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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Blood Cancers: Current Status and Future Challenges

edited by

Salvatore Perrone

and Massimo Breccia

submission deadline 15 Jun 2026 | 1 articles | Viewed by 1494 | Submission Open

Keywords: acute myeloid leukemia; hematology; leukemia; venetoclax; blood disorders

(This special issue belongs to the Section Hematology)

Clinical Updates on Valvular Heart Diseases: A New Era in Personalized Treatment

edited by Massimiliano Mariani

submission deadline 15 Jun 2026 | 2 articles | Viewed by 1405 | Submission Open

Keywords: valvular heart disease; structural heart intervention; imaging in valve disease; interventional echocardiography; minimally invasive cardiac surgery; aortic valve intervention; tricuspid valve intervention; valve intervention in GUCH; patient-specific therapy; advanced diagnostic techniques; gutting-edge cardiac imaging; catheter-based interventions; innovative cardiac therapies

(This special issue belongs to the Section Cardiology)

Perioperative Management in Thoracic Surgery: Current Advances and Future Perspectives

edited by

Roberto Cascone

and

Alfonso Fiorelli

submission deadline 15 Jun 2026 | 1 articles | Viewed by 990 | Submission Open

Keywords: thoracic surgery; perioperative care; ERAS; minimally invasive surgery; interventional pulmonology; preoperative assessment; postoperative management; surgical outcomes; multidisciplinary approach; technology in surgery

(This special issue belongs to the Section Respiratory Medicine)

Cardiac Arrest: Strategies, Innovations, and Improvements in Outcomes

edited by

Kei Hayashida

submission deadline 15 Jun 2026 | Viewed by 982 | Submission Open

Keywords: cardiac arrest; cardiopulmonary resuscitation; post-cardiac arrest syndrome; neurological outcomes

(This special issue belongs to the Section Cardiology)

New Clinical Advances in Pediatric Asthma

edited by

Davor Plavec

submission deadline 15 Jun 2026 | 1 articles | Viewed by 910 | Submission Open

Keywords: pediatric asthma; clinical management; treatment advances; diagnostic advances; biologic therapy; inhaled steroids; control of asthma; exacerbation prevention; quality of life

(This special issue belongs to the Section Clinical Pediatrics)

Transjugular Intrahepatic Portosystemic Shunt: Challenges and Perspectives—2nd Edition

edited by

Lorenzo Ridola

, Stefania Gioia and

Silvia Nardelli

submission deadline 15 Jun 2026 | 1 articles | Viewed by 645 | Submission Open

Keywords: hepatic encephalopathy; spontaneous portal-systemic shunts; transjugular intrahepatic portosystemic shunt; cirrhosis; portal hypertension; sarcopenia; myosteatosis; gastrointestinal bleeding; ascites; non cirrhotic portal hypertension

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Congenital Heart Diseases: Epidemiology, Treatment and Lifelong Support

edited by Sebastian Freilinger,

Renate Oberhoffer-Fritz

Harald Kaemmerer

and Oliver Dewald

submission deadline 15 Jun 2026 | 1 articles | Viewed by 548 | Submission Open

Keywords: congenital heart disease (CHD); adults with CHD; epidemiology; comorbidities; intervention; surgical treatment; psychological aspects; quality of life (QoL); risk factors; rehabilitation; health promotion; prevention; health literacy; physical activity; lifelong support

(This special issue belongs to the Section Cardiology)

Dental Implantology: Clinical Updates and Perspectives—2nd Edition

edited by

Roberta Gasparro

submission deadline 15 Jun 2026 | 1 articles | Viewed by 332 | Submission Open

Keywords: dental implantology; reconstructive surgery; biomaterials; tissue engineering; regenerative medicine; digital dentis-try; periimplantitis; peri-implant soft tissues

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Advances in Cancer Imaging

edited by

Paul-Andrei Ștefan

submission deadline 15 Jun 2026 | Viewed by 225 | Submission Open

Keywords: pelvic oncology; cancer imaging; CT; MRI; tumor staging; treatment response; morphological criteria; gynecologic cancer; bladder cancer; rectal cancer; artificial intelligence; radiomics; texture analysis; image biomarkers; clinical imaging

(This special issue belongs to the Section Oncology)

