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Biosensors publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Hybrid Conductive Polymer-Based Biosensors: Innovations in Advanced Platforms for Diagnostics and Monitoring

edited by

Abijeet S. Mehta

submission deadline 30 Apr 2026 | Viewed by 475 | Submission Open

Keywords: conductive polymers; organic electrochemical transistors (OECTs); CMOS-based image sensors; piezoelectric biosensors; surface plasmon resonance (SPR) sensors; hybrid biosensors; biomedical diagnostics

(This special issue belongs to the Section Biosensor Materials)

Single-Molecule Biosensors: Recent Advances and Future Challenges

edited by Yujing Song and

Pavel Banerjee

submission deadline 30 Apr 2026 | Viewed by 210 | Submission Open

Keywords: single-molecule biosensors; digital counting; multiomics profiling; fluorescence microscopy; microRNA detection; protein biomarkers; mutant DNA; precision diagnostics; nanobiotechnology; lab-on-a-chip devices; clinical translation; data analysis; point-of-care diagnostics; high-throughput screening; surface passivation; probe engineering

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Novel Optical Fiber Sensors for Biochemical and Biological Applications

edited by

Li-Peng Sun

Lili Liang

and Dandan Sun

submission deadline 30 Apr 2026 | Viewed by 162 | Submission Open

Keywords: optical fiber; fiber optic devices; optical fiber sensor; interferometer; fiber grating; evanescent field; surface plasmon resonance; surface-enhanced Raman scattering; fiber optic fluorescence sensor; biosensor; biochemical sensor; biomedical sensor; fiber-optic drug delivery; diagnostics; therapy

(This special issue belongs to the Section Biosensor Materials)

Intelligent Microfluidic Biosensing

edited by

Xiwei Huang

submission deadline 30 Apr 2026 | 1 articles | Viewed by 161 | Submission Open

Keywords: microfluidics; intelligent bio-sensing; lab-on-a-chip; devices and systems; artificial intelligence; machine learning; data analytics; Internet of Medical Things (IoMT); point-of-care testing

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Biosensors for Monitoring and Diagnostics, 2nd Edition

edited by

Radivoje Prodanović

and

Dalibor M. Stanković

submission deadline 30 Apr 2026 | Viewed by 141 | Submission Open

Keywords: electrochemical sensors; optical sensors; biomarkers; sensing technologies; recognition elements; engineering

(This special issue belongs to the Section Biosensors and Healthcare)

Phototheranostic Biosensing Platforms for Cancer Diagnosis and Therapy

edited by

Yuxun Ding

Xuemei Wang

and Xiaohui Liu

submission deadline 30 Apr 2026 | Viewed by 130 | Submission Open

Keywords: Biomedical and biosensing material; Precise Diagnosis; Real-Time Therapy; Phototheranostic nanomaterial

(This special issue belongs to the Section Biosensors and Healthcare)

Recent Progress in Photoelectrochemical (PEC) Biosensors and Bioassays

edited by Yanhu Wang

submission deadline 30 Apr 2026 | Viewed by 79 | Submission Open

Keywords: photoelectrochemical biosensor; photoelectrochemical sensing; surface sensitization; charge separation and transfer; heterojunction construction; nanostructure engineering; photoactive material; light harvesting; semiconductor; environmental pollution; food safety; biomarker detection

(This special issue belongs to the Section Optical and Photonic Biosensors)

Wearable Sensors and Biosensors for Physiological Signals Measurement

edited by

Lijun Sun

submission deadline 1 May 2026 | 1 articles | Viewed by 2053 | Submission Open

Keywords: wearable sensors; wearable biosensors; monitoring; physiological signals; living organisms

(This special issue belongs to the Section Wearable Biosensors)

Translational Micro- and Nanofluidic Technologies for Clinical Diagnostics: From Development to Real-World Applications

edited by Rui Hu

submission deadline 1 May 2026 | 1 articles | Viewed by 750 | Submission Open

Keywords: micro/nanofluidic; clinical diagnostics; point-of-care diagnostics; translational medicine; biomarker detection

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Sensors for Detection of Bacteria and Their Toxins

edited by Hui Jiang

submission deadline 1 May 2026 | 2 articles | Viewed by 742 | Submission Open

Keywords: biosensors; bacteria; bacterial toxins; point of care testing; high-throughput analysis; microfluidic chip; nanomaterials

