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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Neuroinflammation: From Mechanisms to Therapeutic Approaches

edited by

Yuen Gao

submission deadline 31 Jul 2026 | Viewed by 22 | Submission Open

Keywords: neuroinflammation; molecular mechanism; cell-free stem-cell-based therapy; anti-inflammation

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Advanced Research in Neuroprotection: 2nd Edition

edited by

Christos Bakirtzis

and Evangelia Kesidou

submission deadline 31 Jul 2026 | Viewed by 21 | Submission Open

Keywords: neuroprotection; neurodegeneration; neuroinflammation; axonal loss; neuropharmacology; traumatic brain injury; blood– brain barrier

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Emerging Strategies in Targeted and Smart Drug Delivery

edited by Candace Day

submission deadline 31 Jul 2026 | Viewed by 20 | Submission Open

Keywords: targeted drug delivery; nanoparticles; drug delivery carriers; controlled release; therapeutic agents; drug formulation

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Molecular Research on Diabetic Retinopathy (DR)

edited by

Siyuan Song

submission deadline 31 Jul 2026 | Viewed by 17 | Submission Open

Keywords: diabetic retinopathy; molecular mechanisms; oxidative stress; inflammation; neurovascular unit; anesthesia and perioperative stress; pain and neuroinflammation; retinal organoids; therapeutic targets

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Hepatotoxicity: From Pathology to Novel Therapeutic Approaches (2nd Edition)

edited by

Sanda Win

submission deadline 15 Aug 2026 | 2 articles | Viewed by 5870 | Submission Open

Keywords: cell death; reactive metabolites; oxidative stress; stress signaling; mitochondria; adaptive immunity; HLA associations; hepatotoxicity; drugs; liver injury; adverse drug reaction; drug-induced autoimmune hepatitis; idiosyncratic-drug-induced liver injury; bile acid; drug-induced cholestasis; hepatotoxins; steatosis; fibrosis

(This special issue belongs to the Section Molecular and Translational Medicine)

Multiple Sclerosis: Diagnosis and Treatment—3rd Edition

edited by

Víctor M. Rivera

submission deadline 31 Aug 2026 | 4 articles | Viewed by 11492 | Submission Open

Keywords: multiple sclerosis; pathogenesis; progressive MS; MRI; disease-modifying therapies; demyelinating disorders; cognitive dysfunction; intestinal microbiota

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Molecular Research in Breast Cancer

edited by

Anna De Blasio

and

Daniela Carlisi

submission deadline 31 Aug 2026 | 4 articles | Viewed by 8080 | Submission Open

Keywords: breast cancer; apoptosis; signaling pathways; drug resistance; metastasis; cancer stem cells; microRNA; biomarkers; drug target; tumor metabolism; tumor immunity

(This special issue belongs to the Section Molecular and Translational Medicine)

Advanced Research on Psychiatric Disorders

edited by Wen Zhang

submission deadline 31 Aug 2026 | 2 articles | Viewed by 7332 | Submission Open

Keywords: psychiatric disorders; artificial intelligence; predictive modeling; personalized treatment strategies; animal experiments; risk factors; multimodal approaches

(This special issue belongs to the Section Molecular and Translational Medicine)

Periodontal Disease and Periodontal Tissue Regeneration—Second Edition

edited by

Irina-Georgeta Sufaru

and

Sorina Mihaela Solomon

submission deadline 31 Aug 2026 | 5 articles | Viewed by 6043 | Submission Open

Keywords: periodontal diagnosis; periodontal immunology; periodontal microbiology; periodontal tissue regeneration; tissue engineering

(This special issue belongs to the Section Biomedical Engineering and Materials)

Animal Models for the Study of Cardiovascular Physiology—Second Edition

edited by Sandra Lia Amaral

submission deadline 31 Aug 2026 | 4 articles | Viewed by 4287 | Submission Open

Keywords: hypertension; stroke; myocardium infarction; arterial stiffness; supravalvular aortic stenosis; cardiac remodeling; capillary angiogenesis; exercise training; vascular diseases; non-pharmacological treatment

(This special issue belongs to the Section Cell Biology and Pathology)

Glomerular Disease and Cystic Kidney Disease: From Pathogenesis to Novel Therapeutic Approaches—2nd Edition

edited by Vassilis Filiopoulos and

Chrysanthi Skalioti

submission deadline 31 Aug 2026 | 1 articles | Viewed by 3267 | Submission Open

Keywords: glomerular disease; glomerulonephritis; glomerulopathy; podocytopathies; ciliopathies; cystic kidney disease; polycystic kidney disease; tolvaptan; vasopressin

(This special issue belongs to the Section Molecular and Translational Medicine)