New Advances of Infectious Disease Epidemiology

edited by

Francisco Guillen-Grima

submission deadline 15 Jun 2026 | Viewed by 100 | Submission Open

Keywords: infectious disease epidemiology; genomic sequencing; computational modeling; collaborative surveillance; digital epidemiology; one health; pandemic intelligence; public health data integration; emerging pathogens; epidemiologic insights

(This special issue belongs to the Section Epidemiology & Public Health)

Traumatic Brain Injury: Clinical Diagnosis and Management

edited by Alessio Caccioppola

submission deadline 15 Jun 2026 | Viewed by 98 | Submission Open

Keywords: glasgow coma scale; intracranial pressure monitoring; traumatic brain injury; diffuse axonal injury; post-traumatic epilepsy; decompressive craniectomy; neuromonitoring

(This special issue belongs to the Section Brain Injury)

Clinical Advancements in Foot and Ankle Surgery: 2nd Edition

edited by

Ho-seong Lee

submission deadline 15 Jun 2026 | Viewed by 86 | Submission Open

Keywords: flat foot; hindfoot motion; diabetic foot; hallux valgus; foot infection; foot trauma

(This special issue belongs to the Section Orthopedics)

Current Challenges and Opportunities in Assisted Reproductive Technologies

edited by Andrea Milostić-Srb and

Davor Jezek

submission deadline 15 Jun 2026 | Viewed by 80 | Submission Open

Keywords: artificial reproductive technologies; ART; mental health effect on ART; IVF; AI in reproductive medicine

(This special issue belongs to the Section Obstetrics & Gynecology)

Aortic Surgery: State of the Art and Future Directions

edited by

Dimos E. Karangelis

submission deadline 15 Jun 2026 | Viewed by 47 | Submission Open

Keywords: aortic surgery; aortic aneurysm; aortic dissection; aortic arch; biomaterials; endovascular approach; FET; TEVAR

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Diagnosis and Management of Erectile Dysfunction

edited by Maurizio De Rocco Ponce and

Giuseppe Grande

submission deadline 15 Jun 2026 | Viewed by 43 | Submission Open

Keywords: erectile dysfunction; clinical management; cardiovascular disease; penile prosthesis; personalized medicine; hipogonadism

(This special issue belongs to the Section Reproductive Medicine & Andrology)

Novel Diagnostic and Therapeutic Perspectives in Systemic Sclerosis

edited by Mislav Radić

submission deadline 15 Jun 2026 | Viewed by 36 | Submission Open

Keywords: systemic sclerosis; biomarkers; diagnosis; treatment; diagnostic imaging technique; early detection

(This special issue belongs to the Section Immunology & Rheumatology)

Gynecologic Oncology: Current Therapies and New Frontiers

edited by Laura Paleari and Mariangela Rutigliani

submission deadline 19 Jun 2026 | Viewed by 78 | Submission Open

Keywords: ovarian cancers; gynecological cancer; drug delivery; AI; screening; new therapies

(This special issue belongs to the Section Obstetrics & Gynecology)

Gynecologic and Obstetric Pathologies: From Birth to Menopause (Third Edition)

edited by

Panagiotis Christopoulos

submission deadline 20 Jun 2026 | 6 articles | Viewed by 20341 | Submission Open

Keywords: obstetrics; gynecology; pathology; pediatric and adolescent gynecology; menopause; urinary disorders; infertility; gynecologic oncology; maternal– fetal medicine; incontinence; menstruation; reproduction; polycystic ovarian syndrome; endometriosis; dysmenorrhea; assisted reproduction; IVF; laparoscopy; hysteroscopy; gynecologic robotic surgery; high-risk pregnancy

(This special issue belongs to the Section Obstetrics & Gynecology)

Advances in Trauma Care and Emergency Medicine

edited by

Lothar Andreas Schwarte

Patrick Schober

and

Georgios F. Giannakopoulos

submission deadline 20 Jun 2026 | 2 articles | Viewed by 13281 | Submission Open

Keywords: trauma; trauma care; emergency medicine; pre-hospital; emergency room; intensive care unit

(This special issue belongs to the Section Emergency Medicine)

Clinical Advances in Metabolic Dysfunction-Associated Steatotic Liver Disease

edited by Hirsh D. Trivedi

submission deadline 20 Jun 2026 | 5 articles | Viewed by 9720 | Submission Open

Keywords: metabolic dysfunction-associated steatotic liver disease; MASLD; non-alcoholic fatty liver disease; NAFLD; liver disease; liver fibrosis; metabolic syndrome

