Latest Molecular Advances in Prostate Cancer
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 44
Special Issue Editor
Interests: prostate; biology of reproduction; metabolic disturbances; endocrine disruptors; leydig cell; spermatogenesis; experimental carcinogenesis; cell proliferations; apoptosis
Special Issue Information
Dear Colleagues,
Prostate cancer is a heterogeneous disease that can exhibit indolent or aggressive behavior and that represents a complex global health burden. While tumors that are responsive to therapy that target androgen receptors have good outcomes, they can evolve to reach an androgen-independent state, also known as being castration-resistant. In this case, there are few therapeutic strategies, and the molecular changes that occur along with disease progression have not yet been fully elucidated. For decades, researchers have worked to increase our understanding of known mechanisms, find new molecular targets, and propose innovative therapies to change this scenario, but prostate cancer remains among the leading cause of death worldwide.
For this Special Issue, we invite submissions that address long-lasting questions in this field, open up new therapeutic possibilities, and shed light on new molecular mechanisms. We encourage submissions on topics such as inflammation and immunotherapy, metabolic reprogramming, androgen signaling, chemoprotection, metastasis mechanisms, and the impact of diet and xenobiotics on disease progression and initiation. Therefore, we welcome perspectives, reviews, and full-length articles to fill in relevant gaps in the literature on prostate cancer mechanisms and possible therapeutic targets. However, since IJMS is a journal of molecular science, pure clinical studies will not be accepted.
This Special Issue will be supervised by Dr. Rejane Maira Góes and assisted by Dr. Guilherme Henrique Tamarindo. Dr. Rejane Góes is a Full Professor at the Department of Biological Sciences of Institute of Biosciences, Humanities and Exact Sciences at São Paulo State University (IBILCE/UNESP). She holds a Ph.D. in Cellular and Molecular Biology from University of São Paulo (USP). Her research focuses on cellular and physiological changes in the male reproductive system under metabolic disorders, hormonal imbalances, aging, and carcinogen exposure. Dr. Guilherme Tamarindo is a Researcher at the Brazilian Biosciences National Laboratory (LNBio) at the Brazilian Center for Research in Energy and Materials (CNPEM). He holds a Ph.D. in Structural and Cellular Biology from the State University of Campinas (UNICAMP). His research interests include metabolic reprogramming in cancer, lipid biology, and the association of immune cells with cancer progression.
Dr. Rejane Maira Góes
Guest Editor
Manuscript Submission Information
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Keywords
- prostate cancer
- androgen signaling
- metabolic reprogramming
- tumor microenvironment
- inflammation
- immunotherapy
- chemoprotection
- phytotherapy
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