Role of Oxidative Stress in Cardiovascular Diseases
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cells of the Cardiovascular System".
Deadline for manuscript submissions: 31 January 2026
Special Issue Editors
Interests: oxidative stress; cardiovascular pharmacology; diabetes; apoptosis; pharmaceutical chemistry; hypertension; antioxidants; reactive oxygen species
Special Issues, Collections and Topics in MDPI journals
Interests: oxidative stress; cardiology; pharmacology; diabetes; apoptosis; internal medicine; hypertension; antioxidants; reactive oxygen species; rehabilitation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear colleagues,
Cardiovascular diseases remain the leading cause of mortality worldwide, with oxidative stress recognized as a major contributor to disease onset and progression. An imbalance between reactive oxygen species (ROS) and the body's antioxidant defense mechanisms leads to endothelial dysfunction, inflammation, lipid oxidation, and cellular damage—key drivers of atherosclerosis, hypertension, myocardial infarction, and heart failure.
Oxidative stress influences multiple aspects of vascular biology, including vascular smooth muscle cell modulation, immune responses, and metabolic dysfunction. Various environmental and pathological stimuli exacerbate oxidative damage, further accelerating vascular disease. While current treatments focus on managing traditional cardiovascular risk factors, they often fail to comprehensively address the underlying oxidative processes contributing to disease pathology.
This Special Issue aims to highlight the latest advances in understanding the role of oxidative stress in cardiovascular disease at the molecular, cellular, and clinical levels. We welcome original research and review articles that explore mechanistic insights, potential therapeutic targets, and novel strategies to mitigate oxidative damage and improve cardiovascular health.
Dr. Jeremic Nevena
Dr. Vladimir Jakovljevic
Guest Editors
Dr. Nevena Jeremic
Prof. Dr. Vladimir Jakovljevic
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- oxidative stress
- reactive oxygen species (ROS)
- endothelial dysfunction
- inflammation
- cardiovascular pathology
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