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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Next-Generation Nanoparticles: Innovations in Biomedical Applications and Theranostics

edited by

Md Amdadul Huq

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1170 | Submission Open

Keywords: nanoparticles; nanoconjugates; antimicrobial agents; anticancer agents; biomedical applications

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Mechanomedicine: Exploring Mechanobiology at the Intersection of Engineering and Biology

edited by

Wenqiang Du

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1155 | Submission Open

Keywords: mechanomedicine; mechanobiology; microphysiological systems; bioengineering; forces

(This special issue belongs to the Section Biomedical Engineering and Materials)

New Horizons in Enzyme Inhibitor Discovery: Targets, Design and Evaluation

edited by Chenzhou Hao, Jing Guo, Yin Sun and Tongchao Liu

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1022 | Submission Open

Keywords: enzyme inhibitors; drug design; inhibitor screening; medicinal chemistry; targets validation; structure– activity relationship; structure– property relationship

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Advanced Research in Thyroid and Parathyroid Diseases

edited by Anping Su

submission deadline 30 Sep 2025 | 2 articles | Viewed by 986 | Submission Open

Keywords: thyroid cancer treatment; tumor microenvironment; immunotherapy; targeted therapy; precision medicine

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances in Therapeutic Strategies and Precision Medicine in Solid Tumors and Metastasis—2nd Edition

edited by

Silvia Di Agostino

and

Vittoria Rago

submission deadline 30 Sep 2025 | 1 articles | Viewed by 813 | Submission Open

Keywords: kinase inhibitor; immunotherapy; chemotherapy; precision molecular therapy; biomarkers; synthetic lethality; theranostics; drug repurposing; radiomics

(This special issue belongs to the Section Cancer Biology and Oncology)

Recent Research on Dry Eye

edited by Liat Gantz

submission deadline 30 Sep 2025 | 1 articles | Viewed by 776 | Submission Open

Keywords: dry eye; meibomian gland dysfunction; ocular surface disease

(This special issue belongs to the Section Molecular and Translational Medicine)

Inherited Retinal Diseases: From Pathomolecular Mechanisms to Therapeutic Strategies, 2nd Edition

edited by

José Martín-Nieto

submission deadline 30 Sep 2025 | 1 articles | Viewed by 769 | Submission Open

Keywords: blindness; gene and protein function; pathogenesis; personalized diagnosis; precision therapy; retina; retinal degeneration

(This special issue belongs to the Section Molecular and Translational Medicine)

Stem Cell Therapy: Traps and Tricks

edited by

Martina Perše

and Željka Večerić-Haler

submission deadline 30 Sep 2025 | 1 articles | Viewed by 642 | Submission Open

Keywords: mesenchymal stem cells; MSC therapy; preclinical research; regenerative medicine

(This special issue belongs to the Section Biomedical Engineering and Materials)

Impacts of Exercise, Nutrition, Obesity, Metabolism and Ageing on Regenerative Medicine and Their Applications in Tissue Engineering and Therapeutics

edited by

Abdelaziz Ghanemi

submission deadline 30 Sep 2025 | 1 articles | Viewed by 622 | Submission Open

Keywords: obesity; exercise; nutrition (diet); obesity; metabolism; ageing; regenerative medicine; tissue engineering; therapeutics

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Molecular and Cellular Research in Diabetes and Metabolic Diseases

edited by Miwon Ahn

submission deadline 30 Sep 2025 | 1 articles | Viewed by 569 | Submission Open

Keywords: insulin exocytosis; pre-diabetes; type 2 diabetes; organ cross-talk; diabetes drugs; diabetes clinical study; glucose homeostasis

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Biomedical Devices—Applications for Disease Treatment and Tissue Regeneration

edited by Eleni Papachristou

submission deadline 30 Sep 2025 | 1 articles | Viewed by 550 | Submission Open

Keywords: biomedical devices; mesenchymal stem cell; biomedical applications; Tissue engineering

