Breast Cancer and Stem Cells
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Molecular Cancer Biology".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 38
Special Issue Editor
Special Issue Information
Dear Colleagues,
Despite significant research efforts and advancements in treatment, breast cancer continues to be one of the most common malignancies and a leading cause of cancer-related mortality among women worldwide. The risk of disease recurrence and the emergence of metastatic lesions continue to present substantial challenges in clinical management. A key factor underlying these challenges is the existence of cancer stem cells, a subpopulation of tumor cells with the unique ability to self-renew, differentiate, and evade conventional therapies. Accumulating evidence has demonstrated that both intrinsic and extrinsic cues play a critical role in controlling cancer stem cell function, which influences disease progression, metastasis, and resistance to therapy. This Special Issue explores the latest research on breast cancer stem cells, highlighting the complex and reciprocal interactions with their surrounding microenvironment at both primary and metastatic sites. It further underscores recent advances in therapeutic approaches targeting breast cancer stem cells and their interactions with the microenvironment, as well as recent work in the development of in vitro systems to model these interactions. Such advancements offer promising new directions for more effective and individualized treatments in breast cancer.
Dr. Leandro Marcelo Martinez
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- breast cancer
- cancer stem cells
- tumor microenvironment
- metastasis
- therapeutic strategies
- in vitro models
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