Special Issues

Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Feature Reviews in Infection and Immunity
edited by
submission deadline 30 Jun 2025 | Viewed by 227 | Submission Open
Keywords: emerging pathogens; antimicrobial resistance; vaccine; host-pathogen immune interactions; immunotherapy; antimicrobial drug; immune evasion; innate and adaptive immunity
(This special issue belongs to the Section Immunology and Immunotherapy)
State-of-the-Art Molecular and Translational Medicine in USA submission deadline 30 Jun 2025 | Viewed by 211 | Submission Open
Keywords: diagnostics; therapeutics; prevention; cellular biology; disease mechanisms; precision medicine; biomarker discovery; immunotherapies; bioinformatics
(This special issue belongs to the Section Molecular and Translational Medicine)
Applications and Developments of Metal-Based Drugs
edited by
submission deadline 30 Jun 2025 | Viewed by 208 | Submission Open
Keywords: anticancer; anti-infectious diseases; nuclear medicines; immunotherapeutic; drug delivery; organometallic complexes; metal-based drugs; metallotherapeutic drugs
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Nephrotic Syndrome: Pathomechanism, Diagnostics and Novel Treatment Options—2nd Edition
edited by
submission deadline 30 Jun 2025 | Viewed by 202 | Submission Open
Keywords: focal segmental glomerulosclerosis; genetic kidney disease; minimal change disease; nephrotic syndrome; podocyte
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Cardiac Fibrosis and Inflammation: Molecular Mechanisms and Therapeutic Frontiers
edited by Melis Olcum
submission deadline 30 Jun 2025 | Viewed by 196 | Submission Open
Keywords: cardiac fibrosis; inflammation; epigenetics; cytokines; inflammasomes; extracellular vesicles; genetic factors; cardiomyopathies; extracellular matrix; fibroblast activation; cardiac biomarker; immune cells; chemokines; heart; in vivo models; in vitro models
(This special issue belongs to the Section Molecular and Translational Medicine)
Ovarian Physiology and Reproduction
edited by Atefeh Najafi
submission deadline 30 Jun 2025 | Viewed by 194 | Submission Open
Keywords: ovarian physiology; female fertility; folliculogenesis; oocyte; hormonal regulation; endocrine disruptors; ovarian aging; genetic modifications; environmental factors and female fertility; female reproductive health and disorders
(This special issue belongs to the Section Molecular and Translational Medicine)
Molecular Research in Ocular Pathology submission deadline 30 Jun 2025 | Viewed by 186 | Submission Open
Keywords: molecular pathology; ocular diseases; biomarkers; diabetic retinopathy; glaucoma; age-related macular degeneration; thyroid eye disease; inflammatory pathways; oxidative stress; angiogenesis; neurodegeneration; gene therapy; cell therapy; precision medicine; ocular imaging
(This special issue belongs to the Section Molecular and Translational Medicine)
Role of Glycomics in Health and Diseases
edited by
submission deadline 30 Jun 2025 | Viewed by 172 | Submission Open
Keywords: glycomics; protein chemistry; tumor immunology; biomarker research
(This special issue belongs to the Section Molecular and Translational Medicine)
Neural Organoids: Advancing Our Understanding of the Central and Peripheral Nervous Systems
edited by Birtele Marcella
submission deadline 30 Jun 2025 | Viewed by 160 | Submission Open
Keywords: neural organoids; brain development; tissue engineering; disease modeling; peripheral nervous system; single-cell analysis; neural circuits; bioengineering; stem cells; neurodevelopmental disorders
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Unleashing the Power of Innovative Nanoparticles for Enhanced Radiation Therapy
edited by Fangchao Jiang
submission deadline 30 Jun 2025 | Viewed by 158 | Submission Open
Keywords: nanomedicine; drug delivery; radiation therapy; nanotheranostics; nanoparticles; cancer treatment; biomaterial
(This special issue belongs to the Section Nanomedicine and Nanobiology)
