Advances in Metabolomics for Animal Health and Nutrition

Dear Colleagues,

The growing application of metabolomics in animal science is reshaping our ability to understand and optimize animal health, nutrition, and production systems. This Special Issue, Advances in Metabolomics for Animal Health and Nutrition, compiles innovative research and comprehensive reviews that showcase the power of metabolomic technologies in investigating biochemical processes in animals. Metabolomics, by enabling high-throughput and detailed profiling of small-molecule metabolites, provides unique insights into the physiological and metabolic responses of animals to dietary inputs, disease conditions, environmental stressors, and microbiome dynamics.

The contributions to this Special Issue span a wide range of animal species, including livestock, poultry, aquaculture species, and companion animals. Featured studies explore biomarker discovery for early disease detection, evaluation of nutrient utilization efficiency, assessment of metabolic responses to feed additives, and elucidation of host–microbiome interactions. Advanced analytical platforms such as mass spectrometry and nuclear magnetic resonance spectroscopy are leveraged alongside multivariate data analysis and systems biology approaches to interpret complex metabolic signatures.

Furthermore, this Special Issue emphasizes the integration of metabolomics with other omics disciplines, including genomics, transcriptomics, and proteomics, to provide a more comprehensive understanding of animal biology. Such integrative approaches are crucial for developing precision nutrition strategies, improving animal welfare, and promoting sustainable animal production.

Together, the articles in this Special Issue illustrate the significant role of metabolomics as both a diagnostic and predictive tool in animal health and nutrition. By bridging fundamental metabolic research with practical applications, this collection highlights current achievements and points toward future directions in the field. The advances presented here will support the development of innovative, evidence-based practices that benefit animal productivity, health management, and environmental sustainability in modern agricultural and veterinary contexts.

Prof. Dr. María Dolores Llobat Bordes
Prof. Dr. Pablo Jesús Marín-García
Guest Editors

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