medical imaging; clinical decision support

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Alopecia, Atopic Dermatitis and Other Chronic Inflammatory Skin Diseases: Pathogenesis, Comorbidities, and Precision Management

edited by

Trinidad Montero-Vilchez

and

Salvador Arias-Santiago

submission deadline 20 Sep 2026 | 5 articles | Viewed by 2734 | Submission Open

Keywords: alopecia; atopic dermatitis; chronic urticaria; prurigo nodularis; chronic pruritus; inflammatory skin diseases; biomarkers; biologics; JAK inhibitors; quality of life; precision medicine

(This special issue belongs to the Section Dermatology)

Up-to-Date Research on Nerve Ultrasound

edited by

Hubertus Axer

and Eman A. Tawfik

submission deadline 20 Sep 2026 | 1 articles | Viewed by 2676 | Submission Open

Keywords: peripheral nerve ultrasound; polyneuropathy; nerve trauma; plexus neuritis; nerve tumors; entrapment syndromes; ultrasound techniques; guidelines

(This special issue belongs to the Section Clinical Neurology)

Emerging Radiotherapy Technologies and Trends

edited by

Michele Fiore

submission deadline 20 Sep 2026 | 2 articles | Viewed by 2673 | Submission Open

Keywords: image-guided radiotherapy (IGRT); 4D radiotherapy; SBRT; radiomics; FLASH therapy; MR-guided radiotherapy

(This special issue belongs to the Section Oncology)

Management of Dyslipidemias: Enhancing Lipid Modification to Reduce Cardiovascular Risk: 2nd Edition

edited by

Daniel Gaudet

and Etienne Khoury

submission deadline 20 Sep 2026 | 1 articles | Viewed by 2520 | Submission Open

Keywords: cardiovascular disease; dyslipidemia; lipoprotein remnant; emerging lipid-lowering therapies; rare and severe causes of atherogenic lipid disorders; cardiovascular risk-related biomarkers; drug safety and efficacy

(This special issue belongs to the Section Cardiovascular Medicine)

Neurological Injury After Cardiac Arrest: Mechanisms, Prognostication, and Emerging Therapies

edited by

Marco Mion

and Nikos Gorgoraptis

submission deadline 20 Sep 2026 | 2 articles | Viewed by 2457 | Submission Open

Keywords: cardiac arrest; hypoxic–ischaemic brain injury; neuroprognostication; neuroprotection; biomarkers; targeted tem-perature management; multimodal monitoring; neurorehabilitation

(This special issue belongs to the Section Emergency Medicine)

Current Challenges and Approaches to Post-Traumatic Stress Disorder (PTSD)

edited by

Aron Tendler

submission deadline 20 Sep 2026 | 1 articles | Viewed by 2210 | Submission Open

Keywords: PTSD treatment; implementation; prevention; prevalence; risk factors

(This special issue belongs to the Section Mental Health)

Current Clinical Research in Oral Maxillofacial Surgery

edited by

Krzysztof Dowgierd

, Marcin Kozakiewicz, Łukasz J. Krakowczyk and Tadeusz Morawiec

submission deadline 20 Sep 2026 | 4 articles | Viewed by 2190 | Submission Open

Keywords: oral and maxillofacial surgery; craniofacial surgery; orthognathic surgery; maxillofacial trauma; head and neck oncology; microsurgical reconstruction; temporomandibular joint (TMJ); virtual surgical planning (VSP); patient-specific implants (PSI); complications and outcomes

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Diagnosis and Treatment of Uveitis

edited by

Nenad Vukojević

submission deadline 20 Sep 2026 | 2 articles | Viewed by 1980 | Submission Open

Keywords: uveitis; intraocular tumors; medical retina; pediatric retina

(This special issue belongs to the Section Ophthalmology)

Pediatric Oral Health: Developmental, Functional, and Special Care Perspectives

edited by

Vanessa Machado

and

Luísa Bandeira Lopes

submission deadline 20 Sep 2026 | 2 articles | Viewed by 1958 | Submission Open

Keywords: pediatric oral health; early childhood oral health; malocclusion; oral habits; craniofacial growth and development; dental development defects; dental trauma in children; orofacial functions; oral–systemic health; preventive and community dentistry; early oral intervention

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Cardiometabolic Insights into Metabolic Dysfunction: From Mechanisms to Therapeutic Strategies

edited by Alessandro Andreis,

Guglielmo Beccuti

and

Angelo Armandi

submission deadline 20 Sep 2026 | 1 articles | Viewed by 1869 | Submission Open

Keywords: cardiovascular complications; pharmacological; interventional strategies; cardiology; endocrinology; hepatology

(This special issue belongs to the Section Cardiology)

Clinical Advances in Autism Management

edited by

Justyna Podgórska-Bednarz

submission deadline 20 Sep 2026 | 1 articles | Viewed by 1862 | Submission Open

Keywords: autism spectrum disorder; diagnosis; child; adult; youth; early intervention; therapy; epidemiology; relatives; resources; limitations; problems; health; epidemiology; perspectives; organization

(This special issue belongs to the Section Mental Health)

Rehabilitation in Musculoskeletal Disease

edited by

Youngsook Bae

submission deadline 20 Sep 2026 | 3 articles | Viewed by 1839 | Submission Open

Keywords: musculoskeletal disease; stroke rehabilitation; physical therapy; rehabilitation; chronic pain; manual therapy; exercise intervention

(This special issue belongs to the Section Clinical Rehabilitation)

Atrial Fibrillation: Screening, Management and Outcomes

edited by Ahmed AlTurki and Vidal Essebag

submission deadline 20 Sep 2026 | 2 articles | Viewed by 1815 | Submission Open

Keywords: atrial fibrillation; ablation; pulmonary vein isolation; atrial fibrillation screening; wearable devices; anti-arrhythmic drugs; cardiovascular outcomes; subclinical atrial fibrillation

(This special issue belongs to the Section Cardiology)

Advances in Physical Therapy for Healthy Aging: Innovative and Functional Rehabilitation Approaches

edited by

Isabel Escobio-Prieto

submission deadline 20 Sep 2026 | 3 articles | Viewed by 1770 | Submission Open

Keywords: physical therapy; healthy aging; functional rehabilitation; therapeutic exercise; motor control; pelvic floor rehabilitation; preventive interventions

(This special issue belongs to the Section Clinical Rehabilitation)

Advances in Managing High-Risk Pregnancies: Innovations in Diagnosis, Prevention and Clinical Care

edited by

Dominique A. Badr

, Vivien Dütemeyer and Jacques Jani

submission deadline 20 Sep 2026 | 3 articles | Viewed by 1721 | Submission Open

Keywords: high-risk pregnancy; maternal–fetal medicine; prenatal diagnosis; fetal growth restriction; preeclampsia; preterm birth; biomarkers; maternal comorbidities; clinical imaging; precision obstetrics

(This special issue belongs to the Section Obstetrics & Gynecology)

Current Advances in Artificial Intelligence in Oral Cancer Research, Early Diagnosis, and Personalized Therapy

edited by Aminollah Khormali

submission deadline 20 Sep 2026 | 1 articles | Viewed by 1607 | Submission Open

Keywords: artificial intelligence; precision oncology; digital pathology; deep learning; early cancer detection; predic-tive modeling; oral cancer diagnostics

(This special issue belongs to the Section Oncology)

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