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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Research Advances in Antibiotic Resistance

edited by

José Pascual Abad

and

Irma Marín

submission deadline 20 Apr 2026 | 2 articles | Viewed by 1960 | Submission Open

Keywords: antibiotic resistance; resistant pathogenic microorganisms; One Health; prevalence of antibiotic-resistant microorganisms; multidrug resistance; antibiotic resistance levels; alternative anti-infectious strategies and compounds; antibiotic-resistant genes; mechanisms of antimicrobial resistance

(This special issue belongs to the Section Molecular Microbiology)

Multiple Sclerosis: Molecular Basis and New Therapy

edited by Vito A. G. Ricigliano

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1958 | Submission Open

Keywords: multiple sclerosis; inflammation; microglia; Epstein– Barr virus; neurodegeneration; remyelination; therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Biomarker Discovery in Oral Diseases: Integrating Connected Health and Digital Biomarkers for Advanced Diagnostics and Personalized Care

edited by

Shahnawaz Khijmatgar

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1947 | Submission Open

Keywords: oral diseases; biomarker; proteomics; metabolomics

(This special issue belongs to the Section Molecular Biology)

Exploring Amazon Bioactives: Novel Anti-Pathogen Therapeutics and Pharmaceutical Breakthroughs

edited by Marta Chagas Monteiro,

Nélio Teixeira Machado

and Pedro Roosevelt Romão

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1893 | Submission Open

Keywords: waste biomass; thermochemical processes; bio-oils; phenolic compounds; anti-inflammatory actions; antiviral mechanisms; cancer; cytokine/chemokine regulation; inflammatory conditions/diseases; innate immunity; immune response; immunomodulatory and anti-infective effects; immunomodulation; immunotoxicology; medicinal chemistry; neglected tropical diseases; parasitic disease; purinergic signaling

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Applications of Mass Spectrometry in the Analysis of Bioactive and Plant Organic Compounds

edited by

Marisabel Mecca

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1870 | Submission Open

Keywords: mass spectrometry; VOCs; bioactive compounds; plant organic compounds; pharmaceutical research; metabolites

(This special issue belongs to the Section Biochemistry)

Biochemical Advancements in Filler Technology and Their Impact on Tissue Engineering

edited by Samuel J. Lin

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1862 | Submission Open

Keywords: biochemical filler technology; tissue regeneration; bioactive materials; injectable scaffolds; molecular signaling in tissue engineering; biomaterials for soft tissue repair; filler– cell interactions; regenerative esthetics

(This special issue belongs to the Section Biochemistry)

Pathogenic Proteins in Neurodegenerative Diseases: From Pathogenesis to Therapeutic Innovations

edited by

Minseok Song

and

Nidhi Puranik

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1857 | Submission Open

Keywords: Alzheimer’ s disease; Parkinson’ s disease; amyotrophic lateral sclerosis; frontotemporal dementia; lewy bodies dementia; amyloid β -protein; τ -protein; α -synuclein; TDP-43; neurotransmitter; neuropeptide; protein misfolding; protein Homeostasis; neuroinflammatory proteins; post-translational modifications

(This special issue belongs to the Section Molecular Neurobiology)

Transforming in Cancer Therapy: Advances in Immunotherapy and Tyrosine Kinase Inhibitors

edited by

Walid Shalata

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1787 | Submission Open

Keywords: tyrosine kinase inhibitors; immunotherapy; monoclonal antibodies; CAR-T cells

(This special issue belongs to the Section Molecular Oncology)

Molecular Perspectives on the Synthesis and Application of Hydrogel Materials

edited by

Jieping Fan

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1776 | Submission Open

Keywords: hydrogels; molecular basis; polymeric networks; supermolecular chemistry; three-dimensional structure; mechanical strength; rheologic properties; biomaterial

(This special issue belongs to the Section Materials Science)

Heat Shock Proteins (HSPs): Biological Functions and Mechanisms of Actions

edited by

Soumya Patnaik

and

Gregory Blatch

submission deadline 20 Apr 2026 | 2 articles | Viewed by 1759 | Submission Open

Keywords: heat shock proteins; apoptosis; immune cell activation; stress responses; misfolded proteins; cellular chaperones; cell signaling

(This special issue belongs to the Section Biochemistry)

In Silico Approaches to Drug Design and Discovery

edited by

Alejandro Speck-Planche

submission deadline 20 Apr 2026 | 2 articles | Viewed by 1756 | Submission Open

Keywords: chemoinformatics; computational de novo design and generative AI methods; machine learning; deep learning; molecular modeling; pharmacophore modeling; molecular docking; molecular dynamics; QSAR/QSPR; virtual screening

