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Collagen and Its Derivatives in Tissue Engineering

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".

Deadline for manuscript submissions: 30 September 2025 | Viewed by 31

Special Issue Editor


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Guest Editor
Institute of Translational Medicine, Semmelweis University, 1094 Budapest, Hungary
Interests: biomolecular materials; tissue engineering; material science; in vitro and in vivo biodegradation; medical device development
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue will be dedicated to exploring the diverse scientific and practical applications of collagen derivatives, a promising class of biomolecular materials. As a popular naturally occurring material, it has numerous derivatives. Among them, biodegradable, and often biocompatible, substances and collagen-based materials are extremely interesting from a material science viewpoint. These derivatives also play a crucial role in both in vitro and in vivo biomedical applications. Their versatility allows for their integration into various regenerative strategies, including tissue engineering, drug delivery systems, wound healing matrices, and implantable scaffolds.

This Special Issue will focus on collagen derivatives alone or in composite form, as well as comparisons with other natural or synthetic polymers such as starch, hyaluronic acid, poly-vinyl alcohol (PVA), poly-ethylene glycol (PEG), and poly-lactic acid (PLA). An emphasis will be placed on applications involving functional tissue restoration—in bone, cartilage, muscle, tendons, or skin—or artificial constructs, utilizing collagen-derived materials in grafts, implants, or drug carriers.

Topics of interest include, but are not limited to, the following:

  • In vitro experiments involving collagen derivatives, such as sustained or controlled release, toxicity assessments, and cellular interactions;
  • In vivo investigations using animal models to evaluate regenerative efficacy, inflammation modulation, or biodegradation;
  • Theoretical modeling of material degradation, nanoscale structure–function relationships, or the integration of collagen into 3D-printed systems;
  • Industrial perspectives on collagen derivatives, including manufacturing, regulatory aspects, quality control, and clinical translation.

Submissions of original research articles, reviews, mini-reviews, and methodological studies centered on collagen derivatives are encouraged.

Dr. István Hornyák
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • collagen derivatives
  • tissue engineering
  • in vitro experiments
  • in vivo investigations
  • material degradation

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Published Papers

This special issue is now open for submission.
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