Special Issues

Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Novel Progress in Cancer Immunotherapy
edited by
submission deadline 31 Jul 2025 | 1 articles | Viewed by 1226 | Submission Open
Keywords: immune checkpoint blockers; CAR-T; solid tumor; liquid tumor; cancer therapy; immunology
(This special issue belongs to the Section Cancer Biology and Oncology)
Animal Models of Neurological Disorders: Where Are We Now? (3rd Edition)
edited by
submission deadline 31 Jul 2025 | 1 articles | Viewed by 1205 | Submission Open
Keywords: animal model of neurological disorders; Parkinson’ s disease; Alzheimer’ s disease; epilepsy; seizures; Huntington’ s disease; schizophrenia
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Microcirculation, Thrombosis, and Inflammation in Peripheral Artery Disease and in the Brain submission deadline 31 Jul 2025 | 2 articles | Viewed by 1150 | Submission Open
Keywords: microcirculation; thrombosis; inflammation; peripheral artery disease; brain
(This special issue belongs to the Section Molecular and Translational Medicine)
Rheumatology Diseases: Advances in the Understanding of Pathogenesis, Biomarker Research and Treatment Target
edited by Russka Shumnalieva
submission deadline 31 Jul 2025 | 2 articles | Viewed by 1092 | Submission Open
Keywords: pathogenesis of rheumatic diseases; epigenetic modifications; biomarkers; new imaging modalities; therapeutic strategies; new treatment targets
(This special issue belongs to the Section Molecular and Translational Medicine)
New Insights into the Diagnosis and Treatment of Breast Cancer submission deadline 31 Jul 2025 | 1 articles | Viewed by 1067 | Submission Open
Keywords: Breast cancer; prognostic; medical imaging; chemotherapy; immunotherapy; diagnostics; screening
(This special issue belongs to the Section Cancer Biology and Oncology)
Biomarkers and Therapeutic Targets in Gastric Cancer: From Basic Research to Clinical Applications submission deadline 31 Jul 2025 | 1 articles | Viewed by 949 | Submission Open
Keywords: gastric cancer; tumor microenvironment; gastric cancer metastasis; cancer stem cells; diagnosis and treatment; biomarkers
(This special issue belongs to the Section Cancer Biology and Oncology)
State-of-the-Art Molecular and Translational Medicine in Japan
edited by
submission deadline 31 Jul 2025 | 1 articles | Viewed by 937 | Submission Open
Keywords: molecular and translational research; targeting inflammatory cytokines; targeted drugs; skin diseases; basic mechanisms; novel therapies
(This special issue belongs to the Section Molecular and Translational Medicine)
New Insights in Hypoxic Response Modulation
edited by Rafał Bartoszewski
submission deadline 31 Jul 2025 | 1 articles | Viewed by 915 | Submission Open
Keywords: hypoxia; oxygen homeostasis; oxidative damage; cell death; ischemic events; stroke; myocardial infarction; tumor microenvironment (TME); noncoding RNA; MicroRNAs; long noncoding RNAs; PiRNA; hypoxia-inducible factors (HIFs); targeted delivery; hypoxic cells; regulatory networks; therapeutic opportunities
(This special issue belongs to the Section Cell Biology and Pathology)
Noncoding RNAs (ncRNAs): The Role in Gene Regulation and Human Diseases
edited by and
submission deadline 31 Jul 2025 | Viewed by 774 | Submission Open
Keywords: ncRNAs; genomic editing; epigenetics; stem cell biology and regenerative medicine
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
New Trends in Cancer Immunotherapy
edited by Markella Zannikou
submission deadline 31 Jul 2025 | Viewed by 687 | Submission Open
Keywords: tumor microenvironment; cancer vaccines; tumor-infiltrating lymphocytes; combination therapy; BITEs; checkpoint inhibitors; CAR T cell therapy; NK cells; antigen presenting cells; tumor associated antigens
(This special issue belongs to the Section Immunology and Immunotherapy)
Autophagy, Apoptosis and Cancer: 2025 Update
edited by
submission deadline 31 Jul 2025 | Viewed by 652 | Submission Open
Keywords: autophagy; apoptosis; glioblastoma; hypoxia-inducible factors (HIFs); female fertility and ovarian cancer; nanoparticle-based drug delivery; bioactive natural products
(This special issue belongs to the Section Cancer Biology and Oncology)
Application of Biomedical Materials in Cancer Therapy
edited by Rui Sang
submission deadline 31 Jul 2025 | 1 articles | Viewed by 635 | Submission Open
Keywords: biomedical materials; cancer therapy; drug delivery systems; biomaterials synthesis; imaging agents; tissue engineering; regenerative medicine; tumor microenvironment; targeted therapy; biocompatibility
