Special Issues

Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Antimicrobial Stewardship in Solid Organ Transplantation: Optimizing Management of Infections Caused by Resistant Organisms
edited by Abhay Dhand
submission deadline 31 Aug 2025 | Viewed by 244 | Submission Open
Keywords: transplant; antimicrobial stewardship; quality; outcomes; infectious diseases; antimicrobial resistance
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Bleeding Disorders and Dental Implants
edited by
submission deadline 31 Aug 2025 | Viewed by 236 | Submission Open
Keywords: hemostasis; hemophilia; dental implant; oral surgery; anticoagulants
(This special issue belongs to the Section Molecular and Translational Medicine)
The Role of Cytokines in Health and Disease: 3rd Edition
edited by
submission deadline 31 Aug 2025 | Viewed by 221 | Submission Open
Keywords: cytokine; chemokine; neurodegenerative disease; cancer; inflammatory mediator; diagnosis; biomarker
(This special issue belongs to the Section Cell Biology and Pathology)
Emerging Trends in Malignant Mesothelioma
edited by Yuan Xu
submission deadline 31 Aug 2025 | Viewed by 201 | Submission Open
Keywords: mesothelioma; asbestos; novel therapeutic strategies; treatment resistance; multi-omics analysis
(This special issue belongs to the Section Cancer Biology and Oncology)
Genetic Insights and Pharmacogenomic Approaches in Cancer Treatment submission deadline 31 Aug 2025 | Viewed by 172 | Submission Open
Keywords: pharmacogenetics; genetic basis; cancer treatments
(This special issue belongs to the Section Cancer Biology and Oncology)
Epigenetics in the Perioperative Setting
edited by Rump Katharina
submission deadline 31 Aug 2025 | Viewed by 166 | Submission Open
Keywords: epigenetics; perioperative setting; surgical stress; anesthesia; gene expression; cognitive impairment; postoperative delirium; postoperative cognitive dysfunction (POCD); neuroinflammation; therapeutic approaches
(This special issue belongs to the Section Immunology and Immunotherapy)
Head and Neck Cancer: From Mechanisms to Therapeutic Approaches—Advances and Challenges submission deadline 31 Aug 2025 | Viewed by 164 | Submission Open
Keywords: head and neck cancers; target therapy; biomarkers; molecular targets; translational research; pathogenesis; prognosis; diagnostic tool
(This special issue belongs to the Section Cancer Biology and Oncology)
Feature Reviews in Gastrointestinal and Liver Diseases
edited by
submission deadline 31 Aug 2025 | Viewed by 147 | Submission Open
Keywords: gastrointestinal diseases; gut– brain interaction; gut microbiota; inflammatory bowel disease; liver disorders; Crohn’ s disease; cancer; fatty liver disease; malnutrition
(This special issue belongs to the Section Molecular and Translational Medicine)
Pathogenesis and Treatment of Ophthalmic Diseases
edited by
submission deadline 31 Aug 2025 | Viewed by 146 | Submission Open
Keywords: ophthalmology; AI; ocular; eye diseases; retina; cornea; glaucoma; neuro-ophthalmology
(This special issue belongs to the Section Molecular and Translational Medicine)
Epigenetics and Immune Perspectives in Cancer: Overcoming Therapy Resistance
edited by
submission deadline 31 Aug 2025 | Viewed by 132 | Submission Open
Keywords: epigenetics; immunotherapy; therapy resistance; tumor microenvironment; DNA methylation; histone modifications; dietary intervention; non-coding RNAs; immune evasion; combination therapy
(This special issue belongs to the Section Cancer Biology and Oncology)
Central Role of Mitochondrial Oxidative Stress in the Pathophysiology of Disorders (2nd Edition)
edited by and André Quincozes-Santos
submission deadline 31 Aug 2025 | Viewed by 125 | Submission Open
Keywords: mitochondrial dysfunction; reactive oxygen species; bioenergetics; mitochondrial quality control; pathologies; protective agents
(This special issue belongs to the Section Molecular and Translational Medicine)
Obesity and Obesity-Related Pathology
edited by
submission deadline 31 Aug 2025 | Viewed by 119 | Submission Open
Keywords: obesity; obesity-related cardiovascular diseases; obesity-related chronic kidney diseases; diabetes mellitus; depression; obesity-related cancer; adipose tissue; adipocytes; cancer-associated adipocytes; obesity therapies
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Neurodegenerative Diseases: From Mechanisms to Therapeutic Approaches, 2nd Edition submission deadline 31 Aug 2025 | Viewed by 119 | Submission Open
Keywords: neurodegenerative diseases; neurons; mechanism
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Tumor Biomarkers in Gynecology—2nd Edition submission deadline 31 Aug 2025 | Viewed by 104 | Submission Open