Recent Advances in Chronic Rhinosinusitis and Asthma: 2nd Edition
edited by and Cristiano Caruso
submission deadline 30 Jun 2025 | Viewed by 149 | Submission Open
Keywords: asthma; chronic rhinosinusitis; nasal polyps; severe asthma; type-2 inflammation; phenotypes; endotypes; biologics; epithelial disfunction; remodeling
(This special issue belongs to the Section Molecular and Translational Medicine)
State-of-the-Art Eye Disease Research and Treatment in Japan
edited by
submission deadline 30 Jun 2025 | Viewed by 141 | Submission Open
Keywords: ocular diseases; age-related macular degeneration; diabetic retinopathy; glaucoma; uveitis
(This special issue belongs to the Section Molecular and Translational Medicine)
Feature Reviews in Immunology and Immunotherapy
edited by
submission deadline 30 Jun 2025 | Viewed by 137 | Submission Open
Keywords: immunotherapy; inflammation; immune cells; cancer cells; monoclonal antibodies; therapeutic vaccines; cytokines
(This special issue belongs to the Section Immunology and Immunotherapy)
Osteoarthritis and Associated Pain: Molecular Research and Novel Therapeutic Approaches, 2nd Edition
edited by
submission deadline 30 Jun 2025 | Viewed by 135 | Submission Open
Keywords: osteoarthritis; pain; cartilage degeneration; molecular pain pathway
(This special issue belongs to the Section Molecular and Translational Medicine)
Quantitative Functional Imaging with CT Perfusion: Technical Considerations, Kinetic Modeling, and Applications
edited by Ting-Yim Lee
submission deadline 30 Jun 2025 | Viewed by 133 | Submission Open
Keywords: perfusion imaging; computed tomography; cardiovascular disease
(This special issue belongs to the Section Molecular and Translational Medicine)
Molecular Biomarkers and More Efficient Therapies for Sepsis—2nd Edition
edited by , Chih-Hao Shen, and
submission deadline 30 Jun 2025 | Viewed by 132 | Submission Open
Keywords: sepsis; organ dysfunction; inflammatory process; molecular biomarkers; pathogen infection; signal transduction mechanisms
(This special issue belongs to the Section Molecular and Translational Medicine)
Emerging Research in Neurorehabilitation, 2nd Edition
edited by
submission deadline 30 Jun 2025 | Viewed by 131 | Submission Open
Keywords: mechanisms; CNS trauma; ischemic CNS injury; neurodegenerative disorders; neurorehabilitation; neuroplasticity; personalized therapy; neuroprosthetics; brain– computer interfaces; neurodevelopmental disorder
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Advances in Fatty Acid Metabolism as the Markers of Civilization Diseases (3rd Edition)
edited by
submission deadline 30 Jun 2025 | Viewed by 125 | Submission Open
Keywords: fatty acids; lipidomics; biochemistry; infalmmation; pathophysiological mechanisms; lipid mediators; gut microbiota; NAFLD/NASH; insulin resistance; type 2 diabetes; endocine diseases; cardiovascular diseases
(This special issue belongs to the Section Molecular and Translational Medicine)
Glioblastoma: From Pathophysiology to Novel Therapeutic Approaches
edited by Ming-Ming Lee
submission deadline 30 Jun 2025 | Viewed by 125 | Submission Open
Keywords: glioblastoma stem cells (GSCs); temozolomide (TMZ); tumor microenvironment; resistance; novel therapeutic approaches
(This special issue belongs to the Section Cancer Biology and Oncology)
Microglia in Neurodegenerative Diseases: Key Mediators of Apoptosis and Inflammatory Pathways
edited by Ana Borrajo
submission deadline 30 Jun 2025 | Viewed by 117 | Submission Open
Keywords: microglia; apoptosis; neurodegenerative diseases; HIV-1; central nervous system
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Recent Advances in Lymphoma: Second Edition submission deadline 30 Jun 2025 | Viewed by 114 | Submission Open
Keywords: lymphoma; cancer; gene expression; mutational analysis; target; therapy; tumor microenvironment
(This special issue belongs to the Section Cancer Biology and Oncology)
Nanoparticle-Based Therapeutic Delivery Systems in Cancer Therapy
edited by