(This special issue belongs to the Section Biosensors and Healthcare)

Sensors for the Detection of Neurodegenerative Diseases: Biomarkers, Imaging, and AI-Driven Approaches

edited by

Haiming Luo

and

Liding Zhang

submission deadline 1 May 2026 | Viewed by 157 | Submission Open

Keywords: Alzheimer’ s disease biomarkers; neurodegenerative diseases; fluid biomarkers; neuroimaging (MRI; PET; OCT); multi-omics analysis; artificial intelligence in diagnosis; machine learning for dementia; digital biomarkers and wearable technology; nanotechnology-based biosensing

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Principles, Technologies, and Applications of Plasmonic Biosensors

edited by Jasmine Devadhasan

submission deadline 1 May 2026 | Viewed by 145 | Submission Open

Keywords: plasmonic nanomaterials; biosensor development; nanoplasmonics; label-free detection; biosensor integration; nanomaterial functionalization; biosensing applications; sensor nanofabrication; surface plasmon resonance (SPR); localized surface plasmon resonance (LSPR)

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Organic Materials for Biosensing, Bioimaging and Phototheranostics

edited by Dingyuan Yan and

Miaomiao Kang

submission deadline 1 May 2026 | Viewed by 27 | Submission Open

Keywords: near-infrared; biosensing and bioimaging; disease phototheranostics; in vitro diagnosis; in vivo imaging

(This special issue belongs to the Section Biosensor Materials)

Electrochemical Biosensing at the Frontier: Materials, Mechanisms, and Applications

edited by Dan Wu, Beibei Wang and Qin Wei

submission deadline 15 May 2026 | 1 articles | Viewed by 629 | Submission Open

Keywords: photoelectrochemical; electrochemiluminescence; electrochemistry; sensors; food safety; environmental monitoring; tumor biomarker detection

(This special issue belongs to the Section Biosensor Materials)

Microfluidics for Biomedical Applications (3rd Edition)

edited by

Nan Xiang

submission deadline 31 May 2026 | 14 articles | Viewed by 33826 | Submission Open

Keywords: microfluidics; cell manipulation and detection; point-of-care testing; lab on a chip; biomedical applications

(This special issue belongs to the Section Biosensors and Healthcare)

Advanced Fluorescence Biosensors

edited by Simone Berneschi and

Cosimo Trono

submission deadline 31 May 2026 | 7 articles | Viewed by 14891 | Submission Open

Keywords: fluorescence; biosensors; label-based biosensors; förster resonance energy transfer (FRET); metal-enhanced fluorescence (MEF); total internal reflection fluorescence (TIRF); nanomaterials; upconversion; optical microcavities; optical fibers

(This special issue belongs to the Section Optical and Photonic Biosensors)

Sensors for Environmental Monitoring and Food Safety—2nd Edition

edited by

Kevin C. Honeychurch

Martina Piano

and David Ferrier

submission deadline 31 May 2026 | 4 articles | Viewed by 7957 | Submission Open

Keywords: food; beverages; water; air; nanotechnology; enzymes; antibodies; DNA; aptamers; molecularly imprinted polymers; sensors; biosensors

(This special issue belongs to the Section Environmental Biosensors and Biosensing)

Optical Sensors for Biological Detection

edited by

Miquel Avella-Oliver

and

Ángel Maquieira

submission deadline 31 May 2026 | 4 articles | Viewed by 6888 | Submission Open

Keywords: label-free; biosensor; plasmonics; photonics; nanostructure; transduction; point-of-care; lab-on-a-chip; wearable; SPR; SERS; waveguiding; interferometry; immunosensor; DNA biosensors

(This special issue belongs to the Section Optical and Photonic Biosensors)

Advances, Challenges and Opportunities in the Use of 2D Materials for Biosensing and Biomedical Applications

edited by

Cheng-Te Lin

, Chen Ye,

Kunyan Zhang

and

Jeewan Ranasinghe

submission deadline 31 May 2026 | 3 articles | Viewed by 5508 | Submission Open

Keywords: 2D materials; surface functionalization; point-of-care diagnosis; biocompatibility; molecular recognition; limit of detection; sensitivity; biomarkers

