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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Maternal–Fetal Medicine
edited by
submission deadline 20 Feb 2026 | 1 articles | Viewed by 784 | Submission Open
Keywords: maternal– fetal medicine; obstetric ultrasound; preterm birth; preeclampsia; pregnancy complications; artificial intelligence
(This special issue belongs to the Section Obstetrics & Gynecology)
Cancer Immunotherapy: Recent Advances and Clinical Challenges
edited by
submission deadline 20 Feb 2026 | 1 articles | Viewed by 768 | Submission Open
Keywords: immune checkpoint inhibitors; solid tumors; early-stage disease; metastatic disease; prognostic factors; biomarkers; resistance mechanisms
(This special issue belongs to the Section Oncology)
Age-Related Macular Degeneration: Challenges and Opportunities
edited by Deepayan Kar
submission deadline 20 Feb 2026 | 1 articles | Viewed by 763 | Submission Open
Keywords: age-related macular degeneration; imaging biomarkers; visual function testing; optical coherence tomography; anti-VEGF; complement; artificial intelligence
(This special issue belongs to the Section Ophthalmology)
Current Opinion in Dental Implant Surgery and Peri-Implant Disease
edited by and Giovanni Corrocher
submission deadline 20 Feb 2026 | 1 articles | Viewed by 741 | Submission Open
Keywords: dental implant surgery; dental implantology; peri-implant disease; oral surgery; dental implantology
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Diagnosis and Treatment of Gastrointestinal Malignancies
edited by and Gianmauro Numico
submission deadline 20 Feb 2026 | 1 articles | Viewed by 711 | Submission Open
Keywords: gastrointestinal cancers; immunotherapy; targeted therapy; chemotherapy; microsatellite instability; driver mutations
(This special issue belongs to the Section Oncology)
Novel Developments in Digestive Endoscopy
edited by
submission deadline 20 Feb 2026 | 1 articles | Viewed by 676 | Submission Open
Keywords: endoscopy for IBD; AI in endoscopy; therapeutic endoscopy; EUS; interventional EUS; AI in digestive endoscopy; quality in endoscopy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
New Insights into Orthodontic Treatment
edited by Federico Brugnami and Simonetta Meuli
submission deadline 20 Feb 2026 | 1 articles | Viewed by 634 | Submission Open
Keywords: digital orthodontics; clear aligners; artificial intelligence; digital superimpositions; cone beam computed tomography; growing patients; periodontal patients; maxillofacial surgery; long-term stability; prediction of orthodontic movements
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Treatment and Long-Term Outcome of Fracture
edited by , and Fabrizio Quattrini
submission deadline 20 Feb 2026 | 1 articles | Viewed by 633 | Submission Open
Keywords: traumatology; osteosynthesis; plating; nailing; osteosynthesis devices; surgical technique; approach
(This special issue belongs to the Section Orthopedics)
Rising Star: Advanced Physical Therapy and Expansion
edited by
submission deadline 20 Feb 2026 | 1 articles | Viewed by 630 | Submission Open
Keywords: physical therapy; digital therapeutic technology; geriatric diseases; pediatric; psychology of physical therapies; clinical approach
(This special issue belongs to the Section Clinical Rehabilitation)
Clinical Update on Cardiac Rehabilitation
edited by
submission deadline 20 Feb 2026 | Viewed by 608 | Submission Open
Keywords: cardiac rehabilitation; cardiovascular disease; physiotherapy; interprofessional intervention; exercise training; nutritional counseling; psychosocial support; secondary prevention; rehabilitation modalities; rehabilitation tools
(This special issue belongs to the Section Clinical Rehabilitation)
Current Challenges and Innovations in Emergency Medicine: From Prehospital Care to Critical Decision-Making in the Emergency Department
edited by , Barbara P. Fyntanidou and
submission deadline 20 Feb 2026 | 1 articles | Viewed by 574 | Submission Open
Keywords: emergency medicine; prehospital care; triage strategies; acute care; point-of-care diagnostics; artificial intelligence; telemedicine; emergency department; patient flow; healthcare systems; burnout in emergency care
(This special issue belongs to the Section Emergency Medicine)
Clinical Applications of Cardiac Imaging: 2nd Edition
edited by Maria Concetta Pastore
submission deadline 20 Feb 2026 | 1 articles | Viewed by 487 | Submission Open
Keywords: cardiac imaging; echocardiography; magnetic resonance imaging; computed tomography; nuclear imaging; heart failure; valvular heart disease; congenital heart disease
(This special issue belongs to the Section Cardiology)
