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Personalized Medicine and Treatment in Inflammatory Bowel Diseases

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Gastroenterology & Hepatopancreatobiliary Medicine".

Deadline for manuscript submissions: 21 March 2026 | Viewed by 6

Special Issue Editor


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Guest Editor
1. Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania
2. Department of Gastroenterology, Fundeni Clinic Institute, 022328 Bucharest, Romania
Interests: ulcerative colitis; Crohn’s disease; inflammatory bowel diseases; endoscopy
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Personalized medicine is transforming the treatment of inflammatory bowel diseases (IBDs), including Crohn’s disease and ulcerative colitis, by allowing us to tailor therapies to individual patient profiles. This approach leverages advancements in genomics, microbiome analysis, and immune profiling to identify biomarkers that predict disease progression and treatment responses. Traditional IBD management often follows a trial-and-error method, but personalized strategies can be designed to optimize efficacy while minimizing side effects. For instance, pharmacogenomics helps determine optimal drug choices (e.g., anti-TNF agents, JAK inhibitors) based on genetic makeup, while microbiome modulation offers insights into diet and probiotic interventions. Machine learning further enhances decision-making through the integration of multi-omics data. There are still challenges to overcome, such as high costs and data interpretation complexities, but there is significant potential for improvements in remission rates and quality of life. As research progresses, personalized medicine shows promise in redefining IBD care, emphasizing precise and patient-specific solutions.

Dr. Carmen Monica Preda
Guest Editor

Manuscript Submission Information

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Keywords

  • personalized medicine
  • inflammatory bowel diseases (IBDs)
  • Crohn’s disease
  • ulcerative colitis
  • biomarkers
  • pharmacogenomics
  • microbiome
  • anti-TNF therapy
  • precision medicine
  • machine learning

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Published Papers

This special issue is now open for submission.
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