International Journal of Molecular Sciences

Cellular Plasticity and Tissue Remodeling in Chronic Diseases and Cancer

edited by

submission deadline 30 Sep 2026 | Viewed by 687 | Submission Open

Keywords: epithelial plasticity; epithelial– mesenchymal transition (EMT); tissue remodeling; chronic diseases; cancer; fibrosis; inflammatory signaling; extracellular matrix (ECM); organoids; air– interface liquid culture advanced in vitro models

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Inflammatory and Metabolic Biomarkers in Disease Prediction and Prognosis

edited by

Recep Dokuyucu

submission deadline 30 Sep 2026 | 2 articles | Viewed by 660 | Submission Open

Keywords: inflammation; biomarkers; metabolic indices; triglyceride-glucose index; inflammatory ratios; risk stratification; prognosis; cardiovascular diseases; critical care; neuroinflammation; endocrine disorders; composite inflammatory scores; artificial intelligence; personalized medicine; clinical biochemistry

(This special issue belongs to the Section Biochemistry)

Nanotechnology-Driven Insights into Plants: Mechanisms, Detection, and Sustainable Control

edited by

Ezzeldin Ibrahim

submission deadline 30 Sep 2026 | Viewed by 647 | Submission Open

Keywords: nanotechnology; plant– pathogen interactions; plant immunity; nanoparticles; nano-enabled diagnostics; disease management; antimicrobial nanomaterials; nano-biocontrol; sustainable agriculture; phytopathology

(This special issue belongs to the Section Molecular Nanoscience)

The Role of Cytokines in Immunological Disorders and Their Therapies

edited by

Mohammad Massumi

submission deadline 30 Sep 2026 | Viewed by 608 | Submission Open

Keywords: cytokines; autoimmune diseases; autoinflammatory diseases; TNF-alpha; interleukin-17; IL-6; immune tolerance; biologic therapy; JAK inhibitors; inflammation

(This special issue belongs to the Section Molecular Immunology)

Molecular and Immunological Mechanisms Associated with Exercise

edited by

Sebastian Del Rosso

submission deadline 30 Sep 2026 | Viewed by 522 | Submission Open

Keywords: signaling pathways; exercise training adaptation; exercise and mitochondrial health; skeletal muscle secretome; exercise and extracellular vesicles; myokines; exerkines; molecular immune responses to exercise

(This special issue belongs to the Section Molecular Biology)

Cell Therapies: Cellular Mechanisms and Genetic Engineering

edited by Shirley O'Dea

submission deadline 30 Sep 2026 | Viewed by 496 | Submission Open

Keywords: cell engineering; advanced therapy medicinal products (ATMPs); cell fate control; translational cell therapy; next-generation cell therapy platforms; scalable cell manufacturing; personalized cell-based medicine; clinical translation; cell therapy delivery systems; bioprocessing of engineered cells

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Methodological Advances in Phytochemical Analysis

edited by

Mehmet Yaman

and

Kadir Uğurtan YILMAZ

submission deadline 30 Sep 2026 | 2 articles | Viewed by 489 | Submission Open

Keywords: advanced phytochemical profiling; high-resolution mass spectrometry; green extraction methodologies; chemometric data processing; bioactive metabolite elucidation

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Neuroimmune Circuitry: Advances in Neuronal Regulation of Immunity

edited by

Roberto De Luca

submission deadline 30 Sep 2026 | Viewed by 472 | Submission Open

Keywords: neuroimmunology; neuronal circuits; molecular signaling; hypothalamus; autonomic regulation; neuropeptides; GPCR signaling; inflammation; cytokines; transcriptional regulation

(This special issue belongs to the Section Molecular Immunology)

Glial Cells in Brain and Eye: Emerging Mechanisms and Functions in Health and Disease

edited by

Mario E. Guido

submission deadline 30 Sep 2026 | Viewed by 459 | Submission Open

Keywords: glial cells; brain & eye (retina); health & disease; neuronal regulation; therapeutic strategies; CNS; glia biology; cellular interactions

(This special issue belongs to the Section Molecular Biology)

Plant Metabolism and Genetics

edited by

Dalu Li

submission deadline 30 Sep 2026 | 1 articles | Viewed by 449 | Submission Open

Keywords: plant metabolism; genetics; genomics; multi-omics integration; secondary/specialized metabolites; biosynthetic pathways; metabolic engineering crop improvement

(This special issue belongs to the Section Molecular Plant Sciences)

