Special Issues

Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Neurotransmitter Signaling in Central Nervous System Diseases: Mechanisms, Biomarkers and Therapeutic Targets
edited by
submission deadline 30 Oct 2026 | Viewed by 244 | Submission Open
Keywords: central nervous system; neurotransmitters; receptors; transporters; biomarker
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Musculoskeletal Diseases: From Molecular Basis to Therapy—3rd Edition submission deadline 31 Oct 2026 | 16 articles | Viewed by 32676 | Submission Open
Keywords: musculoskeletal diseases; bone cancer; soft tissue cancer; bone metastasis; natural compounds; anticancer drugs; osteoarthritis; joint tissues; biomarkers; inflammation; microRNAs; exosomes
(This special issue belongs to the Section Molecular and Translational Medicine)
Saving Lives from Myocardial Infarction: Prevention vs. Therapy
edited by Dong Wang
submission deadline 31 Oct 2026 | 5 articles | Viewed by 20230 | Submission Open
Keywords: myocardial infarction; molecular markers; AI-powered early detection; wearable devices; ischemia–reperfusion injury; artificial intelligence; ventricular remodeling; fibrosis control; molecular imaging; genomics; transcriptomics; proteomics; metabolomics; MI prevention
(This special issue belongs to the Section Molecular and Translational Medicine)
Medicinal Cannabis: Advances in Therapeutics and Clinical Applications
edited by
submission deadline 31 Oct 2026 | 2 articles | Viewed by 16887 | Submission Open
Keywords: medicinal cannabis; cannabidiol (CBD); cannabigerol (CBG); cannabinoid; cannabinol (CBN)
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Pathophysiology and Therapeutic Innovations in Skin and Appendage Disorders
edited by
submission deadline 31 Oct 2026 | 8 articles | Viewed by 15740 | Submission Open
Keywords: skin disorders; skin development; skin pathophysiology; tumorigenesis; psoriasis; atopic dermatitis; acne; innovative therapies; molecular dermatology; translational skin research
(This special issue belongs to the Section Cell Biology and Pathology)
Urticaria: New Insights into Pathogenesis, Diagnosis and Therapy
edited by
submission deadline 31 Oct 2026 | 4 articles | Viewed by 14130 | Submission Open
Keywords: acute urticaria; chronic urticaria; pathogenesis; mast cells; biomarkers; diagnosis; biologicals
(This special issue belongs to the Section Molecular and Translational Medicine)
State-of-the-Art Endocrine Cancer Biology and Oncology
edited by
submission deadline 31 Oct 2026 | 7 articles | Viewed by 12317 | Submission Open
Keywords: thyroid and parathyroid tumors; adrenal tumors (hormonally active and inactive, ACC); neuroendocrine tumors (NEN); pituitary neuroendocrine tumors (PiNETs)
(This special issue belongs to the Section Cancer Biology and Oncology)
Neurodegenerative Diseases: From Mechanisms to Therapeutic Approaches, 2nd Edition submission deadline 31 Oct 2026 | 5 articles | Viewed by 10386 | Submission Open
Keywords: neurodegenerative diseases; neurons; mechanism
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Navigating the Complex Landscape of Non-Communicable Respiratory Diseases: Emerging Challenges and Opportunities
edited by
submission deadline 31 Oct 2026 | 6 articles | Viewed by 9462 | Submission Open
Keywords: non-communicable respiratory diseases; asthma; idiopathic pulmonary fibrosis; chronic obstructive pulmonary disease
(This special issue belongs to the Section Molecular and Translational Medicine)
Molecular and Cellular Mechanisms of Cardiovascular Diseases: 2nd Edition
edited by
submission deadline 31 Oct 2026 | 5 articles | Viewed by 8832 | Submission Open
Keywords: hypertension; diabetes; coronary heart disease; valvular heart disease; infective endocarditis; aortic dissection; aortic aneurysm; heart failure; cardiomyopathy
(This special issue belongs to the Section Molecular and Translational Medicine)
Cannabinoids in Therapeutics: Mechanisms, Signaling Pathways and Personalized Treatment Strategies
edited by and
submission deadline 31 Oct 2026 | 6 articles | Viewed by 8144 | Submission Open
Keywords: cannabinoids; endocannabinoid system; cancer; pain; inflammation; personalized medicine; receptor signaling; therapeutic development; drug delivery; pharmacogenomics; systems pharmacology
