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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Updates on Rheumatoid Arthritis: 2nd Edition
edited by Francesca Bandinelli
submission deadline 22 May 2026 | 1 articles | Viewed by 1635 | Submission Open
Keywords: rheumatoid arthritis; rheumatology; treatment; diagnosis; biomarkers; rheumatic disease
(This special issue belongs to the Section Immunology & Rheumatology)
Takotsubo Syndrome: Insights into Pathophysiology, Diagnosis, and Management submission deadline 22 May 2026 | Viewed by 294 | Submission Open
Keywords: takotsubo syndrome; stress cardiomyopathy; acute heart failure; cardiac imaging; catecholamine surge; myocardial dysfunction; echocardiography; biomarker discovery; cardiovascular risk; clinical management
(This special issue belongs to the Section Cardiology)
Role of Platelet in Inflammation, Infection, and Immune Response submission deadline 22 May 2026 | Viewed by 213 | Submission Open
Keywords: platelets; platelet count; dual antiplatelet therapy; inflammation; thrombosis; inflammation; hemostasis; immune response
(This special issue belongs to the Section Hematology)
Clinical Pharmacology: Adverse Drug Reactions
edited by and Ivana Mudnić
submission deadline 25 May 2026 | 6 articles | Viewed by 26421 | Submission Open
Keywords: pharmacology; adverse drug reactions; drug interactions; pharmacovigilance; drug safety
(This special issue belongs to the Section Pharmacology)
Neurovascular Diseases: Clinical Advances and Challenges
edited by , Silky Chotai, Alessandro Di Rienzo and Joham Choque-Velasquez
submission deadline 25 May 2026 | 12 articles | Viewed by 24473 | Submission Open
Keywords: neurovascular diseases; ischemic stroke; hemorrhagic stroke; aneurysms; vascular malformations; diagnostic imaging; minimally invasive approaches; surgical techniques; endovascular interventions; treatment algorithms
(This special issue belongs to the Section Clinical Neurology)
Ventilation in Critical Care Medicine: 2nd Edition
edited by Gianluca Zani
submission deadline 25 May 2026 | 3 articles | Viewed by 16122 | Submission Open
Keywords: invasive ventilation; non-invasive ventilation; acute respiratory failure; best PEEP; respiratory weaning; respiratory mechanics; ventilation and perfusion; personalized ventilation
(This special issue belongs to the Section Intensive Care)
The Association Between Sleep Disorders and Metabolic and Mental Health submission deadline 25 May 2026 | 7 articles | Viewed by 13091 | Submission Open
Keywords: sleep medicine; sleep apnea; hypoxia; metabolism; mental health; women’ s health
(This special issue belongs to the Section Mental Health)
Maxillo-Facial Surgery: New Insights and Technologies in Head and Neck
edited by Federica Ruggiero
submission deadline 25 May 2026 | 6 articles | Viewed by 11952 | Submission Open
Keywords: oral and maxilla-facial surgery; orthognathic surgery; cranio-facial surgery; head and neck surgery; augmented reality; navigation; finite element modeling; virtual surgical planning; patient-specific implants
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Preventive, Diagnostic and Therapeutic Strategies for Abdominal Surgery Complications (Second Edition)
edited by
submission deadline 25 May 2026 | 5 articles | Viewed by 9561 | Submission Open
Keywords: complications; diagnosis; treatment; management; morbidity; abdomen; abdominal surgery; outcome; postoperative
(This special issue belongs to the Section General Surgery)
Oral and Maxillofacial Surgery: Diagnosis, Management and Future Opportunities
edited by
submission deadline 25 May 2026 | 5 articles | Viewed by 8640 | Submission Open
Keywords: head and neck oncology; free flaps; oral surgery; malformative surgery; traumatology; endoscopy; preprosthetic surgery; reconstructive surgery; vascular malformations; osteonecrosis
