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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Advances in Clinical Epidemiological Research Methods

edited by

Dorota Sys

and Anna Scholz

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1035 | Submission Open

Keywords: clinical epidemiology; research methodology; observational studies; causal inference; real-world data; machine learning; bias control

(This special issue belongs to the Section Clinical Research Methods)

Esophageal and Upper Interventional Endoscopy and Surgery: Latest Advances and Prospects

edited by Giulia Gibiino

submission deadline 20 Mar 2026 | 1 articles | Viewed by 925 | Submission Open

Keywords: gastric preneoplastic and neoplastic lesions; endoscopic submucosal dissection (ESD); endoscopic full-thickness resection (EFTR); subepithelial upper GI lesions; duodenal adenomas; esophageal stenting

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Maxillomandibular Growth, Reconstruction and Rehabilitation: Orthodontic, Prosthodontic and Surgical Interventions from Childhood to Adulthood

edited by Kamila Chęcińska and

Maciej Sikora

submission deadline 20 Mar 2026 | 1 articles | Viewed by 876 | Submission Open

Keywords: maxillomandibular growth; orthodontics; prosthodontics; surgical interventions; childhood; adulthood; reconstruction; rehabilitation

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Treatment Strategies for Prostate Cancer: An Update

edited by

Antonio Andrea Grosso

submission deadline 20 Mar 2026 | 1 articles | Viewed by 837 | Submission Open

Keywords: prostate cancer; robotic surgery; uro-oncology; focal therapy; single-port; radiotherapy

(This special issue belongs to the Section Nephrology & Urology)

Clinical Advances in Autism Management

edited by

Justyna Podgórska-Bednarz

submission deadline 20 Mar 2026 | 1 articles | Viewed by 799 | Submission Open

Keywords: autism spectrum disorder; diagnosis; child; adult; youth; early intervention; therapy; epidemiology; relatives; resources; limitations; problems; health; epidemiology; perspectives; organization

(This special issue belongs to the Section Mental Health)

Advances in Diagnosis and Treatment of Endometriosis

edited by

Arrigo Fruscalzo

and

Anis Feki

submission deadline 20 Mar 2026 | 2 articles | Viewed by 782 | Submission Open

Keywords: endometriosis; adenomyosis; diagnosis; classification; therapy; progesterone

(This special issue belongs to the Section Obstetrics & Gynecology)

Update on Minimally Invasive Gynecologic Surgery

edited by

Greg J. Marchand

submission deadline 20 Mar 2026 | 2 articles | Viewed by 701 | Submission Open

Keywords: minimally invasive gynecologic surgery (MIGS); obstetrics and gynecology; single-port laparoscopy; hysterectomy; robotic surgery

(This special issue belongs to the Section Obstetrics & Gynecology)

Latest Advances in Minimally Invasive Spine Surgery

edited by Fabian Sommer and

Roger Härtl

submission deadline 20 Mar 2026 | 1 articles | Viewed by 680 | Submission Open

Keywords: minimally invasive spine surgery (MISS); advances in spine surgery; future directions of MISS; navigation and orientation; intramedullary/extramedullary tumor resections; emerging technologies in MISS (robotics; augmented reality; artificial intelligence; etc.); degenerative spine; patient safety in MISS

(This special issue belongs to the Section Clinical Neurology)

Pediatric Otolaryngology: Clinical Advances and Challenges

edited by

Manabu Komori

and

Masaomi Motegi

submission deadline 20 Mar 2026 | 1 articles | Viewed by 564 | Submission Open

Keywords: pediatric dizziness; laryngomalacia; subglottic stenosis; pediatric airway obstruction; intracapsular tonsillectomy; PITA (Powered Intracapsular Tonsillectomy and Adenoidectomy); pediatric sleep-disordered breathing; pediatric olfactory disorders; congenital anosmia

(This special issue belongs to the Section Clinical Pediatrics)

Minimally Invasive and Endoscopic Neurosurgery

edited by

Nikolaos Gkantsinikoudis

, Vassilios Tsitouras and Stylianos Kapetanakis

submission deadline 20 Mar 2026 | 1 articles | Viewed by 553 | Submission Open

Keywords: traumatic brain injury; neuro-oncology; hydrocephalus and cerebrospinal fluid disorders; neuroendoscopy; endo-scopic neurosurgery; skull base surgery; vascular neurosurgery; functional neurosurgery; pediatric neurosurgey; minimally invasive spine surgery; endoscopic spine surgery; spine endoscopy

