The Lipid Metabolism and Signaling in Dry Eye Disease
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 28 February 2026 | Viewed by 47
Special Issue Editors
Interests: lipid metabolism and signaling; lipid-processing enzymes; meibogenesis; molecular mechanisms and etiology of diseases (especially dry eye disease); therapeutic discovery; lipid-derived natural products; retinoid and carotenoid homeostasis
Interests: lipid metabolism; lipid processing enzymes; lipid-binding proteins; lipid signaling; meibogenesis; molecular mechanism of diseases; drug discovery; pharmacology of ocular diseases
Special Issue Information
Dear Colleagues,
Lipid metabolism and signaling play a pivotal role in maintaining ocular surface health. Dysregulation of lipid homeostasis is implicated in the pathogenesis of various forms of dry eye disease (DED), including Meibomian gland dysfunction, neuroinflammation, and injury-induced pathology. This Special Issue aims to advance understanding of lipid biology in DED by encompassing studies on molecular mechanisms, disease pathophysiology. We welcome original research and reviews on therapeutic strategies, as well as the application of emerging technologies, such as spatial transcriptomics, lipidomics, and advanced imaging that enhance lipid-focused ocular research. Submissions exploring lipid–neural interactions and system-level approaches are particularly encouraged to foster novel insights and translational innovations for the diagnosis and management of this prevalent ocular condition.
Dr. Ni Made Airanthi Kusuma Widjaja-Adhi
Dr. Marcin Golczak
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- lipid metabolism
- meibogenesis
- dry eye disease (DED)
- meibomian gland dysfunction (MGD)
- ocular surface
- neuroinflammation
- tear film
- lipidomics
- spatial transcriptomics
- therapeutics development
- molecular mechanisms
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