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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Advances in Gut Microbiota and Its Interaction with Immune System
edited by
submission deadline 30 Aug 2024 | Viewed by 206 | Submission Open
Keywords: gut microbiota; dysbiosis; gut permeability; intestinal inflammation; autoimmunity; IBD
(This special issue belongs to the Section Molecular Immunology)
Molecular Targets and Immunotherapy for Autoimmune Diseases
edited by
submission deadline 30 Aug 2024 | Viewed by 202 | Submission Open
Keywords: autoimmunity; autoimmune diseases; immunotherapy; signaling pathway; molecular targets; antibody; T cells; B cells
(This special issue belongs to the Section Molecular Immunology)
Glycobiology of Health and Diseases
edited by
submission deadline 30 Aug 2024 | Viewed by 201 | Submission Open
Keywords: sugar chains; carbohydrate-recognizing molecules; glycolipids
(This special issue belongs to the Section Molecular Biology)
Recent Advances in Allergen Analysis
edited by
submission deadline 30 Aug 2024 | Viewed by 200 | Submission Open
(This special issue belongs to the Section Molecular Biology)
Cellular and Molecular Mechanisms of Severe Combined Immunodeficiencies (SCID): From Newborn Screening to Treatment Innovations
edited by Mirjam D. Van Der Burg and Arjan C. Lankester
submission deadline 30 Aug 2024 | Viewed by 198 | Submission Open
Keywords: SCID; newborn screening; HSCT; gene therapy; gene editing; monogenic defects; mechanisms of disease; T-cell development; thymus; in vitro artificial thymic organoid systems
(This special issue belongs to the Section Molecular Immunology)
Unraveling Apoptosis: Deciphering Molecular Mechanisms
edited by
submission deadline 30 Aug 2024 | Viewed by 174 | Submission Open
Keywords: apoptosis; development; microenvironment; mitochondria dysfunction; molecular mechanisms; tumors; degenerative diseases; diabetes; metabolic diseases; neurodegenerative disease; novel pharmacological strategies
(This special issue belongs to the Section Biochemistry)
Pathophysiological Research into and Treatment of Pregnancy Complications
edited by
submission deadline 30 Aug 2024 | Viewed by 164 | Submission Open
Keywords: complications of pregnancy; preterm labor; placental abruption; pre-eclampsia; gestational diabetes
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Inflammatory Airway Diseases: Diagnosis, Pathology, Molecular Mechanisms and Treatment Options
edited by
submission deadline 30 Aug 2024 | Viewed by 161 | Submission Open
Keywords: inflammatory airway diseases; asthma; COPD; anti-inflammatory
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
New Insights into Viral Vector Mediated Gene Therapy
edited by
submission deadline 30 Aug 2024 | Viewed by 161 | Submission Open
Keywords: viral vector; gene therapy; gene delivery; adenovirus; adeno-associated virus; lentivirus; analytics; preclinical testing; inherited disorders
(This special issue belongs to the Section Molecular Microbiology)
Infection and Immunity after Transplantation
edited by Bin Cho and Hyun Mi Kang
submission deadline 30 Aug 2024 | Viewed by 157 | Submission Open
Keywords: solid organ transplantation; hematopoietic stem cell transplantation; opportunistic infections; bacteria; fungus; virus; immune reconstitution; humoral immunity; adaptive immunity
(This special issue belongs to the Section Molecular Immunology)
The Intersection of Drug Abuse, Neurotoxicity and Neurodegenerative Diseases submission deadline 30 Aug 2024 | Viewed by 154 | Submission Open
Keywords: drugs of abuse; neurotoxicity; neurodegeneration; brain health; substance use disorders; therapeutic interventions
(This special issue belongs to the Section Molecular Neurobiology)
Stem Cells in Musculoskeletal Tissue Engineering, Repair, and Regeneration submission deadline 30 Aug 2024 | Viewed by 151 | Submission Open
Keywords: stem cells; musculoskeletal; tissue engineering; repair; regeneration; regenerative medicine
(This special issue belongs to the Section Molecular Biology)
Advances in Bioactive Molecules submission deadline 30 Aug 2024 | Viewed by 145 | Submission Open
