Antibody Responses to Viral Infections: Insights from Structural Biology
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Microbiology in Human Health and Disease".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 19
Special Issue Editors
Interests: structural biology; antibody; virus; vaccine; immunity
2. Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD 20742, USA
Interests: X-ray crystallography; cryo-EM; antibody; epitope mapping
Special Issue Information
Dear Colleagues,
The structural elucidation of virus recognition and neutralization has transformed our understanding of viral immunity. This Special Issue will provide a comprehensive overview of the mechanisms underlying antibody-mediated viral neutralization and escape, providing cutting-edge insights from virology, immunology, and structural biology.
We cordially invite original research articles, reviews, and perspectives that explore high-resolution structures of virus–antibody complexes and provide structural insights into broadly neutralizing antibodies (bnAbs) across diverse viral families such as coronaviruses, influenza viruses, HIV, flaviviruses, and emerging zoonotic viruses. We especially welcome papers exploring structure-guided vaccine design and therapeutic antibody development informed by viral epitope mapping.
This Special Issue will foster a deeper understanding of how structural biology informs the development of effective vaccines, therapeutics, and diagnostic tools against viral diseases. Contributions from interdisciplinary teams combining structural analysis, immunological profiling, and virological studies are particularly encouraged.
Dr. Pragati Agnihotri
Dr. Sharanbasappa Karade
Guest Editors
Manuscript Submission Information
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Keywords
- crystal structure
- virus–antibody complexes
- broadly neutralizing antibodies
- immunology
- epitope mapping
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