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Latest Advances in Orthodontics

edited by

Giuseppina Laganà

submission deadline 20 Jun 2026 | 3 articles | Viewed by 6862 | Submission Open

Keywords: digital treatment planning; clear aligners; skeletal anchorage; OSAS; artificial intelligence

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Advancements in Gait Rehabilitation: Innovative Approaches and Clinical Insights

edited by

Shinichi Watanabe

Nobuto Nakanishi

and

Yuki Iida

submission deadline 20 Jun 2026 | 4 articles | Viewed by 5805 | Submission Open

Keywords: sarcopenia; swallowing therapy; physical therapy; early mobilization; early rehabilitation; robot-assisted gait training; neurorehabilitation; wearable sensors

(This special issue belongs to the Section Clinical Rehabilitation)

Clinical Advances in Trauma and Orthopaedic Surgery

edited by Valerio Pace and Pierluigi Antinolfi

submission deadline 20 Jun 2026 | 3 articles | Viewed by 5239 | Submission Open

Keywords: orthopaedic surgery; hand/wrist surgery; tendon injury; ligament injury; artificial intelligence (AI); robotic surgery; orthopaedic injections; nerve injury

(This special issue belongs to the Section Orthopedics)

Evidence-Based Diagnosis and Clinical Management of Low Back Pain

edited by

William J. Hanney

and

Michael Masaracchio

submission deadline 20 Jun 2026 | 2 articles | Viewed by 5213 | Submission Open

Keywords: low back pain; classification systems; risk stratification; health services research; management strategies; timing and sequencing; prognosis; predictor; clinical decision making; primary care

(This special issue belongs to the Section Clinical Rehabilitation)

AI in Maternal Fetal Medicine and Perinatal Management

edited by Ariel Many

submission deadline 20 Jun 2026 | 2 articles | Viewed by 5115 | Submission Open

Keywords: maternal fetal medicine; high-risk pregnancy; perinatal management; artificial intelligence (AI) in obstetrics; fetal growth abnormalities; preterm labor prediction

(This special issue belongs to the Section Obstetrics & Gynecology)

Maternal–Fetal Medicine: Current Status, Challenges, and Future Directions

edited by Jessian Munoz

submission deadline 20 Jun 2026 | 3 articles | Viewed by 4323 | Submission Open

Keywords: maternal– fetal medicine; preterm delivery; preterm birth management; newborn; obstetrics; high-risk pregnancy; perinatal outcome; placenta accreta; fetal surgery

(This special issue belongs to the Section Obstetrics & Gynecology)

Advancements in Femtosecond Laser Applications

edited by Luca Schwarzenbacher, Eva Stifter and Philipp Roberts

submission deadline 20 Jun 2026 | 4 articles | Viewed by 4217 | Submission Open

Keywords: femtosecond laser; cataract surgery; DSAEK; DALK; femto-CAIRS; congenital cataract

(This special issue belongs to the Section Ophthalmology)

Advances in Clinical Approaches to Breast Cancer Diagnosis and Treatment

edited by

Lorenzo Scardina

submission deadline 20 Jun 2026 | 2 articles | Viewed by 4056 | Submission Open

Keywords: breast cancer; diagnosis; precision medicine; molecular profiling; targeted therapy; breast-conserving surgery; minimally invasive techniques; artificial intelligence; personalized medicine; radiation therapy

(This special issue belongs to the Section Oncology)

Ultrasound-Guided Biopsy of Gynecologic Tumors: Technique and Clinical Application

edited by

Athina A. Samara

and Alexandros Daponte

submission deadline 20 Jun 2026 | 1 articles | Viewed by 3343 | Submission Open

Keywords: ultrasound-guided biopsy; gynecologic tumors; ovarian cancer; biopsy technique; precision diagnosis; endometrial lesions

(This special issue belongs to the Section Obstetrics & Gynecology)

Updates on the Clinical Applications of Dental Restorative Materials

edited by

Vittorio Checchi

submission deadline 20 Jun 2026 | 1 articles | Viewed by 3266 | Submission Open

Keywords: restorative dentistry; restorations; adhesive dentistry; resin composites; ceramics; aesthetics; dental materials; direct restorations; indirect restorations; conservative dentistry; prosthetic dentistry; partial restorations; total restorations

