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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Synthesis Manufacturing and Biomedical Applications of Nanofibers Scaffold submission deadline 20 May 2026 | 1 articles | Viewed by 1263 | Submission Open
Keywords: scaffold manufacturing; nanofibers; 3D platforms; biohybrid scaffolds; biomolecules; functionalization; biomaterials
(This special issue belongs to the Section Molecular Nanoscience)
Advances and Mechanisms in Breast Cancer—2nd Edition
edited by
submission deadline 20 May 2026 | 1 articles | Viewed by 1210 | Submission Open
Keywords: breast cancer; genes and molecular pathways; targets
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Pancreatic Diseases: Molecular Pathology and Therapeutics
edited by
submission deadline 20 May 2026 | 1 articles | Viewed by 1198 | Submission Open
Keywords: pancreatic cancer; acute pancreatitis; chronic pancreatitis; diabetes; inflammation; molecular markers; therapeutic strategies; genetic predispositions; diagnostic tools
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Multifunctional Magnetic Nanoparticles: Synthesis, Properties, and Biomedical Applications submission deadline 20 May 2026 | Viewed by 1194 | Submission Open
Keywords: magnetic nanoparticles; molecular functionalization; magnetocaloric materials; drug delivery systems; molecular imaging; magnetic memory; nanocomposites; nanophosphors; environmental remediation; energy storage materials; magnetic biosensing; biofunctional interfaces
(This special issue belongs to the Section Molecular Nanoscience)
Advancements in Regenerative Medicine Research
edited by
submission deadline 20 May 2026 | 1 articles | Viewed by 1140 | Submission Open
Keywords: regenerative medicine; tissue repair; wound healing; stem cells; cell differentiation; cell signalling; gene regulation; mechanotransduction; precision medicine
(This special issue belongs to the Section Molecular Biology)
Colorectal Cancers: New Approach to Their Pathology, Diagnosis and Therapy
edited by
submission deadline 20 May 2026 | 1 articles | Viewed by 1120 | Submission Open
Keywords: occult blood test; colorectal cancer; colonoscopy; rectal bleeding; abdominal pain; hemicolectomy; novel oncological drugs
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
New Research on Bioactive Natural Products: 2nd Edition submission deadline 20 May 2026 | 1 articles | Viewed by 1106 | Submission Open
Keywords: chronic disorders; bioactives; natural sources; sustainable sources; biomolecular; structure– activity relationship; synergism; health promoting; bio-functional; products; supplements; nutraceuticals; drugs
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Advanced Molecular Research on Pregnancy Complication Mechanisms submission deadline 20 May 2026 | 1 articles | Viewed by 1102 | Submission Open
Keywords: hypertensive pregnancy disorders; gestational diabetes; intrauterine growth restriction; maternal metabolism in pregnancy complications; genetic and epigenetic mechanisms in pregnancy complications; immunology in pregnancy complications
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Gastrointestinal Inflammation: From Pathogenesis to Molecular Diagnosis and Treatment
edited by
submission deadline 20 May 2026 | 1 articles | Viewed by 1022 | Submission Open
Keywords: gastrointestinal tract; inflammation; gastroenteritis; infection; microbiome; mucosal epithelium; immune cells; enteric nervous system
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Analysis on Effector and Regulatory Molecules in Renal Diseases
edited by
submission deadline 20 May 2026 | 1 articles | Viewed by 1016 | Submission Open
Keywords: effector molecules; regulatory molecules; membrane attack complex (MAC); perforin; granzyme; immune complex; neutrophil extracellular traps (NETs); proteolytic enzymes; reactive oxygen species; infection-related glomerulonephritis (IRGN); nephritis-associated plasmin receptor (NAPlr); streptococcal pyrogenic exotoxin B (SPEB); adhesion molecules
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Electrochemical Nanomaterials for Energy and Catalysis
edited by
submission deadline 20 May 2026 | 1 articles | Viewed by 1012 | Submission Open
Keywords: advanced micro- and nanomaterials for electrochemical applications; electrochemical energy storage; electrocatalysis; photoelectrochemical water splitting; electrochemical sensors; supercapacitor; batteries; nanocomposites and functionalized materials; energy storage and conversion application; natural resources-based materials
(This special issue belongs to the Section Molecular Nanoscience)
Antisense Oligonucleotides: Versatile Tools with Broad Applications
