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Cellular Responses During Wound and Regeneration

A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Stem Cells".

Deadline for manuscript submissions: 30 August 2026 | Viewed by 2

Special Issue Editors


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Guest Editor
Department of Molecular and Cellular Biology, Kennesaw State University, Kennesaw, GA 30144, USA
Interests: inflammation; wound and regeneration; reactive oxygen species; metallothioneins

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Guest Editor
Department of Biological Sciences, 218 Galvin Life Sciences Center, University of Notre Dame, Notre Dame, IN 46556, USA
Interests: development; pattern formation; organogenesis; regeneration; stem cell biology; nephrogenesis; hematopoiesis
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Special Issue Information

Dear Colleagues,

Wound formation begins with tissue damage, often disrupting the epithelial barrier and deep tissues. This action causes blood vessel injury and triggers platelet-mediated clot formation to prevent further bleeding. This damage also initiates an inflammatory response, where neutrophils and macrophages rush to the site to clear pathogens and debris. Following this, wound regeneration begins with the proliferation phase, during which fibroblasts produce collagen and rebuild the extracellular matrix. Additionally, keratinocytes migrate to restore the skin surface, and angiogenesis generates new blood vessels to support tissue repair. Later stages of the healing process employ myofibroblasts to contract the wound and aid in tissue remodeling.

This Special Issue will highlight current knowledge in the field of wound healing and regeneration. Articles may include experimental research that elucidates cell signaling events under normal and diseased conditions (e.g., diabetes). Reviews and original research articles are welcome.

Dr. Eric A. Albrecht
Dr. Rebecca A. Wingert
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • inflammation
  • wound and regeneration
  • clotting
  • reduction–oxidation reactions
  • fibroblasts
  • proliferation
  • endothelial
  • extracellular matrix

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Published Papers

This special issue is now open for submission.
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