MicroRNAs in Precision Medicine: Regulation, Biomarkers and Novel Therapeutics

edited by Shing Cheng Tan

submission deadline 31 Aug 2026 | 2 articles | Viewed by 1840 | Submission Open

Keywords: MicroRNAs; non-coding RNAs; biomarkers; therapeutic targets; cancer; omics technologies; precision medicine; disease pathogenesis

(This special issue belongs to the Section Molecular and Translational Medicine)

Mechanism of Mesenchymal Stromal Cells and Their Derivatives in Regenerative Medicine

edited by

Jia Xian Law

and

Kok Lun Pang

submission deadline 31 Aug 2026 | 2 articles | Viewed by 1757 | Submission Open

Keywords: mesenchymal stromal cell; regenerative medicine; stem cell; extracellular vesicle; mechanism of action; paracrine factor; secretome; tissue engineering

(This special issue belongs to the Section Biomedical Engineering and Materials)

Advances in Pathogenesis and Treatment of Infectious Diseases

edited by Francesca Gioia

submission deadline 31 Aug 2026 | 1 articles | Viewed by 457 | Submission Open

Keywords: antimicrobial resistance; phage therapy; host– pathogen interactions; molecular diagnostics; immunotherapy

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Molecular Mechanisms of Normal and Malignant Hematopoiesis: 2nd Edition

edited by

Myunggon Ko

submission deadline 31 Aug 2026 | Viewed by 397 | Submission Open

Keywords: hematopoietic stem cells; self-renewal; differentiation; hematological malignancies; molecular mechanisms; genetic factors; epigenetic factors; transcriptional regulation; HSC niche; targeted therapy

(This special issue belongs to the Section Molecular and Translational Medicine)

Advanced Research in Mitochondrial Medicine and Nanomedicine

edited by

Agnieszka Pyrczak-Felczykowska

submission deadline 31 Aug 2026 | Viewed by 284 | Submission Open

Keywords: nanomedicine; nanoparticles; drug delivery; mitochondria; cancer; neurodegenerative disease; metabolism; targeted therapy; mitochondrial function; bioactive compounds

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Feature Review: Advanced Manufacturing, Biomaterials, and Stem Cells for Tissue and Regenerative Engineering

edited by

Roozbeh Ross Salary

submission deadline 31 Aug 2026 | Viewed by 272 | Submission Open

Keywords: advanced manufacturing; biomaterials; tissue engineering; regenerative medicine

(This special issue belongs to the Section Biomedical Engineering and Materials)

Nanostructures in Medicine: State of the Art and Future Challenges

edited by

Agnieszka Maria Kołodziejczyk

and

Boleslaw Karwowski

submission deadline 31 Aug 2026 | Viewed by 69 | Submission Open

Keywords: nanostructures/particles; anticancer and theranostic nanostructures; synthesis methods; disease diagnosis; bioinformatics; DNA damage/repair; clinical trials; drug delivery systems; advanced biomedical applications

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Translational and Precision Medicine in Osteoarthritis, Bone Healing and Musculoskeletal Diseases

edited by

James Vun

Payal Ganguly

and Heather Elizabeth Owston

submission deadline 31 Aug 2026 | Viewed by 63 | Submission Open

Keywords: osteoarthritis; non-union; osteoporosis; fracture related infection; fragility; bone regeneration; mesenchymal stromal cells; tissue engineering; scaffolds; growth factors

(This special issue belongs to the Section Molecular and Translational Medicine)

Innovative Anticancer Agents: Design, Synthesis and Pharmacological Evaluation

edited by

Sreenivasan Sasidharan

submission deadline 31 Aug 2026 | Viewed by 53 | Submission Open

Keywords: anticancer agents; drug design; pharmacological evaluation; structure– activity relationship; molecular docking; apoptosis; phytochemicals; oxidative stress; targeted therapy; natural products

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Oncolytic Viruses and Combinatorial Immunotherapy for Cancer (2nd Edition)

edited by

Zong Sheng Guo

and

Michael H. Lehmann

submission deadline 31 Aug 2026 | Viewed by 41 | Submission Open

Keywords: oncolytic virus; antitumor immunity; cold tumor; tumor antigen; cancer vaccine; immunotherapy; combinatorial therapy; immune checkpoint blockade

(This special issue belongs to the Section Immunology and Immunotherapy)

Horizons in Drug Discovery, Development, and Delivery

edited by

Chun-Wai Mai

submission deadline 31 Aug 2026 | Viewed by 33 | Submission Open

Keywords: drug discovery; drug delivery; nanomedicine; computational pharmacology; targeted therapy; biopharmaceutical formulation; translational medicine; precision medicine; drug development pipeline; nanocarriers

