New Perspectives on Prostate Cancer Occurrence, Diagnosis, and Treatment
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 20 November 2025 | Viewed by 1188
Special Issue Editors
Interests: kidney disease; kidney damage; kidney inflammation
Special Issues, Collections and Topics in MDPI journals
Interests: prostate cancer; urology; kidney cancer; prostate; urologic oncology; endourology; urolithiasis; robotics & minimally invasive urology; surgical oncology; BPH
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear colleagues,
Prostate cancer is a leading malignancy in men, and recent molecular advances are transforming our understanding of its occurrence, diagnosis, and treatment. Key genetic alterations, such as BRCA1/2, PTEN, and TP53 mutations, as well as the TMPRSS2-ERG fusion, are now recognized as drivers of prostate cancer progression. Molecular biomarkers, including circulating tumor cells and DNA methylation patterns, are enhancing diagnostic precision and risk stratification.
In treatment, personalized medicine is becoming a reality with targeted therapies, such as PARP inhibitors, for BRCA-mutated tumors. Immunotherapies, encompassing immune checkpoint inhibitors and CAR-T cells, are also gaining attention, although prostate cancer's immunologically "cold" nature poses challenges. Epigenetic modifications are another frontier, with therapies aimed at reversing these changes showing promise.
This Special Issue welcomes contributions that focus on molecular insights into prostate cancer to advance diagnosis and treatment strategies.
Dr. Michele Marchioni
Prof. Dr. Luigi Schips
Guest Editors
Manuscript Submission Information
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Keywords
- prostate cancer
- biomarker
- diagnosis
- treatment
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