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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Epigenetic and Transcriptional Regulation in Aquaculture

edited by

Chan-Hee Kim

submission deadline 20 Sep 2026 | Viewed by 259 | Submission Open

Keywords: epigenetics; transcriptional regulation; trained immunity; DNA methylation; histone modifications; non-coding RNAs; disease prevention; aquaculture

(This special issue belongs to the Section Molecular Genetics and Genomics)

Identification and Analysis of Interspecies Interactions in Microbial Biofilms

edited by

Terence L. Marsh

submission deadline 20 Sep 2026 | Viewed by 257 | Submission Open

Keywords: biofilm; interspecies communication; biofilm demographics; competition; commensalism; parasitism; mutualism; methodologies

(This special issue belongs to the Section Molecular Microbiology)

Exopolysaccharides of Microbial Origin: Production, Analysis and Modification

edited by Marzena Jedrzejczak-Krzepkowska and

Karolina Ludwicka

submission deadline 20 Sep 2026 | Viewed by 255 | Submission Open

Keywords: exopolysaccharide; biopolymer; biofilm; microorganism; biosynthesis; genetic engineering; molecular design; modification; analysis

(This special issue belongs to the Section Molecular Microbiology)

Drug Discovery and Preclinical Pharmacology for Cognitive and Neuropsychiatric Disorders in Aging

edited by

Malgorzata Zaremba

submission deadline 20 Sep 2026 | Viewed by 254 | Submission Open

Keywords: aging brain; neural aging; neurodegeneration; neuropsychiatric disorders; late-life psychiatric disorders; dementia syndromes

(This special issue belongs to the Section Molecular Neurobiology)

Cytokines in Inflammatory Signaling: 3rd Edition

edited by

Waipo Chong

and

Daniela Novick

submission deadline 20 Sep 2026 | Viewed by 249 | Submission Open

Keywords: cytokines; inflammation; autoimmune diseases; immune homeostasis; signaling pathway; immunotherapy

(This special issue belongs to the Section Molecular Immunology)

Nanocompounds for Drug Delivery

edited by

Angela Staicu

Ana Maria Udrea

and

Andra Dinache

submission deadline 20 Sep 2026 | Viewed by 248 | Submission Open

Keywords: nanocompounds; drug delivery systems; targeted delivery; stimuli-responsive nanocarriers; hybrid nanostructures; controlled release; biocompatibility; photodynamic therapy (PDT); photothermal therapy (PTT)

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Mechanisms and Regulation of Glycoproteins in Cancer Biology

edited by

Josiah Ochieng

submission deadline 20 Sep 2026 | Viewed by 247 | Submission Open

Keywords: glycoprotein; metastasis; glycosylation; tumor progression

(This special issue belongs to the Section Molecular Biology)

Design and Application of Biocatalysts: Emerging Advances and Innovations in Enzyme Immobilization and Technologies

edited by

María Luján Ferreira

submission deadline 20 Sep 2026 | Viewed by 247 | Submission Open

Keywords: low-cost immobilization of enzymes; treatments post-immobilization; enzymatic synthesis of derivatives; polyesters depolymerization; hydroxy-acids polymerization; bioimprinting; post-immobilization treatments; composites

(This special issue belongs to the Section Biochemistry)

Advancements in Prognostic and Predictive Biomarkers for Advanced Prostate Cancer

edited by

Daniel Khalaf

submission deadline 20 Sep 2026 | Viewed by 246 | Submission Open

Keywords: biomarkers; predictive biomarkers; prognostic biomarkers; genomic biomarkers; biomarker directed therapy; advanced prostate cancer; metastatic prostate cancer; circulating tumour DNA; precision oncology; systemic therapy

(This special issue belongs to the Section Molecular Oncology)