State of the Art in Interventional Cardiology
edited by Antonios Karanasos
submission deadline 20 Feb 2026 | Viewed by 454 | Submission Open
Keywords: interventional cardiology; intravascular imaging; structural interventions; TAVI; vascular access; percutaneous coronary intervention; coronary stenting; cardiovascular diseases
(This special issue belongs to the Section Cardiology)
Novel Research in Pediatric Dentistry: 2nd Edition
edited by Christian Hirsch and
submission deadline 20 Feb 2026 | 1 articles | Viewed by 443 | Submission Open
Keywords: early childhood caries; primary teeth; caries prevention; caries treatment; behavioral management; molar incisor hypomineralization; dental trauma; sedation; oral health-related quality of life
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Cardiac Anesthesia: Current Research and Future Prospects
edited by and Lorenzo Stephan Cesare Grazioli
submission deadline 20 Feb 2026 | Viewed by 353 | Submission Open
Keywords: cardiac anesthesia; cardiac surgery; echocardiography; interventional cardiology; anesthesia; cardiology
(This special issue belongs to the Section Anesthesiology)
Current and Emerging Treatment Options in Atrial Fibrillation: 2nd Edition submission deadline 20 Feb 2026 | Viewed by 324 | Submission Open
Keywords: atrial fibrillation; left atrial appendage closure; ablation techniques; personalized medicine in AF treatment; cardioversion methods
(This special issue belongs to the Section Cardiology)
Disease Modifying Activity in Psoriasis and Atopic Dermatitis submission deadline 20 Feb 2026 | Viewed by 288 | Submission Open
Keywords: atopic dermatitis; biologics; psoriasis; disease-modifying treatment; small molecules; type 2 inflammation
(This special issue belongs to the Section Dermatology)
Novel Insights for Imaging and Therapy in Maternal and Fetal Medicine
edited by Xin Kang
submission deadline 20 Feb 2026 | Viewed by 256 | Submission Open
Keywords: prenatal imaging; prenatal diagnosis; fetal virtual autopsy; preeclampsia; macrosomia; preterm birth; pelvic floor
(This special issue belongs to the Section Obstetrics & Gynecology)
Endocrine Disorders in Children: 2nd Edition submission deadline 20 Feb 2026 | Viewed by 172 | Submission Open
Keywords: endocrinology; pediatrics; hormones; genetics; growth; nutrition; development  ; adolescence  ; prevention
(This special issue belongs to the Section Clinical Pediatrics)
Minimally Invasive Surgery for Gastrointestinal Disorder submission deadline 20 Feb 2026 | Viewed by 169 | Submission Open
Keywords: minimally invasive surgery; gastrointestinal disorder; laparoscopy; robotic surgery; colorectal surgery; gastric surgery; endoscopic technique; oncological outcomes; surgical innovation
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Hypercholesterolemia: Update on Treatment Approaches and Outcomes
edited by and Lucia Barbieri
submission deadline 20 Feb 2026 | Viewed by 155 | Submission Open
Keywords: hypercholesterolemia; dyslipidemia; atherosclerosis; cardiovascular risk; LDL; HDL; lipoprotein(a)
(This special issue belongs to the Section Cardiovascular Medicine)
Recent Advances and Future Perspectives on Spinal Surgeries
edited by
submission deadline 20 Feb 2026 | Viewed by 153 | Submission Open
Keywords: minimally invasive spine procedures; robotic-assisted spine surgery; image-guided navigation; spinal implants and biomaterials; artificial intelligence in spinal care; regenerative spine therapies; clinical outcomes in spine surgery; future trends in spinal interventions
(This special issue belongs to the Section Orthopedics)
Advances in the Diagnosis and Management of Atherosclerosis submission deadline 20 Feb 2026 | Viewed by 151 | Submission Open
Keywords: atherosclerosis; cardiovascular disease; coronary artery disease; endothelial function; acute coronary syndromes
(This special issue belongs to the Section Cardiology)
Maxillofacial Surgery in the Modern Era: Surgical Advances and Clinical Innovation submission deadline 20 Feb 2026 | Viewed by 149 | Submission Open
Keywords: maxillofacial surgery; oral surgery; craniofacial surgery; plastic surgery; bone
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Progress and Innovation in the Clinical Management of Psychosis
edited by
submission deadline 20 Feb 2026 | Viewed by 147 | Submission Open
Keywords: psychosis; schizophrenia; clinical interventions; neurobiological mechanisms; early intervention
(This special issue belongs to the Section Mental Health)
Advances and Innovations in Radiology: From Contrast-Enhanced Mammography to Artificial Intelligence and Beyond
edited by