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Insights into Retinal Development, Disease, and Neuroprotection with Pharmacologic and Perioperative Considerations

edited by Siyuan Song

submission deadline 31 Aug 2026 | Viewed by 30 | Submission Open

Keywords: retinal development; retinal degeneration; diabetic retinopathy; glaucoma/optic neuropathy; neuroprotection; neuroinflammation; microglia; single-cell/spatial omics; retinal organoids; anesthesia and analgesia

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Innovative Approaches to Molecular Pathogenesis and Therapy of Lymphoid Malignancies: 2nd Edition

edited by

Sara Elgamal

and

Dalia El-Gamal

submission deadline 31 Aug 2026 | Viewed by 24 | Submission Open

Keywords: lymphoma; leukemia; myeloma; lymphoproliferative disorders; B-cell neoplasms; T-cell neoplasms; pathogenesis; molecular targets; novel therapies; translational research; tumor microenvironment

(This special issue belongs to the Section Cell Biology and Pathology)

Advanced Research on MicroRNAs in Health and Disease

edited by Maram Arafat and

Celestino Sardu

submission deadline 31 Aug 2026 | Viewed by 23 | Submission Open

Keywords: miRNA; cancer; disease; therapy; biomarker

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Fabry Disease: From Molecular Insights to Innovative Therapeutics (2nd Edition)

edited by

Yuri Battaglia

submission deadline 31 Aug 2026 | Viewed by 22 | Submission Open

Keywords: Fabry disease; lysosomal storage disorder; GLA gene mutations; enzyme replacement therapy; chaperone therapy; physical activity; imagining

(This special issue belongs to the Section Molecular and Translational Medicine)

Emerging Therapies, Diagnostic Approaches, and Mechanistic Insights in Allergic Diseases

edited by

Roxana Silvia Bumbãcea

submission deadline 31 Aug 2026 | Viewed by 19 | Submission Open

Keywords: allergic diseases; allergological work-up; component-resolved diagnosis; biomarkers; endotypes and phenotypes; asthma; atopic dermatitis; chronic urticaria; food allergy; drug hypersensitivity; immunotherapy; biologic therapies; precision medicine

(This special issue belongs to the Section Immunology and Immunotherapy)

Trends in 3D Printing Processes for Biomedical Field: Opportunities and Challenges (2nd Edition)

edited by

M. R. Mozafari

submission deadline 15 Sep 2026 | 1 articles | Viewed by 6391 | Submission Open

Keywords: 3D/4D bioprinting techniques; 3D bioprinting processes; 3D cellular microenvironment; bio-inks; hydrogels

(This special issue belongs to the Section Biomedical Engineering and Materials)

Feature Reviews in Biomaterials for Oral Diseases

edited by

Oliver Schierz

submission deadline 30 Sep 2026 | 3 articles | Viewed by 6674 | Submission Open

Keywords: dental composites; ceramics; zirconia; polymers; polyaryletherketone; polyoxymethylene; titanium; bone graft materials; implants

(This special issue belongs to the Section Biomedical Engineering and Materials)

Emerging Trends in Cardioimmunology: Pathomechanisms and Therapeutic Strategies

edited by

Gabriel Adzika

submission deadline 30 Sep 2026 | Viewed by 280 | Submission Open

Keywords: cardiovascular diseases; inflammation; auto-immunity; pathological remodeling; immunomodulation; treatment strategies

(This special issue belongs to the Section Immunology and Immunotherapy)

The Peripheral Nervous System: Morphology and Function

edited by Samanta Taurone

submission deadline 30 Sep 2026 | Viewed by 216 | Submission Open

Keywords: peripheral nerves; plexuses; dismetabolic neuropathies; inflammatory neuropathies; nerve trunk morphology; nerve trunk cells; nerve injury; neurophysiology; nerve repair; PNS regeneration

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Immunometabolism in Disease Development

edited by Aurora Garcia Tejedor and

Jose Moisés Laparra

submission deadline 30 Sep 2026 | Viewed by 92 | Submission Open

Keywords: immunometabolism; metabolic reprogramming; cancer immunometabolism; metabolic checkpoints; therapeutic targeting; chronic inflammation; signaling pathways; gut– liver– brain; bioenergetics

(This special issue belongs to the Section Immunology and Immunotherapy)

Computed Tomography Cardiac Imaging: Challenges, Current Status, and Advances

edited by Ammar Hoori

submission deadline 30 Sep 2026 | Viewed by 66 | Submission Open

Keywords: computed tomography; coronary CT angiography (CCTA); CT calcium scoring (CTCS); FFR-CT; CT perfusion imaging; quantitative imaging biomarkers; image reconstruction; artifact reduction; artificial intelligence; deep learning