Molecular Basis of Proteinopathies in Neurodegenerative Diseases

edited by

Kyoung Joo Cho

submission deadline 20 Sep 2026 | Viewed by 240 | Submission Open

Keywords: protein misfolding; neurodegenerative diseases; protein aggregation; proteostasis; post-translational modifications; ubiquitin– proteasome system; autophagy; targeted protein degradation; therapeutic strategies

(This special issue belongs to the Section Molecular Neurobiology)

Machine Learning in RNA and Chromatin Dynamics

edited by Haopeng Yu

submission deadline 20 Sep 2026 | Viewed by 240 | Submission Open

Keywords: machine learning; chromatin architecture; RNA dynamics; genomic foundation models; computational biology

(This special issue belongs to the Section Molecular Biology)

Research on Stem Cells in Neurological Disorders: Disease Modeling and Therapy

edited by

Xiaohua Jiang

submission deadline 20 Sep 2026 | Viewed by 239 | Submission Open

Keywords: disease modeling; molecular regulation; therapeutic intervention; neurological disorders

(This special issue belongs to the Section Molecular Neurobiology)

Updates on Human Embryonic Stem Cells

edited by

Yoon Young Kim

submission deadline 20 Sep 2026 | Viewed by 233 | Submission Open

Keywords: human embryonic stem cells; pluripotent stem cells; differentiation; pluripotency; cell-based therapy; embryo; disease modeling

(This special issue belongs to the Section Molecular Biology)

Advancements in the Electrochemical Detection of Biomolecules: From Sensing to Environmental Applications

edited by

Habibulla Imran

submission deadline 20 Sep 2026 | Viewed by 232 | Submission Open

Keywords: biomolecules; nanomaterials; biorecognition; biomolecular detection; electrochemical

(This special issue belongs to the Section Molecular Biophysics)

Latest Advances in Autoimmune and Inflammatory Rheumatic Diseases

edited by

Tanja Grubić-Kezele

submission deadline 20 Sep 2026 | Viewed by 222 | Submission Open

Keywords: autoimmune diseases; inflammatory diseases; rheumatic diseases; molecular mechanisms; pathogenesis; inflammation; central nervous system

(This special issue belongs to the Section Molecular Immunology)

Next-Generation Drug Development: Novel Modalities, AI Modeling, and Biomarkers

edited by

Chun-Yi Wu

submission deadline 20 Sep 2026 | Viewed by 222 | Submission Open

Keywords: pharmacokinetics; PK/PD modeling; biologics; antibody– drug conjugates (ADCs); biomarkers; artificial intelligence; novel therapeutic modalities; precision medicine

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Signatures for Risk Stratification and Therapeutic Decision-Making in Primary and Recurrent Prostate Cancer

edited by

Chengfei Liu

submission deadline 20 Sep 2026 | Viewed by 221 | Submission Open

Keywords: molecular mechanisms; biomolecular research; mechanistic insights; molecular pathways; translational biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Toxicology of Nano- and Microplastics: Mechanisms of Cellular Disruption and Biochemical Pathways

edited by Ioannis Alexandros Charitos

submission deadline 20 Sep 2026 | Viewed by 216 | Submission Open

Keywords: nanoplastics; microplastics (NMP); toxicology; toxicological impact; human health; human microbiota; metabolome

(This special issue belongs to the Section Molecular Toxicology)

Ameliorating Effect of Natural Bioactive Compounds on Metabolic Diseases and Their Underlying Molecular Mechanisms

edited by Baojun Xu

submission deadline 20 Sep 2026 | Viewed by 215 | Submission Open

Keywords: metabolic diseases; natural bioactive compounds; molecular mechanism; phytochemicals; curing targets; signaling pathway

(This special issue belongs to the Section Bioactives and Nutraceuticals)

The Role of Long Non-Coding RNAs in Cancer Metastasis and Drug Resistance

edited by

Tulasigeri M. Totiger

submission deadline 20 Sep 2026 | Viewed by 208 | Submission Open

Keywords: long non-coding RNAs (lncRNAs); cancer metastasis; drug resistance; epithelial– mesenchymal transition (EMT); tumor microenvironment; chemoresistance mechanisms; RNA-based therapeutics; gene regulation; functional genomics; biomarkers in cancer