submission deadline 20 Feb 2026 | Viewed by 146 | Submission Open
Keywords: contrast-enhanced mammography (CEM); artificial intelligence; radiomics; diagnostic imaging innovations; inter-ventional radiology
(This special issue belongs to the Section Nuclear Medicine & Radiology)
New Insights in Cognitive Aging and Mild Cognitive Impairment submission deadline 20 Feb 2026 | 1 articles | Viewed by 140 | Submission Open
Keywords: cognitive aging; mild cognitive impairment; normative aging; neuropsychological assessment; diagnosis; gerontology; prevention; intervention; multidisciplinary approach; measurement
(This special issue belongs to the Section Geriatric Medicine)
Innovations and Challenges in the Burden and Rehabilitation of Musculoskeletal Disorders submission deadline 20 Feb 2026 | Viewed by 138 | Submission Open
Keywords: musculoskeletal diseases; rehabilitation; physical therapy modalities; telemedicine; mobile applications; health information technology; patient-centered care; quality of life; health care innovation
(This special issue belongs to the Section Clinical Rehabilitation)
Myocarditis and Pericarditis: Clinical Advances and Current Challenges submission deadline 20 Feb 2026 | Viewed by 135 | Submission Open
Keywords: pericarditis; myocarditis; pericardial effusion; cardiac tamponade; interleukin-1 inhibitors; pericardium
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Updates on Acromegaly
edited by , Jowita Halupczok-Żyła, Aleksandra Gilis-Januszewska and Przemysław Witek
submission deadline 20 Feb 2026 | Viewed by 128 | Submission Open
Keywords: acromegaly; GH; IGH-1; growth hormone-secreting pituitary adenoma; pituitary adenoma
(This special issue belongs to the Section Endocrinology & Metabolism)
Rheumatoid Arthritis: Insights into Appropriate Diagnosis, Treatment and Management
edited by
submission deadline 20 Feb 2026 | Viewed by 126 | Submission Open
Keywords: rheumatoid arthritis; precision medicine; difficult-to-treat rheumatoid arthritis; late-onset rheumatoid arthritis; ageing society; comorbidities
(This special issue belongs to the Section Immunology & Rheumatology)
Advances in Posttraumatic Stress Disorder (PTSD): Clinical Update
edited by An-Fu Hsiao and
submission deadline 20 Feb 2026 | Viewed by 112 | Submission Open
Keywords: PTSD; stellate ganglion block; transcranial magnetic stimulations; neurobiology; trauma disorders; mind– body medicine; psychophysiology
(This special issue belongs to the Section Mental Health)
Diagnosis and Treatment of Cardiovascular Diseases in the Elderly submission deadline 20 Feb 2026 | Viewed by 112 | Submission Open
Keywords: cardiovascular diseases; elderly population; diagnosis and management; age-related pathophysiology; frailty and cognitive impairment
(This special issue belongs to the Section Geriatric Medicine)
Metastatic Colorectal Cancer Beyond Second-Line Treatment
edited by Jacopo Giuliani
submission deadline 20 Feb 2026 | Viewed by 111 | Submission Open
Keywords: metastatic colorectal cancer; subsequent lines; chemotherapy; targeted agents; radiotherapy; local therapy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Advances in Meningioma Surgery
edited by
submission deadline 20 Feb 2026 | Viewed by 104 | Submission Open
Keywords: meningioma; cranial neurosurgery; brain tumors; skull base surgery; endoscopic neurosurgery; intraoperative techniques; surgical outcomes; minimally invasive neurosurgery; perioperative management; clinical meningioma research
(This special issue belongs to the Section Clinical Neurology)
Endoscopic Imaging for the Diagnosis and Treatment of Gastrointestinal Diseases
edited by Mariana Jinga and
submission deadline 20 Feb 2026 | Viewed by 99 | Submission Open
Keywords: endoscopy; endoscopic ultrasound; endoscopic retrograde cholangiopancreatography; artificial intelligence; diagnosis; therapy; decision making; endobiopsy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Bleeding and Thrombotic Complications in Patients with Premalignant Hematologic Conditions: Diagnostic and Therapeutic Challenges
edited by Vasiliki Gkalea and Despina Fotiou
submission deadline 20 Feb 2026 | Viewed by 98 | Submission Open
Keywords: bleeding; thrombosis; hematologic malignancies; premalignant hematologic conditions; clonal hematopoiesis of indeterminate potential (CHIP); clonal cytopenias of undetermined significance (CCUS); monoclonal gammopathy of undetermined significance (MGUS); monoclonal B-cell lymphocytosis (MBL); monoclonal gammopathy of thrombotic significance (MGTS); VITT-like MGTS
(This special issue belongs to the Section Hematology)
Optimizing Rehabilitation in Kidney Disease