(This special issue belongs to the Section Biomedical Engineering and Materials)

Innovative Approaches in Drug Discovery

edited by Jitendra Gour

submission deadline 30 Sep 2025 | Viewed by 547 | Submission Open

Keywords: PROTACs; molecular glue; personalized medicine; high-throughput screening (HTS); targeted therapy; drug repurposing; safety profiles

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Advanced Molecular Mechanisms and Treatment of Neurological Diseases

edited by

Zhouqing Chen

and Yanbo Yang

submission deadline 30 Sep 2025 | 1 articles | Viewed by 508 | Submission Open

Keywords: neurological disease; molecular mechanisms; neuroinflammation; metabolism; biomarkers; neuroprotection; gene therapy; omics; drug discovery; personalized medicine

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Drug-Resistant Bacterial Infections and Alternative Therapies—2nd Edition

edited by

Vijay Singh Gondil

submission deadline 30 Sep 2025 | 1 articles | Viewed by 485 | Submission Open

Keywords: alternative agents; antibiotics; phages; endolysins; phytochemicals; drug discovery; nanoparticles; biofilms

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Medical Imaging in Brain Tumor: Charting the Future

edited by

Subrata Bhattacharjee

and

Mansoor Hayat

submission deadline 30 Sep 2025 | Viewed by 468 | Submission Open

Keywords: brain tumor diagnosis; artificial intelligence (AI) in medical imaging; imaging biomarkers for brain tumor; detection; segmentation and classification; radiomics and radiogenomics; precision oncology; deep learning and machine learning; neuro oncology; digital pathology; treatment response monitoring

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Integrative and Preventive Biomarkers for Cardiometabolic Diseases

edited by Tandi E. Matsha and

Shanel Raghubeer

submission deadline 30 Sep 2025 | Viewed by 458 | Submission Open

Keywords: metabolic health; diabetes; cardiovascular disease; obesity; biomarkers; inflammation; endocrine; integrative medicine; epigenetics

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Stroke Neuroprotection and Repair

edited by

Konstantinos Tsamakis

submission deadline 30 Sep 2025 | 1 articles | Viewed by 440 | Submission Open

Keywords: stroke; cerebral infarction; neuronal damage; neural regeneration; neuroprotection

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

New Advances in Ovarian Cancer

edited by

Zhenshan Yang

submission deadline 30 Sep 2025 | Viewed by 406 | Submission Open

Keywords: ovarian cancer; biomarkers; cell biology; gene regulation; target therapy; therapeutic resistance; precision medicine

(This special issue belongs to the Section Cancer Biology and Oncology)

Advanced Research on the Role of Biogenic Amines in Physiological and Pathological Conditions

edited by

Pellegrino Lippiello

Luisa Speranza

and

Maria Grazia Ferraro

submission deadline 30 Sep 2025 | Viewed by 370 | Submission Open

Keywords: biogenic amines; memory; synapse; depression; anxiety; schizophrenia; glioma and neurodegenerative diseases

(This special issue belongs to the Section Molecular and Translational Medicine)

Eosinophil: Current Status and Future Perspectives

edited by

Ildiko Horvath

submission deadline 30 Sep 2025 | Viewed by 349 | Submission Open

Keywords: eosinophils; predictive biomarker; severe asthma; blood cell count; anti-eosinophils; mortality

(This special issue belongs to the Section Cell Biology and Pathology)

Epigenetic Regulation of Kidney Development

edited by Hongbing Liu

submission deadline 30 Sep 2025 | 1 articles | Viewed by 341 | Submission Open

Keywords: epigenetic regulation; kidney development; gene expression patterns; targeted therapeutic strategies; epigenetic regulation of kidney development

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Innovations and Prospects in Single Cell RNA-seq for Biomedical Research

edited by

Hui-Qi Qu

submission deadline 30 Sep 2025 | Viewed by 335 | Submission Open

Keywords: bioinformatics; cellular heterogeneity; methodology; molecular biology; single-cell RNA sequencing; single-nucleus RNA sequencing; tissue heterogeneity; transcriptomics