(This special issue belongs to the Section Molecular Oncology)

Molecular Diagnosis and Treatment of Oral Cancer

edited by

Evila da Silva Lopes Salles

submission deadline 20 Sep 2026 | Viewed by 207 | Submission Open

Keywords: oral cancer; molecular diagnosis; immunophysiology; tumor microenvironment; drug resistance; oral microbiome

(This special issue belongs to the Section Molecular Oncology)

Nano-Enabled Molecular Strategies Against Oxidative Stress in Human Physiology

edited by

Ali Amer

submission deadline 20 Sep 2026 | Viewed by 199 | Submission Open

Keywords: nanoparticles; oxidative stress; reproductive toxicology; redox signalling pathways; mitochondrial regulation; controlled drug release; antioxidant defence mechanisms; pharmaceutical nanotechnology

(This special issue belongs to the Section Molecular Immunology)

Molecular Developments in the Diagnosis and Treatment of Cerebral Gliomas

edited by

Alejandro N. Santos

submission deadline 20 Sep 2026 | Viewed by 181 | Submission Open

Keywords: glioma; molecular profiling; liquid biopsy; radiogenomics; tumor microenvironment; immuno-therapy; targeted therapy; blood– brain barrier; biomarkers; precision oncology

(This special issue belongs to the Section Molecular Nanoscience)

Obesity and Cancer: Molecular, Cellular and Systemic Mechanisms Underlying Tumor Initiation, Progression and Prognosis

edited by

María Herranz-López

and

María Losada Echeberría

submission deadline 20 Sep 2026 | Viewed by 178 | Submission Open

Keywords: obesity; cancer metabolism; tumor microenvironment; adipose tissue; adipokines; inflammation; insulin resistance; metabolic reprogramming

(This special issue belongs to the Section Molecular Oncology)

RNA Structure and Regulation in Biological Processes

edited by Changrui Lu

submission deadline 20 Sep 2026 | Viewed by 163 | Submission Open

Keywords: RNA structure; RNA three-dimensional conformation; RNA dynamics; RNA chemical modifications; structural biology; RNA– protein interactions; RNA structures in plant disease resistance; viral RNA structure and function; computational structure prediction; host– pathogen interactions

(This special issue belongs to the Section Biochemistry)

Advanced Molecular Research on Diabetes Pharmacology

edited by

Ioanna A. Anastasiou

submission deadline 20 Sep 2026 | Viewed by 119 | Submission Open

Keywords: diabetes; pharmacology; antidiabetic drugs; insulin therapy; SGLT2 inhibitors; GLP-1 receptor agonists; combination therapy; personalized medicine; drug development

(This special issue belongs to the Section Molecular Pharmacology)

Cardiovascular Disease: Molecular Basis and Treatment Strategies

edited by Arrigo Cicero and Federica Fogacci

submission deadline 20 Sep 2026 | Viewed by 99 | Submission Open

Keywords: cardiovascular disease; molecular mechanisms; atherosclerosis; endothelial dysfunction; inflammation; fibrosis; vascular aging; omics; biomarkers; microRNA; extracellular vesicles; precision cardiology; RNA therapeutics; gene therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Immunotherapy in Food Allergy: Toward Precision, Safety and Long-Term Tolerance

edited by

Natalia Ukleja-Sokołowska

submission deadline 20 Sep 2026 | Viewed by 80 | Submission Open

Keywords: food allergy; immunotherapy; immune tolerance; biomarkers

(This special issue belongs to the Section Molecular Immunology)

Research Advances in Circuit Mechanisms of Neurodegenerative Diseases

edited by Abdulkerim Kasim Baltaci

submission deadline 20 Sep 2026 | Viewed by 77 | Submission Open

Keywords: neurodegeneration; synaptic plasticity; zinc homeostasis; oxidative stress; neuroinflammation; Alzheimer’ s disease; Parkinson’ s disease; multiple sclerosis; experimental models