edited by
submission deadline 20 May 2026 | 2 articles | Viewed by 987 | Submission Open
Keywords: antisense oligonucleotide; RNase H; splice switching; exon skipping; therapeutics; pesticide
(This special issue belongs to the Section Molecular Biology)
Exploring Rare Diseases: Genetic, Genomic and Metabolomic Advances: 2nd Edition
edited by and
submission deadline 20 May 2026 | 1 articles | Viewed by 973 | Submission Open
Keywords: rare diseases; genotype– phenotype analyses; NGS; mass spectrometry; biomarker discovery; molecular targeted therapy
(This special issue belongs to the Section Molecular Genetics and Genomics)
Natural and Synthetic Modified Nucleic Acids: Their Properties, Functions and Applications
edited by
submission deadline 20 May 2026 | 2 articles | Viewed by 876 | Submission Open
Keywords: DNA; RNA; nucleic acid analogues; modified nucleosides; modified nucleosides identification techniques; nucleoside modifying enzymes; gene therapy; therapeutic nucleic acids; biomedical applications; drug delivery
(This special issue belongs to the Section Molecular Biology)
Recent Advances in the Structure, Biological Activity and Structure–Activity Relationship of Polysaccharides submission deadline 20 May 2026 | 2 articles | Viewed by 867 | Submission Open
Keywords: natural polysaccharides; phytochemicals; nutraceuticals; structure– activity relationship; anticancer potential; immunomodulation
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Eukaryotic DNA Replication—from Bench to Bedside
edited by Heinz-Peter Nasheuer
submission deadline 20 May 2026 | 1 articles | Viewed by 833 | Submission Open
Keywords: genome stability; cell cycle; DNA replication; chromatin replication; replication origins— selection; licensing and firing; replication forks— smoothly progressing and under stress; role of DNA replication in cancer and other human diseases; disease treatment opportunities
(This special issue belongs to the Section Molecular Genetics and Genomics)
The Role of Extracellular Vesicles in Disease and Therapeutic Applications
edited by Sunyoung Park
submission deadline 20 May 2026 | 1 articles | Viewed by 795 | Submission Open
Keywords: extracellular vesicles (EVs); disease biomarkers; EV-based therapeutics; cancer diagnosis; drug delivery; immune modulation; regenerative medicine
(This special issue belongs to the Section Molecular Biology)
Synthesis and Application of Natural and Inspired-Natural Products
edited by Mauro de Nisco
submission deadline 20 May 2026 | 1 articles | Viewed by 770 | Submission Open
Keywords: natural products; natural substances; derivative; synthesis; application
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Unraveling the Molecular Landscape of Primary Brain Tumors
edited by , Francesco Pasqualetti and Tamara Ius
submission deadline 20 May 2026 | Viewed by 741 | Submission Open
Keywords: primary brain tumors; molecular oncology; glioma; glioblastoma; biomarkers; targeted therapy; epigenetics; tumor microenvironment; genomic profiling; translational research
(This special issue belongs to the Section Molecular Neurobiology)
Emerging Roles of the Gut-Brain Axis (GBA) in Health and Disease
edited by Vinata Vedam-Mai
submission deadline 20 May 2026 | 1 articles | Viewed by 741 | Submission Open
Keywords: gut– brain axis; gut microbiota; brain function; diagnostic tools
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in the Translational Preclinical Research
edited by
submission deadline 20 May 2026 | 1 articles | Viewed by 686 | Submission Open
Keywords: translational preclinical research; drug discovery; cancer therapies; in vitro and in vivo experiments; biological mechanisms
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Survival of the Fittest: Physiological Adaptations of Insects in Hostile Environments submission deadline 20 May 2026 | Viewed by 665 | Submission Open
Keywords: insect adaptation; temperature tolerance; insect physiology; detoxification; symbiosis and stress tolerance mechanisms
(This special issue belongs to the Section Molecular Biology)
Computational Approaches in Biomedicine: Innovations and Insights
edited by
submission deadline 20 May 2026 | Viewed by 596 | Submission Open
Keywords: computational biomedicine; artificial intelligence; machine learning; omic technologies; system biology; medical imaging; structural biology; drug discovery
(This special issue belongs to the Section Molecular Informatics)
Lipoproteins—Opportunities for the Development of Nanotherapeutics in Chronic Disease
edited by
submission deadline 20 May 2026 | Viewed by 595 | Submission Open
Keywords: lipoproteins; LDL; HDL; nanotherapeutics; chronic disease; targeted therapy; drug delivery