Keywords: gynecological cancers; precision medicine; biomarkers
(This special issue belongs to the Section Cancer Biology and Oncology)
Exploring Conventional and Alternative Animal Models in Biomedical Research (Biomedicines) submission deadline 31 Aug 2025 | Viewed by 101 | Submission Open
Keywords: disease modelling; drug discovery and delivery; toxicology; personalized medicine; bioengineering; computational biology; ethical considerations; translational research
(This special issue belongs to the Section Molecular and Translational Medicine)
Nanoparticle-Labeled Exosomes as Theranostic Agents
edited by Karrer M. Alghazali
submission deadline 31 Aug 2025 | Viewed by 101 | Submission Open
Keywords: exosomes; nanotheranostic agent; nanoparticles; exosome labeling; photothermal therapy; drug delivery vehicle; imaging probe
(This special issue belongs to the Section Cell Biology and Pathology)
Cutting-Edge Research on Cardiovascular Nuclear Medicine
edited by Pipitsa N. Valsamaki
submission deadline 31 Aug 2025 | Viewed by 94 | Submission Open
Keywords: transthyretin cardiac amyloidosis; molecular mechanisms; nuclear medicine imaging (SPECT; SPECT/CT; PET/CT); treatment advancements
(This special issue belongs to the Section Molecular and Translational Medicine)
Pathogenesis, Diagnosis and Treatment of Cardiomyopathy and Cardiac Arrhythmias
edited by Sung Il Im
submission deadline 30 Sep 2025 | 6 articles | Viewed by 13667 | Submission Open
Keywords: arrhythmia; cardiomyopathy; pathogenesis; diagnosis
(This special issue belongs to the Section Molecular and Translational Medicine)
State-of-the-Art Drug Discovery and Development in Poland (2nd Edition) submission deadline 30 Sep 2025 | 8 articles | Viewed by 11405 | Submission Open
Keywords: in silico drug target profiling; drug delivery systems; drug– drug interactions; target-based screening; phenotypic screening; pharmaceutical modeling; computational chemistry; targeted therapy; biomarkers; bioimaging
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Neurodevelopmental Disorders: From Pathophysiology to Novel Therapeutic Approaches—2nd Edition
edited by Nader Perroud and Markus Mathaus Kosel
submission deadline 30 Sep 2025 | 4 articles | Viewed by 7697 | Submission Open
Keywords: intellectual disability; autism spectrum disorder; attention-deficit/hyperactivity disorder; drug treatment; neuroimaging
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Pathogenesis, Diagnosis and Treatment of Hematologic Malignancies
edited by
submission deadline 30 Sep 2025 | 7 articles | Viewed by 6586 | Submission Open
Keywords: hematologic malignancies; pathogenesis; diagnosis; treatment; targeted therapy; molecular research
(This special issue belongs to the Section Molecular and Translational Medicine)
Ubiquitylation and Deubiquitylation in Health and Diseases
edited by Tadashi Nakagawa
submission deadline 30 Sep 2025 | 5 articles | Viewed by 6527 | Submission Open
Keywords: ubiquitin ligase; deubiquitinase; health; disease; therapeutics; eukaryotic cells
(This special issue belongs to the Section Molecular and Translational Medicine)
Multidisciplinary Management of Rare Head and Neck Tumors: The Importance of Knowing and Dealing with Them
edited by
submission deadline 30 Sep 2025 | 3 articles | Viewed by 5850 | Submission Open
Keywords: rare head and neck cancers; translational research; therapeutic targets
(This special issue belongs to the Section Cancer Biology and Oncology)
Advanced Research in Cardiovascular and Hemodynamic Monitoring
edited by and Scott T. Benken
submission deadline 30 Sep 2025 | 4 articles | Viewed by 5570 | Submission Open
Keywords: vasopressors; hemodynamic monitoring; hypotension; shock; cardiac arrest; heart rate; blood pressure; critical care; intensive care unit
(This special issue belongs to the Section Molecular and Translational Medicine)
Cardiovascular Diseases in the Era of Precision Medicine submission deadline 30 Sep 2025 | 5 articles | Viewed by 5385 | Submission Open
Keywords: cardiology; precision medicine; cardiovascular diseases; genomics; proteomics; multi-omics; personalized therapy; diagnostic tools; imaging technologies; biosignals
(This special issue belongs to the Section Molecular and Translational Medicine)
Epigenetics and Metabolic Disorders
edited by Patrik Krumpolec
submission deadline 30 Sep 2025 | 1 articles | Viewed by 5281 | Submission Open
Keywords: metabolic diseases; epigenetics; DNA methylation; histone modification; non-coding RNA (ncRNA)-mediated gene regulation; heredity; environmental factors