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Antithrombotic Therapies for Acute Coronary Syndrome and Atrial Fibrillation

edited by

Mojca Božič Mijovski

submission deadline 20 Jun 2026 | 2 articles | Viewed by 3206 | Submission Open

Keywords: atrial fibrillation; acute coronary syndrome; antiplatelet agents; anticoagulants; thrombolysis; direct coagulation factor inhibitors; medical laboratory technology

(This special issue belongs to the Section Cardiology)

Innovations in the Clinical Management of Retinal Diseases: Emerging Therapies and Visual Rehabilitation

edited by

Francisco J. Povedano-Montero

submission deadline 20 Jun 2026 | 3 articles | Viewed by 2935 | Submission Open

Keywords: retinal diseases; macular degeneration; maculopathies; diabetic retinopathy; retinal vascular occlusions; retinitis pigmentosa

(This special issue belongs to the Section Ophthalmology)

Genitourinary Cancers: Clinical Advances and Practice Updates

edited by David Benjamin and Arash Rezazadeh Kalebasty

submission deadline 20 Jun 2026 | 3 articles | Viewed by 2806 | Submission Open

Keywords: rare tumors; genitourinary cancers; urachal cancer; penile cancer; testicular cancer; variant histology

(This special issue belongs to the Section Nephrology & Urology)

Advances in Diagnosis and Treatment of Urological Cancers

edited by Davide Campobasso,

Stefano Puliatti

and

Daniele Amparore

submission deadline 20 Jun 2026 | 2 articles | Viewed by 2541 | Submission Open

Keywords: prostate cancer; kidney cancer; urothelial carcinoma; testis cancer; mini-invasive surgery; precision surgery; target therapy; immunotherapy; nuclear medicine; artificial intelligence; augmented reality; biomarkers; prognostic factors and models; focal therapy; radiotherapy; imaging; genetics

(This special issue belongs to the Section Nephrology & Urology)

State-of-the-Art in Cardiac Surgery: Progress, Challenges and Opportunities

edited by Tomasz Plonek and Sleiman Sebastian Aboul-Hassan

submission deadline 20 Jun 2026 | 3 articles | Viewed by 2365 | Submission Open

Keywords: aorta ascendens; minimally invasive surgery; aortic arch surgery; off pump coronary surgery; arterial grafts

(This special issue belongs to the Section Cardiology)

Novel Aspects of Endocrine Care: From Patient-Centred Management of Endocrine Diseases to Guidelines Standards

edited by

Mara Carsote

and

Claudiu Nistor

submission deadline 20 Jun 2026 | 2 articles | Viewed by 2324 | Submission Open

Keywords: endocrine tumour; hormone; biomarker; neuroendocrine tumour; thyroidectomy; parathyroidectomy; bone; ad-renal gland; osteoporosis; pituitary gland; autoimmune; antibody; clinical study; computed tomography

(This special issue belongs to the Section Endocrinology & Metabolism)

New Insights in Maxillofacial Surgery

edited by

Izumi Asahina

submission deadline 20 Jun 2026 | 1 articles | Viewed by 2125 | Submission Open

Keywords: maxillofacial surgery; surgical techniques; imaging technologies; biomaterials; regenerative medicine

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Recent Advances in Transcatheter Aortic Valve Replacement: Second Edition

edited by

Anna Olasińska-Wiśniewska

and Maciej Dąbrowski

submission deadline 20 Jun 2026 | 2 articles | Viewed by 1886 | Submission Open

Keywords: aortic stenosis; transcatheter; bioprosthesis; TAVI; transcatheter aortic valve replacement

(This special issue belongs to the Section Cardiovascular Medicine)

Current Challenges and Perspectives in Liver Transplantation

edited by Bogdan Dorobanţu,

Umberto Cillo

and Waldo Concepcion

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1424 | Submission Open

Keywords: liver transplantation; liver surgery; liver cirrhosis; liver disease; alcoholic and non-alcoholic steatohepatitis; cholangiocarcinoma; hepatocellular carcinoma; auxiliary liver transplantation

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Current Perspectives and Innovations in Urogynecology

edited by Stavros Athanasiou

submission deadline 20 Jun 2026 | 2 articles | Viewed by 1191 | Submission Open

Keywords: urogynecology; pelvic organ prolapse; urinary incontinence; overactive bladder; pelvic floor surgery; reconstructive surgery; minimally invasive surgery; pelvic floor disorders; innovative surgical techniques; quality of life