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Clinical Diagnosis and Management of Vestibular Disorders
edited by , Mario Habek and
submission deadline 25 May 2026 | 7 articles | Viewed by 8006 | Submission Open
Keywords: vertigo; dizziness; epidemiology; genetics; diagnostics; management
(This special issue belongs to the Section Otolaryngology)
Clinical Utility of Optical Coherence Tomography in Ophthalmology: 2nd Edition submission deadline 25 May 2026 | 4 articles | Viewed by 7323 | Submission Open
Keywords: optical coherence tomography; ophthalmology; intraoperative OCT; en face OCT; wide-field OCT; retinal diseases; glaucoma; cornea; strabismus; cataract
(This special issue belongs to the Section Ophthalmology)
Future Opportunities in Thoracic Surgery: The Cutting Edge: 2nd Edition
edited by
submission deadline 25 May 2026 | 2 articles | Viewed by 5920 | Submission Open
Keywords: surgical resection; immunotherapy; target therapy; thoracic surgery; thoracic oncology; lung cancer
(This special issue belongs to the Section Respiratory Medicine)
Assisted Reproductive Technology and Infertility Treatment: Current Updates and Perspectives—2nd Edition
edited by Nikos Nikolettos and
submission deadline 25 May 2026 | 3 articles | Viewed by 4133 | Submission Open
Keywords: assisted reproduction technology (ART); infertility; treatment; reproduction; IVF
(This special issue belongs to the Section Reproductive Medicine & Andrology)
Novel Insights into the Diagnosis and Management of Inflammatory Bowel Disease (IBD)
edited by
submission deadline 25 May 2026 | 4 articles | Viewed by 4111 | Submission Open
Keywords: inflammatory bowel disease; non-invasive biomarkers; abdominal ultrasonography; colonoscopy; biologic therapy; small molecules; mucosal healing; brain-gut axis; dysbiosis; colorectal dysplasia
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
The Rebirth of Ventral Skull Base Surgery through Multiportal Approaches: Endonasal, Transorbital, Transmaxillary and Transoral Routes
edited by Matteo de Notaris and Francesco Corrivetti
submission deadline 25 May 2026 | 3 articles | Viewed by 2769 | Submission Open
Keywords: skull base surgery; neuroendoscopy; neuroanatomy; multiportal approaches; technical advancements
(This special issue belongs to the Section Clinical Neurology)
Clinical Highlights in Uveal Melanoma
edited by Tomasz Chorągiewicz and
submission deadline 25 May 2026 | 1 articles | Viewed by 2341 | Submission Open
Keywords: choroidal melanoma; uveal melanoma; radiotherapy; enucleation; brachytherapy
(This special issue belongs to the Section Ophthalmology)
Clinical Advances of Breast Surgery and Reconstruction
edited by and Emanuele Cigna
submission deadline 25 May 2026 | 1 articles | Viewed by 2160 | Submission Open
Keywords: breast reconstruction; autologous breast reconstruction; implant-based breast reconstruction; DIEP; LICAP; breast implant infection
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Interstitial Lung Disease Secondary to Autoimmune Disorders: Recent Advances and Novel Perspectives
edited by , and Francesco Ferro
submission deadline 25 May 2026 | 1 articles | Viewed by 2003 | Submission Open
Keywords: interstitial lung disease; lung involvement; connective tissue diseases; rheumatoid arthritis; systemic vasculitis; radiomics; lung ultrasound; biomarkers; pathogenetic immunological pathways; therapeutic targets
(This special issue belongs to the Section Respiratory Medicine)
Advances in the Clinical Management of Perioperative Anesthesia: 2nd Edition
edited by Alessia Mattei, Rita Cataldo and
submission deadline 25 May 2026 | 3 articles | Viewed by 1936 | Submission Open
Keywords: perioperative outcomes (surgical; anesthetic; medical); evidence-based care; perioperative guidelines and consensus statements; preoperative evaluation and risk scores; preoperative testing; surgical optimization and enhanced surgical recovery programs; intensive care unit