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Molecular Characteristics of Cerebral Ischemia and Their Therapeutic Applications
edited by E-Jian Lee and Shengyang Huang
submission deadline 30 Sep 2025 | 3 articles | Viewed by 5217 | Submission Open
Keywords: cerebral ischemia; molecular mechanisms; pathophysiology; biomarkers; therapeutic strategies; neuroprotection; ischemic stroke; neuro-inflammation; translational research; neuroplasticity; neurophysiology; neuroscience; neuroelectrophysiology
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Advancements in Lung Cancer Precision Oncology Research and Treatments
edited by , and Francesca Colonese
submission deadline 30 Sep 2025 | 5 articles | Viewed by 5097 | Submission Open
Keywords: lung; cancer; NSCLC; targeted therapies; immunotherapy; precision oncology; EGFR; KRAS; ALK; ROS1
(This special issue belongs to the Section Cancer Biology and Oncology)
Molecular Mechanisms and Treatment of Rheumatic Diseases
edited by Ruxandra Ionescu and
submission deadline 30 Sep 2025 | 2 articles | Viewed by 5046 | Submission Open
Keywords: rheumatology; immune-mediated rheumatic diseases; biologics; DMARDs; arthritis; lupus; vasculitis; spondyloarthritis; targets
(This special issue belongs to the Section Molecular and Translational Medicine)
The Role of NK Cells in Cancer Immunotherapy: Mechanisms, Evasion Strategies, and Therapeutic Advances
edited by Maria Eugenia Garcia Rubino
submission deadline 30 Sep 2025 | 1 articles | Viewed by 4643 | Submission Open
Keywords: NK cells; cancer immunotherapy; tumor evasion; cytotoxicity; CAR-NK; cytokines; IL-2; immunotherapy; tumor microenvironment
(This special issue belongs to the Section Cancer Biology and Oncology)
Advances in Angiogenesis, Inflammation, and Oxidative Stress in Inflammatory Bowel Diseases
edited by and Dan Ionuț Gheonea
submission deadline 30 Sep 2025 | 3 articles | Viewed by 4519 | Submission Open
Keywords: inflammatory bowel disease; angiogenesis; inflammation; oxidative stress
(This special issue belongs to the Section Molecular and Translational Medicine)
An Update on Transplantation Immunology
edited by Hui-Yun Cheng
submission deadline 30 Sep 2025 | 4 articles | Viewed by 4420 | Submission Open
Keywords: transplantation; immunology; immunosuppression; immunomodulation
(This special issue belongs to the Section Immunology and Immunotherapy)
Pharmaceutical Treatments for Typical CKD Comorbidities submission deadline 30 Sep 2025 | 3 articles | Viewed by 4066 | Submission Open
Keywords: natural bioactive compounds; adjuvant treatment; protein energy wasting; mineral bone disorders; metabolic acidosis; hyperhomocysteinemia; uremic sarcopenia; PLADO diet; anemia in CKD
(This special issue belongs to the Section Molecular and Translational Medicine)
State-of-the-Art Hepatic and Gastrointestinal Diseases in Germany
edited by
submission deadline 30 Sep 2025 | 4 articles | Viewed by 3904 | Submission Open
Keywords: biomarker; prevalence; Germany; inflammatory bowel disease; cancer
(This special issue belongs to the Section Molecular and Translational Medicine)
Retinal Vascular Disorders: New Insights into Pathogenesis, Diagnosis and Treatment
edited by Irini P. Chatziralli
submission deadline 30 Sep 2025 | 2 articles | Viewed by 3830 | Submission Open
Keywords: diabetic retinopathy; retinal vein occlusion; retinal artery occlusion; sickle-cell retinopathy; optical coherence tomography; widefield imaging; OCT angiography
(This special issue belongs to the Section Molecular and Translational Medicine)
Latest Research in Post-COVID (Long COVID): Pathological and Treatment Studies of Sequelae and Complications—3rd Edition submission deadline 30 Sep 2025 | 5 articles | Viewed by 3653 | Submission Open
Keywords: COVID-19; long  COVID; pain; function; fatigue; dyspnoea; vaccine
(This special issue belongs to the Section Molecular and Translational Medicine)
Pollutants and Human Health: Focus on Molecular-Level Research submission deadline 30 Sep 2025 | 1 articles | Viewed by 3411 | Submission Open
Keywords: environmental exposure; emerging pollutants; human and ecosystem health; environmental risk assessment; adverse outcome pathways; human risk assessment; endocrine-disrupting chemicals; cardiovascular endocrinology; neurovascular endocrinology; reproductive toxicology
(This special issue belongs to the Section Molecular and Translational Medicine)
Synaptic Function and Modulation in Health and Disease
edited by Jean-Marie C. Bouteiller
submission deadline 30 Sep 2025 | 3 articles | Viewed by 3361 | Submission Open
