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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advanced Research in Mitochondrial Medicine and Nanomedicine

edited by

Agnieszka Pyrczak-Felczykowska

submission deadline 31 Aug 2026 | Viewed by 495 | Submission Open

Keywords: nanomedicine; nanoparticles; drug delivery; mitochondria; cancer; neurodegenerative disease; metabolism; targeted therapy; mitochondrial function; bioactive compounds

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Advancements in Research on Pancreatic Cancer: From Biomarkers to Targeted Therapies

edited by

Konstantinos Dimas

submission deadline 31 Aug 2026 | Viewed by 477 | Submission Open

Keywords: pancreatic cancer; novel biomarkers; diagnostic techniques; therapeutic approaches

(This special issue belongs to the Section Cancer Biology and Oncology)

Feature Review: Advanced Manufacturing, Biomaterials, and Stem Cells for Tissue and Regenerative Engineering

edited by

Roozbeh Ross Salary

submission deadline 31 Aug 2026 | Viewed by 472 | Submission Open

Keywords: advanced manufacturing; biomaterials; tissue engineering; regenerative medicine

(This special issue belongs to the Section Biomedical Engineering and Materials)

New Advances in Neuroprotective Agents

edited by

Mariano Catanesi

submission deadline 31 Aug 2026 | Viewed by 443 | Submission Open

Keywords: mitochondrial disfunction; antioxidant molecules; gene therapy; stem cell; nanomedicine; cellular reprogramming

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Nanoparticles for Glioblastoma Therapy

edited by Shambhavi Pandey and

Benjamí Oller-Salvia

submission deadline 31 Aug 2026 | Viewed by 400 | Submission Open

Keywords: nanoparticles; blood– brain barrier; gene delivery; glioblastoma; cancer stem cells; biomaterials

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Intestinal Homeostasis and Disease Dysbiosis

edited by

Nikolas Dovrolis

submission deadline 31 Aug 2026 | Viewed by 380 | Submission Open

Keywords: gut microbiota; intestinal homeostasis; dysbiosis; microbiota–drug interactions; host–microbe interactions; microbiome therapeutics; precision medicine

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Advances in Research in Sarcopenia

edited by

Claudio Cabello-Verrugio

submission deadline 31 Aug 2026 | Viewed by 371 | Submission Open

Keywords: aging and muscle deterioration; secondary sarcopenia; metabolic diseases and sarcopenia; pathogen-induced muscle alterations; chronic disease-associated muscle loss; inflammatory sarcopenia mechanisms; sarcopenia biomarkers and diagnosis; therapeutic interventions; exercise and sarcopenia; muscle wasting syndromes; age-related frailty

(This special issue belongs to the Section Molecular and Translational Medicine)

Engineering Extracellular Matrix (ECM)-Based Scaffold Biomaterials for Cancer Treatment

edited by

Sanjay Pal

submission deadline 31 Aug 2026 | Viewed by 365 | Submission Open

Keywords: extracellular matrix; biomaterials; immunomodulatory agents; cancer immunotherapy; sustained delivery; drug delivery; tumor modeling; 3D model; therapeutic response; decellularized ECM

(This special issue belongs to the Section Gene and Cell Therapy)

Tumor Microenvironment in Head and Neck Squamous Cell Carcinoma

edited by Julia Federspiel,

Teresa Steinbichler

and

Jozsef Dudas

submission deadline 31 Aug 2026 | Viewed by 356 | Submission Open

Keywords: head and neck oncology 3D tumor models; cancer-associated fibroblasts; phototherapy; exosomes

(This special issue belongs to the Section Cancer Biology and Oncology)

Antibody Responses to Viral Infections: Insights from Structural Biology

edited by Pragati Agnihotri and

Sharanbasappa Karade

submission deadline 31 Aug 2026 | Viewed by 356 | Submission Open

Keywords: crystal structure; virus–antibody complexes; broadly neutralizing antibodies; immunology; epitope mapping

(This special issue belongs to the Section Microbiology in Human Health and Disease)