(This special issue belongs to the Section Molecular Informatics)

Accelerating Therapeutic Innovation: Advances in Computer-Aided Drug Discovery

edited by Pietro Delre and

Antonio Lavecchia

submission deadline 20 Apr 2026 | 2 articles | Viewed by 1737 | Submission Open

Keywords: CADD; drug discovery; machine learning; virtual screening; drug-target interaction

(This special issue belongs to the Section Molecular Informatics)

Interplay of Metabolism and Inflammation in Gastrointestinal Disease

edited by Marios N. Papadakis and

Stavros P. Papadakos

submission deadline 20 Apr 2026 | Viewed by 1733 | Submission Open

Keywords: gastrointestinal diseases; inflammation; metabolic dysregulation; metabolic processes

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Functional Polymeric Materials: From Synthesis to Applications: 2nd Edition

edited by

Marta Fernández-García

and

Alexandra Muñoz-Bonilla

submission deadline 20 Apr 2026 | 2 articles | Viewed by 1726 | Submission Open

Keywords: natural polymers; bio-based polymers; block copolymers; micelles; polymer chemistry; (hydro)gels; (bio)applications; degradability

(This special issue belongs to the Section Materials Science)

New Insights into Lactoferrin: 2nd Edition

edited by

Antimo Cutone

and

Giovanni Musci

submission deadline 20 Apr 2026 | 2 articles | Viewed by 1723 | Submission Open

Keywords: lactoferrin; lactoferrin structure; lactoferrin functions; infection; inflammation; iron homeostasis; oxidative stress; lactoferrin bioavailability

(This special issue belongs to the Section Molecular Immunology)

Application of Mass Spectrometry and Chromatography in Drug Monitoring

edited by Carsten Müller

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1716 | Submission Open

Keywords: therapeutic drug monitoring; method validation; pharmacometrics; pediatric clinical pharmacology; laboratory developed tests; clinical mass spectrometry; functional tests; isobars; triple quad mass spectrometry; HR-MS; biomarker; drugs of abuse; therapeutic drugs; metabolites

(This special issue belongs to the Section Biochemistry)

Advances in the Purinergic System

edited by Margarete Dulce Bagatini

submission deadline 20 Apr 2026 | 2 articles | Viewed by 1678 | Submission Open

Keywords: purinergic system; receptors; ectonucleotidases; CD39; CD73; purinergic signaling

(This special issue belongs to the Section Biochemistry)

Peptide and Protein Drugs Against Infectious Diseases and Allergic Diseases

edited by

Xiumin Wang

submission deadline 20 Apr 2026 | 2 articles | Viewed by 1613 | Submission Open

Keywords: peptide and protein drugs; infectious diseases; allergic diseases; hormones; antimicrobial peptides; neuropeptides; cell-penetrating peptides; enzyme inhibitors; vaccines; antibodies

(This special issue belongs to the Section Molecular Pharmacology)

Forest Tree Genetics, Breeding and Environmental Adaption

edited by

Jingli Yang

and

Huiyu Li

submission deadline 20 Apr 2026 | 2 articles | Viewed by 1608 | Submission Open

Keywords: forest trees; genetic breeding; biotic stress; abiotic stress; tree physiology; gene regulation; genetic engineering

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Biology and the Genetic Breeding of Aquatic Animals: Breakthroughs and Challenges (2nd Edition)

edited by

Hongyan Xu

submission deadline 20 Apr 2026 | 4 articles | Viewed by 1601 | Submission Open

Keywords: transgenic; genetic breeding; omics; gene expression and regulation; aquatic animals

(This special issue belongs to the Section Molecular Biology)

Functional Proteomics: Insights from Biomedical Applications and Beyond

edited by

Elva Morretta

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1580 | Submission Open

Keywords: functional proteomics; drug discovery; biomedicine; biomarker identification; protein molecular functions; pathway investigation

(This special issue belongs to the Section Molecular Immunology)

New Perspectives on Prostate Cancer Occurrence, Diagnosis, and Treatment

edited by

Michele Marchioni

and

Luigi Schips

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1571 | Submission Open

Keywords: prostate cancer; biomarker; diagnosis; treatment

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Pathology and Next-Generation Biomarkers in Nephrology

edited by

Marijn Speeckaert

submission deadline 20 Apr 2026 | 2 articles | Viewed by 1541 | Submission Open

Keywords: nephrology; genetic mutations; epigenetics; next-generation biomarkers; proteomics; metabolomics; single-cell sequencing; spatial transcriptomics; liquid biopsy; cfDNA; exosomes; microRNAs

