Molecular Research in Ocular Pathology

Dear Colleagues,

This Special Issue focuses on the molecular mechanisms underlying ocular diseases and their clinical implications. The aim is to bridge the gap between basic molecular research and clinical applications, providing insights into how molecular pathways influence ocular pathophysiology and how they can be targeted for diagnostic, prognostic, and therapeutic strategies.

Ocular diseases, including diabetic retinopathy, glaucoma, age-related macular degeneration, thyroid eye disease, uveitis, and corneal dystrophies, often involve complex molecular alterations. These changes involve inflammatory cascades, oxidative stress, angiogenesis, neurodegeneration, and immune dysregulation, which contribute to disease onset and progression. Advances in molecular techniques, such as transcriptomics, proteomics, and metabolomics, have discovered key pathways and biomarkers, offering opportunities for precision medicine in ophthalmology.

For this Special Issue, we welcome original research, reviews, and clinical studies that explore molecular mechanisms, identify novel biomarkers, and investigate cutting-edge therapies for ocular diseases. Additionally, we welcome articles addressing the application of advanced paraclinical investigations and imaging modalities in the diagnosis and management of ocular diseases. Topics of interest include, but are not limited to, the following:

• Molecular signaling pathways in ocular diseases.
• The role of biomarkers in early diagnosis and disease monitoring.
• Insights into gene therapy, cell therapy, and molecular-targeted treatments.
• The application of imaging technologies in understanding molecular pathology.

This Special Issue seeks to advance the understanding of ocular disease at a molecular level and foster innovative approaches to improving patient outcomes. Researchers and clinicians are encouraged to contribute to this growing field at the intersection of molecular biology and ocular pathology.

Dr. Sorin Lucian Bolintineanu
Dr. Laura Andreea Ghenciu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.