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The Role of Melatonin in Plants: 3rd Edition

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Plant Sciences".

Deadline for manuscript submissions: 20 February 2026 | Viewed by 1009

Special Issue Editor


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Guest Editor
Department of Plant Ecophysiology, Faculty of Biology and Environmental Protection, University of Lodz, Banacha 12/16, 90-237 Lodz, Poland
Interests: melatonin role in plants; abiotic environmental stresses; plant physiology
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Special Issue Information

Dear Colleagues,

This Special Issue is the third volume of “The Role of Melatonin in Plants”. Since its discovery in 1958, for a long time, melatonin (N-acetyl-5-methoxytryptamine) functioned in the scientific consciousness (about 40 years) as only an animal hormone. In autotrophic microorganisms, melatonin was first described in 1991, and in 1995, it was detected in higher plants. Since then, this indoleamine has been investigated in numerous plant species and varieties in vivo, as well as in their organs, tissues, and cells cultivated in vitro. For 30 years, phytomelatonin has drawn great attention from plant physiologists for its wide distribution and multiple roles in various plant species. It is known that melatonin is an important modulator of plant development—it influences seed germination, the formation of roots and their architectures, seasonal and circadian rhythms, flowering time and fruit ripening, and leaf functioning (photosynthesis) and senescence. As amphiphilic, universal, very effective direct, and indirect antioxidants, melatonin affects the plant-cell redox status, and in this way, it interferes with a network of different signaling pathways. Moreover, melatonin is involved in plant immunity and increases plant tolerance to various abiotic stresses. Melatonin biosynthesis depends on environmental conditions and naturally increases under stress, so the application of exogenous melatonin as a plant biostimulant may be a good strategy for the improvement of yields in the face of climate change.

This Special Issue will focus on expanding knowledge related to the synthesis, distribution, and metabolism of plant melatonin (phytomelatonin), its multiple complex functions in plants and mechanisms of plant metabolism regulation, and the exogenous melatonin application methods for improving the development of crop plants, especially under different stress conditions.

Prof. Dr. Małgorzata M. Posmyk
Guest Editor

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Keywords

  • melatonin
  • phytomelatonin
  • plants
  • seed germination
  • seasonal and circadian rhythms
  • flowering
  • fruit ripening
  • plant immunity
  • abiotic stresses

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Published Papers (1 paper)

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Research

25 pages, 3277 KB  
Article
Melatonin: A Dual Protector of Pepper Plants Under Drought Stress via Antioxidant Defence and Glyoxalase-Mediated Cell Detoxification
by Şebnem Köklü Ardıç, Katarzyna Szafrańska and Ahmet Korkmaz
Int. J. Mol. Sci. 2025, 26(22), 11137; https://doi.org/10.3390/ijms262211137 - 18 Nov 2025
Viewed by 468
Abstract
Although the antioxidant role of melatonin in stress mitigation is well established, its multifunctionality may support plant tolerance to drought through additional mechanisms. This study aimed to evaluate melatonin’s contribution to both antioxidant defence and methylglyoxal (MG) detoxification—a harmful compound that disrupts cellular [...] Read more.
Although the antioxidant role of melatonin in stress mitigation is well established, its multifunctionality may support plant tolerance to drought through additional mechanisms. This study aimed to evaluate melatonin’s contribution to both antioxidant defence and methylglyoxal (MG) detoxification—a harmful compound that disrupts cellular balance under drought stress. The glyoxalase pathway, which is aided by glutathione, plays a pivotal role in MG detoxification. Therefore, we examined the impact of both endogenous and exogenous melatonin on this system. Two pepper genotypes differing in drought tolerance and endogenous melatonin levels were exposed to 12 days of drought following a 5 µM melatonin treatment. The drought-tolerant genotype, characterized by higher levels of endogenous melatonin, exhibited more efficient MG detoxification through increased glutathione and glyoxalase activities, reduced membrane damage and enhanced antioxidant capacity. Exogenous melatonin further mitigated the effects of drought by reducing MG accumulation and stimulating antioxidant and glyoxalase enzymes. Overall, both endogenous and applied melatonin enhances drought tolerance in pepper by activating antioxidant defences and the glyoxalase pathway. Full article
(This article belongs to the Special Issue The Role of Melatonin in Plants: 3rd Edition)
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