submission deadline 30 Jun 2025 | Viewed by 107 | Submission Open
Keywords: drug delivery; nanomedicine; biomaterials; multimodal drug delivery; tumor microenvironment; immunotherapy; targeted delivery
(This special issue belongs to the Section Cancer Biology and Oncology)
Feature Reviews in Ophthalmology
edited by
submission deadline 30 Jun 2025 | Viewed by 105 | Submission Open
Keywords: glaucoma; retinal diseases; diabetic retinopathy; age-related macular degeneration; retinitis pigmentosa; Leber's congenital amaurosis; ocular surface pathology
(This special issue belongs to the Section Molecular and Translational Medicine)
Exploring Potential Therapeutic Compounds with Anti-Inflammatory Activity
edited by Shomaila Mehmood
submission deadline 30 Jun 2025 | Viewed by 103 | Submission Open
Keywords: green tea polyphenols; isoflavanoids; resveratrol; curcumin; genistein; melatonin; antioxidants; metalloporphyrins; anti-inflammatory compounds
(This special issue belongs to the Section Molecular and Translational Medicine)
Biomarkers, Surrogate Markers and New Therapeutic Insights into Multiple Sclerosis
edited by
submission deadline 30 Jun 2025 | Viewed by 100 | Submission Open
Keywords: marker; surrogate marker; disease-modifying treatment; multiple sclerosis; disease activity; NfLs; CD20; RNFL
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Mitochondrion-Targeting Agents for Tumor Therapy
edited by
submission deadline 30 Jun 2025 | Viewed by 94 | Submission Open
Keywords: mitochondria; cell signaling; apoptosis; cancer therapy
(This special issue belongs to the Section Cancer Biology and Oncology)
Molecular Mechanisms and Therapeutic Advances in Pregnancy-Related Diseases submission deadline 30 Jun 2025 | Viewed by 93 | Submission Open
Keywords: preeclampsia; gestational diabetes; hypertensive disorders of pregnancy; pathogenesis; mechanism; therapy
(This special issue belongs to the Section Molecular and Translational Medicine)
Nanobiomaterials with Antimicrobial and Anticancer Applications: Second Edition
edited by and
submission deadline 30 Jun 2025 | Viewed by 88 | Submission Open
Keywords: nanobiomaterials; nanomaterials biomaterials; anti-bacterial; anti-cancer
(This special issue belongs to the Section Nanomedicine and Nanobiology)
Organisms as Diagnostic Technologies: Harnessing Life for Sensing Mechanisms
edited by and Hideshi Ishii
submission deadline 30 Jun 2025 | Viewed by 74 | Submission Open
Keywords: biological sensors; diagnostic technologies; diagnostic technologies; biological sensing mechanisms; conversion of biological signals; bio-interfaces
(This special issue belongs to the Section Biomedical Engineering and Materials)
Molecular Researches in Pro-Thrombotic Disorders—2nd Edition
edited by
submission deadline 30 Jun 2025 | Viewed by 65 | Submission Open
Keywords: inflammation; thrombosis; hypercoagulable state; coagulation cascade factors; chronic diseases; platelets; platelet activation; endothelial cells; neutrophils; macrophages
(This special issue belongs to the Section Molecular and Translational Medicine)
Applications of Plasma in Cancer Treatment and Physiology
edited by Pradeep Bhartiya
submission deadline 30 Jun 2025 | Viewed by 57 | Submission Open
Keywords: cold atmospheric plasma; non-thermal plasma; reactive species; oxidative stress; cancer therapy; solid tumor; cold plasma and TME
(This special issue belongs to the Section Cancer Biology and Oncology)
Neurodegeneration in Cognitive Impairment and Mood Disorders for Experimental, Clinical, and Translational Neuropsychiatry—Second Edition submission deadline 31 Jul 2025 | 12 articles | Viewed by 29080 | Submission Open
Keywords: Alzheimer’ s disease; Parkinson’ s disease; aging decline; mild cognitive impairment; multiple sclerosis; stroke; psychiatric disorders; depressive disorder; bipolar disorder; post-traumatic stress disorder; anxiety disorder; schizophrenia; somatic symptom disorder; autism spectrum disorder; hyperactive attention deficit disorder; learning disabilities; acquired brain damage; altered cognitive processes; brain functional impairment; neurocognitive disorders; cognitive; behavioral; and functional disorders; acquired trauma; brain plasticity and connectivity; non-invasive brain stimulation; diagnosis and treatment; functional evidence of altered cognition and connectivity