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Innovations and Perspectives in Kidney Transplantation
edited by Vassilis Filiopoulos
submission deadline 31 Oct 2026 | 5 articles | Viewed by 8100 | Submission Open
Keywords: bioartificial kidney; immunology; immunosuppression; kidney transplantation; tolerance; graft rejection; graft survival; xenotransplantation; kidney regeneration
(This special issue belongs to the Section Immunology and Immunotherapy)
The Role of Ion Channels and Transporters in Human Health and Diseases (2nd Edition)
edited by Teresa Soda
submission deadline 31 Oct 2026 | 2 articles | Viewed by 7979 | Submission Open
Keywords: ion channels; transporters; ion pumps; voltage-gated channels; ionotropic receptors; TRP channels; store-operated channels; piezo channels; NALCN channels; inositol-1,4,5-receptors; ryanodine receptors; two-pore channels; synaptic transmission; channelopathies; neurodegenerative disorders; cardiovascular disorders
(This special issue belongs to the Section Molecular and Translational Medicine)
Type 2 Diabetes: Current Progress and Future Challenges
edited by
submission deadline 31 Oct 2026 | 5 articles | Viewed by 7942 | Submission Open
Keywords: type 2 diabetes; cardiovascular risk; novel antidiabetics; clinical guidelines therapeutic inertia; obesity; insulin resistance; metabolic syndrome; diabetology; family medicine
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Recent Advances in Adipokines (3nd Edition)
edited by
submission deadline 31 Oct 2026 | 9 articles | Viewed by 7847 | Submission Open
Keywords: adiponectin; receptor; agonist; biomarker; inflammation; cancer
(This special issue belongs to the Section Cell Biology and Pathology)
Kidney Diseases in Critical Ill Patients
edited by
submission deadline 31 Oct 2026 | 2 articles | Viewed by 7716 | Submission Open
Keywords: acute kidney disease; critical care; beside diagnostics; point of care ultrasounds; dialysis
(This special issue belongs to the Section Molecular and Translational Medicine)
Neuroimmunology and Neurological Infection
edited by
submission deadline 31 Oct 2026 | 3 articles | Viewed by 7174 | Submission Open
Keywords: neuroimmunology; neurological infections; immune-mediated diseases; neurodegeneration; biomarkers; immunotherapy; neuroinflammation; clinical neurology
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Biomarkers in Metabolic Disorders, Obesity and Type 2 Diabetes Mellitus—2nd Edition
edited by and Anna Maria Różańska-Walędziak
submission deadline 31 Oct 2026 | 5 articles | Viewed by 6889 | Submission Open
Keywords: metabolic disorders; obesity; type 2 diabetes mellitus; bariatric surgery; laboratory parameters
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Multidisciplinary Approaches to Neurodegenerative Disorders
edited by
submission deadline 31 Oct 2026 | 3 articles | Viewed by 6804 | Submission Open
Keywords: neurodegenerative disorders; lipid metabolism; comorbidity patterns super-agers; precision medicine; biomarker discovery; AI-assisted diagnostics; translational neuroscience; multi-omics integration; neuroinflammation
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Obesity-Related Gastrointestinal Disorders: Uncovering Mechanisms Behind Cardiometabolic Improvement with Weight Loss
edited by
submission deadline 31 Oct 2026 | 2 articles | Viewed by 6575 | Submission Open
Keywords: metabolic dysfunction-associated steatotic liver disease (MASLD); gastro-esophageal reflux disease (GERD); obesity; cardiometabolic comorbidities; type 2 diabetes; hypertension; gut hormones; gastrointestinal function
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Neurovascular Dysfunction: Mechanisms and Therapeutic Strategies
edited by
submission deadline 31 Oct 2026 | 3 articles | Viewed by 6069 | Submission Open
Keywords: neurovascular; blood vessels; nervous system; neurological diseases
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Emerging Technologies in Liquid Biopsy of Cancers
edited by Lingdi Yin
submission deadline 31 Oct 2026 | 2 articles | Viewed by 6025 | Submission Open
