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JCM
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Novel Research in Pediatric Dentistry: 2nd Edition
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Novel Research in Pediatric Dentistry: 2nd Edition

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Dentistry, Oral Surgery and Oral Medicine".

Deadline for manuscript submissions: 20 February 2026 | Viewed by 399

Special Issue Editors

Prof. Dr. Christian Hirsch

E-Mail Website
Guest Editor
Department of Pediatric Dentistry, University of Leipzig, Leipzig, Germany
Interests: temporomandibular disorders and bruxism in children and adolescents; oral health-related quality of life (OHRQoL) in children and adolescents
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Katrin Bekes

E-Mail Website
Guest Editor
Department of Pediatric Dentistry, Medical University of Vienna, Sensengasse 2a, A-1090 Vienna, Austria
Interests: pediatric dentistry; conservative dentistry; oral health related quality of life
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

It is my pleasure to invite you to contribute to the Special Issue entitled “Novel Research in Pediatric Dentistry: 2nd Edition”. We published 9 papers in the first volume. For more details, please visit: https://www.mdpi.com/journal/jcm/special_issues/XOV707XB74.

Pediatric dentistry provides preventive and therapeutic oral health care for infants and children throughout adolescence, together with special health care needs. Early childhood caries (ECCs) and molar incisor hypomineralization (MIH) represent a major challenge at the moment. Despite improvements in efforts regarding dental health education, ECCs is still a highly prevalent disease affecting millions of preschool children worldwide. Moreover, MIH—a common developmental dental condition—is increasingly recognized.

This Special Issue aims to focus on novel research in pediatric dentistry. Topics to be covered include the prevention and management of oral childhood diseases, as well as the impact on OHRQoL. We invite relevant original research, systematic reviews, meta-analyses, and short communications covering the above-mentioned topics.

Prof. Dr. Christian Hirsch
Prof. Dr. Katrin Bekes
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • early childhood caries
  • primary teeth
  • caries prevention
  • caries treatment
  • behavioral management
  • molar incisor hypomineralization
  • dental trauma
  • sedation
  • oral health-related quality of life

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Published Papers (1 paper)

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Research

9 pages, 218 KB  
Article
Tooth Eruption and Microbial Correlation in Pediatric Appendicitis: An Exploratory Case–Control Study
by Wieland Elger, Carlotta Blod, Sara Schülin, Christian Hirsch, Martin Lacher and Steffi Mayer
J. Clin. Med. 2025, 14(20), 7372; https://doi.org/10.3390/jcm14207372 - 18 Oct 2025
Viewed by 225
Abstract
Background/Objectives: The oral cavity has been discussed as a possible reservoir for pathogens involved in pediatric appendicitis. In a previous study, microbial similarities between oral and appendix samples were observed, but clinical dental findings showed no significant associations. The present study aimed [...] Read more.
Background/Objectives: The oral cavity has been discussed as a possible reservoir for pathogens involved in pediatric appendicitis. In a previous study, microbial similarities between oral and appendix samples were observed, but clinical dental findings showed no significant associations. The present study aimed to (1) perform a more detailed analysis of dental variables—such as eruption status, caries indices, oral hygiene behavior, and the Periodontal Screening Index (PSI)—to identify potential overlooked associations with appendicitis, and (2) compare two oral sampling sites (buccal mucosa and dental sulcus) in terms of their correlation with appendix microbiota. Methods: This secondary analysis used previously collected clinical and microbiological data from 36 children who had undergone appendectomy or elective surgery. Quantitative PCR (qPCR) was used to assess bacterial mRNA levels in appendix, buccal mucosa, and sulcus samples. Dental variables were derived from standardized clinical examinations performed at the time of surgery. Results: No significant group differences were observed in caries indices, PSI, or oral hygiene behavior. However, patients with appendicitis had a significantly higher number of erupting teeth compared to controls (3.82 vs. 1.68; p = 0.021). Bacterial mRNA levels did not differ notably between oral sites, and neither showed stronger correspondence with appendix samples; notably, sulcus swabs were not obtained from erupting teeth, limiting the ability to test a site-specific eruption mechanism. Conclusions: Tooth eruption may be associated with appendicitis, although this remains speculative and requires confirmation in larger studies. Full article
(This article belongs to the Special Issue Novel Research in Pediatric Dentistry: 2nd Edition)
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