(This special issue belongs to the Section Clinical Neurology)

Innovations in Emergency and Critical Care Medicine

edited by Yoshiaki Iwashita

submission deadline 20 Mar 2026 | Viewed by 531 | Submission Open

Keywords: emergency; artificial intelligence; Tele-ICU; point of care; electrical impedance tomography

(This special issue belongs to the Section Intensive Care)

Challenges and Innovations in Thrombosis and Haemostasis

edited by Vasiliki Danilatou and Fotios I. Girtovitis

submission deadline 20 Mar 2026 | Viewed by 447 | Submission Open

Keywords: air pollution and thrombosis; antiphospholipid syndrome; antithrombotic therapy; arterial thrombosis; artificial intelligence in thrombosis and haemostasis; biology of arterial thrombosis; biomarkers in thrombosis and haemostasis; cancer-associated thrombosis; clinical decision support; current concepts and novel targets for antiplatelet treatments; digital health in heamostasis and thrombosis; endotheliopathy and thrombosis; ethical challenges in thrombosis care; hemophilia and von willebrand disease; innovative therapies in thrombosis and haemostasis; pediatric thrombosis; platelet biology and function: new concepts and clinical perspectives; rare blood disorders; thrombophilia; thrombosis and hemostasis guidelines; thrombosis in pregnancy; thrombo-inflammation; trauma-induced coagulopathy; venous thromboembolism

(This special issue belongs to the Section Vascular Medicine)

Recent Advances in Head and Neck Surgery

edited by Lisa Catarzi,

Olindo Massarelli

and

Guido Gabriele

submission deadline 20 Mar 2026 | Viewed by 395 | Submission Open

Keywords: head and neck surgery; reconstructive surgery; microsurgical reconstruction; new technologies; computer-assisted surgery; surgical innovation; post-operative care

(This special issue belongs to the Section Otolaryngology)

Bridging Bench, Bedside, and Beyond: Clinical and Translational Strategies for Pregnancy Complications

edited by

Thenral Socrates

and

Federica Piani

submission deadline 20 Mar 2026 | 1 articles | Viewed by 351 | Submission Open

Keywords: high-risk pregnancy; cardiovascular complications; cardiometabolic complications; gestational diabetes; pregnancy complications; preeclampsia; hypertension; vascular disorders; endothelial dysfunction; clinical prediction; antenatal diagnosis; personalized treatment

(This special issue belongs to the Section Obstetrics & Gynecology)

Vertigo and Dizziness in Children: Clinical Updates

edited by

Eduardo Martin Sanz

submission deadline 20 Mar 2026 | Viewed by 240 | Submission Open

Keywords: vertigo; dizziness; children; vestibular disorders; otorhinolaryngology

(This special issue belongs to the Section Clinical Pediatrics)

Clinical Advances in Musculoskeletal Disorders: 2nd Edition

edited by

Peter V. Giannoudis

and Sushrut Babhulkar

submission deadline 20 Mar 2026 | Viewed by 214 | Submission Open

Keywords: musculoskeletal disorders; disability; pain; inflammation; arthritis

(This special issue belongs to the Section Clinical Rehabilitation)

Up-to-Date Research on Nerve Ultrasound

edited by

Hubertus Axer

and Eman A. Tawfik

submission deadline 20 Mar 2026 | Viewed by 211 | Submission Open

Keywords: peripheral nerve ultrasound; polyneuropathy; nerve trauma; plexus neuritis; nerve tumors; entrapment syndromes; ultrasound techniques; guidelines

(This special issue belongs to the Section Clinical Neurology)

Postpartum Depression: What Happened to My Wife?

edited by

Sara Albuquerque

, Ana Filipa Beato and

Stephanie Alves

submission deadline 20 Mar 2026 | Viewed by 198 | Submission Open

Keywords: postpartum depression; clinical and health psychology; perinatal trauma; clinical and health psychology; mental health and quality of life

(This special issue belongs to the Section Mental Health)