(This special issue belongs to the Section Biomedical Engineering and Materials)
Role of Oxidized Lipids in Cardiovascular Diseases
edited by
submission deadline 31 Jul 2025 | Viewed by 533 | Submission Open
Keywords: oxidized lipids; antioxidants; fatty acids; lipoproteins; atherosclerosis; cardiovascular disease; inflammation; oxysterol; macrophages; endothelial dysfunction; smooth muscle cell; proliferation
(This special issue belongs to the Section Molecular and Translational Medicine)
Immunosuppressive Treatment in Glomerular Diseases
edited by Henry H.L. Wu and Rajkumar Chinnadurai
submission deadline 31 Jul 2025 | Viewed by 469 | Submission Open
Keywords: immunosuppressive treatment; glomerular diseases; nephrology
(This special issue belongs to the Section Immunology and Immunotherapy)
Molecular Diagnostics and Monitoring in Tuberculosis
edited by Yi-Wei Tang and
submission deadline 31 Jul 2025 | Viewed by 418 | Submission Open
Keywords: tuberculosis; line probe assays; mycobacterial culture; phenotypic susceptibility testing; real-time PCR; whole-genome sequencing; omics techniques
(This special issue belongs to the Section Molecular and Translational Medicine)
Innate Immunity Orchestration in Lung Health and Diseases, 2nd Edition
edited by
submission deadline 31 Jul 2025 | Viewed by 322 | Submission Open
Keywords: innate immune cells; neutrophils; NETs; NETosis; macrophages; phagocytosis; innate lymphoid cells; epithelial cells; lung inflammation; lung cancer; immunotherapy
(This special issue belongs to the Section Immunology and Immunotherapy)
Recent Advances in Primary and Relapsed Ovarian Cancer
edited by Cornelia Bachmann
submission deadline 31 Jul 2025 | Viewed by 313 | Submission Open
Keywords: ovarian cancer; relapse; BRCA; genetics; immunotherapy; biomarkers
(This special issue belongs to the Section Cancer Biology and Oncology)
Role of Microbiota in Colonic Inflammation and Colon Cancer
edited by
submission deadline 31 Jul 2025 | Viewed by 311 | Submission Open
Keywords: microbiota; colon inflammation; colon cancer; molecular mechanism; clinical treatment
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Advances in Therapeutics for Retinal Degeneration
edited by
submission deadline 31 Jul 2025 | Viewed by 300 | Submission Open
Keywords: neuroinflammation; apoptosis; metabolic and oxidative stress; neuroprotection; molecular and cellular pathways; therapeutic strategies; molecular and cellular targets
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances of Amyloid-β Dynamics in Health and Diseases
edited by
submission deadline 31 Jul 2025 | Viewed by 270 | Submission Open
Keywords: Alzheimer’ s disease (AD); amyloid-β clearance; brain and periphery; cerebral amyloid angiopathy (CAA)
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Innovations in Nanomedicine for Disease Management
edited by Anna Valentino and
submission deadline 31 Jul 2025 | Viewed by 264 | Submission Open
Keywords: nanomedicine; nanoparticles; smart drug delivery; personalized medicine; minimally invasive treatments; gene therapy; regenerative medicine
(This special issue belongs to the Section Nanomedicine and Nanobiology)
Demyelinating Diseases: Pathophysiology and Emerging Therapeutic Targets
edited by Jude Taylor
submission deadline 31 Jul 2025 | Viewed by 222 | Submission Open
Keywords: demyelinating diseases; pathophysiological processes; diagnostic accuracy and predicting disease; emerging strategies
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Diabetes Mellitus: Pharmacological Innovations and Related Therapeutic Benefits submission deadline 31 Jul 2025 | Viewed by 197 | Submission Open
Keywords: therapy of diabetes mellitus; pharmacological innovations; incretins; GLP-1 receptor agonists; SGLT-2 inhibitors; weight control; diabetes-related cardiovascular risk; non-glycemic benefits of diabetes drugs; diabetes-related technologies; diabetes outcomes
(This special issue belongs to the Section Molecular and Translational Medicine)
The Renin–Angiotensin System in Immune Regulation: Roles in Blood, Vessels, and Inflammation
edited by Chao Liu
submission deadline 31 Jul 2025 | Viewed by 178 | Submission Open
Keywords: renin– angiotensin system; immune regulation; vascular biology; inflammation; T cells; macrophages; neutrophils; angiotensin II; ACE2; stem cells
(This special issue belongs to the Section Immunology and Immunotherapy)
Novel Strategies for Oncogene-Addicted Lung Cancers: Not Rare Anymore submission deadline 31 Jul 2025 | Viewed by 169 | Submission Open