Keywords: antimicrobial profile; drug discovery; tissue regeneration; analytical techniques; chemical synthesis; high-throughput screening; therapeutic development; surface functionalization; biomaterial integration; bio-based
(This special issue belongs to the Section Molecular Biology)
Pharmacological Treatment of Neuroinflammation
edited by Beatrice Polini
submission deadline 30 Aug 2024 | Viewed by 135 | Submission Open
Keywords: microglia; neuroinflammation; neurodegeneration; Alzheimer’ s disease; Parkinson’ s disease; therapeutic; natural molecules
(This special issue belongs to the Section Molecular Neurobiology)
Advances in Riboswitch Inhibitors submission deadline 30 Aug 2024 | Viewed by 131 | Submission Open
Keywords: riboswitch; noncoding RNA; antibiotics; resistance; bacteria; antimicrobial resistance
(This special issue belongs to the Section Molecular Biology)
Advances in Molecular Mechanisms of Neurodegenerative Diseases
edited by Aslihan Ugun-Klusek
submission deadline 30 Aug 2024 | Viewed by 130 | Submission Open
Keywords: neurodegeneration; Parkinson’ s disease; Alzheimer’ s disease; molecular signalling; neuronal death
(This special issue belongs to the Section Molecular Neurobiology)
Neuroprotective Effects of Food Ingredients submission deadline 30 Aug 2024 | Viewed by 129 | Submission Open
Keywords: neuroprotection; Parkinson; Alzheimer; bioactive compounds; agri-food by-products; chemical characterization; foodomics; metabolomics; molecular mechanisms
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Application of Mass Spectrometry and Chromatography in Biomedicine
edited by
submission deadline 30 Aug 2024 | Viewed by 125 | Submission Open
Keywords: mass spectrometry; chromatography; LC-MS; GC-MS; biomarker discovery; pharmaceuticals; metabolimics; proteomics; lipidomics
(This special issue belongs to the Section Molecular Biophysics)
Molecular Insights into Liver Diseases
edited by Sergio Rodríguez-Tajes
submission deadline 30 Aug 2024 | Viewed by 122 | Submission Open
Keywords: molecular aspect; liver disease; hepatic stellate cells; immune cells; cirrhosis; hepatitis; hepatocytes; therapeutic target; next-generation sequencing; epigenetics
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Natural Product-Based Strategy for Skin Inflammatory Disorders and Regeneration
edited by
submission deadline 30 Aug 2024 | Viewed by 121 | Submission Open
Keywords: inflammatory skin disorders; skin wound healing and regeneration; skin aging; bioactive natural compound; derivative and conjugate; plant extract; beneficial effect and application; molecular mechanism
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Diseases of the Lymphatic System: Pathophysiology and Molecular Imaging
edited by
submission deadline 30 Aug 2024 | Viewed by 119 | Submission Open
(This special issue belongs to the Section Molecular Immunology)
The Role of Hormones and Nutrients in Health and Disease
edited by
submission deadline 30 Aug 2024 | Viewed by 113 | Submission Open
Keywords: sensory nutrients; steroid hormones; oxidative stress; inflammation; Nrf2 pathway; neurodegenerative disorders; psychiatric diseases; personalized nutritional therapy; organoid technology
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Molecular Research of Gut Microbiota in Human Health and Diseases submission deadline 30 Aug 2024 | Viewed by 108 | Submission Open
Keywords: gut microbiota; gut metabolites; gastroenterology; microbiology; inflammation; human diseases
(This special issue belongs to the Section Molecular Microbiology)
Molecular Mechanisms and Regulation in Chronic Kidney Diseases
edited by
submission deadline 30 Aug 2024 | Viewed by 108 | Submission Open
Keywords: chronic kidney disease; pathophysiology; genetic and epigenetic factors; metabolic and inflammatory pathways
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Gastrointestinal Disease: Exploring the Interplay between Inflammation, Autoimmunity, and Cancer
edited by Spyridon Siakavellas
submission deadline 30 Aug 2024 | Viewed by 106 | Submission Open
Keywords: gastrointestinal disease; inflammation; autoimmunity; gut microbiota
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Latest Review Papers in Molecular Nanoscience 2024
edited by Andre Lee and
submission deadline 30 Aug 2024 | Viewed by 103 | Submission Open
