Submit to Cells Review for Cells Propose a Special Issue

Journal Menu

Journal Browser

Special Issues

Cells publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

Section

Search by Title/Keyword

Order results

Display

Results per page

Pathology and Treatments of Amyotrophic Lateral Sclerosis (ALS)

edited by Laxman Gangwani

submission deadline 28 Nov 2025 | 1 articles | Viewed by 2093 | Submission Open

Keywords: amyotrophic lateral sclerosis (ALS); pathology; molecular mechanisms; treatments; symptom management; biological mechanisms; risk factors; innovative treatments

(This special issue belongs to the Section Cellular Pathology)

Cellular Senescence and Senotherapies in the Aging Retina

edited by

Bhavana Chhunchha

submission deadline 28 Nov 2025 | Viewed by 320 | Submission Open

Keywords: retina; senescence; aging; inflammasome; oxidative stress; antioxidant; gene therapy; senotherapies; glaucoma; diabetic retinopathy

(This special issue belongs to the Section Cellular Aging)

Cell-to-Cell Crosstalk as a Target of Therapies

edited by

Agnieszka Gizak

and

Dominika Drulis-Fajdasz

submission deadline 30 Nov 2025 | 2 articles | Viewed by 10814 | Submission Open

Keywords: cell-to-cell crosstalk; cellular communication; microenvironment; extracellular vesicles; diagnostic tools; membrane nanotubes; pathogenesis; therapy; cell metabolism; homeostasis

(This special issue belongs to the Section Cell Microenvironment)

Gastrointestinal Cancer: From Cellular and Molecular Mechanisms to Therapeutic Opportunities

edited by

Federica Laudisi

and

Carmine Stolfi

submission deadline 30 Nov 2025 | 4 articles | Viewed by 7734 | Submission Open

Keywords: colorectal cancer; gastric cancer; liver cancer; pancreatic cancer; tumor microenvironment; cytokines; epigenetic; checkpoint inhibitors; biomarkers; immunotherapy

(This special issue belongs to the Section Cellular Pathology)

Emerging Insights into Natural Killer Cell Immunity in Infection and Cancer

edited by Sumit Sen Santara,

Engin Berber

, Weshely Kujur and Sachin Mulik

submission deadline 30 Nov 2025 | 4 articles | Viewed by 7649 | Submission Open

Keywords: CAR NK cells; cancer immunotherapy; cell therapy; viral infection; memory NK cells; NK cell targeted therapies; NK-immune cell crosstalk; exosomes

(This special issue belongs to the Section Cellular Immunology)

New Research on Immunity and Inflammation in Cardiovascular Disease

edited by Pavel Poredoš

submission deadline 30 Nov 2025 | 7 articles | Viewed by 7242 | Submission Open

Keywords: inflammation; atherosclerosis; coronary artery disease; peripheral arterial disease; cerebrovascular disease; venous thromboembolic disease; circulating biomarkers; anti-innflammatory treatment of cardiovascular disease

(This special issue belongs to the Section Cells of the Cardiovascular System)

Recent Advances in Metabolism and Oxidative Stress in Human Diseases: 2nd Edition

edited by

Isabella Panfoli

and Vanessa Cossu

submission deadline 30 Nov 2025 | 4 articles | Viewed by 6924 | Submission Open

Keywords: antioxidant responses; redox balance; ROS; hematologic oncology; solid tumors; immune response; ATP; cancer cells; mitochondria-ER interactions; endoplasmic reticulum; glucose metabolism; inflammation; mitochondria; mitochondrial dynamics; autophagy; mitophagy; metabolic plasticity; metabolism

(This special issue belongs to the Section Cellular Metabolism)

Advances in Muscle Research in Health and Disease—2nd Edition

edited by

Wan Lee

submission deadline 30 Nov 2025 | 3 articles | Viewed by 5658 | Submission Open

Keywords: skeletal muscle; cardiac muscle; smooth muscle; myocyte; vascular smooth muscle cell; stem cell; development; homeostasis; regeneration; biomarker; therapeutic target

(This special issue belongs to the Section Tissues and Organs)

Harnessing the Tumor Microenvironment and Signaling Pathways for Precision Cancer Therapy

edited by Behzad M. Toosi and

Andrew Freywald

submission deadline 30 Nov 2025 | 2 articles | Viewed by 4710 | Submission Open

Keywords: tumor microenvironment (TME); signaling pathways; precision cancer therapy; immune evasion; metabolic pathways; tumor– stroma interactions; therapeutic targets; personalized medicine; cancer metastasis; molecular oncology

(This special issue belongs to the Section Cell Microenvironment)

Role of Calpains in Health and Diseases

edited by

Michel Baudry

and Peter A. Greer

submission deadline 30 Nov 2025 | 4 articles | Viewed by 4480 | Submission Open

Keywords: calpain; physiology; biochemistry; disease; mutation; target; inhibitor

(This special issue belongs to the Section Cellular Pathology)

Retinal Pigment Epithelium in Degenerative Retinal Diseases

edited by Jian Liu and Shintaro Horie

submission deadline 30 Nov 2025 | 3 articles | Viewed by 4477 | Submission Open

Keywords: RPE; degenerative retinal diseases; macular degeneration; diabetic retinopathy; glaucoma; photoreceptor; vascular endothelium; microglia; macrophage; inflammation; oxidative stress; autophagy; mitochondria; lipid metabolism; senescence; neuropeptide; therapeutics; biomarkers

(This special issue belongs to the Section Cellular Pathology)

Cellular Mechanisms in Mitochondrial Function and Calcium Signaling

edited by Sergio De la Fuente and Jaime Santo-Domingo

submission deadline 30 Nov 2025 | 2 articles | Viewed by 3603 | Submission Open

Keywords: mitochondria; calcium; MCU; uniporter; NCLX; energy metabolism; disease; MAMs; signaling

(This special issue belongs to the Section Cellular Metabolism)

Genetic and Cellular Basis of Autoimmune Diseases

edited by

Christian Sadik

submission deadline 30 Nov 2025 | 2 articles | Viewed by 3496 | Submission Open

Keywords: autoimmune disease; break of tolerance; effector cells; immunodysregulation; risk genes

(This special issue belongs to the Section Cellular Immunology)

Osteoblasts, Osteoclasts and Bone Diseases: Cellular Crosstalk and Therapeutic Opportunities

edited by

Thomas Nicholson

submission deadline 30 Nov 2025 | 1 articles | Viewed by 3407 | Submission Open

Keywords: osteoblasts; osteoclasts; bone remodelling; osteoporosis; skeletal diseases; bone homeostasis; bone interactions; bone crosstalk; targeted therapies

(This special issue belongs to the Section Cellular Pathology)

Advances in Musculoskeletal Tissue Regeneration Using Mesenchymal Stromal/Stem Cells, Biomaterials, and Signaling Molecules: Second Edition

edited by

Dimitrios Kouroupis

and

Thomas M. Best

submission deadline 30 Nov 2025 | 2 articles | Viewed by 3369 | Submission Open

Keywords: mesenchymal stromal/stem cells; extracellular vesicles; biomaterials; signalling molecules; microphysiological systems; musculoskeletal regeneration; immunomodulation; cell therapy; tissue engineering

(This special issue belongs to the Section Stem Cells)

CRISPR-Based Genome Editing Approaches in Cancer Therapy

edited by Martin Pal

submission deadline 30 Nov 2025 | 2 articles | Viewed by 2559 | Submission Open

Keywords: CRISPR; genome editing; cancer therapy; precision medicine

(This special issue belongs to the Section Cell and Gene Therapy)

Neuroinflammation in Developmental Brain Diseases

edited by

Evelyne Gozal

Jun Cai

and

Gregory Neal Barnes

submission deadline 30 Nov 2025 | 1 articles | Viewed by 2420 | Submission Open

Keywords: neuroinflammation; endothelial injury; blood brain barrier; microglia; immune dysfunction; oxidative stress; autism spectrum disorders; epilepsy; cerebral palsy; schizophrenia; neurodevelopment; neurovascular brain signaling; inflammatory cytokines; immune cells

(This special issue belongs to the Section Cells of the Nervous System)

Emerging Advances in Neurodegeneration: Innovations in Stem Cell and Organoid Research

edited by

Elena Coccia

submission deadline 30 Nov 2025 | 1 articles | Viewed by 2093 | Submission Open

Keywords: neurodegeneration; stem cells; induced pluripotent stem cells (iPSCs); brain organoids; disease modeling; therapeutic strategies; personalized medicine

(This special issue belongs to the Section Stem Cells)

Aging and Neurodegeneration: Molecular Insights and Emerging Strategies

edited by

Piotr Paweł Chmielewski

submission deadline 30 Nov 2025 | 1 articles | Viewed by 2092 | Submission Open

Keywords: Alzheimer’ s disease; biomarkers; endolysosomal pathway; extracellular vesicles; inflammation; mitophagy; neurodegeneration; neuroinflammation; Parkinson’ s disease; translational research

(This special issue belongs to the Section Cellular Aging)

Epigenetic Regulatory Networks in Cancer: Understanding the Mechanisms of Disease Progression

edited by

Anand Singh

and Sudheer Kumar Gara

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1739 | Submission Open

Keywords: cancer; epigenetics; miRNAs; BAP1; DNMTs; tumor suppressor; oncogenes; histone modification; chromatin remodeling

(This special issue belongs to the Section Cellular Pathology)

Modulation of Senescence and Differentiation in Human Mesenchymal Stem Cells

edited by

Federica Facchin

and

Silvia Canaider

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1734 | Submission Open

Keywords: tissue-specific mesenchymal stem cells; cell senescence; cell differentiation; natural and synthetic molecules; tissue engineering; regenerative medicine

(This special issue belongs to the Section Stem Cells)

Myocardial Ischemia/Reperfusion Injury: Mechanisms and New Directions in Cardioprotection

edited by Sauri Hernandez-Resendiz

submission deadline 30 Nov 2025 | 2 articles | Viewed by 1390 | Submission Open

Keywords: myocardial infarction; heart failure; ischemia/reperfusion injury; no-reflow phenomenon; oxidative stress; cell death; cardiac metabolism; mitochondrial quality control; inflammation; cardioprotection

(This special issue belongs to the Section Tissues and Organs)

Updates of Stem Cell Applications in Bone Tissue Engineering

edited by Fahad Karim Kidwai

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1380 | Submission Open

Keywords: stem cells; bone tissue engineering; bone diseases; bone repair; bone defect; bone healing; bone regeneration; osteogenic progenitor cells

(This special issue belongs to the Section Stem Cells)

Molecular and Cellular Mechanisms of Brain Development and Neurodevelopmental Disorders

edited by

Mojgan Rastegar

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1325 | Submission Open

Keywords: brain development; neural stem cells; neurodevelopmental disorders; brain diseases; cellular and molecular mechanisms; embryonic and adult brain

(This special issue belongs to the Section Cellular Pathology)

Non-Coding RNAs as Regulators of Cellular Function and Disease

edited by

Lucia Natarelli

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1214 | Submission Open

Keywords: non-coding RNAs; gene regulation; disease mechanisms; therapeutic targets; molecular mechanisms

Cellular and Molecular Mechanisms of Wound Repair

edited by

Elia Ranzato

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1016 | Submission Open

Keywords: wound healing; cellular mechanisms; tissue remodeling; growth factors; extracellular matrix; tissue regeneration

(This special issue belongs to the Section Cellular Pathology)

Adipose-Derived Stem Cells for Tissue Regeneration

edited by

Lukas Prantl, MD, PhD, MHBA, FACS

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1006 | Submission Open

Keywords: adipose stem cells (ASCs); stromal vascular fraction (SVF); cell enriched lipotransfer (CELT and CELT-PLUS); extracellular vesicles (EVs); tissue processing; basic biology; mechanisms of action; regenerative medicine; cell-bases therapies

(This special issue belongs to the Section Tissues and Organs)

Brain Organoids for Disease Modeling

edited by

Jonghun Kim

submission deadline 30 Nov 2025 | 1 articles | Viewed by 873 | Submission Open

Keywords: brain organoids; induced pluripotent stem cells (iPSCs); neurodevelopmental disorders; neurodegenerative diseases; neuronal activity; organoid-based drug screening

(This special issue belongs to the Section Stem Cells)

G Protein-Coupled Receptors and Diseases

edited by

Yongqiang Chen

submission deadline 30 Nov 2025 | Viewed by 555 | Submission Open

Keywords: G protein-coupled receptor; taste receptor; microbiome; cancer; aging; neurodegenerative disease; cardiovascular disease; pulmonary hypertension; cell survival; cell death; apoptosis; autophagy; necroptosis; ferroptosis; proliferation

Drug Resistance in Breast and Ovarian Cancers

edited by

Tuula Kallunki

submission deadline 30 Nov 2025 | Viewed by 385 | Submission Open

Keywords: breast cancer; endocrine resistance; ESR1 mutations; Trop-2; ovarian cancer; drug resistance; predictive biomarkers; personalized medicine

Hypoxia Pathway Proteins in the Immune System: Regulation, Disease, and Therapeutics

edited by Ben Wielockx

submission deadline 30 Nov 2025 | Viewed by 348 | Submission Open

Keywords: hypoxia; oxygen sensors; immune system; HIF; disease mechanisms; therapeutics; inflammation; autoimmunity; cancer immunology

(This special issue belongs to the Section Cellular Immunology)

Exploring Morphological Changes and Diversity in Cancer

edited by

Mustapha Kandouz

submission deadline 30 Nov 2025 | Viewed by 282 | Submission Open

Keywords: morphology; heterogeneity; cancer; phenotype; shape

Exploring the Structural and Functional Diversity of Proteins: Foundations of Life and Biological Complexity

edited by Jiabei Lin

submission deadline 30 Nov 2025 | Viewed by 253 | Submission Open

Keywords: AAA+ protein; RNA-binding protein; protein kinase; PTMs; protein structure; function; and diseases; protein and RNA homeostasis; neurodegeneration; cancer

Molecular Research in Osteoporosis

edited by

Virginia Visconti

Annalisa Botta

and

Umberto Tarantino

submission deadline 30 Nov 2025 | Viewed by 182 | Submission Open

Keywords: osteoporosis; osteosarcopenia; bone– muscle crosstalk; genetics; epigenetics; transcriptomics; biomarkers; therapeutic strategy

(This special issue belongs to the Section Cellular Pathology)

Redox Regulation by Nrf2 in Health and Disease

edited by Pandu Gangula

submission deadline 30 Nov 2025 | Viewed by 160 | Submission Open

Keywords: Nrf2; redox; cellular stress response; antioxidant gene regulation; signaling pathway crosstalk; oxidative stress response

Crossroad Between Oxidative Stress and DNA Damage and Repair in Stroke

edited by

William James Antonisamy

Zahoor Shah

and Moorthi Ponnusamy

submission deadline 30 Nov 2025 | Viewed by 160 | Submission Open

Keywords: oxidative stress; DNA damage; DNA repair; stroke; ischemic stroke; neuroinflamamtion; intracranial hemorrhagic stroke; neuronal death

(This special issue belongs to the Section Cells of the Nervous System)

ROS in Atherosclerosis and Cardiometabolic Disorders

edited by

Weibin Shi

submission deadline 30 Nov 2025 | Viewed by 154 | Submission Open

Keywords: reactive oxygen/nitrogen species; oxidative stress; atherosclerosis; cardiovascular; inflammation; endothelial dysfunction; obesity; dyslipidemia

(This special issue belongs to the Section Tissues and Organs)

Lung Cancer: Molecular Mechanisms and Therapeutic Opportunities

edited by

Sherri R. Cervantes

and

Daruka Mahadevan

submission deadline 30 Nov 2025 | Viewed by 129 | Submission Open

Keywords: precision oncology; immunotherapy; targeted therapy; genomic characterization; biomarker; microenvironment; non-small cell lung cancer; small cell lung cancer

(This special issue belongs to the Section Cell Microenvironment)

Molecular Mechanisms of Drug Delivery in Ophthalmology

edited by Alekha K. Dash and Surabhi Shukla

submission deadline 30 Nov 2025 | Viewed by 129 | Submission Open

Keywords: drug delivery; ophthalmology; nanocarriers; ocular barriers; molecular transport; targeted therapy; ocular gene delivery

(This special issue belongs to the Section Tissues and Organs)

Protein and RNA Regulation in Cells

edited by

Delai Huang

and

Denis Mottet

submission deadline 30 Nov 2025 | Viewed by 123 | Submission Open

Keywords: gene expression; post-transcriptional regulation; post-translational modifications; non-coding RNAs; regulatory networks; protein degradation; RNA decay

The Cellular and Molecular Basis of Lifestyle Factors in Cancer Progression and Prevention

edited by Vivek Kumar Kashyap and Himanshu Narayan Singh

submission deadline 30 Nov 2025 | Viewed by 122 | Submission Open

Keywords: lifestyle factors; smoking; alcohol consumption; cancer risk; cancer prevention recommendations; modifiable risk factors