Nutritional Approaches to Cardiovascular Health

edited by Aleksandar Kibel

submission deadline 30 Sep 2026 | Viewed by 446 | Submission Open

Keywords: cardiovascular disease; dietary patterns; hypertension; dyslipidemia; inflammation; endothelial function; omega-3 fatty acids; dietary fiber; gut microbiome; precision nutrition

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Diverse Biomolecular Probes in the Development of Single-Molecule Biosensors

edited by

Kevin D. Belfield

and

Xiaohan Chen

submission deadline 30 Sep 2026 | Viewed by 445 | Submission Open

Keywords: biomolecular probes; single-molecule method; biosensors; diseases diagnosis; biomarkers; nanotechnology

(This special issue belongs to the Section Materials Science)

Carbon-Based Nanomaterials: From Synthesis and Functionalization to Biomedical Applications

edited by

Marta Kutwin

submission deadline 30 Sep 2026 | 1 articles | Viewed by 442 | Submission Open

Keywords: carbon-based nanomaterials; graphene; graphene oxide; carbon nanotubes; fullerenes; carbon quantum dots; surface functionalization; nano– bio interface; drug and gene delivery; cancer nanotherapeutics

(This special issue belongs to the Section Materials Science)

In Honor of the 76th Birthday of Dr. Rachel Mata Essayag, a Distinguished Pioneer in Natural Products Research in Mexico

edited by

Fernando Calzada

submission deadline 30 Sep 2026 | Viewed by 440 | Submission Open

Keywords: pharmacognosy; natural products; phytochemistry; diabetes; cancer; diarrhea; viral infections; bacterial infections; drug development; in vivo; ex vivo; in vitro; in silico

(This special issue belongs to the Section Molecular Pharmacology)

Extracellular Vesicles in Cancer and Tumor Microenvironment

edited by Celeste Caruso Bavisotto,

Alessandra Maria Vitale

and

Giuseppa D’Amico

submission deadline 30 Sep 2026 | 2 articles | Viewed by 437 | Submission Open

Keywords: EVs; cancer; tumor cell-derived EVs (TCdEVs); tumor microenvironment (TME); tumor-associated antigens (TAAs)

(This special issue belongs to the Section Molecular Oncology)

Advances in Omics Approaches in Chronic Metabolic Diseases

edited by Ramos-López Omar

submission deadline 30 Sep 2026 | 1 articles | Viewed by 427 | Submission Open

Keywords: chronic metabolic diseases; obesity; diabetes; cardiovascular disease; fatty liver; genomics; epigenomics; metagenomics; metabolomics; proteomics

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Oral Squamous Cell Carcinoma: From Pathogenesis to Targeted Therapy

edited by

Giuseppina Campisi

and

Vito Carlo Alberto Caponio

submission deadline 30 Sep 2026 | Viewed by 424 | Submission Open

Keywords: oral cancer; oral potentially malignant disorders; omics; oral squamous cell carcinoma; leukoplakia; biomarkers; tumor microenvironment; immunotherapy; target therapy; HPV; multidisciplinary team

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular, Genetic, and Omics Approaches to Disorders in Bone–Inflammation Crosstalk

edited by

Paula Sandrin-Garcia

submission deadline 30 Sep 2026 | Viewed by 409 | Submission Open

Keywords: bone physiology; inflammatory; epigenetic regulation; molecular signaling pathways; cellular interactions

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

T Cell Receptor (TCR) Signaling at the Crossroads of Immunity, Tolerance, and Disease

edited by Amar Singh

submission deadline 30 Sep 2026 | Viewed by 396 | Submission Open

Keywords: T cell receptor (TCR) signaling; immune tolerance; effector T cell differentiation; regulatory T cells (Tregs; Tr1); T cell heterogeneity; metabolic reprogramming; T cell memory and exhaustion; TCR repertoire analysis; autoimmunity and inflammation; TCR-based immunotherapy; CAR-T cells

(This special issue belongs to the Section Molecular Immunology)

Novel Molecular Pathways and Therapeutic Strategies in Atherosclerotic Cardiovascular Disease

edited by

Elisabeta Badila

and Catalin Adrian Buzea

submission deadline 30 Sep 2026 | Viewed by 372 | Submission Open

Keywords: atherogenesis; vascular inflammation; immune modulation; lipid metabolism; clonal hematopoiesis (CHIP); endothelial dysfunction; plaque instability; epigenetic regulation; molecular signaling pathways; precision cardiovascular medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cellular Pathways and Cytokine Networks in Tuberous Sclerosis: Mechanisms and Therapeutic Targets

edited by Uchenna John Unachukwu

submission deadline 30 Sep 2026 | Viewed by 372 | Submission Open

Keywords: mTOR signaling dysregulation; neurocristopathy; cytokine crosstalk; TSC1/TSC2 complex; epigenetic modifiers; metabolic reprogramming; molecular biomarkers; spatial transcriptomics