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Gut Microbiota, Diet, and Immunity: Investigating the Connections and Implications for Disease Development: 2nd Edition
edited by
submission deadline 31 Jul 2025 | 18 articles | Viewed by 21659 | Submission Open
Keywords: gut microbiota; diet; immunity; microbiome; dysbiosis; inflammatory bowel diseases; cancer; CVD; T2D; obesity; overweight; autoimmune diseases; metabolic syndromes; immunomodulation; microbial diversity; nutrient– gut microbiota interactions; probiotics; prebiotics; immune system development; disease susceptibility; therapeutic interventions; host– microbe interactions; gut– brain axis; microbial metabolites; precision nutrition
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Exploring Acute Coronary Syndrome: Insights from Basic and Clinical Research
edited by
submission deadline 31 Jul 2025 | 9 articles | Viewed by 20156 | Submission Open
Keywords: acute coronary syndrome; cardiovascular morbidity; myocardial infarction; pathophysiology; diagnostic modalities; therapeutic interventions; translational research
(This special issue belongs to the Section Molecular and Translational Medicine)
Allergic Diseases and Asthma: Molecular Diagnosis and Precision Medicine
edited by
submission deadline 31 Jul 2025 | 6 articles | Viewed by 15042 | Submission Open
Keywords: allergic diseases; molecular diagnostics; precision medicine; biomarkers; diagnostic tools; personalized medicine; omics integration
(This special issue belongs to the Section Immunology and Immunotherapy)
Heart Failure: New Diagnostic and Therapeutic Approaches submission deadline 31 Jul 2025 | 9 articles | Viewed by 11437 | Submission Open
Keywords: heart failure; clinical treatment; basic cardiac research; future perspective; heart failure therapy; cardiotoxicity
(This special issue belongs to the Section Molecular and Translational Medicine)
Advanced in Schizophrenia Research and Treatment
edited by Felix-Martin Werner
submission deadline 31 Jul 2025 | 7 articles | Viewed by 10757 | Submission Open
Keywords: antipsychotic drug; olanzapine; risperidone; schizophrenia; schizoaffective disorder
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Autonomic Dysfunction in Neurological Disorders: Novel Mechanisms and Targets
edited by De-Pei Li and Zixi Cheng
submission deadline 31 Jul 2025 | 4 articles | Viewed by 10366 | Submission Open
Keywords: sympathetic nervous system; parasympathetic nervous system; novel mechanisms; novel molecular; genetic predisposition
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Advanced Research of Gut Microbiota in Health and Diseases—2nd Edition submission deadline 31 Jul 2025 | 6 articles | Viewed by 10246 | Submission Open
Keywords: microbiota; gut; dysbiosis; gut microbiome; pathological conditions; metabolic disorders; autoimmune disease; inflammatory disorders; degenerative diseases
(This special issue belongs to the Section Molecular and Translational Medicine)
Advancements in Understanding and Treating Oral Pathologies: From Dry Mouth to Oral Cancer
edited by Eleni Georgakopoulou and George Laskaris
submission deadline 31 Jul 2025 | 8 articles | Viewed by 10093 | Submission Open
Keywords: oral pathologies; oral diseases; pathogenesis; therapeutic interventions; interdisciplinary nature of oral healthcare; xerostomia; dysgeusia; oral cancer; precancerous lesions; oral inflammatory conditions
(This special issue belongs to the Section Cell Biology and Pathology)
Chronic Pain: From Prevention to Therapeutic Strategies—Second Edition
edited by Isaura Tavares and
submission deadline 31 Jul 2025 | 7 articles | Viewed by 9901 | Submission Open
