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Intracranial Aneurysms: What Do We Know So Far?

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Neurology".

Deadline for manuscript submissions: 20 March 2026 | Viewed by 8

Special Issue Editors


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Guest Editor
Department of Neurosurgery, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy
Interests: vascular neurosurgery; intracranial aneurysms; neuro-oncology; brain tumors; skull base neurosurgery
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
1. Department of Neurosurgery, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland
2. Zurich Microsurgery Lab, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland
Interests: vascular neurosurgery; intracranial aneurysms; cerebral revascularization; neuro-oncology; skull base neurosurgery
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The increasing accessibility of advanced imaging techniques has led to a rise in the incidental detection of intracranial aneurysms (IAs), marking a significant shift in the landscape of neurovascular care. As a result, the incidence of unruptured intracranial aneurysms has risen steeply, presenting increasing challenges in the decision-making process and the evaluation of treatment strategies. Contemporary management protocols mostly emphasize endovascular treatment over surgical approaches, reflecting the growing body of evidence supporting less invasive methods. Notably, endovascular modalities such as coiling, intra-aneurysmal devices, stenting, flow diversion, and bioactive coatings have evolved substantially over the past three decades, becoming integral to modern IA management. However, long-term follow-up data after endovascular treatment remain limited, and a notable trend of aneurysm recurrence and an increasing need for re-treatment have been documented. Furthermore, this evolving landscape has led to a growing prevalence of complex aneurysms requiring greater surgical skills and experience despite reduced surgical exposure. Advanced pre- and intraoperative tools and technologies in supporting safe surgical clipping and bypass are easily available today and universally affordable, ensuring reduced complication rates. Therefore, surgical treatment remains an effective option for selected cases.

In light of the global demand for results derived from multicentric analyses on long-term follow-up, and the subsequent definition of up-to-date recommendations, we welcome authors to contribute to the present Special Issue, titled “Intracranial Aneurysms: What Do We Know So Far?”, with original papers, multicentric studies and experiences, meta-analyses, and systematic reviews exploring the dynamic field of cerebrovascular treatment, and the latest developments in the treatment of intracranial aneurysms.

You may choose our Joint Special Issue in Brain Sciences.

Dr. Alessio Albanese
Dr. Giuseppe Esposito
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • intracranial aneurysms
  • clipping
  • endovascular therapy
  • stenting
  • coiling
  • cerebral vasospasm
  • cerebrovascular diseases
  • microneurosurgery
  • subarachnoid hemorrhage
  • bypass

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Published Papers

This special issue is now open for submission.
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