Keywords: synaptic function; synaptic plasticity; neurotransmitter release; receptor dynamics
(This special issue belongs to the Section Molecular and Translational Medicine)
Pathogenesis, Diagnosis and Treatment of Cardiomyopathy and Cardiac Arrhythmias (2nd Edition)
edited by Sung Il Im
submission deadline 30 Sep 2025 | 5 articles | Viewed by 3012 | Submission Open
Keywords: arrhythmia; cardiomyopathy; pathogenesis; diagnosis
(This special issue belongs to the Section Molecular and Translational Medicine)
Immunometabolic Determinants of Gut–Liver Axis Health submission deadline 30 Sep 2025 | 1 articles | Viewed by 2603 | Submission Open
Keywords: gut microbiota; 'entero-hepatic' axis; gut– liver axis; immunometabolism
(This special issue belongs to the Section Immunology and Immunotherapy)
The Treatment of Cardiovascular Diseases in the Critically Ill submission deadline 30 Sep 2025 | 3 articles | Viewed by 2531 | Submission Open
Keywords: septic cardiomyopathy; takotsubo syndrome; cardiac arrhythmias; acute coronary syndromes; antiplatelets; antithrombotics
(This special issue belongs to the Section Molecular and Translational Medicine)
Advancements in Neuroscience: A Special Issue in Honour of Ramón Y Cajal
edited by
submission deadline 30 Sep 2025 | 1 articles | Viewed by 2462 | Submission Open
Keywords: neurobiology; neuroscience; histology; imaging; nervous system; brain; neurodegenerative diseases; neurodevelopmental disorders; molecular biology; big data mining
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Organoid, Organ-on-Chip and Advanced 2D/3D Models for Human Tissue Engineering Applications
edited by
submission deadline 30 Sep 2025 | 2 articles | Viewed by 2407 | Submission Open
Keywords: organoid; organ-on-chip; 2D/3D model; tissue engineering; induced pluripotent stem cells; in vitro model
(This special issue belongs to the Section Biomedical Engineering and Materials)
Feature Reviews in Biomaterials for Oral Diseases
edited by
submission deadline 30 Sep 2025 | 2 articles | Viewed by 2173 | Submission Open
Keywords: dental composites; ceramics; zirconia; polymers; polyaryletherketone; polyoxymethylene; titanium; bone graft materials; implants
(This special issue belongs to the Section Biomedical Engineering and Materials)
Exploring Protein-Ligand Interaction: Key Insights for Drug Discovery submission deadline 30 Sep 2025 | 1 articles | Viewed by 2163 | Submission Open
Keywords: protein; ligand; bio(macro)molecule; drug; interaction; binding; spectroscopy; calorimetry; molecular docking; molecular dynamics simulation
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
The Art of ART (Assisted Reproductive Technologies) submission deadline 30 Sep 2025 | 3 articles | Viewed by 1378 | Submission Open
Keywords: assisted reproductive technologies; infertility diagnosis; intrauterine insemination (IUI); intracytoplasmic sperm injection (ICSI); in vitro fertilization (IVF); embryo implantation; oocyte quality; preimplantation genetic testing; mitochondrial replacement therapy; follicular recruitment; reproductive medicine
(This special issue belongs to the Section Molecular and Translational Medicine)
Molecular Regulation of Spermatozoa—Second Edition
edited by
submission deadline 30 Sep 2025 | 1 articles | Viewed by 1350 | Submission Open
Keywords: spermatogenesis; spermiogenesis; sperm; capacitation; acrosome reaction; hyperactivation; fertilization; male infertility; antioxidants; redox regulation
(This special issue belongs to the Section Cell Biology and Pathology)
Vascular Pathologies in the Omics Era
edited by
submission deadline 30 Sep 2025 | 1 articles | Viewed by 1274 | Submission Open
Keywords: vascular pathology; blood vessels; omics era; epigenetics; genomics; transcriptomics; proteomics; metabolomics
(This special issue belongs to the Section Cell Biology and Pathology)
Next-Generation Nanoparticles: Innovations in Biomedical Applications and Theranostics
edited by
submission deadline 30 Sep 2025 | 1 articles | Viewed by 1188 | Submission Open
Keywords: nanoparticles; nanoconjugates; antimicrobial agents; anticancer agents; biomedical applications
(This special issue belongs to the Section Nanomedicine and Nanobiology)
Mechanomedicine: Exploring Mechanobiology at the Intersection of Engineering and Biology
edited by
submission deadline 30 Sep 2025 | 1 articles | Viewed by 1156 | Submission Open
Keywords: mechanomedicine; mechanobiology; microphysiological systems; bioengineering; forces
(This special issue belongs to the Section Biomedical Engineering and Materials)
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