Keywords: target therapy; EMT; biomarkers; cancer mutations; preclinical models
(This special issue belongs to the Section Cancer Biology and Oncology)
Advances in Head and Neck Cancer: Mechanisms, Diagnosis, and Therapeutic Progress
edited by and Hideto Saijo
submission deadline 31 Jul 2025 | Viewed by 144 | Submission Open
Keywords: head and neck cancer; oral cancer; laryngeal cancer; nasopharyngeal cancer; thyroid cancer; diagnostic and treatment strategies
(This special issue belongs to the Section Cancer Biology and Oncology)
Current Trends in Diabetic Foot Disease
edited by Xuefeng Yu
submission deadline 31 Jul 2025 | Viewed by 131 | Submission Open
Keywords: diabetes; diabetic foot; endocrinology; metabolic disease
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Advances in Precision Cancer Therapy
edited by
submission deadline 31 Jul 2025 | Viewed by 131 | Submission Open
Keywords: personalized cancer therapy; targeted therapy; immunotherapy; cancer genomics; cancer biomarker; liquid biopsy; CAR-T cell therapy; kinase inhibitor; combination therapy; molecular profiling
(This special issue belongs to the Section Cancer Biology and Oncology)
Biochemical and Molecular Perspectives on Engineered Nanoparticles for Cancer Therapy submission deadline 31 Jul 2025 | Viewed by 118 | Submission Open
Keywords: cancer; oxidative stress; engineered nanoparticles (ENPs); drug delivery; biochemical processes; ferroptosis; apoptosis; cell death; molecular interactions; tumor microenvironment
(This special issue belongs to the Section Cancer Biology and Oncology)
Glioblastoma: From Pathology to Novel Therapeutic Approaches
edited by Carlen A. Yuen
submission deadline 31 Jul 2025 | Viewed by 88 | Submission Open
Keywords: glioblastoma; EGFR; TERT; +7/-10; CAR T-cell therapy; immunotherapy; GammaTile® ; LITT
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Molecular Mechanisms and Therapeutic Approaches for Oral Disorders
edited by , and Simona Santonocito
submission deadline 20 Aug 2025 | 6 articles | Viewed by 7879 | Submission Open
Keywords: oral diseases; drugs; local drug delivery; periodontitis; causal periodontal therapy; oral potential malignant disorders; oral cancer; oral medicine
(This special issue belongs to the Section Molecular and Translational Medicine)
SARS-CoV-2 Infection: Focus on Pathophysiological Characteristics, Complications and Effects of Vaccinations submission deadline 31 Aug 2025 | 4 articles | Viewed by 19736 | Submission Open
Keywords: SARS-CoV-2 complications; SARS-CoV2 prognostic and predictive biomarkers; long COVID-19 and autoimmune disease; COVID-19 and microbiome; artificial intelligence
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Antidepressants: 70 Years submission deadline 31 Aug 2025 | 4 articles | Viewed by 16081 | Submission Open
Keywords: polypharmacology; multi-target drugs; emerging therapeutic targets; repurposing; unipolar depression; bipolar disorder
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
The Role of Chemerin in Human Disease2nd Edition
edited by
submission deadline 31 Aug 2025 | 9 articles | Viewed by 15414 | Submission Open
Keywords: biomarker; chemotaxis; cardiovascular diseases; cancer; chemerin isoforms; CMKLR1; GPR1; CCRL2
(This special issue belongs to the Section Cell Biology and Pathology)
From Molecules to Medicine: Deciphering Obesity and Lipid Metabolism for Translational Insights submission deadline 31 Aug 2025 | 5 articles | Viewed by 15176 | Submission Open
Keywords: obesity; insulin resistance; lipid metabolism; drug discovery
(This special issue belongs to the Section Molecular and Translational Medicine)
State-of-the-Art Molecular and Translational Medicine in Poland, 3rd Edition submission deadline 31 Aug 2025 | 6 articles | Viewed by 13435 | Submission Open
Keywords: molecular medicine; molecular mechanisms; disease pathogenesis; genetic variants; gene expression; epigenetics; metabolic disorders; cancer
(This special issue belongs to the Section Molecular and Translational Medicine)
Inflammaging and Immunosenescence: Mechanisms and Link
edited by
submission deadline 31 Aug 2025 | 5 articles | Viewed by 9960 | Submission Open
Keywords: inflammaging; immunosenescence; autoimmune disease; age-related disease; aging
(This special issue belongs to the Section Immunology and Immunotherapy)
Cellular and Molecular Mechanisms in Gastrointestinal Tract Disease
edited by Felipe Leite De Oliveira
submission deadline 31 Aug 2025 | 5 articles | Viewed by 9941 | Submission Open
