Pathology, Complications and Prognosis of Type 1 Diabetes
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Endocrinology and Metabolism Research".
Deadline for manuscript submissions: 27 February 2026 | Viewed by 25
Special Issue Editor
Special Issue Information
Dear Colleagues,
This Special Issue, Pathology, Complications and Prognosis of Type 1 Diabetes, offers a comprehensive and up-to-date synthesis of current knowledge on the complex pathophysiology and clinical evolution of type 1 diabetes mellitus (T1DM), an autoimmune condition resulting in the progressive destruction of pancreatic β-cells.
The contributions gathered in this issue address the key mechanisms involved in disease initiation and progression, including genetic susceptibility, environmental factors, and immune-mediated processes. A particular focus is placed on the spectrum of complications—both acute, such as diabetic ketoacidosis, and chronic, including microvascular (retinopathy, nephropathy, neuropathy) and macrovascular damage.
The prognostic implications of variables such as age at onset, metabolic control, and disease duration are critically discussed, alongside emerging biomarkers and therapeutic approaches. Integrating clinical experience with advances in translational research, the articles aim to provide a multidimensional understanding of T1DM.
This Special Issue is intended for clinicians, endocrinologists, diabetologists, and researchers, offering evidence-based insights to inform practice and stimulate further investigation into risk reduction and long-term outcome improvement in type 1 diabetes.
Dr. Maurizio Delvecchio
Guest Editor
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Keywords
- type 1 diabetes mellitus
- autoimmune β-cell destruction
- diabetic complications
- microvascular and macrovascular damage
- diabetic ketoacidosis
- glycemic control
- disease prognosis
- immunopathogenesis
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