(This special issue belongs to the Section Molecular Biology)

Valorization of Agri-Food Wastes: Extraction, Characterization and Functional Applications of Bioactive Compounds

edited by Pittaya Chaikham

submission deadline 30 Sep 2026 | Viewed by 370 | Submission Open

Keywords: agri-food waste valorization; bioactive compounds; functional foods; green extraction; food sustainability; plant-based ingredients; antioxidants; circular economy; probiotics; food processing

(This special issue belongs to the Section Biochemistry)

Molecular Advances of Gut–Brain Communications

edited by

Walter Pirovano

submission deadline 30 Sep 2026 | Viewed by 367 | Submission Open

Keywords: gut-brain axis; microbiome; molecular profiling; omics/multi-omics data; functional measurements; analytical methods; computational methods; neurological disorders; neuropsychiatric disorders

(This special issue belongs to the Section Molecular Biology)

Advances in Neuroscience of Mental Disorders: Neuropsychological, Neurobiological and Neuromolecular Perspectives

edited by

Phakkharawat Sittiprapaporn

submission deadline 30 Sep 2026 | Viewed by 365 | Submission Open

Keywords: mental health; mental disorders; neurosciences; neurobiological markers

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Diagnostics and Therapeutic Advances in Hematology: From Mechanisms to Clinical Applications

edited by

Akiyoshi Takami

and

Jorge Luis Espinoza

submission deadline 30 Sep 2026 | Viewed by 361 | Submission Open

Keywords: hematology; molecular diagnostics; immunology; biomarkers; hematopoietic cell transplantation; bone marrow failure; hematologic malignancies; plasma cell disorders; translational research; therapeutic strategies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

CAR-T Cell Biology and Clinical Translation

edited by

Antonio Pérez Martínez

and

Daniel Ka Leung Cheuk

submission deadline 30 Sep 2026 | Viewed by 361 | Submission Open

Keywords: chimeric antigen receptor (CAR) T cells; gene engineering; genome editing; T‑cell exhaustion; tumor microenvironment; cytokine release syndrome (CRS); ICANS (immune effector cell– associated neurotoxicity syndrome); allogeneic CAR‑T cells; dual‑targeting CAR‑T cells; point‑of‑care manufacturing

(This special issue belongs to the Section Molecular Immunology)

A Window to the Brain: From Retinal Cellular and Soluble Biomarkers Towards Neurodegeneration

edited by

Bijorn Omar Balzamino

,

Rosanna Squitti

and

Alessandra Micera

submission deadline 30 Sep 2026 | Viewed by 357 | Submission Open

Keywords: retinal signaling; oxidative stress; retinal neurodegeneration; biomarkers; therapeutic targets

(This special issue belongs to the Section Molecular Neurobiology)

Omega-6 and Omega-3 Fatty Acid Imbalance: Roles in Human Health and Pathogenesis of Diseases

edited by

Jing X. Kang

submission deadline 30 Sep 2026 | Viewed by 356 | Submission Open

Keywords: omega-6/omega-3 ratio; omega-6 fatty acids; omega-3 fatty acids; omega-6/omega-3 imbalance; lipid metabolism; inflammation; chronic diseases; cardiovascular disease; cancer; metabolic syndrome; neurodegenerative diseases; autoimmune diseases; nutritional interventions; polyunsaturated fatty acids (PUFAs); molecular mechanisms; disease pathogenesis; disease management; health promotion

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Emerging Cardiovascular Drugs and Nutraceuticals: Mechanistic Insights, Translational Research and Clinical Impacts

edited by Pietro Mazzeo,

Vincenzo Vestuto

and Elena Mele

submission deadline 30 Sep 2026 | Viewed by 355 | Submission Open

Keywords: cardiovascular disease; drug mechanisms; nutraceuticals; precision medicine; multi-omics approaches

(This special issue belongs to the Section Molecular Pharmacology)

T Cell Immunity in Emerging Respiratory Viral Infections: Mechanisms, Dysregulation, and Therapeutic Targets

edited by Jian Zheng

submission deadline 30 Sep 2026 | 1 articles | Viewed by 350 | Submission Open

Keywords: T cell; coronavirus; immune memory; immunopathogenesis; aging

(This special issue belongs to the Section Molecular Immunology)

