Electrochemical Biosensors for Healthcare and Environmental Monitoring: Fundamentals and Applications
A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensors and Healthcare".
Deadline for manuscript submissions: 31 May 2026 | Viewed by 24
Special Issue Editors
Interests: electroanalytical chemistry
Special Issue Information
Dear Colleagues,
The past decade has witnessed revolutionary advances in electrochemical biosensing, driving paradigm shifts in medical diagnostics, environmental monitoring, and pharmaceutical analysis. By leveraging electron-transfer reactions at biorecognition interfaces, electrochemical biosensors achieve rapid, low-cost, and real-time quantification of diverse targets—from disease biomarkers to environmental toxins—with ultrahigh sensitivity and selectivity.
Breakthroughs in nano-engineered electrodes, antifouling interfaces, and signal amplification strategies now enable direct analysis in complex matrices (e.g., blood, wastewater). Innovations such as CRISPR-integrated biosensors, wearable multiplexed platforms, and machine learning-driven data interpretation are accelerating translation to point-of-care diagnostics and precision health.
Despite these strides, critical challenges persist—including electrode stability in physiological environments, reproducibility in mass fabrication, interference suppression in real samples, and seamless integration with microfluidics. This Special Issue seeks cutting-edge research addressing these gaps while expanding the technological frontier.
This Special Issue welcomes original research articles and in-depth reviews addressing all aspects of electrochemical biosensors and their translation to various applications. Topics of interest include, but are not limited to the following:
- Fundamental Mechanisms: Electron-transfer kinetics, bio-nano interface engineering, in situ characterization.
- Materials Innovation: Nanostructured electrodes (MXenes, MOFs), stimuli-responsive polymers, and biomimetic catalysts.
- Detection Paradigms: CRISPR-based biosensing, aptamer/antibody engineering, and amplification-free strategies.
- System Integration: Wearable/implantable sensors, lab-on-chip platforms, wireless data transmission.
- Applications: Real-time pathogen detection, continuous biomarker monitoring, on-site environmental sensing.
We encourage contributions on the following:
- Novel methodologies enhancing sensitivity/selectivity.
- Scalable manufacturing and device stability validation.
- AI-powered signal processing and portable reader designs.
- Clinical/field validation studies demonstrating real-world impact.
Dr. Shuang Han
Dr. Yuewu Zhao
Guest Editors
Manuscript Submission Information
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Keywords
- electrochemical biosensors
- bio-nano interfaces
- electron-transfer kinetics
- CRISPR-based diagnostics
- amplification-free detection
- antifouling interfaces
- wearable electrochemical sensors
- lab-on-a-chip platforms
- real-time pathogen monitoring
- continuous biomarker analysis
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