Modern Gynecological Surgery: Clinical Updates and Perspectives

edited by

Rudy Leon De Wilde

Harald Krentel

and Maya Sophie de Wilde

submission deadline 20 Mar 2026 | Viewed by 187 | Submission Open

Keywords: gynecological diseases; gynecological surgery; surgical options; individual treatment; women’ s health care

(This special issue belongs to the Section Obstetrics & Gynecology)

Emerging Radiotherapy Technologies and Trends

edited by

Michele Fiore

submission deadline 20 Mar 2026 | Viewed by 175 | Submission Open

Keywords: image-guided radiotherapy (IGRT); 4D radiotherapy; SBRT; radiomics; FLASH therapy; MR-guided radiotherapy

(This special issue belongs to the Section Oncology)

Contemporary Oral and Maxillofacial Surgery: Expert Consensus and Best Practices

edited by

Jae-Yeol Lee

submission deadline 20 Mar 2026 | Viewed by 170 | Submission Open

Keywords: facial trauma; TMJ disorders; implant and sinus surgery; sleep apnea; cosmetic and reconstructive surgery

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Management in Chronic Pain: Innovations, Integration, and Interventions

edited by Giuliano Lo Bianco, Silvia Natoli and Sean Li

submission deadline 20 Mar 2026 | Viewed by 164 | Submission Open

Keywords: chronic pain; clinical management; interventional pain medicine; spinal cord stimulation; regenerative medicine; diagnostic strategies; pain semeiotics; multidisciplinary approaches; personalized medicine; pain assessment; neuromodulation; evidence-based pain therapy

(This special issue belongs to the Section Clinical Neurology)

Rehabilitation in Musculoskeletal Disease

edited by

Youngsook Bae

submission deadline 20 Mar 2026 | Viewed by 163 | Submission Open

Keywords: musculoskeletal disease; stroke rehabilitation; physical therapy; rehabilitation; chronic pain; manual therapy; exercise intervention

(This special issue belongs to the Section Clinical Rehabilitation)

Recent Advances in Vitreoretinal Surgery: 2nd Edition

edited by

Lihteh Wu

submission deadline 20 Mar 2026 | Viewed by 160 | Submission Open

Keywords: vitrectomy; retinal detachment; macular holes; pediatric vitreoretinal surgery; vitrectomy instrumentation; macular surgery; complex retinal detachments; vitreoretinal surgery

(This special issue belongs to the Section Ophthalmology)

Machine Learning in Vascular Surgery

edited by

George N. Kouvelos

Konstantinos Spanos

and

Konstantinos Dakis

submission deadline 20 Mar 2026 | Viewed by 147 | Submission Open

Keywords: machine learning; artificial intelligence; vascular surgery

(This special issue belongs to the Section Vascular Medicine)

Periodontitis and Systemic Health: Exploring the Oral-Systemic Connection

edited by

Yiorgos Bobetsis

and Phoebus Madianos

submission deadline 20 Mar 2026 | Viewed by 147 | Submission Open

Keywords: periodontal disease; systemic diseases; cardiovascular disease; diabetes mellitus; adverse pregnancy outcomes; respiratory disease; neurodegenerative disorders; obesity; respiratory diseases; chronic kidney disease

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Applications of Echocardiographic Techniques in Cardiovascular Diagnostics

edited by Gianpiero Italiano and

Laura Fusini

submission deadline 20 Mar 2026 | Viewed by 141 | Submission Open

Keywords: echocardiography; cardiovascular diagnostics; 3D echocardiography; strain imaging; speckle-tracking echocardi-ography; valvular heart disease; heart failure; interventional echocardiography; stress echocardiography; car-dio-oncology; artificial intelligence

(This special issue belongs to the Section Cardiovascular Medicine)

Advances in the Field of Radiation Oncology: An Update

edited by

Jack Phan

and

Anna Lee

submission deadline 20 Mar 2026 | Viewed by 141 | Submission Open

Keywords: radiation oncology; image-guided radiotherapy (IGRT); immunotherapy; machine learning; radiation

(This special issue belongs to the Section Oncology)

Clinical Advances in Prosthetic Joint Infection

edited by

Mattia Loppini

submission deadline 20 Mar 2026 | Viewed by 140 | Submission Open

Keywords: total hip revision; total knee revision; complications; periprosthetic joint infections; diagnostics