Keywords: cellular mechanisms; molecular mechanisms; diagnosis; treatment; experimental models; signaling pathways; comorbidities
(This special issue belongs to the Section Cell Biology and Pathology)
Advances in Fabry Disease: From Molecular Insights to Innovative Therapeutics
edited by and Concetto Sessa
submission deadline 31 Aug 2025 | 6 articles | Viewed by 9447 | Submission Open
Keywords: fabry disease; lysosomal storage disorder; GLA gene mutations; enzyme replacement therapy; chaperone therapy; physical activity; imagining
(This special issue belongs to the Section Molecular and Translational Medicine)
Compounds from Natural Products as Sources for Drug Discovery submission deadline 31 Aug 2025 | 5 articles | Viewed by 9440 | Submission Open
Keywords: natural products; drug discovery; bioactive compounds; medicinal plants; marine natural products; pharmacological screening; pharmacognosy; sustainable drug development; purification techniques; compound isolation
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
mTOR Signaling in Disease and Therapy
edited by Wenjing Yu and
submission deadline 31 Aug 2025 | 5 articles | Viewed by 9002 | Submission Open
Keywords: mTOR signaling; tissue engineering; stem cell; disease; therapy; bone; craniofacial; biomedicine
(This special issue belongs to the Section Molecular and Translational Medicine)
Advanced Research of Stem Cells for Regenerative Medicine submission deadline 31 Aug 2025 | 2 articles | Viewed by 8605 | Submission Open
Keywords: stem cells; regenerative therapy; degenerative diseases; aging; tissue engineering
(This special issue belongs to the Section Molecular and Translational Medicine)
Feature Reviews in Cardiovascular Diseases submission deadline 31 Aug 2025 | 6 articles | Viewed by 8603 | Submission Open
Keywords: cardiovascular diseases; heart failure; cardiac arrhythmias; metabolic syndrome; stroke; pulmonary hypertension; peripheral artery disease (PAD); acute coronary syndrome; myocarditis; pericarditis; valvulopathies
(This special issue belongs to the Section Molecular and Translational Medicine)
High-Risk Pregnancy, Labor and Delivery submission deadline 31 Aug 2025 | 3 articles | Viewed by 8525 | Submission Open
Keywords: preterm labor; labor; delivery; pregnancy
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Cancer Biology and Experimental Anticancer Therapies (2nd Edition)
edited by and
submission deadline 31 Aug 2025 | 7 articles | Viewed by 7396 | Submission Open
Keywords: cancer biology; experimental anticancer therapies; immunotherapy; immunotoxins; signalling pathways; targeted therapies
(This special issue belongs to the Section Cancer Biology and Oncology)
Biomedical and Biochemical Basis of Neurodegenerative Diseases
edited by
submission deadline 31 Aug 2025 | 4 articles | Viewed by 6842 | Submission Open
Keywords: neurodegeneration; personalized medicine; biomarkers; diagnosis; treatment
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Natural Product for the Interventions of Chronic Diseases: From Source to Therapy
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 5953 | Submission Open
Keywords: natural products; chronic diseases; drug discovery; pharmacodynamics; pharmacokinetics; nanotechnology
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Advancements in Artificial Intelligence (AI) for Cancer Genomics and Genetics submission deadline 31 Aug 2025 | 3 articles | Viewed by 5604 | Submission Open
Keywords: artificial intelligence; cancer; genetics; epigenetics; genomics; epigenomics; gene-environment interaction; cancer diagnosis and prognosis; personalized medicine; drug discovery
(This special issue belongs to the Section Cancer Biology and Oncology)
Neuroendocrine Neoplasia and Endocrine Tumors: Pathogenic Features, Prognostic Markers and New Therapeutic Approaches
edited by
submission deadline 31 Aug 2025 | 4 articles | Viewed by 5355 | Submission Open
Keywords: neuroendocrine tumors; endocrine tumors; somatostatin analogues; carcinoid syndrome; PRRT; mTOR inhibitor; lymph node; neuroendocrine marker; hormone; ki67
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Digestive Disorders: Translation and Bridging the Gap Between Research, Diagnosis, and Treatment
edited by Goran Hauser and Goran Poropat
submission deadline 31 Aug 2025 | 5 articles | Viewed by 5131 | Submission Open
Keywords: acute pancreatis; clinical nutrition; metabolic disorders; NAFLD; obesity; DGBA; gut microbiota
(This special issue belongs to the Section Molecular and Translational Medicine)
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