Diabetes: Comorbidities, Therapeutics and Insights (3rd Edition)

Dear Colleagues,

Diabetes, one of the most challenging health problems of the 21st century, is projected to affect 700 million people by 2045. In the last 15 years, the number of people diagnosed with type 1 diabetes has increased by 45%, and the number diagnosed with type 2 diabetes by 95%. The most devastating effects of diabetes are its chronic complications, which confer a high risk of morbidity and mortality and represent an increased cost burden on health systems. Despite the increased awareness of and new therapeutic options for the treatment of diabetes, it is still the leading cause of blindness in working-age adults, kidney failure and dialysis, and nontraumatic lower-limb amputations. People with diabetes have a two- to four-times higher risk of developing cardiovascular disease, which remains the most common cause of death in people with this disease. Diabetes is a heterogenous and complex disease, and in addition to the traditional risk factors, such as hyperglycemia, hypertension, and dyslipidemia, multiple cellular pathways and potential molecular mechanisms are also implicated in diabetes-induced complications.

Considering this context, we welcome submissions to this Special Issue focusing on diabetes it terms of its comorbidities and therapeutics, as well as contributions providing insights into this disease. Improving our knowledge of diabetes will aid in the prevention of chronic complications and cardiovascular disease/death and in optimizing patients’ quality of life.

Dr. Tomislav Bulum
Guest Editor

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