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Recent Advances in Molecularly Imprinted-Polymer-Based Biosensors

edited by

José Ribeiro

Carlos Pereira

and Manuel A. Azenha

submission deadline 31 May 2026 | 2 articles | Viewed by 4079 | Submission Open

Keywords: molecularly imprinted polymers (MIPs); imprinted materials; molecular recognition; biomimetic devices; electrochemical sensing; optical sensing; food quality and safety; environmental monitoring; disease biomarkers; biomedical applications; health monitoring

(This special issue belongs to the Section Biosensors and Healthcare)

AI-Based Biosensors and Biomedical Imaging

edited by Keyu Meng and

Egidio De Benedetto

submission deadline 31 May 2026 | 1 articles | Viewed by 902 | Submission Open

Keywords: microsensors and biosensing interfaces; microfluidics and portable detection; fluorescence-based diagnostics; artificial intelligence (AI) in biosensing; personalized medicine and environmental monitoring

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Recent Advances in Electrochemiluminescence for Biosensor Development

edited by Foad Salehnia

submission deadline 31 May 2026 | Viewed by 376 | Submission Open

Keywords: electrochemiluminescence; biosensor; nanomaterial; disease detection; biomedical devices

(This special issue belongs to the Section Optical and Photonic Biosensors)

Applications of Nanomaterials in Optical and Photonic Biosensors

edited by Zhengbo Zhu and Hongwei Lei

submission deadline 31 May 2026 | Viewed by 211 | Submission Open

Keywords: nanomaterials; optical biosensors; photonic biosensors; surface plasmon resonance (SPR); quantum dots; carbon-based nanomaterials; two-dimensional materials; biosensing technologies

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Nano-Carbons in Biosensors

edited by

An-Yi Chang

submission deadline 31 May 2026 | Viewed by 132 | Submission Open

Keywords: nano-carbons; biosensors; nanomaterials; wearable devices; electrochemical sensors; drug delivery; micromotors; artificial intelligence

(This special issue belongs to the Section Biosensor Materials)

Interdisciplinary Advances: Lab-on-a-Chip Biosensors Shaping Precision Diagnosis

edited by

Xinye Chen

and Ke Du

submission deadline 31 May 2026 | Viewed by 129 | Submission Open

Keywords: lab-on-a-chip; microfluidics; biosensors; diagnosis; artificial intelligence; bio-MEMS

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Electrochemical Biosensors for Healthcare and Environmental Monitoring: Fundamentals and Applications

edited by Shuang Han and Yuewu Zhao

submission deadline 31 May 2026 | Viewed by 118 | Submission Open

Keywords: electrochemical biosensors; bio-nano interfaces; electron-transfer kinetics; CRISPR-based diagnostics; amplification-free detection; antifouling interfaces; wearable electrochemical sensors; lab-on-a-chip platforms; real-time pathogen monitoring; continuous biomarker analysis

(This special issue belongs to the Section Biosensors and Healthcare)

Recent Advances and Challenges in Development of Whole Cell Biosensors

edited by

Nicoletta Guaragnella

Cataldo Guaragnella

Ehtisham Wahid

and Ohiemi Benjamin Ocheja

submission deadline 31 May 2026 | Viewed by 106 | Submission Open

Keywords: whole cell biosensors; electrochemical biosensors; microbial sensing; cell immobilization; stress-responsive elements; bioelectrochemistry; environmental diagnostics; synthetic biology; real-time monitoring; biosensor stability

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Microbial Biosensors: Emerging Technologies and Future Directions

edited by

Songlin Chua

submission deadline 31 May 2026 | Viewed by 100 | Submission Open

Keywords: microbial biosensors; synthetic biology; whole-cell biosensors; environmental monitoring; pathogen detection; bioelectronic interfaces; point-of-care diagnostics; bioreporter systems; microfluidics; smart diagnostics

(This special issue belongs to the Section Environmental Biosensors and Biosensing)

Recent Progress in Micro/Nano-Photonic Biosensors for Biomedical Diagnostics

edited by

Donato Conteduca

and Isabel Barth

submission deadline 31 May 2026 | Viewed by 97 | Submission Open

Keywords: micro/nanophotonic biosensors; metasurfaces; optical microcavities; nanoplasmonics; integrated photonics; single-particle detection; extracellular vesicles; point-of-care diagnostics; precision medicine; lab-on-a-chip

(This special issue belongs to the Section Biosensors and Healthcare)

