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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Colorectal Cancer: Diagnostic, Pathophysiology and Therapeutic Approaches

edited by

Antonio Biondi

and

Marco Vacante

submission deadline 31 May 2025 | 1 articles | Viewed by 839 | Submission Open

Keywords: colorectal cancer; biomarkers; chemotherapy; immunotherapy; liquid biopsy; endoscopy; surgery; microbiota; screening

(This special issue belongs to the Section Cancer Biology and Oncology)

Therapeutic Antibodies, from Isolation to the Clinic

edited by Hugues Fausther-Bovendo

submission deadline 31 May 2025 | 1 articles | Viewed by 826 | Submission Open

Keywords: therapeutic antibodies; infectious diseases; delivery; biodistribution; pharmacokinetics; antibody gene therapy

(This special issue belongs to the Section Immunology and Immunotherapy)

Current Trends in Regenerative Medicine

edited by

Leonidas Kandilogiannakis

and

Eirini Filidou

submission deadline 31 May 2025 | Viewed by 781 | Submission Open

Keywords: regenerative medicine; stem cells; organoids; tissue engineering; gene therapy; cell therapy; biomaterials; personalized medicine

(This special issue belongs to the Section Gene and Cell Therapy)

Recent Therapeutic Advances in Parkinson’s Disease

edited by

Chieh-Sen Chuang

submission deadline 31 May 2025 | Viewed by 728 | Submission Open

Keywords: Parkinson's disease; disease-modifying therapy; continuous dopaminergic stimulation; non-dopaminergic drugs; deep brain stimulation; drug repurposing; immunotherapies; gene therapies

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Neurodevelopmental and Neuropsychiatric Disorders in Animal Models

edited by Yael Abreu-Villaça

submission deadline 31 May 2025 | 1 articles | Viewed by 624 | Submission Open

Keywords: mood disorder; mental disorder; substance use disorder; autism spectrum disorder (ASD); attention-deficit/hyperactive disorder (ADHD); depression and anxiety disorders; schizophrenia; bipolar disorder; epilepsy; eating disorders

(This special issue belongs to the Section Molecular and Translational Medicine)

Clinical, Radiological, and Molecular Insights into Craniopharyngioma

edited by Ernest Jan Bobeff and

Bartosz Szmyd

submission deadline 31 May 2025 | 1 articles | Viewed by 618 | Submission Open

Keywords: neuro-oncology; brain tumors; skull base; craniopharyngioma; stalk

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Advancements in Cardiac Imaging: Diagnostics, Prognostics, and Therapeutics

edited by Ilaria Dentamaro

submission deadline 31 May 2025 | 1 articles | Viewed by 598 | Submission Open

Keywords: cardiac imaging; echocardiography; cardiovascular magnetic resonance imaging; cardio CT; nuclear cardiology

(This special issue belongs to the Section Molecular and Translational Medicine)

Molecular Mechanisms and Therapy of Gliomas

edited by

Valeria Barresi

submission deadline 31 May 2025 | Viewed by 581 | Submission Open

Keywords: glioma; epigenetic; methylome; therapy; genetic alteration; transcriptomic; proteomic

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Cardiac Arrhythmias and Myocardial Infarction

edited by Yen-Nien Lin

submission deadline 31 May 2025 | Viewed by 455 | Submission Open

Keywords: myocardial infarction; tachyarrhythmia; bradyarrhythmia; ventricular tachycardia/fibrillation; supraventricular tachycardia; atrial fibrillation; arrhythmia substrates; antiarrhythmic treatment; ablation

(This special issue belongs to the Section Molecular and Translational Medicine)

New Advances in Insulin—100 Years Since Its Discovery: 2nd Edition

edited by

Tomislav Bulum

submission deadline 31 May 2025 | Viewed by 420 | Submission Open

Keywords: insulin action; insulin analogs; type 1 diabetes; type 2 diabetes; complications; glucose homeostasis