(This special issue belongs to the Section Anesthesiology)
Current Clinical Advances in Urinary Incontinence
edited by Adolf Lukanovic, David Lukanović and Mija Blaganje
submission deadline 25 May 2026 | 2 articles | Viewed by 1717 | Submission Open
Keywords: female urinary incontinence; stress urinary incontinence; overactive bladder; diagnosis; prevention; conservative treatment; minimally invasive treatment; surgery; mid-urethral sling; new approach; energy-based devices
(This special issue belongs to the Section Nephrology & Urology)
Innovative Technologies and Approaches in Eye Disease Management and Refractive Surgery
edited by
submission deadline 25 May 2026 | 1 articles | Viewed by 1519 | Submission Open
Keywords: multifocal intraocular lenses; femtosecond lasers; artificial intelligence; imaging; eye surgery; refractive surgery
(This special issue belongs to the Section Ophthalmology)
Diabetic Foot: Emerging Prevention Strategies and Epidemiology submission deadline 25 May 2026 | 2 articles | Viewed by 1502 | Submission Open
Keywords: diabetic foot; foot clinics; epidemiology; prevention; screening; amputation; podiatry
(This special issue belongs to the Section Endocrinology & Metabolism)
Autoimmune-Induced Alopecia and Emerging Therapies in Hair Loss—2nd Edition
edited by David Saceda-Corralo
submission deadline 25 May 2026 | 2 articles | Viewed by 1303 | Submission Open
Keywords: autoimmune-induced alopecia; alopecia areata; cicatricial alopecia; occurs; hair loss; frontal fibrosing alopecia
(This special issue belongs to the Section Dermatology)
Clinical Updates in Reproductive Endocrinology: 2nd Edition
edited by Iwona Bojar and
submission deadline 25 May 2026 | 1 articles | Viewed by 1264 | Submission Open
Keywords: reproductive endocrinology; endocrine diseases in pregnancy; infertility; endocrine diagnostics in infertility; long-term consequences of endocrine disorders; therapy for endocrine disorders
(This special issue belongs to the Section Obstetrics & Gynecology)
Advances in Maxillofacial Surgery—Historical and Future Perspectives and Controversies submission deadline 25 May 2026 | 1 articles | Viewed by 1232 | Submission Open
Keywords: oral oncology; facial skeleton; oral cavity; surgical approaches; head and neck; parotid tumors; jaw cysts and tumors; bone healing; patient-specific solutions; surgery planning; artificial intelligence; soft tissues; cancers and tumors of the oral cavity; microsurgery perspectives; open surgery; endoscopic surgery; trauma surgery; facial traumatology; bone and soft tissues healing after trauma; jaw deformities; orthognathic surgery today and tomorrow
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Approaches and Challenges in Oral Rehabilitation
edited by and Takayuki Kosaka
submission deadline 25 May 2026 | 1 articles | Viewed by 1176 | Submission Open
Keywords: oral rehabilitation; oral health; systemic health; dental innovation; neuroplasticity
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Interstitial Lung Diseases: New Treatments Based on Treatable Traits
edited by Francesco Amati
submission deadline 25 May 2026 | 1 articles | Viewed by 634 | Submission Open
Keywords: interstitial lung diseases; progressive pulmonary fibrosis; phenotypes; endotypes; treatment; precision medicine
(This special issue belongs to the Section Respiratory Medicine)
New Insights in Paediatric Endocrinology
edited by
submission deadline 25 May 2026 | 1 articles | Viewed by 631 | Submission Open
Keywords: endocrinology; pediatrics; hormones; therapy and treatment; adolescents; newborns
(This special issue belongs to the Section Clinical Pediatrics)
Transcatheter Aortic Valve Implantation- Clinical Management and Future Challenges
edited by Mohamed Farag
