Microfluidics for Sample Pretreatment

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensors and Healthcare".

Deadline for manuscript submissions: 30 June 2026 | Viewed by 6

Special Issue Editors

School of Mechanical Engineering, Suzhou University of Science and Technology, Suzhou 215009, China
Interests: microfluidics; femtosecond laser microfabrication; plasma separation; blood typing; point-of-care testing; open microfluidics; cloth-based microfluidics

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Guest Editor
School of Mechanical Engineering, Southeast University, Nanjing 211189, China
Interests: inertial microfluidics; soft robotics; microfluidic cell separation; viscoelastic microfluidics; point-of-care testing devices; microflow cytometer; microfluidic valve; dielectrophoresis
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Special Issue Information

Dear Colleagues,

In point-of-care testing, sample pretreatment is the first and most key issue for following sample analysis. Due to low sample consumption, high efficiency, small device footprint, low cost, and high manipulation resolution, microfluidic technology has been widely applied for microscale sample pretreatment (blood, sweat, urine, wound exudate, exhaled breath condensate, and so on), such as CTCs’ separation from peripheral blood, plasma separation from the whole blood, blood cells’ separation from other blood components, exosome isolation, sweat extraction, and so on. So far, a variety of progress has already been made in these areas, and several advances are commercialized. However, a high-performance method for sample pretreatment is still highly sought after, as the current methods are still limited in terms of sample separation quality. For example, the plasma yield is still lower in POC plasma separation. Also, the purity, capture efficiency, and viability of CTCs is still limited to meet actual needs. This Special Issue is devoted to elucidating the most recent technical innovations and developments in the area of sample pretreatment through using microfluidic methods. Any contribution in the following sense is welcome to be submitted to this Special Issue. Contributions in the form of reviews and original research papers are welcome.

Topics of interest for this Special Issue include the following:

  • CTCs’ separation via microfluidics;
  • Plasma separation from the whole blood;
  • Blood cells’ separation from other blood components;
  • Exosome isolation;
  • New methods for sample pretreatment;
  • Other liquid sample pretreatment;
  • High-performance microfluidic separation methods;
  • Wound exudate/exhaled breath condensate collection and analysis.

Dr. Bing Xu
Prof. Dr. Nan Xiang
Guest Editors

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Keywords

  • sample pretreatment
  • plasma separation
  • blood cell separation
  • exosome isolation
  • novel microfluidic separation methods
  • CTC separation

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Published Papers

This special issue is now open for submission.
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