Interdisciplinary Advances: Lab-on-a-Chip Biosensors Shaping Precision Diagnosis
A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Nano- and Micro-Technologies in Biosensors".
Deadline for manuscript submissions: 31 May 2026 | Viewed by 7
Special Issue Editors
Interests: micro/nanofluidics; microfabrication; lab-on-a-chip; 3D-printing; MEMS; biosensing
Special Issue Information
Dear Colleagues,
Lab-on-a-Chip (LOC) technology enables the miniaturization and integration of diverse laboratory processes, including chemical analysis and biomarker detection, onto compact microfluidic chips. By combining microfluidics, biomedical micro-electromechanical systems (bio-MEMS), and micro total analysis systems (µTAS), LOC platforms offer precise control of fluids and reactions at the micro/nanoscale, enabling more rapid, precise, and cost-effective diagnostics for clinical and biochemical applications. In recent years, LOC biosensors and their associated microsystems, including bio-MEMS and μTAS, have emerged as transformative tools for precision diagnosis, supporting applications such as pathogens detection, cancer diagnostics, drug discovery, and personalized medicine. These devices leverage complementary technologies developed across interdisciplinary fields, including chemistry, biology, physics, materials science, and computer science, to enhance chip programmability, integration, sensitivity, and specificity. Coupling LOC biosensors with artificial intelligence (AI) technologies opens new opportunities for signal processing, data interpretation, and decision support in clinical contexts.
This Special Issue, “Interdisciplinary Advances: Lab-on-a-Chip Biosensors Shaping Precision Diagnosis,” invites contributions that highlight novel designs, fabrication methods, and interdisciplinary approaches aimed at enhancing LOC biosensor performance and translating these technologies into practical healthcare solutions.
Topics of interest include, but are not limited to, the following:
- Innovative LOC designs and microfluidic architectures: bio-MEMS, µTAS, and 3D-printed microdevices
- Next-generation biosensor performance: enhanced sensitivity, specificity, multiplexing, and miniaturization
- Clinical and biomedical applications: pathogen detection, cancer biomarkers, drug screening, and personalized medicine
- Advanced technology integration: AI, machine learning, Internet of Things (IoT), and portable biosensing platforms
- Translational and interdisciplinary approaches: combining chemistry, biology, physics, materials science, and computational modeling to accelerate real-world impact
We are excited to receive your contributions and to highlight this groundbreaking research to the scientific community.
Dr. Xinye Chen
Dr. Ke Du
Guest Editors
Manuscript Submission Information
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Keywords
- lab-on-a-chip
- microfluidics
- biosensors
- diagnosis
- artificial intelligence
- bio-MEMS
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