Keywords: liquid biopsy; circulating tumor cells (CTCs); circulating tumor DNA (ctDNA); exosomes; cancer diagnostics; biomarker discovery; minimally invasive monitoring; emerging technologies; clinical translation; molecular profiling
(This special issue belongs to the Section Cancer Biology and Oncology)
Human Stem Cells in Disease Modelling and Treatment (2nd Edition)
edited by Sofia M. Calado and
submission deadline 31 Oct 2026 | 5 articles | Viewed by 5801 | Submission Open
Keywords: induced pluripotent stem cells (iPSCs); embryonic stem cells (ESCs); disease models; cell therapies; cell therapy medicinal products (CTMPs); regenerative medicine
(This special issue belongs to the Section Biomedical Engineering and Materials)
Aortic Aneurysm: Mechanisms, Biomarkers, and Therapeutic Strategy submission deadline 31 Oct 2026 | 6 articles | Viewed by 5621 | Submission Open
Keywords: aortic aneurysms; genetic aortic diseases; endothelial dysfunction; extracellular matrix; aortic wall; aortic smooth muscle; angiotensin system; aortic wall elasticity; matrix metalloproteinases
(This special issue belongs to the Section Molecular and Translational Medicine)
New Insights into the Diagnosis and Treatment of Hepatocellular Carcinoma—2nd Edition
edited by
submission deadline 31 Oct 2026 | 1 articles | Viewed by 5523 | Submission Open
Keywords: checkpoint inhibitors; combinatorial treatments; hepatocellular carcinoma (HCC); immunotherapy; liver cancer; therapy; targeted therapy
(This special issue belongs to the Section Cancer Biology and Oncology)
Advances in Single-Cell and Spatial Transcriptomics: Decoding Tumor Heterogeneity and Microenvironment
edited by
submission deadline 31 Oct 2026 | 2 articles | Viewed by 5275 | Submission Open
Keywords: single-cell sequencing; spatial transcriptomics; tumor microenvironment; heterogeneity; immunotherapy resistance
(This special issue belongs to the Section Cancer Biology and Oncology)
Mycobacterial Infections: Insights into Pathogenesis, Diagnosis, and Treatment
edited by
submission deadline 31 Oct 2026 | 3 articles | Viewed by 5212 | Submission Open
Keywords: mycobacterium; pathogenesis; host–pathogen interactions; virulence factors; antimicrobial resistance; diagnosis; therapeutics; host-directed therapy; vaccine development; drug resistance
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Chronic Pain: From Prevention to Therapeutic Strategies—Third Edition
edited by Isaura Tavares and
submission deadline 31 Oct 2026 | 3 articles | Viewed by 5173 | Submission Open
Keywords: pain pathophysiology; pain prevention; predictive sensory testing; pre- and postoperative chronic pain; new biomarkers in pain; pain management and novel treatments; preemptive analgesia; inflammatory pain
(This special issue belongs to the Section Molecular and Translational Medicine)
Fertility and Reproductive Health: Understanding of Reproductive Physiology and Pathology
edited by Sevastiani Antonouli and
submission deadline 31 Oct 2026 | 1 articles | Viewed by 5135 | Submission Open
Keywords: female infertility; male infertility; oocyte quality; embryo implantation; follicular dynamics; gamete and embryo ultrastructure; assisted reproduction technologies; reproductive aging; fertility preservation; oncofertility challenges
(This special issue belongs to the Section Gene and Cell Therapy)
Multisystem Crosstalk in Health and Disease submission deadline 31 Oct 2026 | 1 articles | Viewed by 4582 | Submission Open
Keywords: systems biology; immunometabolism; inflammation; integrative physiology; molecular pathways; translational research; multi-omics; chronic disease; host–microbe interactions; metabolic regulation
(This special issue belongs to the Section Endocrinology and Metabolism Research)
New Trends in Regional Anesthesia and Pain Management
edited by
submission deadline 31 Oct 2026 | 3 articles | Viewed by 4468 | Submission Open