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Regulatory Mechanisms in the Hypoxic Environment

edited by Irene Filippi

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1539 | Submission Open

Keywords: hypoxia; hypoxia-inducible factors (HIFs); angiogenesis; metabolic adaptation; autophagy; cell survival; chronic obstructive pulmonary disease (COPD); cancer

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Recent Progress in Extracellular Vesicles

edited by

Regina Golan-Gerstl

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1535 | Submission Open

Keywords: extracellular vesicles (EVs); macrovesicles; exosomes; cell– cell comunication

(This special issue belongs to the Section Molecular Biology)

Plants Redox Biology

edited by

Xin Li

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1533 | Submission Open

Keywords: plant– environment interaction; stress physiology; plant redox signaling; plant hormones; plant– pathogen interaction; reactive oxygen species (ROS); reactive nitrogen species (RNS); ascorbate; flavonoid; glutathione

(This special issue belongs to the Section Molecular Plant Sciences)

Trace Elements, Metals and Bioactive Compounds: Homeostasis and Metabolic Impairment

edited by

Graziantonio Lauria

and

Rosita Curcio

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1522 | Submission Open

Keywords: trace elements; bioactive compounds; metals; human health; human diseases

(This special issue belongs to the Section Biochemistry)

Updates and Advances in the Field of Glioblastomas: Mechanisms, Microenvironment and Treatments

edited by

Samantha Epistolio

submission deadline 20 Apr 2026 | 2 articles | Viewed by 1512 | Submission Open

Keywords: GBM; molecular classification; pediatric diffuse gliomas; signaling pathways in GBMs; recurrent gliomas; midbrain gliomas; immunotherapy; targeted therapies for GBMs

(This special issue belongs to the Section Molecular Oncology)

Molecular Studies of Muscle Contraction

edited by

Massimo Reconditi

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1503 | Submission Open

Keywords: muscle contraction; actin; myosin; thin and thick filament; cytoskeletal anchoring protein

(This special issue belongs to the Section Molecular Biophysics)

Selected Papers from the 13th International Conference on Carbonic Anhydrases and Other Research

edited by

Claudiu T. Supuran

and

Óscar López

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1475 | Submission Open

Keywords: metalloenzymes; carbonic anhydrase; inhibitors; activators; pharmacology; SLC-0111; anticancer agents

(This special issue belongs to the Section Biochemistry)

Research on Plant-Microbe Interactions

edited by Lin Chen

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1410 | Submission Open

Keywords: beneficial microbes; rhizosphere; phyllosphere; endosphere; colonization; microbiome; root exudates; communication; secondary metabolites; plant immunity; environmental stress; resistance to plant disease

(This special issue belongs to the Section Molecular Plant Sciences)

Plant Physiology and Molecular Nutrition: 2nd Edition

edited by

Shu Yuan

and

Guijie Lei

submission deadline 20 Apr 2026 | 2 articles | Viewed by 1380 | Submission Open

Keywords: plant nutritional physiology; nutrient signaling; phytohormones; gene regulation network; environment and nutrition crosstalk

(This special issue belongs to the Section Molecular Plant Sciences)

Innovative Therapeutic Approaches to Endocrine Disorders

edited by

Gilberta Giacchetti

and

Emanuele-Salvatore Scarpa

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1373 | Submission Open

Keywords: endocrine disorders; osteoporosis; diabetes; obesity; synthetic drugs; nutraceuticals; biomarkers

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Advances in Neuroimaging

edited by

Chrissa Sioka

submission deadline 20 Apr 2026 | 2 articles | Viewed by 1327 | Submission Open

Keywords: positron emission tomography pulmonary immunology; single photon emission computed tomography; artificial intelligence; neuro-oncology imaging; neurodegenerative disorders imaging; molecular neuroimaging

(This special issue belongs to the Section Molecular Neurobiology)

The Latest Molecular Research on Renal Disease

edited by Niels Henrik Buus and Marco Eijken

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1280 | Submission Open

Keywords: renal disease; chronic kidney disease; renal regeneration; kidney injury

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Liver Diseases: From Pathophysiology to Novel Therapeutic Approaches

edited by Clare Selden

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1272 | Submission Open

Keywords: liver disease molecular mechanisms treatments for liver disease somatic cell therapy; ATMP medical device molecular approaches; molecular signatures; RNA therapies; “ omics” for liver disease pathobiology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Interplay Between Blood Cells and Cytokines

edited by

Mats B. Eriksson

and

Anders O. Larsson

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1252 | Submission Open

Keywords: blood cells; communication; cytokine; erythrocyte; immunology; inflammation; interplay; leucocyte; platelet; network