Mechanistic Studies on Microbiota–Host Interactions

edited by Min-Jin Kwak

submission deadline 30 Sep 2026 | 1 articles | Viewed by 347 | Submission Open

Keywords: microbiome; host-microbe interactions; gut-organ axis; extracellular vesicles; multi-omics; metagenomics; metabolomics; transcriptomics; barrier function

(This special issue belongs to the Section Molecular Microbiology)

Molecular Mechanisms of Nutrition in Muscle Development and Remodeling

edited by

Katya Naliwaiko

and

Matheus Felipe Zazula

submission deadline 30 Sep 2026 | Viewed by 342 | Submission Open

Keywords: muscle plasticity; nutrient signaling; protein turnover; metabolic flexibility; bioenergetics; redox homeostasis

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Pathogenic Escherichia coli: Cellular Biology, Mechanisms of Pathogenesis, Therapeutic Approaches and Strategies for Disease Intervention

edited by

Jorge Goldstein

submission deadline 30 Sep 2026 | Viewed by 338 | Submission Open

Keywords: enterohemorrhagic E. coli; EHEC; Shiga toxin-producing E. coli; STEC; HUS; inflammation; kidney; blood; brain; pathogenesis; antibodies; extraintestinal pathogenic E. coli; E. coli pathotypes

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Patient-Derived iPSC Models in Chronic Disease Research

edited by

Valentina Parra

submission deadline 30 Sep 2026 | Viewed by 337 | Submission Open

Keywords: induced pluripotent stem cells; patient-derived iPSCs; chronic diseases; disease modeling; molecular mechanisms; stem cell differentiation; gene editing; organoids; personalized medicine; multi-omics

(This special issue belongs to the Section Molecular Biology)

Research on Immune Mechanisms in Kidney Disease

edited by Niels Olsen Saraiva Câmara

submission deadline 30 Sep 2026 | Viewed by 325 | Submission Open

Keywords: kidney disease; molecular sensors; kidney metabolism; immunity; AKI to CKD transition

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Pharmacological Agents for Soft Tissue and Articular Injections: From Mechanisms to Clinical Applications

edited by

Carmelo Pirri

submission deadline 30 Sep 2026 | Viewed by 324 | Submission Open

Keywords: injectable pharmacological agents; musculoskeletal disorders; injection therapies; platelet-rich plasma (PRP); hyaluronic acid

(This special issue belongs to the Section Molecular Pharmacology)

Research Progress in Food Packaging Materials

edited by

Anouar Mouhoub

submission deadline 30 Sep 2026 | 1 articles | Viewed by 321 | Submission Open

Keywords: molecular design; intermolecular interactions; structure– property relationships; bio-based polymers; controlled release systems; active packaging; sustainable materials

(This special issue belongs to the Section Materials Science)

Pharmacological Research on Autoimmune Disease

edited by

Caio César de Souza Alves

and Sandra Bertelli Ribeiro de Castro

submission deadline 30 Sep 2026 | 1 articles | Viewed by 314 | Submission Open

Keywords: autoimmune diseases; plant-derived formulations; drug repurposing strategies; nanostructured delivery systems; complementary therapies; inflammatory; immune system; gut– brain axis

(This special issue belongs to the Section Molecular Pharmacology)

Cardioimmunology: Inflammation and Immunity in Cardiovascular Disease—2nd Edition

edited by David Rohde

submission deadline 30 Sep 2026 | 1 articles | Viewed by 314 | Submission Open

Keywords: myocardial infarction; heart failure; atherosclerosis; arterial hypertension; myocarditis; arrhythmia; inflammation; hematopoiesis; myelopoiesis; tissue macrophages; neutrophil biology; lymphocytes; endothelial cells; megakaryocytes; platelet biology; biomarkers

(This special issue belongs to the Section Molecular Immunology)

Genome-Wide Association Studies of Complex Diseases and Related Endophenotypes and Biomarkers

edited by M. Ilyas Kamboh

submission deadline 30 Sep 2026 | Viewed by 309 | Submission Open

Keywords: genome-wide association studies; complex diseases; endophenotypes; biomarkers; rare variants; copy number variants; diverse populations

(This special issue belongs to the Section Molecular Genetics and Genomics)

Pharmacological Mechanisms of Traditional Medicine in the Treatment of Pulmonary Diseases

edited by

Longshuang Huang

and

Chen Bai

submission deadline 30 Sep 2026 | Viewed by 298 | Submission Open

Keywords: traditional medicine; pulmonary diseases; herbal active components; pharmacological mechanisms; signaling pathways; clinical studies

