Molecular Pathology and Next-Generation Biomarkers in Nephrology

Dear Colleagues,

This Special Issue focuses on the fast-evolving world of molecular pathology and next-generation biomarkers in nephrology. CKD, AKI, glomerular disease, and transplant complications are significant clinical challenges that are often diagnosed and monitored with conventional markers that have poor sensitivity and specificity. As genomics, transcriptomics, proteomics, and metabolomics continue to develop, a new era of precision nephrology is emerging. It will enable us to diagnose earlier, predict more precisely, and tailor our treatment.

This Special Issue welcomes original research, reviews, and translational analyses of molecular mechanisms of kidney disease, new diagnostic and prognostic biomarkers, and new technologies such as single-cell sequencing, liquid biopsy, and spatial transcriptomics. 

We aim to encourage development that closes the gap between translational research and clinical application, e.g., research on genetic mutations, epigenetic regulation, and fluid biomarkers such as cell-free DNA, microRNAs, and exosomes. Manuscripts reporting biomarker validation and clinical translation are especially encouraged.

Prof. Dr. Marijn Speeckaert
Guest Editor

Manuscript Submission Information

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