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Cancers
Special Issues
Perioperative Care in Gynecologic Oncology: 2nd Edition
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Perioperative Care in Gynecologic Oncology: 2nd Edition

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Survivorship and Quality of Life".

Deadline for manuscript submissions: 28 February 2026 | Viewed by 210

Special Issue Editors

Dr. Nikolaos Thomakos

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Guest Editor
Department of Obstetrics and Gynecology Medical School, Alexandra Hospital, University of Athens, Athens, Greece
Interests: gynecologic oncology
Special Issues, Collections and Topics in MDPI journals
Dr. Vasilios Pergialiotis

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Guest Editor
Gynaecologic Oncology Unit, 1st Department of Obstetrics and Gynaecology, Alexandra Hospital, National and Kapodistrian University of Athens, 11528 Athens, Greece
Interests: gynecologic oncology; endometrial cancer; cervical cancer; ovarian cancer; vulvar cancer; cytoreductive surgery
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue will provide an in-depth overview of our current knowledge regarding the factors affecting the perioperative course in gynecologic oncology patients, who often represent a difficult group in terms of perioperative management. Several interventions have been proposed in recent years for the optimization of variables in gynecologic oncology patients in order to help reduce perioperative morbidity rates.

Potential topics of interest include, but are not limited to, enhanced recovery protocols, novel techniques for the surgical management of gynecologic oncology patients, and novel aspects of immunonutrition, as well as predictive factors that may help in predicting disease course in these patients. This Special Issue will cover the management of patients with ovarian, endometrial, cervical, vulvar, and breast cancer. We seek contributions in the form of original research articles and reviews and invite leading experts to share their knowledge on the pathophysiology of perioperative recovery and the management of these patients.

Dr. Nikolaos Thomakos
Dr. Vasilios Pergialiotis
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • enhanced recovery
  • ERAS
  • immunonutrition
  • prehabilitation
  • gynecologic oncology
  • minimally invasive surgery

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Published Papers (1 paper)

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17 pages, 1905 KiB  
Systematic Review
The Impact of Prophylactic Negative Wound Pressure Treatment (NWPT) on Surgical Site Occurrences After Gynecologic Cancer Surgery: A Meta-Analysis of Randomized Controlled and Observational Cohort Studies
by Maximos Frountzas, Ioannis Karavolias, Christina Nikolaou, Orsalia Toutouza, Vasilios Pergialiotis and Konstantinos G. Toutouzas
Cancers 2025, 17(10), 1717; https://doi.org/10.3390/cancers17101717 - 20 May 2025
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Abstract
Background: Surgical site infections (SSIs) remain a serious problem following abdominal surgery due to gynecologic malignancies leading to increased hospitalization, high costs, and delays in adjuvant treatments; thus, SSIs affect overall survival. The aim of the present meta-analysis was to investigate the [...] Read more.
Background: Surgical site infections (SSIs) remain a serious problem following abdominal surgery due to gynecologic malignancies leading to increased hospitalization, high costs, and delays in adjuvant treatments; thus, SSIs affect overall survival. The aim of the present meta-analysis was to investigate the impact of closed incision–negative pressure wound treatment (ci-NPWT) systems on postoperative surgical site occurrences (SSOs) after gynecologic oncology surgery. Methods: The present meta-analysis was designed using the PRISMA guidelines. A search in several databases was conducted from inception until March 2025. Results: Overall, five studies were included; these studies enrolled 1174 patients in total, where 412 were treated with ci-NPWT systems and 762 were treated with conventional gauze. Patients treated with ci-NPWT systems presented with lower SSI rates (OR 0.40, 95% CI 0.15–1.10, p = 0.08), lower fascial dehiscence rates (OR 0.72, 95% CI 0.21–2.42, p = 0.59), and lower seroma formation rates (OR 0.70, 95% CI 0.25–1.93, p = 0.49), although statistical significance was not reached in all comparisons. On the other hand, patients treated with ci-NPWT systems also presented with higher postoperative hematoma formation rates (OR 1.38, 95% CI 0.32–5.99, p = 0.66), although statistical significance was not reached. Preoperative patient characteristics, operative parameters, and cancer characteristics were similar among the two study groups. Conclusions: The prophylactic use of ci-NPWT systems showed promising results in reducing postoperative SSOs after gynecologic cancer surgery. Nevertheless, prospectively designed studies are needed in the future to reach robust evidence that would enable the wide implementation of such devices in routine clinical practice. Full article
(This article belongs to the Special Issue Perioperative Care in Gynecologic Oncology: 2nd Edition)
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