(This special issue belongs to the Section Cell Biology and Pathology)

CDK Inhibitors: A New Wave of Therapeutic Agents for Human Diseases

edited by Mengqian Chen

submission deadline 31 May 2025 | Viewed by 382 | Submission Open

Keywords: cyclin-dependent kinases (CDKs); cell-cycle CDKs; transcriptional CDKs; CDK inhibitors; CDK degraders; cancer therapeutics; inflammatory diseases; neurodegenerative disorders; pharmacology; clinical trials

(This special issue belongs to the Section Cancer Biology and Oncology)

Liver Fibrosis: Molecular Mechanisms, Potential Therapeutic Targets and Clinical Biomarkers, 2nd Edition

edited by

Takefumi Kimura

submission deadline 31 May 2025 | Viewed by 363 | Submission Open

Keywords: liver fibrosis treatment; therapeutic target biomarker; hepatitis; NAFLD; NASH; MAFLD; HSC; GPCR; immunity cell death

(This special issue belongs to the Section Molecular and Translational Medicine)

Amino Acid Metabolism and Its Role in Cancer Pathogenesis and Treatment

edited by Bo Han and Ba Xuan Hoang

submission deadline 31 May 2025 | Viewed by 355 | Submission Open

Keywords: cancer; oncology; immunology; amino acid metabolism; cancer metabolic reprogramming; nutritional therapy; food supplements

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Neglected Infectious Diseases: From Pathophysiology to Therapy

edited by Raimunda Nonata Ribeiro Sampaio

submission deadline 31 May 2025 | Viewed by 340 | Submission Open

Keywords: pathophysiology; host– parasite infection interactions; diagnostic tools; therapeutic intervention; novel biomarkers

(This special issue belongs to the Section Microbiology in Human Health and Disease)

State-of-the-Art Endocrinology and Metabolism Research in Spain

edited by Zaida Abad-Jiménez and

Teresa Vezza

submission deadline 31 May 2025 | Viewed by 337 | Submission Open

Keywords: endocrinology; metabolism; hormonal regulation; metabolic disorders; biomarkers; therapeutic targets

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Advanced Research on Genitourinary Cancer

edited by Jue Wang

submission deadline 31 May 2025 | Viewed by 333 | Submission Open

Keywords: genitourinary (GU) cancer; prostate; bladder; kidney; and testicular cancer; diagnosis; treatment; pathogenesis; precision medicine; biomarker discovery; genomic profiling

(This special issue belongs to the Section Molecular and Translational Medicine)

Recent Advances in Targeted Drug Delivery Systems

edited by

Santosh Bashyal

submission deadline 31 May 2025 | Viewed by 319 | Submission Open

Keywords: targeted drug delivery systems; nanocarriers (lipid or polymeric); stimuli-responsive carriers; exosomes or exosome-mimetic vesicles; disease targeting; tumor targeting; theranostics

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Feature Reviews in Cytokines

edited by

Monika Zajkowska

submission deadline 31 May 2025 | Viewed by 300 | Submission Open

Keywords: cytokines; neurodegenerative disease; cancer; diabetes; obesity; immunological disorder; cardiovascular disease; diagnosis; biomarker; treatment

(This special issue belongs to the Section Molecular and Translational Medicine)

The Interplay Between miRNA and Mitochondrial Dysfunction in Neurodegenerative Diseases

edited by

Mariano Catanesi

submission deadline 31 May 2025 | Viewed by 296 | Submission Open

Keywords: miRNA; neurodegenerative diseases; mitochondrial dysfunction; aging; gene expression

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

State-of-the-Art Neurobiology and Clinical Neuroscience in the United States

edited by

Justin Miller

and

Laura Ibanez

submission deadline 31 May 2025 | Viewed by 295 | Submission Open

Keywords: neurobiology; neuroscience; bioinformatics; Alzheimer’ s disease; Parkinson’ s disease; imaging; neurotransmitters; neurodegeneration; clinical; population genetics

