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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Nanoparticle-Based Drug Delivery in Cancer Therapy: Current Progress and Challenges

edited by

Menghuan Tang

and

Zhaoqing Cong

submission deadline 31 Jan 2026 | 3 articles | Viewed by 9670 | Submission Open

Keywords: nanoparticle; targeted drug delivery; controlled release; clinical translation; drug resistance; nanomedicine

(This special issue belongs to the Section Nanomedicine and Nanobiology)

New Advances in Human Reproductive Biology

edited by

Nikolaos Machairiotis

submission deadline 31 Jan 2026 | 6 articles | Viewed by 9634 | Submission Open

Keywords: gametogenesis; fertilization; egg retrieval; embryo implantation; epigenetics; microRNAs in fertility; hormonal signaling; stem cells and fertility; assisted reproductive technologies; molecular and polymorphism in fertility; reproductive health novelty

(This special issue belongs to the Section Molecular and Translational Medicine)

Applications and Perspectives of Cold Electric Discharge Plasmas in Biomedicine and Bioengineering

edited by

Andrei Vasile Nastuta

submission deadline 31 Jan 2026 | 6 articles | Viewed by 9350 | Submission Open

Keywords: plasma medicine; plasma pharmacology; plasma oncology; plasma bioengineering; plasma agronomy

(This special issue belongs to the Section Molecular and Translational Medicine)

Medicinal Chemistry in Drug Design and Discovery, 2nd Edition

edited by

Małgorzata Jarończyk

submission deadline 31 Jan 2026 | 4 articles | Viewed by 8664 | Submission Open

Keywords: design and synthesis of medicinal compounds; identification and characteristics of targets; mechanism of action; profiles of safety; structure– activity relationship; ligand– target interactions; drugs repurposing

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Parkinson’s Disease: Where Are We and Where Are We Going To

edited by Carmen Borrué

submission deadline 31 Jan 2026 | 1 articles | Viewed by 7652 | Submission Open

Keywords: Parkinson’ s disease; gait disorders; biomarkers; neurodegenerative disease; AI

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Feature Reviews in Infection and Immunity

edited by

Vijay Singh Gondil

submission deadline 31 Jan 2026 | 2 articles | Viewed by 7533 | Submission Open

Keywords: emerging pathogens; antimicrobial resistance; vaccine; host-pathogen immune interactions; immunotherapy; antimicrobial drug; immune evasion; innate and adaptive immunity

(This special issue belongs to the Section Immunology and Immunotherapy)

Advances in Cardiovascular Diseases: Pathophysiological Insights, Therapeutic Strategies and Future Directions

edited by

Azizah Ugusman

, Wan Amir Nizam Wan Ahmad and Dharmani Devi Murugan

submission deadline 31 Jan 2026 | 5 articles | Viewed by 7200 | Submission Open

Keywords: cardiovascular disease; pathophysiology; therapeutic strategies; translational research; complementary medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Role of Glycomics in Health and Diseases

edited by

Tijl Vermassen

submission deadline 31 Jan 2026 | 4 articles | Viewed by 7064 | Submission Open

Keywords: glycomics; protein chemistry; tumor immunology; biomarker research

(This special issue belongs to the Section Molecular and Translational Medicine)

Molecular Biomarkers and More Efficient Therapies for Sepsis—2nd Edition

edited by

Wen-Lin Su

, Chih-Hao Shen,

Sheng-Kang Chiu

and

Yi-Ting Chen

submission deadline 31 Jan 2026 | 4 articles | Viewed by 6407 | Submission Open

Keywords: sepsis; organ dysfunction; inflammatory process; molecular biomarkers; pathogen infection; signal transduction mechanisms

(This special issue belongs to the Section Molecular and Translational Medicine)

PPARs in Health and Disease, 2nd Edition

edited by

Maria Konstandi

submission deadline 31 Jan 2026 | 3 articles | Viewed by 6264 | Submission Open

Keywords: PPARα ; PPARβ /δ ; PPARγ ; nuclear receptor; lipid homeostasis; glucose homeostasis; neurodegenerative disorders; dyslipidemia; atherosclerosis; cardiovascular disease; cancer

(This special issue belongs to the Section Cell Biology and Pathology)

Cardiac and Vascular Diseases: Pathogenesis, Pharmacological Treatments, Advances in Therapies (3rd Edition)

edited by

Francesco Massari

and

Pietro Scicchitano

submission deadline 31 Jan 2026 | 6 articles | