Molecular Mechanisms of Trophoblast Differentiation
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 25 March 2026 | Viewed by 82
Special Issue Editors
Interests: immunohistochemistry; cell culture; western blot analysis; gel electrophoresis; RNA isolation; RNA extraction; immunofluorescence; SDS-page; cell line culture; agarose gel electrophoresis
Interests: cancer biology; cancer genetics; endometriosis; pathology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The placenta is a unique transient organ that forms during early pregnancy and plays a vital role in supporting fetal development and growth. Abnormal placentation can lead to various pregnancy complications—including miscarriage, preeclampsia, and intrauterine growth restriction—and may have lasting effects on the health of the offspring.
The successful development of the placenta depends on a finely regulated sequence of trophoblast cell differentiation. Recent advances have uncovered a complex network of molecular pathways, transcriptional programs, and epigenetic modifications that guide the formation and specialization of trophoblast lineages.
This Special Issue, entitled “Molecular Mechanisms of Trophoblast Differentiation”, aims to present new insights into the regulatory processes that govern trophoblast fate decisions, invasion, and interactions with maternal tissues. By integrating findings from model systems, human studies, and emerging technologies, the contributions in this issue will enhance our understanding of placental development and its relevance to maternal and fetal health, shedding light on both normal physiology and pregnancy-related disorders.
We warmly invite you to submit your latest original research articles or reviews to this Special Issue.
Dr. Milica Jovanović Krivokuća
Prof. Dr. Jianjun Wei
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- trophoblast differentiation
- cytotrophoblast
- syncytiotrophoblast
- extravillous trophoblast
- trophoblast stem cells
- molecular mechanisms
- signaling pathways
- epigenetic regulation
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