(This special issue belongs to the Section Orthopedics)

Clinical Advances in Neurorehabilitation

edited by

Giuliana Vezzadini

and

Michela Candini

submission deadline 20 Mar 2026 | Viewed by 137 | Submission Open

Keywords: neurorehabilitation; robotics; artificial intelligence; neurodegenerative diseases; Parkinson’ s disease; stroke

(This special issue belongs to the Section Clinical Rehabilitation)

Bladder Cancer: Diagnosis and Treatments

edited by

Stanislav Źiaran

submission deadline 20 Mar 2026 | Viewed by 134 | Submission Open

Keywords: bladder cancer; urothelial cancer; radical cystectomy; targeted therapy; immunotherapy; non-muscle -invasive; muscle-invasive; chemotherapy

(This special issue belongs to the Section Nephrology & Urology)

Current Challenges in Oral Surgery and Pathology

edited by

Christian Bacci

submission deadline 20 Mar 2026 | Viewed by 123 | Submission Open

Keywords: oral medicine; oral pathology; oral surgery; ONJ; MRONJ; BRONJ; laser

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Challenges and Future Directions of Interstitial Lung Disease

edited by

Yoshiaki Zaizen

submission deadline 20 Mar 2026 | Viewed by 120 | Submission Open

Keywords: interstitial lung disease; progressive pulmonary fibrosis; early detection; clinical diagnosis; multidisciplinary discussion; treatment; non-pharmacological therapy; end-of-life care; patient-centered management

(This special issue belongs to the Section Respiratory Medicine)

Atrial Fibrillation: Screening, Management and Outcomes

edited by Ahmed AlTurki and Vidal Essebag

submission deadline 20 Mar 2026 | Viewed by 117 | Submission Open

Keywords: atrial fibrillation; ablation; pulmonary vein isolation; atrial fibrillation screening; wearable devices; anti-arrhythmic drugs; cardiovascular outcomes; subclinical atrial fibrillation

(This special issue belongs to the Section Cardiology)

Exercise and Chronic Pain

edited by Nuria Marín-Jiménez and Milkana Borges-Cosic

submission deadline 20 Mar 2026 | Viewed by 116 | Submission Open

Keywords: chronic pain; exercise therapy; physical activity; fitness; pain management; quality of life; non-pharmacological interventions

(This special issue belongs to the Section Sports Medicine)

Clinical Advances in Maternal–Fetal Medicine: 2nd Edition

edited by

Erich Cosmi

submission deadline 20 Mar 2026 | Viewed by 110 | Submission Open

Keywords: precision medicine; omics; clinical; fetus; Doppler

(This special issue belongs to the Section Obstetrics & Gynecology)

Emerging Insights into Glaucoma, Cataracts, and Refractive Surgery

edited by

Michele Lanza

submission deadline 20 Mar 2026 | Viewed by 108 | Submission Open

Keywords: trabeculoplasty; MIGS; MIBS; trabeculectomy; IOL; biometry; phacoemulsification; femto-cataract; refractive cataract; excimer laser; PRK; femto; LASIK; SMILE; aberrometry; tomography

(This special issue belongs to the Section Ophthalmology)

Minimally Invasive Thoracic Surgery: State of the Art and Future Perspectives

edited by Dustin M. Walters

submission deadline 20 Mar 2026 | Viewed by 107 | Submission Open

Keywords: thoracic surgery; perioperative outcomes; lung cancer resection; minimally invasive surgery; robotic thoracic surgery

(This special issue belongs to the Section Respiratory Medicine)

Intracranial Aneurysms: What Do We Know So Far?

edited by Alessio Albanese and Giuseppe Esposito

submission deadline 20 Mar 2026 | Viewed by 105 | Submission Open

Keywords: intracranial aneurysms; clipping; endovascular therapy; stenting; coiling; cerebral vasospasm; cerebrovascular diseases; microneurosurgery; subarachnoid hemorrhage; bypass

(This special issue belongs to the Section Clinical Neurology)

Clinical Advances in Laryngeal Cancer

edited by

Gunnar Wichmann

and

Theresa Wald

submission deadline 20 Mar 2026 | Viewed by 103 | Submission Open

Keywords: head and neck cancer (HNC); laryngeal cancer; larynx organ preservation; immuno-oncology; biomarker; prognostic factor; genetic risk factors; outcome research