From Cell Dysfunction to Prothrombotic Disorders: Molecular Pathways and Clinical Implications

edited by

Cristina Barale

submission deadline 31 Aug 2026 | Viewed by 352 | Submission Open

Keywords: prothrombotic disorder; cellular dysfunction; hemostatic balance; thrombosis; novel biomarkers; antithrombotic therapies

(This special issue belongs to the Section Cell Biology and Pathology)

Advances in Chondrocyte Biology (2nd Edition)

edited by

Bo Qiu

submission deadline 31 Aug 2026 | Viewed by 332 | Submission Open

Keywords: osteoarthritis; chondrocyte; differentiation; proliferation; signaling pathways; transcription factor; inflammation; cellular processes; cartilage repair

(This special issue belongs to the Section Cell Biology and Pathology)

Emerging Trends in Head and Neck Squamous Cell Carcinoma

edited by Sagar Kansara and

Vlad Sandulache

submission deadline 31 Aug 2026 | Viewed by 313 | Submission Open

Keywords: head and neck cancer; head and neck squamous cell carcinoma; immunotherapy; multi-omics; machine learning; precision medicine

(This special issue belongs to the Section Cancer Biology and Oncology)

Precision Diagnosis, Novel Mechanisms and Targeted Therapy for Autoimmune Encephalitis

edited by

Sheng Chen

submission deadline 31 Aug 2026 | Viewed by 312 | Submission Open

Keywords: autoimmune encephalitis; neuronal autoantibodies; biomarkers; animal models; immunopathogenesis; PET/MRI; immunotherapy

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Tumor Immune Microenvironment and Immune Escape Mechanisms in Cancer Progression and Therapy

edited by Yadong Guo

submission deadline 31 Aug 2026 | Viewed by 293 | Submission Open

Keywords: tumor immune evasion; immune checkpoint regulation; tumor microenvironment; immunotherapy response and prognosis

(This special issue belongs to the Section Cancer Biology and Oncology)

Oncolytic Viruses and Combinatorial Immunotherapy for Cancer (2nd Edition)

edited by

Zong Sheng Guo

and

Michael H. Lehmann

submission deadline 31 Aug 2026 | Viewed by 290 | Submission Open

Keywords: oncolytic virus; antitumor immunity; cold tumor; tumor antigen; cancer vaccine; immunotherapy; combinatorial therapy; immune checkpoint blockade

(This special issue belongs to the Section Immunology and Immunotherapy)

Innovative Anticancer Agents: Design, Synthesis and Pharmacological Evaluation

edited by

Sreenivasan Sasidharan

submission deadline 31 Aug 2026 | Viewed by 277 | Submission Open

Keywords: anticancer agents; drug design; pharmacological evaluation; structure–activity relationship; molecular docking; apoptosis; phytochemicals; oxidative stress; targeted therapy; natural products

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Innovative Approaches to Molecular Pathogenesis and Therapy of Lymphoid Malignancies: 2nd Edition

edited by

Sara Elgamal

and

Dalia El-Gamal

submission deadline 31 Aug 2026 | Viewed by 268 | Submission Open

Keywords: lymphoma; leukemia; myeloma; lymphoproliferative disorders; B-cell neoplasms; T-cell neoplasms; pathogenesis; molecular targets; novel therapies; translational research; tumor microenvironment

(This special issue belongs to the Section Cell Biology and Pathology)

CAR T-Cell Therapy in Solid Tumors

edited by

Luigi Liguori

submission deadline 31 Aug 2026 | Viewed by 244 | Submission Open

Keywords: CAR T cell; combinatorial strategies; immunotherapy; resistance; solid tumors; tumor microenvironment; tumor antigen

(This special issue belongs to the Section Cancer Biology and Oncology)

Brain Tumors: From Pathophysiology to Novel Diagnostic and Therapeutic Approaches

edited by Emma van Kessel, Sharon Berendsen and Pierre A. Robe

submission deadline 31 Aug 2026 | Viewed by 204 | Submission Open

Keywords: brain tumors; glioma; brain metastases; neuro-oncology; cognition; liquid biopsy; biomarkers; tumor biology; translational research

(This special issue belongs to the Section Cancer Biology and Oncology)

