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Approaches and Challenges in Oral Rehabilitation

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Dentistry, Oral Surgery and Oral Medicine".

Deadline for manuscript submissions: 25 November 2025 | Viewed by 411

Special Issue Editors


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Guest Editor
Department of Dentistry and Oral Surgery, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya 663-8501, Japan
Interests: neuroplasticity; dentistry; rehabilitation; interventional study; nutrition; prosthetic treatment; mastication
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Guest Editor
Department of Removable Prosthodontics, Graduate School of Dentistry, The University of Osaka, 1-8 Yamadaoka, Suita 565-0871, Japan
Interests: dentistry; prosthetic treatment; mastication; general health; epidemiology; oral function

Special Issue Information

Dear Colleagues,

Oral rehabilitation focuses not only on maintaining and restoring oral functions, such as eating and swallowing, but also on improving oral hygiene and advancing dental treatment. It plays a critical role in improving the function, appearance, and overall health of individuals with oral and systemic diseases. Advances in dental technology, neuroscience, and interdisciplinary care have expanded oral rehabilitation’s capabilities, broadened its scope, and introduced new treatment options. However, several challenges remain. Key questions include whether oral rehabilitation can optimize long-term disease management, its potential and limitations in addressing neuromuscular function, and how best to integrate oral hygiene improvements and dental treatments into a broader healthcare framework. While research is continuing to unravel the complex relationships between oral function, neuroplasticity, and systemic health, many aspects remain unclear. In this Special Issue, we will showcase valuable evidence, the latest findings, innovative approaches, emerging challenges, and future directions in oral rehabilitation. By launching this Special Issue, we hope to provide new insights that will ultimately lead to improved patient care.

Dr. Yoko Hasegawa
Dr. Takayuki Kosaka
Guest Editors

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Keywords

  • oral rehabilitation
  • oral health
  • systemic health
  • dental innovation
  • neuroplasticity

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Published Papers (1 paper)

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Research

11 pages, 217 KiB  
Article
Effectiveness of a Salivary Testing System to Screen for Periodontal Disease: A Cross-Sectional Study from the NOSE Study
by Takayuki Kosaka, Shuri Fushida, Masahiro Wada, Tomoya Gonda, Kodai Hatta, Masae Kuboniwa, Arisa Wada, Sumiyo Hashimoto, Hiromi Hatanaka, Makiko Higashi, Takeshi Kikuchi, Keiji Terauchi, Michiko Kido, Yuya Akagi, Kei Kamide, Mai Kabayama and Kazunori Ikebe
J. Clin. Med. 2025, 14(14), 4965; https://doi.org/10.3390/jcm14144965 - 14 Jul 2025
Viewed by 278
Abstract
Background: This study aimed to evaluate the effectiveness of a saliva-based screening method for periodontal disease among community-dwelling older adults in Japan. Methods: A total of 372 study participants (mean age: 73.1 years) with 20 or more remaining teeth were included in [...] Read more.
Background: This study aimed to evaluate the effectiveness of a saliva-based screening method for periodontal disease among community-dwelling older adults in Japan. Methods: A total of 372 study participants (mean age: 73.1 years) with 20 or more remaining teeth were included in the study. Of the six parameters assessed by the Salivary Multi Test (SMT), this study focused on the three parameters related to periodontal disease: occult blood, leukocytes, and proteins. Periodontal tissue examinations were performed based on the Community Periodontal Index (CPI) using partial mouth recording. To evaluate screening accuracy, the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were calculated for each of the three markers: occult blood, leukocytes, and proteins. Receiver operating characteristic (ROC) analysis was performed for each SMT item, and area under the curve (AUC) was calculated. Logistic regression analysis was used to calculate the odds ratios for combinations of SMT markers, with the presence of periodontal pockets and gingival inflammation as the respective outcome variables. Results: Among the individual markers, occult blood showed the highest diagnostic performance for detecting both periodontal pockets and gingival inflammation. The combination of elevated occult blood and leukocyte levels yielded the highest odds ratios for both periodontal pockets and gingival inflammation. Conclusions: While several SMT markers showed associations with periodontal conditions, their utility for screening in older Japanese adults remains to be further validated. Combining markers may help improve diagnostic performance, but additional studies are warranted. Full article
(This article belongs to the Special Issue Approaches and Challenges in Oral Rehabilitation)
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