Integrative Roles of Natural Products in Cancer Treatment and Chronic Inflammatory Disease
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".
Deadline for manuscript submissions: 30 April 2026 | Viewed by 117
Special Issue Editor
Interests: cancer; hyperthermia; heat shock response; ROS; natural product
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cancer is a multifactorial disease characterized by uncontrolled cell proliferation and the acquisition of metastatic potential. Natural products have attracted significant attention as promising anticancer agents due to their ability to selectively target malignant cells while minimizing toxicity in normal tissues. Furthermore, natural compounds can alleviate the side effects of conventional therapies such as chemotherapy, radiotherapy, and hyperthermia, thereby enhancing both treatment efficacy and patient tolerance.
Beyond oncology, natural products also demonstrate important therapeutic potential in chronic inflammatory diseases, including metabolic, cardiovascular, autoimmune, and neurodegenerative disorders. These conditions frequently coexist with cancer as comorbidities, posing additional challenges to clinical management. Natural products, through regulation of oxidative stress, inflammatory pathways, and metabolic mechanisms, offer opportunities for dual therapeutic models that combine anticancer activity with the modulation of comorbid chronic conditions.
This Special Issue could serve as a platform to highlight emerging research on the following:
- Molecular mechanisms of natural products in cancer therapy and chronic inflammatory diseases;
- Natural compounds with dual-function activity in enhancing anticancer efficacy while protecting or restoring tissue homeostasis;
- Therapeutic models addressing cancer with comorbid chronic conditions;
- Integrative and adjuvant strategies combining natural products with chemotherapy, radiotherapy, or hyperthermia;
- Mechanistic insights into natural product–mediated regulation of oxidative stress, immunity, and inflammation.
We kindly invite researchers to submit original research articles as well as review articles on these subject.
Dr. Seungho Baek
Guest Editor
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Keywords
- natural products
- cancer
- chronic inflammatory diseases
- therapy
- oxidative stress
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