Advanced Research in Metabolic Syndrome (2nd Edition)

edited by

Balazs Varga

submission deadline 11 Sep 2026 | 4 articles | Viewed by 7277 | Submission Open

Keywords: obesity; diabetes; dyslipidemia; hypertension; microcirculatory damage; ischemia–reperfusion; necro-apopto-autophagy; laboratory animals; bioactive agents

(This special issue belongs to the Section Cell Biology and Pathology)

Biomarkers and Therapeutic Targets in Gastric Cancer: From Basic Research to Clinical Applications

edited by

Laura Georgiana Necula

submission deadline 11 Sep 2026 | 2 articles | Viewed by 4357 | Submission Open

Keywords: gastric cancer; tumor microenvironment; gastric cancer metastasis; cancer stem cells; diagnosis and treatment; biomarkers

(This special issue belongs to the Section Cancer Biology and Oncology)

Trends in 3D Printing Processes for Biomedical Field: Opportunities and Challenges (2nd Edition)

edited by

M. R. Mozafari

submission deadline 15 Sep 2026 | 2 articles | Viewed by 9770 | Submission Open

Keywords: 3D/4D bioprinting techniques; 3D bioprinting processes; 3D cellular microenvironment; bio-inks; hydrogels

(This special issue belongs to the Section Biomedical Engineering and Materials)

Prostate Cancer Pathology: Recent Advances and Future Perspectives

edited by

Kostis Gyftopoulos

submission deadline 15 Sep 2026 | 3 articles | Viewed by 5314 | Submission Open

Keywords: prostate cancer; pathology; digital pathology; Gleason grading; molecular biomarkers; precision medicine; molecular pathology; molecular profiling; therapy resistance

(This special issue belongs to the Section Cancer Biology and Oncology)

New Perspectives in the Treatment of Head and Neck Vascular Malformations

edited by Paolo Gennaro

submission deadline 18 Sep 2026 | 1 articles | Viewed by 3453 | Submission Open

Keywords: vascular anomalies; vascular malformations; AVMs; venous malformations; electrosclerotherapy

(This special issue belongs to the Section Molecular and Translational Medicine)

Emerging Trends in Cancer: Biomarkers, Therapeutic Strategies and Future Directions

edited by Nedime Serakinci

submission deadline 25 Sep 2026 | 4 articles | Viewed by 2675 | Submission Open

Keywords: cancer biomarkers; stem cells; personalized medicine; emerging cancer therapies; tumor microenvironment

(This special issue belongs to the Section Cancer Biology and Oncology)

Obstructive Sleep Apnea: Mechanisms, Comorbidities, and Optimization of Emerging and Established Therapies

edited by

Ivana Pavlinac Dodig

and

Renata Pecotic

submission deadline 29 Sep 2026 | 11 articles | Viewed by 20927 | Submission Open

Keywords: obstructive sleep apnea; sleep-disordered breathing; pathophysiology; cardiometabolic comorbidities; precision medicine; CPAP; sleep diagnostics; biomarkers; neurocognitive impairment; new therapies

(This special issue belongs to the Section Molecular and Translational Medicine)

Innovations in Bone and Craniofacial Tissue Engineering: From Biomaterials and Mechanobiology to Clinical Applications

edited by Zhekai Hu

submission deadline 29 Sep 2026 | 3 articles | Viewed by 3242 | Submission Open

Keywords: bone tissue engineering; craniofacial regeneration; biomaterials and scaffolds; stem cells and exosomes; mechanobiology and orthodontic forces; osteoimmunology; oxidative stress modulation; gene/drug delivery; translational research; periodontal and alveolar bone regeneration

(This special issue belongs to the Section Biomedical Engineering and Materials)

Pathology, Complications and Prognosis of Type 1 Diabetes

edited by Maurizio Delvecchio

submission deadline 29 Sep 2026 | 1 articles | Viewed by 1726 | Submission Open

Keywords: type 1 diabetes mellitus; autoimmune β-cell destruction; diabetic complications; microvascular and macrovascular damage; diabetic ketoacidosis; glycemic control; disease prognosis; immunopathogenesis