Keywords: nanomaterials; nanomedicine; nanoparticles; nanoassemblies; nanotechnology; nanocatalysts; nanocomposites
(This special issue belongs to the Section Molecular Nanoscience)
Modified Composite Materials: Design, Properties and Applications in Biological Fields
edited by
submission deadline 30 Aug 2024 | Viewed by 99 | Submission Open
Keywords: modified composite materials; biomedical engineering; drug delivery systems; treatment of diseases; tissue engineering
(This special issue belongs to the Section Materials Science)
The Roles of Deubiquitylating Enzymes (DUBs) in Cancer Inflammation submission deadline 30 Aug 2024 | Viewed by 99 | Submission Open
Keywords: deubiquitylating enzymes; ubiquitin; cancer; immuno-oncology; immunity
(This special issue belongs to the Section Biochemistry)
Heart Failure: From Molecular Basis to Therapeutic Strategies
edited by
submission deadline 30 Aug 2024 | Viewed by 99 | Submission Open
Keywords: heart failure; cardiac metabolism; mitochondria; inflammatory pathway; neurohormonal system; therapeutical strategies
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Periodontal Disease, Association with Systemic Conditions and Periodontal Pathogens 2.0
edited by Evangelos Papathanasiou
submission deadline 30 Aug 2024 | Viewed by 97 | Submission Open
Keywords: periodontal disease; periodontitis; periodontal medicine; periodontal– systemic interactions; immune response; periodontal pathogens
(This special issue belongs to the Section Molecular Immunology)
Electron and Radical Induced Chemistry and Related Applications
edited by
submission deadline 30 Aug 2024 | Viewed by 94 | Submission Open
Keywords: ion beam interaction with biomoles; low energy electrons and positron interactions; reactive species; modelling particle transport; molecular radiosensitizers; molecular-damaging reactions; ion beam radiotherapy; intraoperational electron beam therapy; radiobiological studies
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Natural Products in Lifestyle-Related Diseases: Molecular Mechanisms, Prevention and Treatments
edited by
submission deadline 30 Aug 2024 | Viewed by 93 | Submission Open
Keywords: natural products; crude drugs; lifestyle-related diseases; diabetes mellitus; cardiovascular disease; non-alcoholic hepatosteatosis; cancer; sarcopenia; Alzheimer’ s disease
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Mesenchymal Stem Cells in Health and Disease 3.0 submission deadline 30 Aug 2024 | Viewed by 91 | Submission Open
Keywords: mesenchymal stem cells; extracellular vesicles; stem cells; exosome; MSC-EVs
(This special issue belongs to the Section Molecular Biology)
Modern Plant Cell Biotechnology: From Genes to Structure 2.0 submission deadline 30 Aug 2024 | Viewed by 89 | Submission Open
Keywords: genetic engineering techniques; gene modification; gene editing; regulation of gene expression; plant cell biotechnology
(This special issue belongs to the Section Molecular Plant Sciences)
Heavy Metal Toxicity and Female Infertility, Pregnancy Disorders, Fetal Growth and Development
edited by
submission deadline 30 Aug 2024 | Viewed by 85 | Submission Open
Keywords: pregnancy disorders; preeclampsia; pre-term labor; endometriosis; infertility; uterine artery remodeling; ovarian failure; polycystic ovarian syndrome (PCOS) and premature ovarian failure (POF)]; fetal growth restriction; placental pathogenesis
(This special issue belongs to the Section Molecular Toxicology)
Cell Pathways Underlying Neuronal Differentiation
edited by
submission deadline 30 Aug 2024 | Viewed by 84 | Submission Open
Keywords: neural progenitor cells; neuronal cell lines; induced pluripotent stem cells; neuronal phenotype; brain tumor cells
(This special issue belongs to the Section Molecular Neurobiology)
Emerging Molecular Research Approaches for Fungal Infections
edited by
submission deadline 30 Aug 2024 | Viewed by 84 | Submission Open
Keywords: fungi; fungal infection; molecular approach
(This special issue belongs to the Section Molecular Microbiology)
TRP Channel, 2nd Edition
edited by
submission deadline 30 Aug 2024 | Viewed by 84 | Submission Open
Keywords: TRP; TRPAnkyrin; TRPCanonical; TRPMelastatin; TRPPolycystin; TRPVanilloid