edited by Henry H. L. Wu and Rajkumar Chinnadurai
submission deadline 20 Feb 2026 | Viewed by 96 | Submission Open
Keywords: chronic kidney disease; renal rehabilitation; exercise intervention; nutrition; multidisciplinary; frailty; physical conditioning
(This special issue belongs to the Section Clinical Rehabilitation)
Advances in the Personalized Management of Chronic Obstructive Pulmonary Disease (COPD)
edited by and Georgios Hillas
submission deadline 20 Feb 2026 | Viewed by 95 | Submission Open
Keywords: artificial intelligence; biologics; biomarkers; diagnostics; oscillometry; COPD pharmacotherapy; imaging
(This special issue belongs to the Section Respiratory Medicine)
Clinical Advances in Sepsis and Septic Shock
edited by and Lorenzo Ghiadoni
submission deadline 20 Feb 2026 | Viewed by 89 | Submission Open
Keywords: sepsis-induced coagulopathy; endothelial dysfunction in sepsis; fluid balance in sepsis
(This special issue belongs to the Section Emergency Medicine)
New Insights into Management of Chronic Rhinosinusitis submission deadline 20 Feb 2026 | Viewed by 79 | Submission Open
Keywords: chronic rhinosinusitis; management; surgery; minimally invasive surgery; surgical oncology; cancer surgery; skull base surgery; hoarseness; laryngeal neoplasms; laryngoscopy; general surgery; X-ray computed tomography
(This special issue belongs to the Section Otolaryngology)
Recent Advances in Gynecologic Surgery
edited by Adam Ostrzenski
submission deadline 20 Feb 2026 | Viewed by 68 | Submission Open
Keywords: gynecologic surgery; pelvic reconstruction surgery; female stress urinary incontinence surgery; cosmetic gynecology surgery; surgical meshes slings; native tissue
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Advances in Head and Neck Cancer Diagnostics and Treatment
edited by and Alice L. Tang
submission deadline 20 Feb 2026 | Viewed by 66 | Submission Open
Keywords: head and neck; reconstruction; free flap; surgical margin; biomarker; human papillomavirus (HPV); extranodal extension; immunotherapy; virtual surgical planning
(This special issue belongs to the Section Otolaryngology)
Mental Disorders, Cognitive Impairment and Dementia Among Older Adults submission deadline 21 Feb 2026 | 3 articles | Viewed by 4056 | Submission Open
Keywords: mental disorders; cognitive decline; dementia; older adults; mental health; exercise; physical function
(This special issue belongs to the Section Geriatric Medicine)
Advances in Plastic and Reconstructive and Aesthetic Surgery of Face, Breast and Body
edited by
submission deadline 24 Feb 2026 | 3 articles | Viewed by 5439 | Submission Open
Keywords: reconstructive surgery; academic plastic surgery; research; social media in plastic surgery; breast surgery
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Current and Emerging Treatment Options for Aortic Aneurysms
edited by Spyros Ioannis Papadoulas and
submission deadline 24 Feb 2026 | 1 articles | Viewed by 365 | Submission Open
Keywords: thoracic aortic aneurysms; abdominal aortic aneurysm; vascular surgery; cardiac surgery; treatment
(This special issue belongs to the Section Vascular Medicine)
Acute Respiratory Failure: Innovations and Clinical Insights
edited by
submission deadline 25 Feb 2026 | 3 articles | Viewed by 20929 | Submission Open
Keywords: ARF; mechanical ventilation; VILI; PSILI; NIV; HFNO; weaning; EIT; lung US
(This special issue belongs to the Section Intensive Care)
Interventional Pulmonology: Advances and Future Directions
edited by Martina Ferioli and Piero Candoli
submission deadline 25 Feb 2026 | 7 articles | Viewed by 11883 | Submission Open
Keywords: interventional pulmonology; lung nodule; lung cancer; diagnosis; bronchoscopy; rigid bronchoscopy; airway stent; airway stenosis; mediastinal staging
(This special issue belongs to the Section Respiratory Medicine)
(Recent Advances) Treating Psychiatry Disorders in Children and Adolescents: From Theory to Practice: 2nd Edition submission deadline 25 Feb 2026 | 5 articles | Viewed by 9687 | Submission Open
Keywords: intervention program; youth psychopathology; internalizing disorders; externalizing disorders; psychiatric disorders
(This special issue belongs to the Section Mental Health)
Advancing Pediatric Sports Medicine: Insights and Innovations
edited by Brian C. Lau
submission deadline 25 Feb 2026 | 4 articles | Viewed by 7678 | Submission Open
Keywords: sport surgery; patellar instability; early sport specialization; triplane fractures; pediatric sports medicine; orthopedic surgery; access to care; arthroscopic
(This special issue belongs to the Section Orthopedics)
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