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
New Molecular Insights into Antibacterial Material
edited by Rahela Carpa
submission deadline 20 May 2026 | 1 articles | Viewed by 588 | Submission Open
Keywords: antimicrobial resistance; nanoparticles; biopolymers; antimicrobial peptides; antimicrobial materials
(This special issue belongs to the Section Materials Science)
Repair Mechanisms of Stem Cells submission deadline 20 May 2026 | Viewed by 588 | Submission Open
Keywords: stem cell biology; stem cells; stem cell therapy; tissue regeneration
(This special issue belongs to the Section Biochemistry)
Chessboard: How Plants and Insects Outsmart Each Other
edited by
submission deadline 20 May 2026 | 1 articles | Viewed by 569 | Submission Open
Keywords: acarology; biotic stress; entomology nitric oxide; oxidative stress; phytopathology; reactive nitrogen species; reactive oxygen species
(This special issue belongs to the Section Molecular Plant Sciences)
The Role of Transcription Factors in Antioxidant Pathways
edited by
submission deadline 20 May 2026 | 1 articles | Viewed by 532 | Submission Open
Keywords: transcription factor; oxidative stress; NRF1/2; NRF3; NFkB; P53; antioxidant-response elements; neurologial diseases; metabolic diseases; cancer
(This special issue belongs to the Section Molecular Biology)
New Biomarkers in Pancreatic Diseases
edited by and
submission deadline 20 May 2026 | Viewed by 528 | Submission Open
Keywords: pancreatic disease; pancreatic cancer; pancreatitis; biomarker; RNA
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Current Research in Membrane Transporters, Channels, and Receptors
edited by Ivana Vrhovac Madunic
submission deadline 20 May 2026 | Viewed by 526 | Submission Open
Keywords: membrane transporters; cell membrane; transmembrane proteins; glucose transport; ion channels; cellular receptors; signal tranduction; pathophysiology; diabetes; aging
(This special issue belongs to the Section Molecular Biology)
Cell Death in Human Diseases: Mechanisms, Biomarkers and Therapeutic Opportunities
edited by
submission deadline 20 May 2026 | Viewed by 507 | Submission Open
Keywords: cell death; apoptosis; necroptosis; ferroptosis; pyroptosis; human disease; biomarkers
(This special issue belongs to the Section Molecular Biology)
X-Linked Disorders: Epigenetic and Environmental Modulation of Phenotypes
edited by Yoram Chaiter and
submission deadline 20 May 2026 | Viewed by 502 | Submission Open
Keywords: X-linked disorders; epigenetics; environmental factors; gene expression; clinical manifestations
(This special issue belongs to the Section Molecular Genetics and Genomics)
Interfaces for the Impact of Magnetic Pulses or EMF in Molecular Biology
edited by Richard H. W. Funk
submission deadline 20 May 2026 | Viewed by 427 | Submission Open
Keywords: electromagnetic treatment; magnetic pulses; biological interface; cell biology; molecular biology; signaling cascades; clinical treatment; monitoring; sensors
(This special issue belongs to the Section Molecular Biophysics)
Molecular Mechanisms of Skeletal Muscle Adaptation
edited by
submission deadline 20 May 2026 | 1 articles | Viewed by 427 | Submission Open
Keywords: skeletal muscle; adaptive responses; muscle physiology; genomics; transcriptomics; proteomics; molecular mechanisms
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Research in Ocular Inflammation and Infection
edited by
submission deadline 20 May 2026 | 1 articles | Viewed by 425 | Submission Open
Keywords: ocular infections; uveitis; choroiditis; masquerade syndrome; pseudo-uveitis; intraocular lymphoma; retinal dystrophy; ocular inflammation; neuroinflammation; immunotherapy-induced uveitis; autoimmune eye diseases; sarcoidosis; OCT; indocyanine green angiography
(This special issue belongs to the Section Molecular Immunology)
Advances in Biological Breeding and Molecular Biology of Tropical Crops
edited by Yongzan Wei
submission deadline 20 May 2026 | 1 articles | Viewed by 399 | Submission Open
Keywords: tropical crops; biological breeding; tropical fruit; molecular biology; gene editing; transcrip-tional regulation; genomics
(This special issue belongs to the Section Molecular Plant Sciences)
Current Advance in Infectious and Inflammatory Diseases submission deadline 20 May 2026 | 1 articles | Viewed by 392 | Submission Open
Keywords: inflammatory diseases; infectious diseases; host– pathogen interactions; antimicrobial resistance; immune modulation; cytokine signaling
(This special issue belongs to the Section Molecular Microbiology)
Pathogenesis and Treatment of Prostate Cancer submission deadline 20 May 2026 | Viewed by 366 | Submission Open