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Hearing Loss: Mechanisms and Targeted Interventions

edited by Pavlidis Pavlos

submission deadline 30 Sep 2025 | Viewed by 331 | Submission Open

Keywords: hearing loss; syndromes; anatomy and physiology of the ear; implants; cochlear implantation; diseases of the middle ear; rehabilitation

(This special issue belongs to the Section Cell Biology and Pathology)

Diagnostic and Therapeutic Challenges of CAR-T Cell Therapy

edited by Vincenzo Maria Perriello

submission deadline 30 Sep 2025 | Viewed by 319 | Submission Open

Keywords: CAR-T therapy; immunotherapy; relapsed/refractory diffuse large B cell lymphoma (r/r DLBCL); relapsed/refractory mantle cell lymphoma (r/r MCL); B-acute lymphoblastic leukemia (r/r B-ALL); bridging therapy; cytokine release syndrome (CRS); immune effector cell associated neurotoxicity (ICANS); biomarkers; PET/CT assessment after CAR-T cell therapy

(This special issue belongs to the Section Gene and Cell Therapy)

The Role of the Myofibroblast in Fibrosis and Cancer

edited by Bingrui Li, Xuebin Fu, Xiaodong Zou and Xue Wan

submission deadline 30 Sep 2025 | Viewed by 316 | Submission Open

Keywords: fibroblasts and myofibroblasts; fibrosis (organ and tissue fibrosis); cancer; tissue injury; extracellular matrix

(This special issue belongs to the Section Molecular and Translational Medicine)

Applications of Mass Spectrometry-Based Methods to Explore the Impact of Circadian Rhythms on Disease

edited by Robin Joshi

submission deadline 30 Sep 2025 | Viewed by 286 | Submission Open

Keywords: circadian biology; metabolomics; multiomics; method development; circadian biology; mass spectrometry; proteomics and post-translational modifications in disease; translational medicines; chronopharmacology

(This special issue belongs to the Section Biomedical Engineering and Materials)

New Advances in Neuropharmacology

edited by

Yu-Cheng Ho

and

Ming Tatt Lee

submission deadline 30 Sep 2025 | Viewed by 284 | Submission Open

Keywords: behavioral neuropharmacology; molecular neuropharmacology; neuropharmacology; neurological disorders; neurodegenerative diseases

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Selected Papers in the 3rd International Electronic Conference on Biomedicines (ECB 2025)

edited by

and

submission deadline 30 Sep 2025 | Viewed by 283 | Submission Open

Keywords: insulin resistance or hyperinsulinemia; immunotherapy and adverse effects; tumor microenvironment; immune system; tumor immunology; autoimmune disease; cardiovascular diseases; diabetes; obesity; metabolic diseases; gene therapy; gene editing; cell therapy; rare diseases; neurodegeneration

(This special issue belongs to the Section Molecular and Translational Medicine)

DNA Methylation Profiling for the Classification and Diagnosis of Tumors

edited by

Valeria Barresi

submission deadline 30 Sep 2025 | Viewed by 281 | Submission Open

Keywords: DNA methylation; tumors; central nervous system; soft tissues; haematolymphoid tumors; diagnostic tool

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Advances in Drug Discovery and Development Using Mass Spectrometry

edited by Emily G. Werth,

Amirata Saei Dibavar

and Lin-Zhi Chen

submission deadline 30 Sep 2025 | Viewed by 279 | Submission Open

Keywords: LC/MS; proteomics; protein therapeutics; PTMs; immunocapture; CQAs

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Immunogenetic Regulations for Disease Prognosis

edited by Anshuman Mishra and

Trim Lajqi

submission deadline 30 Sep 2025 | Viewed by 252 | Submission Open

Keywords: immunity; host susceptibility; gene expression; biotechnology; disease resistance; immunogenicity; drug monitoring; vaccines; adaptive immunity