(This special issue belongs to the Section Molecular Neurobiology)

Myosin: Structure, Function and Evolution

edited by Barbara Baryłko and

Joseph P. Albanesi

submission deadline 21 Sep 2026 | Viewed by 356 | Submission Open

Keywords: myosins; actin; molecular motors; organelle trafficking; endocytosis; secretion; membrane tension; RNA transport; force generation; ATPase activity

(This special issue belongs to the Section Macromolecules)

The Role of Natural Products in Treating Human Diseases

edited by Luís R. Silva

submission deadline 25 Sep 2026 | 6 articles | Viewed by 11793 | Submission Open

Keywords: natural products; phytochemicals; biological potential; pharmacological activity; health promoters; chronic diseases

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Nitrogen-Containing Heterocycles and Their Biological Applications

edited by

Stella Manta

submission deadline 25 Sep 2026 | 3 articles | Viewed by 2503 | Submission Open

Keywords: nitrogen-based heterocycles; synthesis; pharmaceuticals; biological activities

(This special issue belongs to the Section Biochemistry)

Gene Mutations in Cancer

edited by

Lucie Benešová

submission deadline 25 Sep 2026 | 1 articles | Viewed by 1971 | Submission Open

Keywords: oncogenetics; somatic mutations; intratumor mutational heterogeneity; tumor mutational burden; circulating tumor DNA; liquid biopsy

(This special issue belongs to the Section Molecular Genetics and Genomics)

Microbial Pathways for Sustainable Bioenergy Production and Environmental Protection

edited by Fiaz Ahmad

submission deadline 25 Sep 2026 | 1 articles | Viewed by 1780 | Submission Open

Keywords: microbial pathways; bioenergy production; bioremediation; metabolic engineering; synthetic biology

(This special issue belongs to the Section Molecular Microbiology)

Research Progress of Natural Products in Metabolic Disorders

edited by Claudia I. Gamboa Gómez and

Laura Jazel Barragán Zúñiga

submission deadline 25 Sep 2026 | Viewed by 503 | Submission Open

Keywords: natural products; metabolic disorders; nutraceuticals; functional foods; metabolic health

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Research on Cannabinoids and Cannabinoid Receptors

edited by Valdemiro Amaro Da Silva Junior

submission deadline 25 Sep 2026 | 2 articles | Viewed by 497 | Submission Open

Keywords: cannabinoids; receptors; endocannabinoidome; degenerative diseases; quality of life

(This special issue belongs to the Section Molecular Pharmacology)

Research on Metal-Based Drugs and Their Mechanisms of Action

edited by Gordana P. Radić

submission deadline 25 Sep 2026 | Viewed by 395 | Submission Open

Keywords: synthesis of metal-containing compounds; characterization; biological activity; mechanisms of action

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Insight into Mesothelioma

edited by

Fabrizio Celesti

submission deadline 25 Sep 2026 | Viewed by 324 | Submission Open

Keywords: mesothelioma; molecular subtypes; molecular landscape; tumor microenvironment; epigenetics; multiomics; therapeutic strategies; immunotherapy; biomarkers; molecular stratification

(This special issue belongs to the Section Molecular Oncology)

Electron or Ion Transport in Electrochemistry

edited by Simone Sanna

submission deadline 25 Sep 2026 | Viewed by 313 | Submission Open

Keywords: solid oxide fuel cells; mixed ionic and electronic conductors; perovskite; fluorite; hydrogen; CO2 reduction; water splitting; energy conversion and storage

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

A Molecular Dynamics Bridge Between Small and Large Scales

edited by

Denis S. Tikhonov

submission deadline 25 Sep 2026 | Viewed by 209 | Submission Open

Keywords: molecular dynamics; non-adiabatic dynamics; sampling; metadynamics; atomistic simulations