(This special issue belongs to the Section Obstetrics & Gynecology)

New Perspectives in Maternal–Fetal Medicine

edited by Catalina de Paco-Matallana

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1167 | Submission Open

Keywords: maternal– fetal medicine; prenatal diagnostics; fetal therapy; precision medicine; neonatal outcomes; maternal health

(This special issue belongs to the Section Obstetrics & Gynecology)

Innovations in Psychosis and Schizophrenia: New Findings and Implications

edited by

Gabriele Nibbio

submission deadline 20 Jun 2026 | 2 articles | Viewed by 1145 | Submission Open

Keywords: schizophrenia; psychosis; psychopathology; neurobiology; assessment; pharmacological treatment; psychosocial interventions

(This special issue belongs to the Section Mental Health)

Cardiovascular Imaging: Diagnosis and Therapeutic Guidance in Clinical Practice

edited by

Stefano Figliozzi

submission deadline 20 Jun 2026 | 1 articles | Viewed by 938 | Submission Open

Keywords: cardiovascular magnetic resonance; cardiac imaging; T1 and T2 mapping; myocardial tissue characterization; late gadolinium enhancement; ischemic heart disease; cardiomyopathies; valvular heart disease; therapeutic guidance; precision medicine; mitral valve prolapse

(This special issue belongs to the Section Cardiology)

Therapies for Heart Failure: Clinical Updates and Perspectives

edited by Cristina Tudoran, Stela Iurciuc and Dragos Cozma

submission deadline 20 Jun 2026 | 1 articles | Viewed by 840 | Submission Open

Keywords: mechanisms of heart failure; new therapies for heart failure; chronic and acute heart failure; new approaches to managing heart failure patients; special populations; clinical outcome

(This special issue belongs to the Section Cardiology)

Clinical Advances in the Pharmacotherapy of Diabetes

edited by Jonathan Watanabe,

Joshua J. Neumiller

and

Cheyenne Frazier

submission deadline 20 Jun 2026 | 1 articles | Viewed by 767 | Submission Open

Keywords: diabetes; microvascular complications; macrovascular complications; diabetes technology; pharmacoepidemiology; care delivery; novel therapies

(This special issue belongs to the Section Pharmacology)

New Clinical Advances in Breast Reconstruction

edited by

Nobuyuki Mitsukawa

submission deadline 20 Jun 2026 | 1 articles | Viewed by 761 | Submission Open

Keywords: breast reconstruction; autologous (flap) reconstruction; implant-based reconstruction; microsurgery and perforator flaps; robotic surgery/endoscopic surgery; fat grafting (lipofilling); patient-reported outcomes; reconstructive surgical innovation

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

The New Era of Urological Surgery: Technology-Enhanced Clinical Outcomes

edited by

Razvan-George Rahota

and

Guillaume Ploussard

submission deadline 20 Jun 2026 | Viewed by 568 | Submission Open

Keywords: urology; surgery; robotic surgery; artificial intelligence; urological cancer

(This special issue belongs to the Section Nephrology & Urology)

Parkinson's Disease: Recent Advances in Diagnosis and Treatment

edited by

Mariachiara Sensi

and

Fabiana Colucci

submission deadline 20 Jun 2026 | 1 articles | Viewed by 564 | Submission Open

Keywords: Parkinson’ s disease; disease-modifying therapies; artificial intelligence; microbiome; alpha-synuclein; neuroimaging

(This special issue belongs to the Section Clinical Neurology)

Stroke in Patients with Atrial Fibrillation: Risk, Manifestation and Prevention

edited by

Iwona Gorczyca-Głowacka

submission deadline 20 Jun 2026 | 1 articles | Viewed by 542 | Submission Open

Keywords: anticoagulant treatment; atrial fibrillation; arrhythmia; personalized medicine; stroke

(This special issue belongs to the Section Cardiology)

Novel Insights into the Use of Artificial Intelligence in Clinical Medicine

edited by Sharon C. Kiang and Roger T. Tomihama

submission deadline 20 Jun 2026 | 1 articles | Viewed by 467 | Submission Open

Keywords: artificial intelligence; disease predictive models; wearable technology; surgical innovation; molecular targeting; big data science; machine learning; deep learning

Displaying special issue 1151-1200 on page 24 of 31.

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