Ocular Surface and Adnexal Diseases: Molecular Mechanisms and Treatment Progresses

A special issue of Cells (ISSN 2073-4409).

Deadline for manuscript submissions: 28 February 2026 | Viewed by 44

Special Issue Editor


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Guest Editor
Department of Ophtalmology, Albert Szent-Györgyi Health Centre, University of Szeged, Korányi Fasor 10-11, H-6720 Szeged, Hungary
Interests: dry eye disease; tear biomarkers; eyelid diseases; lacrimal gland diseases; molecular mechanisms

Special Issue Information

Dear Colleagues,

We are pleased to announce a forthcoming Cells Special Issue titled “Ocular Surface and Adnexal Diseases: Molecular Mechanisms and Treatment Progresses”. This issue will serve as a comprehensive platform for research dedicated to exploring the cellular and molecular mechanisms underlying ocular surface, eyelid, and lacrimal gland diseases, alongside highlighting cutting-edge developments in clinical strategies for their treatment.

Ocular surface and adnexal diseases—including dry eye disease, blepharitis, meibomian gland dysfunction, conjunctivitis, lacrimal gland diseases, and corneal disorders—affect millions worldwide and significantly impair visual function and quality of life. Recent years have witnessed considerable progress in our understanding of the pathogenesis of these conditions, encompassing inflammatory signaling pathways, epithelial barrier dysfunction, immune cell dynamics, microbiome alterations, and neurogenic mechanisms. Simultaneously, novel therapeutic strategies, ranging from biologics to regenerative approaches, are being developed and evaluated.

This Special Issue invites contributions that explore, but are not limited to, the following topics:

  • Cellular and molecular mechanisms underlying ocular surface inflammation and degeneration;
  • Role of immune cells and cytokines in disease progression;
  • Epithelial–mesenchymal interactions and wound healing;
  • Pathomechanisms of eyelid diseases;
  • New treatment options for eyelid diseases;
  • Advances in diagnostics and molecular biomarkers;
  • Impact of microbiota on ocular surface health and disease;
  • Preclinical and clinical studies of emerging therapeutic approaches;
  • Gene- and cell-based therapies for ocular surface regeneration;
  • Drug delivery systems targeting the ocular surface.

Both original research articles and high-quality reviews are welcome. Contributions should provide new insights or critical syntheses that advance the understanding of ocular surface/adnexal diseases and/or improve patient outcomes through innovative treatments.

Prof. Dr. Edit Tóth-Molnár
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • ocular surface and adnexal diseases
  • dry eye disease
  • eyelid diseases
  • lacrimal gland diseases
  • molecular mechanisms
  • therapeutic strategies

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Published Papers

This special issue is now open for submission.
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