submission deadline 25 May 2026 | 1 articles | Viewed by 551 | Submission Open
Keywords: transcatheter aortic valve implantation; TAVI; bicuspid aortic valve; small annulus; prosthesis– patient mismatch; coronary reaccess; valve-in-valve TAVI; leaflet modification
(This special issue belongs to the Section Cardiovascular Medicine)
Anemia: Clinical Updates in Diagnosis, Management, and Treatment submission deadline 25 May 2026 | 1 articles | Viewed by 515 | Submission Open
Keywords: anemia; diagnostic tools; hematology; artificial intelligence; targeted therapy; hereditary hemolytic anemia
(This special issue belongs to the Section Hematology)
Multiple Sclerosis and Demyelinating Disease: Clinical Treatment and Management
edited by Sotirios Giannopoulos
submission deadline 25 May 2026 | 1 articles | Viewed by 488 | Submission Open
Keywords: multiple sclerosis; demyelinating disease; comorbidities; disease modifying treatments; neuromuscular disorder; myasthenia gravis
(This special issue belongs to the Section Clinical Neurology)
New Advances in Congenital Heart Disease submission deadline 25 May 2026 | 1 articles | Viewed by 446 | Submission Open
Keywords: congenital heart disease; pediatric cardiology; adult congenital heart disease; cardiac surgery; interventional cardiology; long-term outcomes; cardiac imaging
(This special issue belongs to the Section Cardiology)
Current Perspectives on the Clinical Management of Respiratory Diseases submission deadline 25 May 2026 | 1 articles | Viewed by 344 | Submission Open
Keywords: COPD; acute exacerbations; biomarkers; clinical trials; bronchiectasis; respiratory infections
(This special issue belongs to the Section Respiratory Medicine)
Anesthesia and Perioperative Management of Organ Transplants
edited by and Ji-Hye Kwon
submission deadline 25 May 2026 | Viewed by 315 | Submission Open
Keywords: liver transplantation; coagulation; reperfusion syndrome; perioperative evaluation; coronary artery disease; CDC; DBD; living donor liver transplant; pulmonary evaluation; hepatorenal syndrome; portopulmonary hypertension
(This special issue belongs to the Section Anesthesiology)
Non-Small Cell Lung Cancer (NSCLC): Recent Advances in Clinical Diagnosis and Treatment
edited by
submission deadline 25 May 2026 | 1 articles | Viewed by 270 | Submission Open
Keywords: novel screening tool; cancer biomarkers; predictive marker of immunotherapy; targeted therapy; radiotherapy; non-small cell lung cancer
(This special issue belongs to the Section Oncology)
Advances in Ablation Therapy for Atrial Fibrillation: Innovations and Clinical Applications
edited by Ioanna Koniari
submission deadline 25 May 2026 | Viewed by 216 | Submission Open
Keywords: atrial fibrillation; ablation; PFA; PVI; non-thermal energy; mapping system
(This special issue belongs to the Section Cardiology)
High-Risk Neuroblastoma and Rhabdoid Tumors: New Clinical Insights and Challenges (Second Edition)
edited by and Johannes Hubertus Schulte
submission deadline 25 May 2026 | Viewed by 169 | Submission Open
Keywords: neuroblastoma; rhabdoid tumor; autologous stem cell transplantation; allogeneic stem cell transplantation immunotherapy; anti-GD2 antibody; targeted therapy; CAR T-cells
(This special issue belongs to the Section Oncology)
Surgical Innovation and Clinical Outcomes in Plastic and Reconstructive Surgery
edited by Pari Naz Mohanna and Ayush Kapila
submission deadline 25 May 2026 | Viewed by 96 | Submission Open
Keywords: plastic and reconstructive surgery; microsurgery; breast reconstruction; surgical innovation; novel flap techniques
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Clinical Advances and Challenges in Vascular and Endovascular Medicine: 2nd Edition
edited by
submission deadline 25 May 2026 | Viewed by 85 | Submission Open
Keywords: vascular and endovascular medicine; minimally invasive cardiovascular surgery; vascular diseases; endovascular technologies