Biosensors in Biomedical Research and Diagnostics

edited by

Jianping Xia

and Shanglin Li

submission deadline 31 May 2026 | Viewed by 72 | Submission Open

Keywords: microfluidic biosensors; lab-on-a-chip; point-of-care diagnostics; biomarker detection; extracellular vesicles (EVs); circulating nucleic acids (cfDNA; miRNA); fabrication methods; biomedical applications; disease diagnostics; personalized medicine

(This special issue belongs to the Section Biosensors and Healthcare)

Functional Materials for Biosensing Applications (2nd Edition)

edited by

Jin-Ha Choi

submission deadline 31 May 2026 | Viewed by 53 | Submission Open

Keywords: biosensor; early diagnosis; nanoparticle; nanomaterial; functional material; graphene; mxene; organic material; inorganic material

(This special issue belongs to the Section Biosensor Materials)

The Research and Application of Lateral Flow Biosensors

edited by Guodong Liu and

Wei Chen

submission deadline 1 Jun 2026 | Viewed by 206 | Submission Open

Keywords: lateral flow biosensors; point-of-care; microfluidics; CRISPR; EXPAR; RPA; LAMP; aptamers; peptides; nucleic acid signal amplification

(This special issue belongs to the Section Biosensors and Healthcare)

Label-Free Electrochemical Biosensing

edited by

Bruno Campos Janegitz

and

Laís Canniatti Brazaca

submission deadline 1 Jun 2026 | Viewed by 170 | Submission Open

Keywords: label-free detection; nanomaterials in biosensing; biomolecular interaction; medical diagnostics; environmental monitoring; point-of-care devices

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Nano-Biosensors and Their Applications for In Vivo/Vitro Diagnosis—3rd Edition

edited by

Zhuangqiang Gao

submission deadline 15 Jun 2026 | 3 articles | Viewed by 4118 | Submission Open

Keywords: nanostructures; nanomaterials; nanodevices; biosensors; biomarkers; artificial intelligence; in vivo/vitro diagnosis

(This special issue belongs to the Section Biosensor Materials)

Biomedical Applications of Smart Sensors

edited by Sumedha Nitin Prabhu and

Guozhen Liu

submission deadline 15 Jun 2026 | Viewed by 232 | Submission Open

Keywords: biomedical smart sensors; prognostic; prophylactic; point-of-care

(This special issue belongs to the Section Biosensors and Healthcare)

AI/ML-Enabled Biosensing: Shaping the Future of Disease Detection

edited by

Krishna Kant

submission deadline 15 Jun 2026 | Viewed by 134 | Submission Open

Keywords: microfluidic sensing; electrochemical bio-sensing; point-of-care diagnostics; precision diagnostics; plasmonic sensing; microfluidic devices; lab-on-chip

(This special issue belongs to the Section Nano- and Micro-Technologies in Biosensors)

Micro and Nano Optic-Based Biosensing Technologies and Strategies—2nd Edition

edited by

Wenchao Zhou

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1784 | Submission Open

Keywords: micro/nano optics biosensors; microfluidics; lab-on-a-chip; Point-of-Care tests; SPR; optical micro/nano fibers; metasurface; nanophotonics

(This special issue belongs to the Section Biosensor Materials)

Sensors for Detection of Virus and Bacteria

edited by

Zhu Chen

submission deadline 20 Jun 2026 | 2 articles | Viewed by 1397 | Submission Open

Keywords: bacteria and viruses; nanomaterials; molecular diagnostics; microfluidics and microsystem; artificial intelligence; electrochemical biosensors; optical chemical biosensor

Surface-Enhanced Raman Scattering in Biosensing Applications

edited by

Hrvoje Gebavi

and

Yuling Hu

submission deadline 30 Jun 2026 | 12 articles | Viewed by 39946 | Submission Open

Keywords: SERS substrate development; SERS for biosensing applications; food contaminant detection; environmental pollution control; machine learning (SERS); SERS sensors; quantitative SERS methods; biohazardous molecules; forensic substances

(This special issue belongs to the Section Optical and Photonic Biosensors)

Feature Papers of Biosensors

edited by

Jun-Jie Zhu

and Tingting Zheng

submission deadline 30 Jun 2026 | 8 articles | Viewed by 24269 | Submission Open

Keywords: biosensor; fluorescence; Raman; mechanical transducers; microfabrication; mass spectral transducers; wearable device