Keywords: prostate cancer; pathogenesis; genetic mutations; target therapy; surgery; radiation therapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Understanding Respiratory Virus–Host Interactions
edited by Kun Li
submission deadline 20 May 2026 | Viewed by 346 | Submission Open
Keywords: respiratory viruses; virus– host interactions; molecular mechanisms; viral replication; host– immune response; molecular pathogenesis; molecular signaling; antiviral strategies
(This special issue belongs to the Section Molecular Microbiology)
Advances in Endoplasmic Reticulum Stress and Apoptosis—Second Edition submission deadline 20 May 2026 | 1 articles | Viewed by 339 | Submission Open
Keywords: ER stress; apoptosis initiated by ER stress; cellular survival; redox homeostasis of ER; autophagy initiated by ER stress; cell death pathways initiated by ER stress
(This special issue belongs to the Section Biochemistry)
Advanced Research in Nanophotonics and Biophotonics
edited by
submission deadline 20 May 2026 | Viewed by 331 | Submission Open
Keywords: biophotonics; spectroscopy; light scattering; Raman/FTIR; cancer; Alzheimer's and Parkinson’ s diseases; nanophotonics; plasmonics; nano-biophotonics
(This special issue belongs to the Section Molecular Nanoscience)
Recent Advances in Neurofibromatosis Type 1: From Molecular Insights to Novel Therapies
edited by László Szabó and
submission deadline 20 May 2026 | Viewed by 329 | Submission Open
Keywords: neurofibromatosis type 1; genotype– phenotype analyses; molecular pathogenesis; next-generation sequencing (NGS); molecular targeted therapy; MEK inhibitors; imaging studies
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Insights into Antimicrobial Agents: Mechanisms and Applications submission deadline 20 May 2026 | Viewed by 311 | Submission Open
Keywords: antimicrobial compounds; antibacterial activity; antibiotic resistance; pathogen-tailored therapeutic targeting; novel antimicrobials; molecular aspects of the mechanisms of action of antibacterial substances; effectiveness of antibacterial substances
(This special issue belongs to the Section Biochemistry)
Advanced Research on Comparative Reproductive Physiology submission deadline 20 May 2026 | Viewed by 302 | Submission Open
Keywords: andrology; sperm; oocyte; gamete interactions; reproductive morphology; reproductive endocrinology; omics; epigenetics; pregnancy; all animal species
(This special issue belongs to the Section Molecular Biology)
Unraveling Neuroimmune Disorders: From Pathogenic Pathways to Biomarker-Driven Precision Medicine
edited by
submission deadline 20 May 2026 | Viewed by 279 | Submission Open
Keywords: innate immunity; adaptive immunity; inflammation; autoantibodies; peptides; cytokines; receptors; leukocytes; extracellular vesicles; signal transduction; apoptosis
(This special issue belongs to the Section Molecular Immunology)
Molecular Advances in Primary Colorectal Cancer and Liver Metastases
edited by Alexandros E. Giakoustidis
submission deadline 20 May 2026 | Viewed by 276 | Submission Open
Keywords: colorectal cancer; metastasis; treatment; management; screening; genetic alterations; epigenetic alterations; genomics; epigenomics; methylation; liver-directed therapy; radiation; immunotherapy; peritoneal carcinomatosis; monotherapy; chemotherapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Targeted Protein Degradation: From Molecular Mechanisms to Therapeutic Applications
edited by
submission deadline 20 May 2026 | Viewed by 258 | Submission Open
Keywords: targeted protein degradation; ubiquitin– proteasome system; PROTAC; drug design; medicinal chemistry
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Mechanisms Linked to Exercise
edited by Igor Zubrzycki
submission deadline 20 May 2026 | Viewed by 256 | Submission Open
Keywords: molecular mechanisms; exercise adaptations; translational health
(This special issue belongs to the Section Molecular Biology)
Latest Molecular Advances in Prostate Cancer
edited by Rejane Maira Góes
submission deadline 20 May 2026 | Viewed by 249 | Submission Open
Keywords: prostate cancer; androgen signaling; metabolic reprogramming; tumor microenvironment; inflammation; immunotherapy; chemoprotection; phytotherapy
(This special issue belongs to the Section Molecular Oncology)
Molecular Application of Hyaluronan in Tissue Healing submission deadline 20 May 2026 | Viewed by 242 | Submission Open
Keywords: wound healing; inflammation; remodeling; chronic wound; wound dressing; scar tissue; sound tissue; biomarkers; chemical modification; crosslinked; biopolymer; biological activity
(This special issue belongs to the Section Macromolecules)
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