Applications of Nanomaterials in Optical and Photonic Biosensors

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Nano- and Micro-Technologies in Biosensors".

Deadline for manuscript submissions: 30 May 2027 | Viewed by 1024

Editors


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Guest Editor
College of Engineering, Huazhong Agricultural University, Wuhan 430070, China
Interests: photonic sensor; optical engineering

Special Issue Information

Dear Colleagues,

Nanomaterials have gained considerable attention for their transformative role in the development of optical and photonic biosensors. Their exceptional optical, electronic, and surface properties provide significant advantages for enhancing sensor performance in a wide range of applications. This Special Issue aims to consolidate state-of-the-art research on the design, synthesis, and application of nanomaterials in optical and photonic biosensors. We invite contributions that address the integration of advanced nanomaterials such as quantum dots, carbon-based nanomaterials, and 2D materials with optical sensing technologies, including surface plasmon resonance (SPR), fluorescence, and Raman spectroscopy. Emphasis is placed on innovative fabrication techniques, interface engineering strategies, and device architectures that contribute to improvements in sensitivity, selectivity, and stability. By presenting the latest developments in this rapidly evolving field, this Special Issue seeks to foster interdisciplinary collaboration and accelerate the translation of nanomaterial-based biosensors from research to practical applications in diagnostics, environmental monitoring, and medical devices.

Dr. Zhengbo Zhu
Dr. Hongwei Lei
Guest Editors

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Keywords

  • nanomaterials
  • optical biosensors
  • photonic biosensors
  • surface plasmon resonance (SPR)
  • quantum dots
  • carbon-based nanomaterials
  • two-dimensional materials
  • biosensing technologies

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Published Papers (1 paper)

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Research

16 pages, 6499 KB  
Article
Manganese-Doped Carbon Dots for Sensitive Fluorescence Detection of Ciprofloxacin in Environmental and Pharmaceutical Samples
by Jian Xue, Wenli Fu, Luhang Liu, Qizhong Qin, Jieying Gao, Yingli Li and Anyi Chen
Biosensors 2026, 16(7), 357; https://doi.org/10.3390/bios16070357 - 26 Jun 2026
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Abstract
A simple and sensitive fluorescence sensing method was developed for ciprofloxacin (CIP) determination based on manganese-doped carbon dots (Mn-CDs). The Mn-CDs were synthesized through a one-step hydrothermal method using anhydrous citric acid and manganese chloride tetrahydrate as precursors. The prepared Mn-CDs exhibited good [...] Read more.
A simple and sensitive fluorescence sensing method was developed for ciprofloxacin (CIP) determination based on manganese-doped carbon dots (Mn-CDs). The Mn-CDs were synthesized through a one-step hydrothermal method using anhydrous citric acid and manganese chloride tetrahydrate as precursors. The prepared Mn-CDs exhibited good dispersibility, uniform nanoscale morphology, abundant surface functional groups and favorable fluorescence properties. The incorporation of Mn was designed to introduce coordination-related binding sites for CIP, thereby enhancing the interaction between Mn-CDs and CIP. Under excitation at 330 nm, the Mn-CDs showed a pronounced fluorescence enhancement response toward CIP, enabling their use as fluorescent probes for quantitative detection. Under the optimized conditions, the fluorescence intensity increased linearly with CIP concentration over the range of 20 nM–10 μM, with a detection limit of 1.12 nM. The proposed sensing system exhibited satisfactory selectivity toward CIP over various potentially interfering substances and good storage stability. The practicality of the method was further verified by analysis of pond water samples, affording recoveries of 86–118% with relative standard deviations below 5%. In addition, the method showed acceptable applicability for CIP determination in different pharmaceutical formulations. These results indicate that the Mn-CD-based fluorescent probe provides a convenient, sensitive and promising platform for CIP determination in environmental and pharmaceutical samples. Full article
(This article belongs to the Special Issue Applications of Nanomaterials in Optical and Photonic Biosensors)
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