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Medicinal Cannabis: Advances in Therapeutics and Clinical Applications

edited by

Erin Berthold

submission deadline 30 Sep 2025 | Viewed by 207 | Submission Open

Keywords: medicinal cannabis; cannabidiol (CBD); cannabigerol (CBG); cannabinoid; cannabinol (CBN)

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Skin Fibrosis and Cutaneous Wound Healing—2nd Edition

edited by

Noriko Aramaki-Hattori

submission deadline 30 Sep 2025 | Viewed by 199 | Submission Open

Keywords: fibroblasts; inflammation; fibrosis; cutaneous wound healing

(This special issue belongs to the Section Molecular and Translational Medicine)

Urticaria: New Insights into Pathogenesis, Diagnosis and Therapy

edited by

Angela Rizzi

submission deadline 30 Sep 2025 | Viewed by 189 | Submission Open

Keywords: acute urticaria; chronic urticaria; pathogenesis; mast cells; biomarkers; diagnosis; biologicals

(This special issue belongs to the Section Molecular and Translational Medicine)

Neuroscience Through Electrophysiology: Current Trends and Future Directions

edited by

Xiaokuang Ma

submission deadline 30 Sep 2025 | Viewed by 184 | Submission Open

Keywords: electrophysiology; neural circuit; synaptic plasticity; neuronal membrane; patch-clamp; action potential; ion channels; neurodevelopmental disorders; neurodegenerative disorders

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Roles of Extracellular Vesicles in the Complex Interaction Between Metabolic Disorder and Cancer

edited by

Keyang Xu

submission deadline 30 Sep 2025 | Viewed by 184 | Submission Open

Keywords: extracellular vesicles; metabolic disorders; obesity; diabetes; cardiovascular diseases; cancer; mechanism; diagnosis; treatment

(This special issue belongs to the Section Molecular and Translational Medicine)

Prostate Cancer Pathology: Recent Advances and Future Perspectives

edited by

Kostis Gyftopoulos

submission deadline 30 Sep 2025 | Viewed by 168 | Submission Open

Keywords: prostate cancer; pathology; digital pathology; Gleason grading; molecular biomarkers; precision medicine; molecular pathology; molecular profiling; therapy resistance

(This special issue belongs to the Section Cancer Biology and Oncology)

Mycobacterial Infections: Insights into Pathogenesis, Diagnosis, and Treatment

edited by

Abhishek Mishra

submission deadline 30 Sep 2025 | Viewed by 164 | Submission Open

Keywords: mycobacterium; pathogenesis; host– pathogen interactions; virulence factors; antimicrobial resistance; diagnosis; therapeutics; host-directed therapy; vaccine development; drug resistance

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Advances in Oral Squamous Cell Carcinoma Research

edited by Sangang Wu

submission deadline 30 Sep 2025 | Viewed by 151 | Submission Open

Keywords: oral squamous cell carcinoma; diagnostic biomarkers; therapeutic strategies; tumor microenvironment; radiotherapy; single-cell sequencing; artificial intelligence in oncology; personalized medicine; molecular mechanism; recurrence and metastasis

(This special issue belongs to the Section Cancer Biology and Oncology)

Oral Cancer: From Pathophysiology to Novel Therapeutic Approach

edited by

Chan-Yen Kuo

submission deadline 30 Sep 2025 | 1 articles | Viewed by 147 | Submission Open

Keywords: oral cancer and pathophysiology; molecular mechanisms; biomarkers; immunological and targeted therapy; precision medicine and personalized therapies

(This special issue belongs to the Section Molecular and Translational Medicine)

Bone Diseases: Pathophysiology and Molecular Biology

edited by

Tommaso Greco

Carlo Perisano

and Nicola De Gasperis

submission deadline 30 Sep 2025 | Viewed by 145 | Submission Open

Keywords: bone diseases; osteoporosis; osteoarthritis; Paget’ s disease; bone tumors