(This special issue belongs to the Section Biomedical Engineering and Materials)

Decoding Metabolic Dysfunction: Multi-Omics Biomarkers and Their Modulation by Bioactives

edited by Bojlul Bahar

submission deadline 30 Sep 2026 | Viewed by 21 | Submission Open

Keywords: multi-omics; metabolic dysfunction; nutraceuticals; biomarkers; metabolomics; nutrigenomics; epigenetics; chronic disease; precision nutrition

(This special issue belongs to the Section Molecular and Translational Medicine)

Musculoskeletal Diseases: From Molecular Basis to Therapy—3rd Edition

edited by

Elisa Belluzzi

and

Assunta Pozzuoli

submission deadline 31 Oct 2026 | 7 articles | Viewed by 10136 | Submission Open

Keywords: musculoskeletal diseases; bone cancer; soft tissue cancer; bone metastasis; natural compounds; anticancer drugs; osteoarthritis; joint tissues; biomarkers; inflammation; microRNAs; exosomes

(This special issue belongs to the Section Molecular and Translational Medicine)

Phenotypes and Endotypes in Interstitial Lung Diseases—Second Edition

edited by

Francesco Amati

submission deadline 31 Oct 2026 | 2 articles | Viewed by 1363 | Submission Open

Keywords: interstitial lung diseases (ILDs); heterogeneity; pathogenesis; progressive pulmonary fibrosis (PPF); molecular biomarkers

(This special issue belongs to the Section Immunology and Immunotherapy)

From Gut to Vascular Health: The Role of Probiiotics, Polyphenols, and Diet in Neuroinflammation and Cardiovascular Dysfunction

edited by Maria Serra and

Roberta Macri

submission deadline 31 Oct 2026 | Viewed by 49 | Submission Open

Keywords: nutrition supplements; plant extract; polyphenols; oxidative stress; inflammation; neuroinflammation; microbiota; cardiometabolic dysfunction

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Respiratory Infections: New Diagnostic and Therapeutic Approaches

edited by Aleksandar Sovtic

submission deadline 31 Oct 2026 | Viewed by 45 | Submission Open

Keywords: pneumonia; lower respiratory infections; respiratory microbiota; cystic fibrosis; pneumococcal disease; bronchiolitis; pertussis; biofilm

(This special issue belongs to the Section Molecular and Translational Medicine)

Advanced Research on Genitourinary Cancer

edited by Jue Wang

submission deadline 30 Nov 2026 | 3 articles | Viewed by 9791 | Submission Open

Keywords: genitourinary (GU) cancer; prostate; bladder; kidney; and testicular cancer; diagnosis; treatment; pathogenesis; precision medicine; biomarker discovery; genomic profiling

(This special issue belongs to the Section Molecular and Translational Medicine)

Pediatric Tumors: Diagnosis, Pathogenesis, Treatment, and Outcome

edited by Hermann L. Müller

submission deadline 30 Nov 2026 | 5 articles | Viewed by 5233 | Submission Open

Keywords: pediatric oncology; leukemia; sarcoma; brain tumor; chemotherapy; irradiation; targeted therapy; sequelae

(This special issue belongs to the Section Cancer Biology and Oncology)

From Molecules to Minds: Translational Breakthroughs in Preclinical Psychiatry

edited by

Masaru Tanaka

Simone Battaglia

and

Sandra Barbalho

submission deadline 31 Dec 2026 | 1 articles | Viewed by 4205 | Submission Open

Keywords: depression; anxiety; bipolar disorder; post-traumatic stress disorder; mental disorders; epigenomics; psychiatric disorders/genetics; circadian rhythm; sex characteristics; mitochondrial dysfunction; neurotoxins; intergenerational transmission; cannabinoid receptor modulators; adolescent neuroplasticity; synaptic pruning; psychoimmunology; preclinical studies; translational medical research; neuroplasticity; neuromodulation; phytochemicals; plant extracts; transcranial magnetic stimulation

(This special issue belongs to the Section Molecular and Translational Medicine)

Pathophysiology of Fatty Acid Metabolism

edited by

Nikolina Kolobarić

and

Ines Drenjančević

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2619 | Submission Open

Keywords: fatty acids; signalling molecules; gene expression; metabolic disorders

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Optogenetic Tools for Probing Biology

edited by

Qunxiang Ong

submission deadline 31 Dec 2026 | Viewed by 223 | Submission Open

Keywords: optogenetics; signaling transduction; neuroscience; immunology; cancer signaling; synthetic biology; spatiotemporal resolution

(This special issue belongs to the Section Molecular and Translational Medicine)

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