Gut Microbiota, Metabolites, and Immune Regulation in Gastrointestinal Diseases
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 31 August 2026 | Viewed by 20
Special Issue Editor
Interests: immunology; cancer biology; inflammation; stem cell biology; infection immunology
Special Issue Information
Dear Colleagues,
In recent years, gut microbiota and microbial metabolites have emerged as regulators of gastro-intestinal (GI) diseases. The gut microbiota and its metabolites play a critical role in immune regulation, influencing both local and systemic immune responses in the GI tract and beyond. In GI diseases, an imbalanced microbiome (dysbiosis) disrupts this delicate equilibrium, contributing to chronic inflammation and disease progression. Inflammatory Bowel Disease (IBD), Irritable Bowel Syndrome (IBS), and colorectal cancer (CRC) are among the several GI disorders that arise because of immune homeostasis being altered by microbial dysbiosis and changed metabolites. Gut barrier dysfunction, chronic inflammation and susceptibility to other diseases are major concerns for GI diseases. Therapeutic strategies targeting or manipulating the gut microbiota and its metabolites represent a promising avenue for novel GI disease therapies. This Special Issue welcomes manuscripts focusing on any aspect of gut microbiota, metabolite and immunoregulations related to GI diseases.
Dr. Sweta Ghosh
Guest Editor
Manuscript Submission Information
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Keywords
- gut microbiota
- microbial metabolites
- inflammation
- immunology
- gut-barrier
- gastrointestinal disease
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