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

The Role of Tumor Microenvironment in Cancer Therapy

edited by

Anca-Maria Cimpean

submission deadline 25 Sep 2026 | Viewed by 187 | Submission Open

Keywords: tumor microenvironment; cancer immunotherapy; immune suppression; tumor angiogenesis; tumor metabolism; extracellular matrix

(This special issue belongs to the Section Molecular Oncology)

Breakthroughs in Diagnostic Prediction and Fundamental Therapeutics of Dementia and Movement Disorders, 3rd Edition

edited by

Yasemin M. Akay

submission deadline 25 Sep 2026 | Viewed by 169 | Submission Open

Keywords: Parkinson's disease; dementia with Lewy bodies; Alzheimer's disease; pathogenic protein; biomarker; therapeutic target; drug

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms Regulating Ciliary Motility in Respiratory Health

edited by

Takashi Nakahari

submission deadline 25 Sep 2026 | Viewed by 156 | Submission Open

Keywords: motile cilia; airway; mucociliary clearance; CBF; ciliary waveform; intracellular Cl− ; pH; brain ventricle; obiduct; ciliary transport

(This special issue belongs to the Section Molecular Biology)

Molecular Research on Tea Flavor and Chemistry

edited by

Wei Xu

submission deadline 29 Sep 2026 | Viewed by 335 | Submission Open

Keywords: tea processing; tea chemistry; tea functional components; tea sensory evaluation; tea quality control

(This special issue belongs to the Section Biochemistry)

Molecular Mechanisms in Forensic Pathology

edited by

Vittorio Fineschi

submission deadline 29 Sep 2026 | Viewed by 241 | Submission Open

Keywords: molecular investigation; molecular thanatocronology; molecular autopsy; lesion vitality; molecu-lar forensic toxicology; pharmacogenomics; molecular identification

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Plant Transporters and Tolerance Proteins

edited by Kun Qiao

submission deadline 29 Sep 2026 | Viewed by 205 | Submission Open

Keywords: heavy metal; transporter; antioxidant; ornamental plants and horticulture; ion transport; phytoremediation; biofortification

(This special issue belongs to the Section Molecular Plant Sciences)

Recent Advances in the Role of Diet and Nutrition in Metabolic Diseases

edited by Raquel Rocha

submission deadline 29 Sep 2026 | Viewed by 123 | Submission Open

Keywords: metabolic diseases; type 2 diabetes; obesity; cardiovascular health; metabolic dysfunction– associated liver disease; nutrigenomics; gut microbiome; dietary patterns; precision nutrition; bioactive compounds

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Insights in Neurodegeneration

edited by

Oscar Arias-Carrión

submission deadline 30 Sep 2026 | 7 articles | Viewed by 25062 | Submission Open

Keywords: neurodegeneration; molecular mechanisms; protein aggregation; neuroinflammation; oxidative stress; mitochondrial dysfunction; Alzheimer’ s disease; Parkinson’ s disease; biomarkers; therapeutic targets

(This special issue belongs to the Section Molecular Neurobiology)

Genes and Human Diseases: 3rd Edition

edited by

Mikhail I. Churnosov

submission deadline 30 Sep 2026 | 15 articles | Viewed by 19459 | Submission Open

Keywords: genes; human diseases; genetic-epidemiological studies; genetic factors; susceptibility

(This special issue belongs to the Section Molecular Genetics and Genomics)

Common Mechanisms in Gestational Diabetes, Preeclampsia, and Coronavirus Disease 2019

edited by

Sandor G. Vari

submission deadline 30 Sep 2026 | 7 articles | Viewed by 19120 | Submission Open

Keywords: gestational diabetes; preeclampsia; inflammation; immunoglobulins; glycolisation; platelet aggregation; microvascular thrombosis; coronavirus disease 2019

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Displaying special issue 1751-1800 on page 36 of 65.

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