Keywords: regional anesthesia; ultrasound-guided/stimulator-guided nerve blocks; novel techniques for motor-sparing neural intervention; continuous catheter infusions; opioid-sparing techniques; perioperative pain management; novel local anesthetics; cadaveric dissection exploring the anatomical knowledge of motor-sparing techniques; modalities (techniques, technologies, or drug regimen) to prolong the effect of local anesthetics; ERAS-related studies; AI applications in regional anesthesia and pain management; innovations and protocols/curriculum regarding regional anesthesia and pain management in the battlefield; studies comparing new technologies/simulation (such as EpiFaith, SPRint PNS system, or CompuFlo) with traditional methods in improving regional anesthesia and pain management; regenerative medicine; nutritional pain medicine; application of bone marrow aspirate concentration or other stem cell components in pain medicine; multidisciplinary/comprehensive care program; transarterial embolization for pain management; joint denervation for pain management
(This special issue belongs to the Section Molecular and Translational Medicine)
Chronic Liver Disease: From Mechanisms to Therapeutic Approaches
edited by
submission deadline 31 Oct 2026 | 2 articles | Viewed by 4071 | Submission Open
Keywords: chronic liver disease; cirrhosis; portal hypertension; hepatocellular carcinoma; variceal bleeding; transjugular intrahepatic portosystemic shunt (TIPS)
(This special issue belongs to the Section Molecular and Translational Medicine)
Nervous System Injury and Repair: From Molecular Mechanism to Therapeutic Perspectives
edited by
submission deadline 31 Oct 2026 | 2 articles | Viewed by 3344 | Submission Open
Keywords: nervous system injury; neuron; astrocytes; microglial cells; excitotoxicity; inflammation; oxidative stress; neuroprotection
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Recent Advanced Research in Hypertension
edited by Rodrigo Maranon
submission deadline 31 Oct 2026 | 1 articles | Viewed by 3163 | Submission Open
Keywords: hypertension; sex differences; pathophysiology; precision medicine; novel therapeutics; digital health; cardiovascular disease
(This special issue belongs to the Section Cell Biology and Pathology)
Biomarker, Phenotyping and Therapeutics for Asthma
edited by
submission deadline 31 Oct 2026 | 4 articles | Viewed by 3158 | Submission Open
Keywords: allergy; biomarkers; pathogenesis; exhaled breath; multi-omics; lung physiology; phenotyping; endotypes; therapeutic targets
(This special issue belongs to the Section Molecular and Translational Medicine)
New Insights in Immunological Pathways
edited by
submission deadline 31 Oct 2026 | 2 articles | Viewed by 2741 | Submission Open
Keywords: immune response; immune signal pathway; cytokine storm
(This special issue belongs to the Section Immunology and Immunotherapy)
Progress in Cytotoxicity of Biomaterials
edited by Lakkamraju Vijayalakshmi
submission deadline 31 Oct 2026 | 1 articles | Viewed by 2735 | Submission Open
Keywords: biomaterial cytotoxicity; biocompatibility assessment; in vitro and in vivo toxicity; surface modification; nanomaterials in medicine; oxidative stress and inflammation; tissue engineering materials; drug delivery systems; biodegradable polymers; regulatory perspectives on biomaterial safety
(This special issue belongs to the Section Biomedical Engineering and Materials)
Oxidative Stress, Mitochondrial Dysfunction, and Aβ Pathology: Converging Pathways in Aging and Neurodegeneration
edited by , Laxmi Rathor and
submission deadline 31 Oct 2026 | 1 articles | Viewed by 2621 | Submission Open
Keywords: oxidative stress; aging; amyloid beta; tau phosphorylation; neurodegeneration; regulated cell death; mitochondrial biogenesis; Drosophila; C. elegans
(This special issue belongs to the Section Cell Biology and Pathology)
Phenotypes and Endotypes in Interstitial Lung Diseases—Second Edition
edited by
submission deadline 31 Oct 2026 | 2 articles | Viewed by 2599 | Submission Open
Keywords: interstitial lung diseases (ILDs); heterogeneity; pathogenesis; progressive pulmonary fibrosis (PPF); molecular biomarkers
(This special issue belongs to the Section Immunology and Immunotherapy)
Advances in Immunometabolism: Molecular Pathways, Regulatory Networks, and Therapeutic Opportunities submission deadline 31 Oct 2026 | 2 articles | Viewed by 2345 | Submission Open
Keywords: immunometabolism; metabolic reprogramming; immune-cell signaling; inflammation; tumor microenvironment; mitochondrial dysfunction; oxidative stress; immunometabolic checkpoints; biomarkers; targeted therapy