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Nervous System Diseases: From Pathophysiology to Novel Therapeutic Approaches

edited by Natalia Rozas and Cameron Jeter

submission deadline 30 Sep 2026 | 9 articles | Viewed by 35795 | Submission Open

Keywords: neurodegenerative diseases; neuromuscular diseases; autoimmune diseases of the nervous system; brain diseases; neuroinflammatory diseases; neuromuscular diseases; trauma of the nervous system

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Diabetes: Comorbidities, Therapeutics and Insights (3rd Edition)

edited by

Tomislav Bulum

submission deadline 30 Sep 2026 | 9 articles | Viewed by 22618 | Submission Open

Keywords: diabetes; complications; diabetic retinopathy; diabetic neuropathy; diabetic nephropathy; biomarkers

(This special issue belongs to the Section Molecular and Translational Medicine)

Nephrotic Syndrome: Pathomechanism, Diagnostics and Novel Treatment Options—2nd Edition

edited by

Kan Katayama

submission deadline 30 Sep 2026 | 5 articles | Viewed by 18955 | Submission Open

Keywords: focal segmental glomerulosclerosis; genetic kidney disease; minimal change disease; nephrotic syndrome; podocyte

(This special issue belongs to the Section Molecular and Translational Medicine)

Hypertension and Chronic Renal Failure

edited by

Caterina Carollo

submission deadline 30 Sep 2026 | 4 articles | Viewed by 17420 | Submission Open

Keywords: hypertension; chronic renal failure; NephroCardiology

(This special issue belongs to the Section Molecular and Translational Medicine)

Parkinson’s Disease: Where Are We and Where Are We Going To

edited by Carmen Borrué

submission deadline 30 Sep 2026 | 1 articles | Viewed by 17273 | Submission Open

Keywords: Parkinson’s disease; gait disorders; biomarkers; neurodegenerative disease; AI

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Gynecological Diseases in Cellular and Molecular Perspectives

edited by

Iwona Wertel

and

Anna Pawłowska-Łachut

submission deadline 30 Sep 2026 | 7 articles | Viewed by 16637 | Submission Open

Keywords: gynaecological diseases; endometriosis; biomarkers; immune checkpoints; immunotherapy; tumor microenvironment; tumor-infiltrating immune cells; cancer immunology; cellular interactions

(This special issue belongs to the Section Molecular and Translational Medicine)

Role of Glycomics in Health and Diseases

edited by

Tijl Vermassen

submission deadline 30 Sep 2026 | 4 articles | Viewed by 15890 | Submission Open

Keywords: glycomics; protein chemistry; immunology; biomarker research

(This special issue belongs to the Section Molecular and Translational Medicine)

Advancements in the Treatment of Colorectal Cancer

edited by

Andee Dzulkarnaen Zakaria

submission deadline 30 Sep 2026 | 8 articles | Viewed by 14559 | Submission Open

Keywords: genomic profiling; advanced nutritional support; AI; MDT; adjuvant therapy

(This special issue belongs to the Section Cancer Biology and Oncology)

New Advances in Chronic Kidney Disease: Biology, Diagnosis and Therapy (3rd Edition)

edited by

Susana Coimbra

and

Alice Santos-Silva

submission deadline 30 Sep 2026 | 11 articles | Viewed by 12448 | Submission Open

Keywords: inflammation; kidney biomarkers; kidney injury; chronic kidney disease; dialysis; cardiorenal syndrome risk; CKD anemia; kidney physiopathology; CKD treatment

(This special issue belongs to the Section Cell Biology and Pathology)

The Molecular Basis of the Immune Response in Pulmonary Fibrosis

edited by

Tamara Cruz

and

Fernanda Hernandez

submission deadline 30 Sep 2026 | 3 articles | Viewed by 11172 | Submission Open

Keywords: immune response; fibrosis; aging; senescence

(This special issue belongs to the Section Immunology and Immunotherapy)

Molecular Research in Ocular Pathology

edited by

Sorin Lucian Bolintineanu

and

Laura Andreea Ghenciu

submission deadline 30 Sep 2026 | 5 articles | Viewed by 10967 | Submission Open

Keywords: molecular pathology; ocular diseases; biomarkers; diabetic retinopathy; glaucoma; age-related macular degeneration; thyroid eye disease; inflammatory pathways; oxidative stress; angiogenesis; neurodegeneration; gene therapy; cell therapy; precision medicine; ocular imaging