(This special issue belongs to the Section Molecular and Translational Medicine)

Immune Checkpoint Molecules and Cancer Immunotherapy

edited by Zhiyuan Qin and Shujing Liu

submission deadline 30 Sep 2025 | Viewed by 142 | Submission Open

Keywords: immune checkpoint molecules; cancer immunity; tumor immune microenvironment; cancer immunotherapy; biomarkers

(This special issue belongs to the Section Immunology and Immunotherapy)

Emerging Trends in Cardioimmunology: Pathomechanisms and Therapeutic Strategies

edited by

Gabriel Adzika

submission deadline 30 Sep 2025 | Viewed by 142 | Submission Open

Keywords: cardiovascular diseases; inflammation; auto-immunity; pathological remodeling; immunomodulation; treatment strategies

(This special issue belongs to the Section Immunology and Immunotherapy)

Advanced Research in Metabolic Syndrome (2nd Edition)

edited by

Balazs Varga

submission deadline 30 Sep 2025 | Viewed by 136 | Submission Open

Keywords: obesity; diabetes; dyslipidemia; hypertension; microcirculatory damage; ischemia– reperfusion; necro-apopto-autophagy; laboratory animals; bioactive agents

(This special issue belongs to the Section Cell Biology and Pathology)

New Advances in Gastroenterology and Hepatology: Special Focus on Microvesicles

edited by Fabrizio Pizzolante

submission deadline 30 Sep 2025 | Viewed by 135 | Submission Open

Keywords: cirrhosis; hepatocellular carcinoma; metabolic-associated fatty liver disease; inflammatory bowel disease; liquid biopsy; microvescicals

(This special issue belongs to the Section Cell Biology and Pathology)

State-of-the-Art Dermatology in Spain

edited by

Francisco José Navarro-Triviño

and

Ricardo Ruiz-Villaverde

submission deadline 30 Sep 2025 | Viewed by 133 | Submission Open

Keywords: dermatological research; dermatology; skin disease; psoriasis; atopic dermatitis; urticaria; alopecia areata

(This special issue belongs to the Section Molecular and Translational Medicine)

Lymphomas: From Mechanisms to Therapeutic Approaches

edited by Delfa Radić-Krišto and

Vibor Milunović

submission deadline 30 Sep 2025 | Viewed by 133 | Submission Open

Keywords: aggressive lymphomas; cellular therapy; cellular immunotherapy; translational medicine; lymphomagenesis; indolent lymphomas; phase I/II clinical trials; targeted therapy; biomarkers; in vitro and in vivo models of lymphomas

(This special issue belongs to the Section Cancer Biology and Oncology)

Epilepsy: Pathomechanism, Diagnostics, and Novel Treatment Options

edited by

Monika Rudkowska

and

Karolina Wojtunik-Kulesza

submission deadline 30 Sep 2025 | Viewed by 133 | Submission Open

Keywords: epilepsy; pathophysiology; neurobiology; molecular pathways; experimental models of epilepsy; neuroinflammation; seizure prediction; biomarker discovery; electrophysiological studies; precision neurology

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Advances Research on Nanomedicine

edited by

Rongcheng Han

submission deadline 30 Sep 2025 | Viewed by 132 | Submission Open

Keywords: multifunctional nanomaterials; nanomedicine; tumor; theranostics; artificial intelligence (AI); immunotherapy

(This special issue belongs to the Section Biomedical Engineering and Materials)

Advances in Immunotherapy and Radiation Therapy for Cancer (2nd Edition)

edited by

Ivaylo B. Mihaylov

and Benjamin Spieler

submission deadline 30 Sep 2025 | Viewed by 128 | Submission Open

Keywords: radiotherapy; immunotherapy; outcome; toxicity; normal tissue; abscopal; tumor; systemic; local; response

(This special issue belongs to the Section Cancer Biology and Oncology)

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