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Environmental Influences on Cellular Responses

edited by

Marcus Krüger

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1226 | Submission Open

Keywords: cell/environment interaction; cell signaling; mechanobiology; photobiology; thermobiology; enviromics; cell-cell communication; cell-cell interaction

(This special issue belongs to the Section Molecular Biology)

Red Blood Cell Dysfunction and Hemodynamic Changes in Inflammation, Infection and Metabolic Disease

edited by Janette Bester

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1220 | Submission Open

Keywords: red blood cell; inflammation; infection; metabolic disease; hemodynamics

(This special issue belongs to the Section Molecular Biology)

Molecular Advances in Macroporous, Mesoporous, and Microporous Materials

edited by

Magdalena Laskowska

submission deadline 20 Apr 2026 | 2 articles | Viewed by 1216 | Submission Open

Keywords: functional materials; nanomaterials; nanostructures; molecular systems; porous materials

(This special issue belongs to the Section Materials Science)

Advances in Metabolomics for Animal Health and Nutrition

edited by

María Dolores Llobat Bordes

and

Pablo Jesús Marín-García

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1179 | Submission Open

Keywords: metabolomics; animal health; animal nutrition; biomarkers; mass spectrometry; NMR spectroscopy; precision nutrition

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Stem Cell Biology & Regenerative Medicine—2nd Edition

edited by

Rivka Ofir

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1170 | Submission Open

Keywords: hiPSC; hES; Crispr; BBB; disease in a dish; neuro-regeneration; pain reliever; scaffold

(This special issue belongs to the Section Molecular Biology)

Genomics, Genetics, and the Future of Fruit Improvement

edited by Zoe Hilioti

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1146 | Submission Open

Keywords: fruit traits; genetics; genetic diversity; omics; new breeding techniques; fruit quality; shelf life

(This special issue belongs to the Section Molecular Plant Sciences)

Future Challenges and Innovation in Gynecological Oncology

edited by

Alejandro Herreros-Pomares

submission deadline 20 Apr 2026 | 2 articles | Viewed by 1144 | Submission Open

Keywords: gynecologic oncology; molecular biomarkers; personalized medicine; ovarian cancer; immunotherapy; tumor microenvironment; drug resistance; translational research

(This special issue belongs to the Section Molecular Oncology)

Collagen and Its Derivatives in Tissue Engineering

edited by

István Hornyák

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1127 | Submission Open

Keywords: collagen derivatives; tissue engineering; in vitro experiments; in vivo investigations; material degradation

(This special issue belongs to the Section Biochemistry)

Fiber Plants: Genetics and Genomics, Molecular Mechanisms and Potential Applications—Novel Materials, Functional Foods and Beyond

edited by

Jian Zhang

and

Michael Deyholos

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1120 | Submission Open

Keywords: fiber plant; genetics; genomics; bioactive products; natural fibers; fatty acids; medical products; environmental and ecological effects of fiber plants

(This special issue belongs to the Section Molecular Plant Sciences)

Emerging Topics in Macromolecular Crystallography

edited by

Zhongzhou Chen

and

Giuseppe Zanotti

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1119 | Submission Open

Keywords: macromolecular crystallography; structural biology; artificial intelligence; structure determination; molecular mechanism; functions; drug discovery; protein; nucleic acid; carbohydrates

(This special issue belongs to the Section Macromolecules)

Current Advances in the Pathophysiology and Treatment of Multiple Sclerosis and Related Disorders

edited by Natalia Szejko and

Sara Samadzadeh

submission deadline 20 Apr 2026 | Viewed by 1105 | Submission Open

Keywords: multiple sclerosis; MS; central nervous system; pathophysiology; immunological system

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Lung Cancer: From Molecular Mechanisms to Novel Therapeutics: 2nd Edition

edited by

Mariacarmela Santarpia

and

Giulia Pasello

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1094 | Submission Open

Keywords: lung cancer; oncogene; targeted therapy; immunotherapy; predictive biomarkers; liquid biopsy

(This special issue belongs to the Section Molecular Oncology)

Molecular Insights on Myogenic Progenitors: Regulation of Differentiation

edited by

James M. Holaska

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1093 | Submission Open

Keywords: myogenic progenitors; skeletal muscle; muscle regeneration; myogenesis

(This special issue belongs to the Section Molecular Biology)

Displaying special issue 2801-2850 on page 57 of 69.

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