(This special issue belongs to the Section Otolaryngology)

Advances and Challenges in Colorectal Cancer

edited by Vignesh Narasimhan

submission deadline 20 Mar 2026 | Viewed by 101 | Submission Open

Keywords: anal fistula; advancement flap; ‎ ligation of intersphincteric tract; haemorrhoid surgery; pilonidal surgery

(This special issue belongs to the Section Oncology)

Emerging Research in Cancer Survivorship

edited by

Elham Mohebbi

submission deadline 20 Mar 2026 | Viewed by 98 | Submission Open

Keywords: cancer survivorship; clinical epidemiology; quality of life; health system; sexual health; mental health; comorbidities; pain management; tobacco cessation; alcohol abstinence; diet

(This special issue belongs to the Section Epidemiology & Public Health)

Advancements and Challenges in Retina Surgery: Second Edition

edited by Joaquín Marticorena and

Javier Zarranz-Ventura

submission deadline 20 Mar 2026 | Viewed by 95 | Submission Open

Keywords: retina; vitreoretinal diseases; vitreotomes; optical coherence tomography; vitreoretinal surgery

(This special issue belongs to the Section Ophthalmology)

Acute Cardiovascular Care in Cardio-Oncology: Present Challenges and Future Pathways

edited by

Raffaele Bugiardini

and Maria Bergami

submission deadline 20 Mar 2026 | Viewed by 93 | Submission Open

Keywords: cardiotoxicity; cardio-oncology; acute cardiovascular care; acute cardiovascular complications; disparities in care

(This special issue belongs to the Section Cardiovascular Medicine)

Rectal Cancer: Screening, Treatment and Prevention

edited by Fernando Mendoza-Moreno

submission deadline 20 Mar 2026 | Viewed by 84 | Submission Open

Keywords: rectal cancer; cancer screening; neoadjuvant therapy; minimally invasive surgery; oncologic outcomes; multidiscipli-nary care; health disparities

(This special issue belongs to the Section Oncology)

Current Paradigms in Pulmonary Vascular Disease: Past, Present and Future

edited by Parth M. Rali

submission deadline 20 Mar 2026 | Viewed by 83 | Submission Open

Keywords: pulmonary hypertension (PH); pulmonary embolism (PE); rare pulmonary vascular disorders; novel therapeutics; di-agnostic innovations

(This special issue belongs to the Section Respiratory Medicine)

Updates in the Use of Pharmacogenetics in Clinical Practice

edited by Rocío Morón Romero and Xando Díaz-Villamarín

submission deadline 20 Mar 2026 | Viewed by 82 | Submission Open

Keywords: pharmacogenetics; personalized medicine; clinical implementation; drug response; pharmacogenomics; precision medicine; healthcare integration; decision support; clinical implications of genetic testing

(This special issue belongs to the Section Pharmacology)

Clinical Updates and Perspectives on Subarachnoid Hemorrhage: 2nd Edition

edited by

Fusao Ikawa

submission deadline 20 Mar 2026 | Viewed by 81 | Submission Open

Keywords: subarachnoid hemorrhage; outcome of subarachnoid hemorrhage; delayed cerebral ischemia; ruptured cerebral aneurysm; unruptured cerebral aneurysm; artificial intelligence; epidemiology

(This special issue belongs to the Section Clinical Neurology)

Personalized Medicine and Treatment in Inflammatory Bowel Diseases

edited by Carmen Monica Preda and

Cristian George Tieranu

submission deadline 21 Mar 2026 | Viewed by 129 | Submission Open

Keywords: personalized medicine; inflammatory bowel diseases (IBDs); Crohn’ s disease; ulcerative colitis; biomarkers; pharmacogenomics; microbiome; anti-TNF therapy; precision medicine; machine learning

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Perspectives on Foot and Ankle Surgery

edited by Kenichiro Nakajima

submission deadline 24 Mar 2026 | 3 articles | Viewed by 8222 | Submission Open

Keywords: foot and ankle; minimally invasive surgery; surgical techniques; new technologies; diagnosis; clinical assessment

(This special issue belongs to the Section Orthopedics)

Displaying special issue 551-600 on page 12 of 31.

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