(This special issue belongs to the Section Molecular and Translational Medicine)

State-of-the-Art Neonatal Medicine in Japan

edited by

Fumihiko Namba

submission deadline 30 Sep 2026 | 4 articles | Viewed by 10546 | Submission Open

Keywords: mesenchymal stromal cells; artificial placenta; therapeutic gasses; animal models; off-label drug use

(This special issue belongs to the Section Molecular and Translational Medicine)

Skin Diseases and Cell Therapy

edited by Nives Pondeljak, Maryam Heidari Kharaji and Mirna Šitum

submission deadline 30 Sep 2026 | 3 articles | Viewed by 9675 | Submission Open

Keywords: dermatology; psoriasis, atopic dermatitis, vitiligo, alopecia, cutaneous leishmaniasis, and skin fibrosis; skin cancers; innovative therapeutic strategies; molecular mechanisms

(This special issue belongs to the Section Gene and Cell Therapy)

Feature Reviews in Biomaterials for Oral Diseases

edited by

Oliver Schierz

submission deadline 30 Sep 2026 | 3 articles | Viewed by 9390 | Submission Open

Keywords: dental composites; ceramics; zirconia; polymers; polyaryletherketone; polyoxymethylene; titanium; bone graft materials; implants

(This special issue belongs to the Section Biomedical Engineering and Materials)

Next-Generation Nanoparticles: Innovations in Biomedical Applications and Theranostics

edited by

Md Amdadul Huq

submission deadline 30 Sep 2026 | 1 articles | Viewed by 6495 | Submission Open

Keywords: nanoparticles; nanoconjugates; antimicrobial agents; anticancer agents; biomedical applications

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Drug Delivery and Nanocarrier

edited by

Jiawei Huo

submission deadline 30 Sep 2026 | 5 articles | Viewed by 6369 | Submission Open

Keywords: nanocarriers; targeted drug delivery; controlled release; theranostics; biocompatibility; functionalized nanoparticles; nanomedicine; translational nanotechnology

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Cardiomyopathies and Heart Failure: Charting the Future—2nd Edition

edited by Ali Amr

submission deadline 30 Sep 2026 | 3 articles | Viewed by 6289 | Submission Open

Keywords: cardiomyopathies; heart failure; risk stratification; management of cardiomyopathies; cardiac imaging; telemedicine

(This special issue belongs to the Section Cell Biology and Pathology)

New Advances in Insulin—100 Years Since Its Discovery: 2nd Edition

edited by

Tomislav Bulum

submission deadline 30 Sep 2026 | 4 articles | Viewed by 5933 | Submission Open

Keywords: insulin action; insulin analogs; type 1 diabetes; type 2 diabetes; complications; glucose homeostasis

(This special issue belongs to the Section Cell Biology and Pathology)

The Gut Microbiome in Early Life and Beyond: Implications for Health and Disease

edited by

Ye Peng

and

Shilan Wang

submission deadline 30 Sep 2026 | 3 articles | Viewed by 5804 | Submission Open

Keywords: gut microbiome; early-life development; DOHaD; microbial dysbiosis; chronic disease; probiotics; prebiotics; microbiome–host interactions; developmental programming; translational research

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Extracellular Vesicles and Exosomes as Therapeutic Agents—2nd Edition

edited by

David J. Rademacher

submission deadline 30 Sep 2026 | 2 articles | Viewed by 5782 | Submission Open

Keywords: extracellular vesicles; exosomes; therapeutics; drug delivery; bioengineering

(This special issue belongs to the Section Cell Biology and Pathology)

Integrative Roles of Natural Products in Cancer Treatment and Chronic Inflammatory Disease

edited by

Seungho Baek

submission deadline 30 Sep 2026 | 5 articles | Viewed by 5307 | Submission Open

Keywords: natural products; cancer; chronic inflammatory diseases; therapy; oxidative stress

(This special issue belongs to the Section Molecular and Translational Medicine)

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