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Biosensors
Special Issues
Advances in Biosensors Based on Framework Materials
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Advances in Biosensors Based on Framework Materials

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor Materials".

Deadline for manuscript submissions: 30 September 2025 | Viewed by 248

Special Issue Editors

Dr. Peng Ren

E-Mail Website
Guest Editor
Laboratory of Coordination Chemistry and Functional Materials, Harbin Institute of Technology (Shenzhen), Harbin 150001, China
Interests: metal organic frameworks; catalysis; sensing; gas adsorption; functional olefin polymers
Special Issues, Collections and Topics in MDPI journals
Dr. Xuemei Yang

E-Mail Website
Guest Editor
Laboratory of Coordination Chemistry and Functional Materials, Harbin Institute of Technology (Shenzhen), Harbin 150001, China
Interests: metal organic frameworks; organometallics; enzyme biomimetics; hydrogen production; adsorption and sensing
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Framework materials have been the focus of research for the past 30 years. Among them, the representatives are MOFs (metal organic frameworks), COFs (covalent organic frameworks), and HOFs (hydrogen-bonded organic frameworks). These framework materials have common characteristics, such as a large specific surface area, the variety of structures, the adjustable shape and size of the holes, and the controllable skeleton. They have great applications such as catalysis, adsorption, and sensing. If we search for “Frameworks” and “Biosensors/Biosensing” as keywords in the website, we can find thousands of recent publications. The exploration and development of framework materials for biosensing has obviously emerged as a popular topic of study in recent years, and is of great significance in the chemical, biological, and biomedical fields.

Therefore, for this Special Issue, we welcome original research papers as well as reviews concerning current developments on the advances in biosensors based on framework materials. This includes various frameworks, including MOFs, COFs, HOFs, any hybrid frameworks, and other novel frameworks. Besides the related “wet chemistries”, the theoretical research on predicting the frameworks’ biosensing ability is also encouraged. Any design, development, or new findings regarding framework materials in biosensing are of great interest for the Special Issue. Reviews are also welcome, but please pay more attention to recent advances in biosensors based on framework materials.

Dr. Peng Ren
Dr. Xuemei Yang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • metal organic frameworks
  • covalent organic frameworks
  • hydrogen-bonded organic frameworks
  • hybrid frameworks
  • biosensing
  • biosensors

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Published Papers (1 paper)

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Research

13 pages, 6756 KiB  
Article
Electrochemical Sensor Capable of Enhancing Dopamine Sensitivity Based on Micron-Sized Metal–Organic Frameworks
by Ruhui Yan, Yuewu Zhao, Huaixiao Geng, Mengxia Yan, Jine Wang and Shuang Han
Biosensors 2025, 15(6), 348; https://doi.org/10.3390/bios15060348 (registering DOI) - 30 May 2025
Abstract
Micron-sized, ultrathin metal–organic framework (MOF) sheet is a two-dimensional (2D) hybrid material with a large specific surface area, which can be used not only in the fields of energy and biomedicine, but also in electrode modification to improve the electrochemical detection effect. In [...] Read more.
Micron-sized, ultrathin metal–organic framework (MOF) sheet is a two-dimensional (2D) hybrid material with a large specific surface area, which can be used not only in the fields of energy and biomedicine, but also in electrode modification to improve the electrochemical detection effect. In this work, the 2D-structured Co-TCPP(Fe) MOF sheets were synthesized from porphyrin molecules and cobalt ions and then combined with reduced graphene oxide (rGO) and perfluorosulfonic acid polymer (Nafion) solution to construct Co-TCPP(Fe)/rGO/Nafion-modified electrodes capable of sensitively capturing dopamine (DA). The 2D ultrathin lamellar structure of this electrode-modified material is beneficial to the formation of π-π stacking effect with DA molecules, and the oxygen-containing groups carried on its surface can also form electrostatic attraction with the amino groups of DA molecules. Therefore, the Co-TCPP(Fe)/rGO/Nafion-modified electrode under the synergistic effect shows a specific adsorption effect on DA molecules, resulting in high anti-interference ability and a low detection limit of 0.014 µM in the concentration range of 0.1–100 µM. Furthermore, the Co-TCPP(Fe)/rGO/Nafion composite material composed of micron-sized, ultrathin lamellar structures also shows high reusability due to the stability of its coordination structure and can demonstrate good results when applied to the actual sample detection of human urine. Full article
(This article belongs to the Special Issue Advances in Biosensors Based on Framework Materials)
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