Keywords: pain pathophysiology; pain prevention; predictive sensory testing; pre- and postoperative chronic pain; new biomarkers in pain; pain management and novel treatments; preemptive analgesia; inflammatory pain
(This special issue belongs to the Section Molecular and Translational Medicine)
Advanced Research in Early Pregnancy Loss and Other Pregnancy Complications
edited by
submission deadline 31 Jul 2025 | 6 articles | Viewed by 9693 | Submission Open
Keywords: pregnancy loss; miscarriage; implantation failure; fetal growth restriction; preeclampsia; fetal death; preterm birth; pathology; pathogenesis; mechanism
(This special issue belongs to the Section Molecular and Translational Medicine)
Cardiac Arrhythmias and Arrhythmogenic Disorders: Technological Frontiers, Drug Development and Future Directions
edited by Siamak Salavatian
submission deadline 31 Jul 2025 | 5 articles | Viewed by 9571 | Submission Open
Keywords: cardiac arrhythmias; arrhythmias diagnostic; arrhythmias therapy; technological frontiers; personalized medicine; biomarkers; neuromodulation; artificial intelligence
(This special issue belongs to the Section Molecular and Translational Medicine)
New Advances in Chronic Kidney Disease: Biology, Diagnosis and Therapy (2nd Edition) submission deadline 31 Jul 2025 | 10 articles | Viewed by 9097 | Submission Open
Keywords: inflammation; kidney biomarkers; kidney injury; chronic kidney disease; dialysis; cardiorenal syndrome risk; CKD anemia; kidney physiopathology; CKD treatment
(This special issue belongs to the Section Cell Biology and Pathology)
Sepsis and Septic Shock: From Molecular Mechanism to Novel Therapies
edited by Fuhong Su
submission deadline 31 Jul 2025 | 5 articles | Viewed by 9088 | Submission Open
Keywords: sepsis; septic shock; molecular mechanisms; specific biomarkers; histone
(This special issue belongs to the Section Cell Biology and Pathology)
New Insights Into Non-Alcoholic Fatty Liver Diseases submission deadline 31 Jul 2025 | 5 articles | Viewed by 8808 | Submission Open
Keywords: NAFLD; non-alcoholic fatty liver disease; metabolic pathways; molecular mechanisms; genetic polymorphisms; population disparities; risk stratification; clinical challenges; nutritional interventions; triglyceride glucose index
(This special issue belongs to the Section Molecular and Translational Medicine)
Recent Advances in Diagnosis and Therapeutic Strategies in Intraocular Inflammation
edited by
submission deadline 31 Jul 2025 | 7 articles | Viewed by 8392 | Submission Open
Keywords: biomarker; diagnosis; immune pharmacology; immune regulation; immune system; infection; uveitis; therapy
(This special issue belongs to the Section Immunology and Immunotherapy)
Oxidative Stress and Inflammation in Non-communicable Diseases submission deadline 31 Jul 2025 | 3 articles | Viewed by 8153 | Submission Open
Keywords: oxidative stress; inflammation; antioxidant therapy; aging; cardiovascular diseases; infertility; metabolic diseases; cancer
(This special issue belongs to the Section Molecular and Translational Medicine)
Molecular Mechanism in Inflammation and Immunity
edited by Anella Saviano
submission deadline 31 Jul 2025 | 3 articles | Viewed by 7869 | Submission Open
Keywords: adaptive immunity; autoimmune-based diseases; cyto/chemokines; inflammation; macrophages; natural compounds; nutraceuticals; signaling pathway in arachidonic acid cascade; T-cells; trained immunity
(This special issue belongs to the Section Cell Biology and Pathology)
3D Cell Culture Systems for Biomedical Research submission deadline 31 Jul 2025 | 6 articles | Viewed by 7674 | Submission Open
Keywords: 3D; scaffolds; spheroids; biomaterials; tumour model; bioengineering; tissue regeneration; regenerative medicine; targeted therapies; tissue mimics; angiogenesis; cancerogenesis; drug development; 3D printing; material functionalisation
(This special issue belongs to the Section Biomedical Engineering and Materials)
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