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Liver Disease: Etiology, Pathology, and Treatment

edited by Ivana Mikolašević

submission deadline 31 May 2025 | Viewed by 243 | Submission Open

Keywords: chronic liver disease; metabolic-associated fatty liver disease; liver fibrosis; liver injury; etiology; pathology; molecular and cellular mechanisms; biomarkers and therapeutic targets; immunotherapy; prevention and treatment

(This special issue belongs to the Section Cell Biology and Pathology)

Brain Injury: New Insights into Mechanisms and Future Promising Treatments—Second Edition

edited by

Kristina Pilipović

and

Petra Dolenec

submission deadline 31 May 2025 | Viewed by 231 | Submission Open

Keywords: acquired brain injury; nanomedicine; nanotechnology; neuroregenerative therapy; neurorepair; new and emerging treatments; pharmacotherapy; stroke; tissue engineering; traumatic brain injury

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Neuromuscular Diseases: From Pathophysiology to Novel Therapeutic Approaches

edited by Marco A.F. Fernandes

submission deadline 31 May 2025 | Viewed by 225 | Submission Open

Keywords: neuromuscular diseases; amyotrophic lateral sclerosis (ALS); muscular dystrophy; myasthenia gravis; neuromyotonia; peripheral neuropathy; pathophysiology; gene therapy; targeted drugs; regenerative medicine

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Advancements and Challenges in Anticancer Targeted Therapy with Small Molecules

edited by Monika Papiez

submission deadline 31 May 2025 | Viewed by 220 | Submission Open

Keywords: small molecules; cancer; anticancer targeted therapy; cancer resistance; cancer growth blockers

(This special issue belongs to the Section Cancer Biology and Oncology)

Fetal Medicine: New Insights and Future Direction

edited by

Mateusz Zamłyński

submission deadline 31 May 2025 | Viewed by 201 | Submission Open

Keywords: fetal medicine; fetal therapy; prenatal screening; congenital defects; high-risk pregnancy

(This special issue belongs to the Section Molecular and Translational Medicine)

Polyamines in Human Diseases

edited by

Kuniyasu Soda

submission deadline 31 May 2025 | Viewed by 200 | Submission Open

Keywords: polyamine; spermidine; spermine; health; disease; development

(This special issue belongs to the Section Immunology and Immunotherapy)

Feature Reviews in Cancer Genetics and Epigenetics

edited by

Zheng-Yuan Su

submission deadline 31 May 2025 | Viewed by 196 | Submission Open

Keywords: cancer genetics; epigenetics; DNA methylation; histone modifications; non-coding RNAs; tumor heterogeneity; drug resistance; biomarkers; precision oncology; personalized therapy

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

New Advances in Epilepsy Research

edited by Duyu A. Nie

submission deadline 31 May 2025 | Viewed by 190 | Submission Open

Keywords: disease mechanisms; genetics; biomarkers; epilepsy surgery; electroencephalogram; animal models; artificial intelligence

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Biological Therapies for Asthma: Targeting Type 1 and Type 2 Inflammation

edited by Mohammad Irshad Reza and Nilesh Sudhakar Ambhore

submission deadline 31 May 2025 | Viewed by 188 | Submission Open

Keywords: asthma endotypes; type 1 inflammation; type 2 inflammation; biological therapies for asthma; non-type 2 asthma; cytokine pathways in asthma; precision medicine in asthma; inflammatory biomarkers in asthma; Th1/Th2 immune responses

(This special issue belongs to the Section Molecular and Translational Medicine)

Novel Biomarker and Treatments for Diabetic Neuropathy

edited by Arun V. Krishnan and Tushar Issar

submission deadline 31 May 2025 | Viewed by 185 | Submission Open

Keywords: diabetic peripheral neuropathy; type 1 diabetes; type 2 diabetes; glucagon-like peptide-1 receptor agonists; metabolic syndrome; in vivo corneal confocal microscopy; nerve ultrasonography; obesity; exercise