(This special issue belongs to the Section Cellular Pathology)

Extracellular Vesicles in Neurodegenerative Diseases: From Biomarker Discovery to Precision Therapeutics

edited by Mangesh Dattu Hade

submission deadline 30 Nov 2025 | Viewed by 102 | Submission Open

Keywords: neurodegenerative diseases; extracellular vesicles; Alzheimer's disease; Parkinson's disease; multiple sclerosis; blood– brain barrier; neuroinflammation; biomarker discovery; EV-based therapeutics; precision medicine

(This special issue belongs to the Section Cellular Aging)

Cellular and Molecular Mechanisms of Hepatobiliary Diseases

edited by

Stefan Hoehme

and

Jan G. Hengstler

submission deadline 30 Nov 2025 | Viewed by 100 | Submission Open

Keywords: hepatobiliary diseases; bile metabolism; hepatobiliary models; artificial intelligence; cholestatic diseases; systems medicine; spatio-temporal liver models

(This special issue belongs to the Section Tissues and Organs)

Emerging Cell Therapies and Regenerative Approaches in Pulmonary Medicine

edited by Renata Kelly Da Palma

submission deadline 30 Nov 2025 | Viewed by 97 | Submission Open

Keywords: cell therapy; lung diseases; tissue regeneration

(This special issue belongs to the Section Tissues and Organs)

Brain Insulin Resistance in Neurodegenerative Disorders and Its Treatments

edited by Konrad Talbot

submission deadline 30 Nov 2025 | Viewed by 93 | Submission Open

Keywords: Alzheimer’ s disease; brain insulin resistance; Down syndrome; incretin receptor agonist; insulin; insulin resistance; multiple system atrophy; neurodegenerative disease; Parkinson’ s disease

(This special issue belongs to the Section Cells of the Nervous System)

New Advances in Cardiac and Vascular Physiology

edited by Robert M. Lust

submission deadline 30 Nov 2025 | Viewed by 82 | Submission Open

Keywords: environmental exposure; immune responses; remodeling; receptors; ischemia; pre-conditioning; post-conditioning; heart failure

(This special issue belongs to the Section Tissues and Organs)

Advances in Pulmonary Fibrosis

edited by Sergio Piñeiro Hermida

submission deadline 1 Dec 2025 | 1 articles | Viewed by 596 | Submission Open

Keywords: pulmonary fibrosis; animal models; biomarkers; experimental therapeutics

(This special issue belongs to the Section Cellular Pathology)

The Spatial and Temporal Dynamics of the Tumor Microenvironment

edited by

Shilpa Bisht

, Abhishek Gupta, Anjali Trivedi and

Alessandra Ferraresi

submission deadline 1 Dec 2025 | Viewed by 462 | Submission Open

Keywords: tumor microenvironment; spatial heterogeneity; spatial transcriptomics; tumor evolution; immune landscape; extracellular matrix; tumor– immune crosstalk; cancer heterogeneity; intra-tumoral heterogeneity; tumor niches

(This special issue belongs to the Section Cell Microenvironment)

The Role of Macrophages and Neutrophils in Chronic Inflammation-Related Disorders

edited by

Pei-Hui Lin

and

Kumaraswami Konda

submission deadline 5 Dec 2025 | 6 articles | Viewed by 16231 | Submission Open

Keywords: chronic inflammation; neutrophils; macrophages; Alzheimer’ s disease; aging; cardiovascular diseases; obesity; cancer; fibrosis; tissue injury and repair

(This special issue belongs to the Section Cellular Immunology)

New Targets and Therapeutic Approaches Based on Molecular Mechanisms in Tumorigenesis and Cancer Metastasis

edited by

Francesc Mitjans

submission deadline 10 Dec 2025 | 2 articles | Viewed by 4131 | Submission Open

Keywords: metastasis; cancer; therapy; precision medicine; cancer stem cells; immuno-oncology; tumor microenvironment; antibody

(This special issue belongs to the Section Cell Microenvironment)

Displaying special issue 101-150 on page 3 of 13.

Go to page 1 2 3 4 5

Journal Menu

Journal Browser

Special Issues

Further Information

Guidelines

MDPI Initiatives

Follow MDPI