(This special issue belongs to the Section Molecular Pharmacology)

Inflammatory Bowel Disease and Cardiometabolic Comorbidities: Molecular Mechanisms and Therapeutic Perspectives

edited by

Dimitrios Patoulias

and

Christos Mademlis

submission deadline 30 Sep 2026 | Viewed by 297 | Submission Open

Keywords: cardiovascular– kidney– metabolic syndrome; diabetes; obesity; cardiovascular disease; inflammatory bowel disease; Crohn’ s disease; ulcerative colitis; inflammation; endothelial dysfunction

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Nutritional Modulation of Lipid Metabolism and Gut–Tissue Axis: Mechanisms and Translational Insights

edited by

Piotr Dobrowolski

submission deadline 30 Sep 2026 | Viewed by 275 | Submission Open

Keywords: lipid metabolism; fatty acids; gut barrier; microbiota; metabolic programming; inflammation; FABP; nutrigenomics; obesity; zebrafish

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Computational Methods in Cancer Genomics and Molecular Oncology

edited by

Fabrício Alves Barbosa Da Silva

and Nicolas Carels

submission deadline 30 Sep 2026 | Viewed by 273 | Submission Open

Keywords: cancer genomics; computational biology; machine learning; precision oncology; multi-omics integration; molecular oncology; bioinformatics; tumor heterogeneity; biomarker discovery; single-cell sequencing

(This special issue belongs to the Section Molecular Genetics and Genomics)

New Advances in Infectious and Immunoinflammatory Mechanisms of Alzheimer's Disease

edited by Hiroshi Nakanishi

submission deadline 30 Sep 2026 | Viewed by 272 | Submission Open

Keywords: Alzheimer's Disease; amyloid; neuroinflammation

(This special issue belongs to the Section Molecular Neurobiology)

Genetic and Molecular Markers in Prostate Cancer

edited by Thaidy Moreno-Rodriguez

submission deadline 30 Sep 2026 | Viewed by 269 | Submission Open

Keywords: prostate cancer; genetic markers; androgen receptor signaling; molecular biomarkers; therapy resistance mechanisms; liquid biopsy; precision oncology

(This special issue belongs to the Section Molecular Oncology)

Role of Bifunctional Antibodies in Human Cancer

edited by

Alessandro Canella

submission deadline 30 Sep 2026 | Viewed by 268 | Submission Open

Keywords: bispecific antibodies; tumor immune microenvironment (TIME); cancer immunotherapy; tumor associated antigens; biomarker discovery; T cell engagers (BiTEs; TriTEs; TriKEs); dual affinity retargeting antibodies (DARTs); Fc engineering and Fcγ R modulation; tumor associated antigen (TAA) avidity optimization; immune reprogramming; bispecific antibody pharmacokinetics and biodistribution; antibody– drug conjugate (ADC) hybrid formats; bifunctional antibodies

(This special issue belongs to the Section Molecular Oncology)

Genetic Diversity, Founder Effects, and Migration in Neurodegeneration: Molecular and Population Perspectives

edited by

Dasiel Oscar Borroto-Escuela

submission deadline 30 Sep 2026 | Viewed by 268 | Submission Open

Keywords: neurodegeneration; population genetics; founder effects; genetic diversity; migration and disease risk; spinocerebellar ataxia; Alzheimer’ s disease; Parkinson’ s disease; genetic epidemiology; underrepresented populations

(This special issue belongs to the Section Molecular Neurobiology)

Integrating Multi-Omics Approaches in Fish Immunology to Improve Aquaculture Sustainability

edited by

Parasuraman Aiya Subramani

submission deadline 30 Sep 2026 | Viewed by 267 | Submission Open

Keywords: machine learning; network analysis; vaccine development; genomic selection; single-cell RNA-seq; meta-analysis; innate immunity; biomarker discovery

(This special issue belongs to the Section Molecular Immunology)

Molecular Advances in Pituitary Neuroendocrine Tumors: From Growth Control to Plasticity and Evolutionary Pathogenesis

edited by Ana Lucía De Paul and Liliana del Valle Sosa

submission deadline 30 Sep 2026 | Viewed by 266 | Submission Open

Keywords: tumor heterogeneity; tumor biomarkers; transcriptomics; molecular neuroscience; clinical treatment; pathogenesis; pituitary neuroendocrine tumors; neuroendocrine tumors; nonfunctional; PIT1; pituitary adenoma

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

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