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Ophthalmic Genetics: Unraveling the Genomics of Eye Disorders

edited by Raffaella Cascella

submission deadline 31 May 2025 | Viewed by 182 | Submission Open

Keywords: ophthalmic genetics; inherited retinal disease; genomics; molecular biology; gene therapy; artificial intelligence; bioinformatics; biostatistical analysis

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

New Imaging Strategies for Organoids

edited by

Wolfgang J. Weninger

and

Stefan H. Geyer

submission deadline 31 May 2025 | Viewed by 169 | Submission Open

Keywords: imaging; organoids; 3D imaging; volumetry; characterisation

(This special issue belongs to the Section Molecular and Translational Medicine)

Neurovascular Dysfunction: Mechanisms and Therapeutic Strategies

edited by

Deepti Diwan

submission deadline 31 May 2025 | Viewed by 162 | Submission Open

Keywords: neurovascular; blood vessels; nervous system; neurological diseases

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

From Pathophysiology to Novel Therapeutic Approaches in Alzheimer’s Disease

edited by

Lorenzo Falsetti

submission deadline 31 May 2025 | Viewed by 151 | Submission Open

Keywords: Alzheimer's disease; neurodegeneration; cognitive deterioration; dementia

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Zebrafish Models for Development and Disease—5th Edition

edited by

James A. Marrs

submission deadline 31 May 2025 | Viewed by 149 | Submission Open

Keywords: disease model; drug screening model; teratogen screening; toxicological screening; neuroscience; behavior; developmental biology

(This special issue belongs to the Section Molecular and Translational Medicine)

Parkinson’s Disease: Where Are We and Where Are We Going To

edited by Carmen Borrué

submission deadline 31 May 2025 | Viewed by 140 | Submission Open

Keywords: Parkinson’ s disease; gait disorders; biomarkers; neurodegenerative disease; AI

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Advanced Research in Chronic Respiratory Diseases (CRDs)

edited by

Hung-Yu Huang

submission deadline 31 May 2025 | Viewed by 140 | Submission Open

Keywords: chronic respiratory failure; occupational lung diseases; obstructive pulmonary disease (COPD); asthma; bronchiectasis; interstitial lung disease; cystic fibrosis and lung fibrosis; lung distraction; pneumoconiosis; lung microbiota; smoking

(This special issue belongs to the Section Cell Biology and Pathology)

Molecular Regulation of Cancer Progression and Metastasis to Identify Novel Treatment Strategies

edited by

Vrushank Bhatt

submission deadline 31 May 2025 | Viewed by 139 | Submission Open

Keywords: cancer; cancer progression; cancer treatment; solid tumors; immune response; metastasis; tumor suppressor; oncogene

(This special issue belongs to the Section Cancer Biology and Oncology)

Exercise-Induced Physiological Responses: From Oxidative Stress to DNA Alterations

edited by

Robert Stawski

submission deadline 31 May 2025 | Viewed by 113 | Submission Open

Keywords: exercise-induced oxidative stress; reactive oxygen species (ROS); molecular adaptations to exercise; epigenetic modifications in exercise; DNA damage and repair; cell-free DNA; extracellular DNA; inflammation and exercise; DNA alterations

(This special issue belongs to the Section Cell Biology and Pathology)

Advances of Autophagy in Human Cancers and Tumors

edited by Po-Hsiang Liao

submission deadline 31 May 2025 | Viewed by 96 | Submission Open

Keywords: autophagy; chemoresistance; chaperone-mediated autophagy (CMA); clockophagy; ferritinophagy

(This special issue belongs to the Section Cancer Biology and Oncology)