(This special issue belongs to the Section Immunology and Immunotherapy)
Immunotherapy and Immune-Related Adverse Events in Cancer submission deadline 31 Oct 2026 | 1 articles | Viewed by 2318 | Submission Open
Keywords: immunotherapy; cancer; PD-1 inhibitors; immune-related adverse effects; management
(This special issue belongs to the Section Immunology and Immunotherapy)
From Gut to Vascular Health: The Role of Probiotics, Polyphenols, and Diet in Neuroinflammation and Cardiovascular Dysfunction
edited by Maria Serra and
submission deadline 31 Oct 2026 | 1 articles | Viewed by 2292 | Submission Open
Keywords: nutrition supplements; plant extract; polyphenols; oxidative stress; inflammation; neuroinflammation; microbiota; cardiometabolic dysfunction
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Crosstalk Between Depression, Anxiety, Dementia, and Chronic Pain Comorbidity in Behavioral Neurology and Neuropsychiatry—4th Edition
edited by Masaru Tanaka and Simone Battaglia
submission deadline 31 Oct 2026 | 1 articles | Viewed by 2050 | Submission Open
Keywords: depression; anxiety; dementia; chronic pain; Alzheimer’s disease; Parkinson’s disease; multiple sclerosis; stroke; depressive disorder; anxiety disorder; schizophrenia; somatic symptom disorder; antidepressants; anxiolytics; nootropic agents; analgesics; neurodegeneration; neuroprotection; psychotherapy; serotonin; kynurenine
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Head and Neck Cancer: From Mechanisms to Therapeutic Approaches—Advances and Challenges submission deadline 31 Oct 2026 | 1 articles | Viewed by 1921 | Submission Open
Keywords: head and neck cancers; target therapy; biomarkers; molecular targets; translational research; pathogenesis; prognosis; diagnostic tool
(This special issue belongs to the Section Cancer Biology and Oncology)
Thoracic Malignancies: From Pathophysiology to Novel Therapeutic Approaches: 2nd Edition
edited by Yanyun Gao
submission deadline 31 Oct 2026 | 2 articles | Viewed by 1820 | Submission Open
Keywords: thoracic malignancies; lung cancer; esophageal cancer; pleural mesothelioma (PM); molecular subtypes; drug resistance; target therapy; biomarkers; immunotherapy; preclinical models
(This special issue belongs to the Section Cancer Biology and Oncology)
Molecular Psychiatry and Antipsychotics
edited by
submission deadline 31 Oct 2026 | 1 articles | Viewed by 1704 | Submission Open
Keywords: psychiatric diseases; schizophrenia; antipsychotics; molecular psychiatry; molecular pathways; neurotransmitter systems; positive, negative and cognitive symptoms
(This special issue belongs to the Section Molecular and Translational Medicine)
Small Molecules, from Natural Sources, in Drug Discovery
edited by and Cláudia Pinho
submission deadline 31 Oct 2026 | 2 articles | Viewed by 1685 | Submission Open
Keywords: natural products; translational research; drug discovery; herbal therapy; small molecules; therapeutic leads; pharmacology; natural bioactive compounds
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Advances in Lung Cancer: From Bench to Bedside (2nd Edition)
edited by
submission deadline 31 Oct 2026 | 2 articles | Viewed by 1478 | Submission Open
Keywords: lung cancer; immunotherapy; targeted therapy; translational oncology; biomarkers; EGFR; ALK; ROS1
(This special issue belongs to the Section Cancer Biology and Oncology)
Advances in Liver Fibrosis: From Mechanisms to Therapeutics
edited by
submission deadline 31 Oct 2026 | 1 articles | Viewed by 1394 | Submission Open
Keywords: liver fibrosis; therapeutic target; biomarker; hepatocyte; macrophage; LSEC; HSC; immune cells; extracellular matrix
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Molecular and Cellular Mechanisms in Metabolic Bone and Cartilage Disorders submission deadline 31 Oct 2026 | 2 articles | Viewed by 1388 | Submission Open
Keywords: metabolic bone; cartilage disorders; osteoporosis; osteoarthritis; impaired fracture healing; rare metabolic skeletal diseases
(This special issue belongs to the Section Endocrinology and Metabolism Research)
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