Advanced Lab-on-Chip and Micro-Systems for Manipulation and Bio-Detection

edited by

Kai Zhao

and

Kaihuan Zhang

submission deadline 30 Jun 2026 | 2 articles | Viewed by 13933 | Submission Open

Keywords: microfluidics; LOC devices; dielectrophoretic; microfabrication; target manipulation; signal detection; resolution and throughput

(This special issue belongs to the Section Biosensor and Bioelectronic Devices)

Biosensors for Environmental Monitoring and Food Safety

edited by

Jing Wei

and Bingxi Feng

submission deadline 30 Jun 2026 | 7 articles | Viewed by 11490 | Submission Open

Keywords: biosensors; nanozyme; nanomaterials; metal oxide; catalysis; environmental monitoring; food safety

(This special issue belongs to the Section Environmental Biosensors and Biosensing)

Photonics for Bioapplications: Sensors and Technology—2nd Edition

edited by

Nélia Jordão Alberto

Maria de Fátima Domingues

Nunzio Cennamo

and

Adriana Borriello

submission deadline 30 Jun 2026 | 6 articles | Viewed by 10091 | Submission Open

Keywords: optical fiber biosensing; optical fiber immunosensors; new bio/chemical probes for bioapplications; molecular diagnosis; point-of-care devices; biomarker detection; wearable biomedical sensors; optical sensors in e-Health architectures; energy-efficient eHealth architecture; big data analysis for eHealth; plasmonic sensors and interrogation systems; advanced signal processing techniques; photonic integrated circuits (PICs) for bioapplications; imaging sensors; low-cost; miniaturized; selective; and multiparameter photonic devices

(This special issue belongs to the Section Optical and Photonic Biosensors)

Microfluidics for Sample Pretreatment

edited by

Bing Xu

and

Nan Xiang

submission deadline 30 Jun 2026 | 3 articles | Viewed by 7453 | Submission Open

Keywords: sample pretreatment; plasma separation; blood cell separation; exosome isolation; novel microfluidic separation methods; CTC separation

(This special issue belongs to the Section Biosensors and Healthcare)

Advances in Nanopore Biosensors

edited by Ki-baek Jeong, Sathishkumar Munusamy and Muhammad Asad Ullah Khalid

submission deadline 30 Jun 2026 | 1 articles | Viewed by 4219 | Submission Open

Keywords: nanopore; biosensor; single-molecule detection; biological nanopore; solid-state nanopore; disease diagnosis; DNA detection; protein detection; point-of-care nanopore; nanomaterial; functionalized nanopore; sequencing

(This special issue belongs to the Section Biosensor Materials)

Advances in Biosensors Based on Framework Materials

edited by Peng Ren and Xuemei Yang

submission deadline 30 Jun 2026 | 3 articles | Viewed by 3752 | Submission Open

Keywords: metal organic frameworks; covalent organic frameworks; hydrogen-bonded organic frameworks; hybrid frameworks; biosensing; biosensors

(This special issue belongs to the Section Biosensor Materials)

Biosensors for Healthcare and Environment: Current and Future Perspectives

edited by Shuang Zhou,

Shaoqing Dong

Lin Li

and

Yan Zhang

submission deadline 30 Jun 2026 | 4 articles | Viewed by 3003 | Submission Open

Keywords: biosensor; nano-material; optical sensor; biochemical analysis; clinical diagnostics; integration of diagnosis and treatment; bioimaging; nano-enzyme; environmental monitoring

(This special issue belongs to the Section Biosensors and Healthcare)

Fluorescent Probes: Design and Biological Applications

edited by Xiaoyue Han

submission deadline 30 Jun 2026 | 2 articles | Viewed by 1658 | Submission Open

Keywords: fluorescent probe; bioimaging; biosensor

(This special issue belongs to the Section Optical and Photonic Biosensors)

Wearable Sensors and Systems for Continuous Health Monitoring

edited by

Shuang Huang

Yeyun Cai

and

Qiangqiang Ouyang

submission deadline 30 Jun 2026 | 2 articles | Viewed by 1503 | Submission Open

Keywords: wearable sensors; health monitoring; disease biomarkers; electrophysiological signals; blood pressure and cardiovascular monitoring; motion and activity tracking; personalized healthcare

(This special issue belongs to the Section Wearable Biosensors)

Mass Sensitive Biosensors for Biomedical Applications

edited by