Application of New Technologies in Drug Delivery

edited by Venkata Raman Kallakunta

submission deadline 31 May 2025 | Viewed by 87 | Submission Open

Keywords: drug delivery; new technologies; nanoparticles; self-emulsifying drug delivery systems (SEDDSs); hot melt extrusion (HME); gene editing; 3D printing

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Spinal Muscular Atrophy: Pathogenesis, Diagnosis, Therapeutics and Future Directions

edited by

Dinko Vitezić

Andrej Belančić

and Valentino Rački

submission deadline 1 Jun 2025 | Viewed by 237 | Submission Open

Keywords: genetic diseases; neuromuscular disorders; rare diseases; spinal muscular atrophy; survival motor neuron protein

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Peptides and Amino Acids in Drug Development: Here and Now

edited by

Siva Panda

submission deadline 6 Jun 2025 | 5 articles | Viewed by 11045 | Submission Open

Keywords: peptide chemistry; amino acids; drug conjugates; drug development; drug delivery; coupling reagents; peptidomimetics; cyclic peptides; peptide ligation

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Antioxidant and Antimicrobial Potencies of Biomolecule

edited by

Vinit Raj

submission deadline 11 Jun 2025 | 3 articles | Viewed by 8907 | Submission Open

Keywords: biomolecules; metabolomics; oxidative stress levels; polymer; microorganisms; nanotechnology

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Molecular Research and Recent Advances in Diabetic Retinopathy: Second Edition

edited by

Tomislav Bulum

and

Martina Tomić

submission deadline 15 Jun 2025 | 7 articles | Viewed by 7816 | Submission Open

Keywords: diabetes; diabetic retinopathy; complications; vascular endothelial growth factor; retina; biomarkers

(This special issue belongs to the Section Cell Biology and Pathology)

Neurodegenerative Diseases: Recent Advances and Future Perspectives, 2nd Edition

edited by

Inés López-Cuenca

and

Rosa De Hoz

submission deadline 25 Jun 2025 | Viewed by 371 | Submission Open

Keywords: neurodegeneration; neuroprotection; dementia; Parkinson’ s disease

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Research Trends in Cardiovascular Pathologies: From Mechanisms to Therapies

edited by

Yang Zhao

, Jifeng Zhang and Chao Xue

submission deadline 30 Jun 2025 | 13 articles | Viewed by 21265 | Submission Open

Keywords: cardiovascular pathology; coronary artery disease; cardiac arrhythmia; heart failure; hypertension; aneurysm; atherosclerosis

(This special issue belongs to the Section Molecular and Translational Medicine)

Wound Healing: From Basic to Clinical Research

edited by

Julian-Dario Rembe

submission deadline 30 Jun 2025 | 15 articles | Viewed by 15961 | Submission Open

Keywords: wound healing; clinical research in wound healing; in vitro experiments in wound healing; in vivo experiments in wound healing; cytokines in wound healing; chronic wounds; pressure sores/ulcers; scar formation

(This special issue belongs to the Section Molecular and Translational Medicine)

Emerging Trends in Dental Caries: Insights into Etiology, Risk Factors, and Treatment Strategies

edited by

Hee-Eun Kim

submission deadline 30 Jun 2025 | 7 articles | Viewed by 11099 | Submission Open

Keywords: antimicrobial effect; demineralization; dental caries; dental plaque; oral biofilm; oral disease; oral management; pathogenicity; prevention; remineralization

(This special issue belongs to the Section Microbiology in Human Health and Disease)

High-Sensitivity Lateral Flow Assays for SARS-CoV-2 and Other Infections, 2nd Edition

edited by

Hideya Kawasaki

submission deadline 30 Jun 2025 | 3 articles | Viewed by 10726 | Submission Open

Keywords: lateral flow assay; point-of-care testing; SARS-CoV-2; high sensitivity; detection device; labeling reporters; antigens; pathogens

(This special issue belongs to the Section Molecular and Translational Medicine)

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