(This special issue belongs to the Section Vascular Medicine)
Advances in the Clinical Management of Diabetic Retinopathy
edited by
submission deadline 25 May 2026 | Viewed by 85 | Submission Open
Keywords: retinal imaging; clinical outcomes; optical coherence tomography (OCT); vitrectomy; blood flow
(This special issue belongs to the Section Ophthalmology)
Clinical Advances in Personalized Psychiatry
edited by
submission deadline 25 May 2026 | Viewed by 84 | Submission Open
Keywords: personalized psychiatry; biomarkers; predictive modeling; precision diagnosis; neuroimaging biomarkers; effective treatments
(This special issue belongs to the Section Mental Health)
An Update to Trends and Strategies in Vascular and Endovascular Surgery
edited by Karin Pfister and Fiona Rohlffs
submission deadline 25 May 2026 | Viewed by 82 | Submission Open
Keywords: vascular surgery; endovascular surgery; carotid endarterectomy; peripheral vascular diseases; vascular imaging; aortic diseases; aortic aneurysm; arteriovenous malformation; pelvic venous disorder; endovenous procedures; pal-liative therapy concept
(This special issue belongs to the Section Vascular Medicine)
Musculoskeletal Imaging and Intervention: 2nd Edition submission deadline 25 May 2026 | Viewed by 80 | Submission Open
Keywords: ultrasound; invasive physiotherapy; minimally invasive surgical procedures; magnetic resonance; image analysis
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Clinical Advances in the Management of Abdominal and Thoracoabdominal Aortic Aneurysms
edited by
submission deadline 25 May 2026 | Viewed by 80 | Submission Open
Keywords: abdominal aneurysm; thoraco-abdominal; computed-tomography angiography; branched endograft; branched endovascular aortic repair; fenestrated endograft; open surgery; 3-D printing
(This special issue belongs to the Section Vascular Medicine)
Clinical Diagnosis and Treatment of Demyelinating Diseases
edited by and John S. Tzartos
submission deadline 25 May 2026 | Viewed by 79 | Submission Open
Keywords: demyelinating diseases of the CNS; demyelinating diseases of the PNS; multiple sclerosis; neuromyelitis optica spectrum disorder (NMOSD); myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD); clinical diagnosis; biomarkers; therapeutics
(This special issue belongs to the Section Clinical Neurology)
How Clinicians See the Use of AI in Psychiatry
edited by
submission deadline 25 May 2026 | Viewed by 79 | Submission Open
Keywords: artificial intelligence; psychiatry; patient care; psychotherapy
(This special issue belongs to the Section Mental Health)
Acute and Chronic Heart Failure: Clinical Updates and Perspectives—2nd Edition
edited by Luigi Cappannoli and Cristina Aurigemma
submission deadline 25 May 2026 | Viewed by 70 | Submission Open
Keywords: acute heart failure; chronic heart failure; devices; drug therapy; percutaneous ventricular assist devices; cardiogenic shock; arrhythmias; ischemic heart disease
(This special issue belongs to the Section Cardiovascular Medicine)
Epilepsy and Cerebrovascular Disorders
edited by
submission deadline 25 May 2026 | Viewed by 63 | Submission Open
Keywords: epilepsy; cerebrovascular disorders; stroke; post-stroke epilepsy; neuroinflammation; neuroimaging; electroenceph-alography; biomarkers; antiepileptic treatment; translational neuroscience
(This special issue belongs to the Section Clinical Neurology)
Advances in Kidney Transplantation: 2nd Edition
edited by Pedro Ruiz-Esteban, Domingo Hernández and Veronica López
submission deadline 25 May 2026 | Viewed by 53 | Submission Open
Keywords: kidney transplant; acute rejection; biomarkers; artificial intelligence; post-transplant complications; graft survival
(This special issue belongs to the Section Nephrology & Urology)
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