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Pathways and Therapeutic Strategies for Fibrotic Conditions
edited by
submission deadline 30 Aug 2024 | Viewed by 83 | Submission Open
Keywords: fibrosis; fibrotic disorders; autoimmune diseases; cancer; adipose tissue fibrosis; repurposed drugs; gene therapies; cytokine-mediated pathways; anti-fibrotic therapies; systemic diseases
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Computational Methods for Studying the Effects of Radiation on Human Beings submission deadline 30 Aug 2024 | Viewed by 82 | Submission Open
Keywords: DNA damage; biophysical models; DNA geometrical models; computational radiobiology; Monte Carlo simulations; ionizing radiation; heavy ions; DNA damage repair
(This special issue belongs to the Section Molecular Biophysics)
Advances in Bone Regeneration Biology
edited by
submission deadline 30 Aug 2024 | Viewed by 81 | Submission Open
Keywords: bone; stem cells; immunomodulation; biomaterial; regeneration; materials; biomimetic
(This special issue belongs to the Section Molecular Biology)
Research of Hydroxyapatite-Based Materials and Their Applications
edited by
submission deadline 30 Aug 2024 | Viewed by 80 | Submission Open
Keywords: hydroxyapatite; nanobiocomposite; biomedical applications; coatings; environment remediation; biological properties; drug delivery; pollutant adsorption efficiency; morphology and structural features
(This special issue belongs to the Section Materials Science)
Molecular Advances in Neuroprotective Strategies for Ocular Diseases
edited by
submission deadline 30 Aug 2024 | Viewed by 77 | Submission Open
Keywords: neuroprotection; neurodegeneration; neuronal cell death; regeneration; pyroptosis; inflammation; optic nerve injuries; translational research; photoreceptors; retinal ganglion cells; inflammasomes; microglia; complement pathways
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Ferroptosis: Emerging Mechanisms, Physiological Functions, and Therapeutic Applications
edited by
submission deadline 30 Aug 2024 | Viewed by 77 | Submission Open
Keywords: ferroptosis; biomarker; iron metabolism; diseases; precision medicine
(This special issue belongs to the Section Biochemistry)
Anxiolytic or Antidepressant Activity Components in Medicinal Plants
edited by Carolina López-Rubalcava
submission deadline 30 Aug 2024 | Viewed by 76 | Submission Open
Keywords: phytopharmacology; anxiety; depression; medicinal plants; animal models
(This special issue belongs to the Section Bioactives and Nutraceuticals)
New Insights into the Pathogenesis of Type 1 Diabetes submission deadline 30 Aug 2024 | Viewed by 75 | Submission Open
Keywords: type 1 diabetes; insulin-dependent diabetes mellitus; human leukocyte antigen (HLA); pathogenesis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Plant Resistance and Tolerance to Salt–Alkaline Stress: Current Status and Future Directions
edited by
submission deadline 30 Aug 2024 | Viewed by 73 | Submission Open
Keywords: salt– alkaline stress; abiotic stress; molecular genetics; multi-omics analysis; plant breeding; climate change; agricultural sustainability
(This special issue belongs to the Section Molecular Plant Sciences)
Viral Infections and Immune Responses submission deadline 30 Aug 2024 | Viewed by 73 | Submission Open
Keywords: virus; infections; immune response; T-cells; B-cells; antibodies; neutralizing activity
(This special issue belongs to the Section Molecular Immunology)
Photodynamic Therapy for Cancer Treatment
edited by
submission deadline 30 Aug 2024 | Viewed by 72 | Submission Open
Keywords: cancer; photodynamic theapy; photosensitizer; cell death; technological advances
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Biological Application of Natural Products Antioxidant Activity
edited by Adriana C. E. Graziano and Rosanna Avola
submission deadline 30 Aug 2024 | Viewed by 69 | Submission Open
Keywords: natural products; natural product chemistry; plant extract; polyphenols; antioxidant activity; nutraceuticals; mechanism of action; phytochemicals
(This special issue belongs to the Section Bioactives and Nutraceuticals)
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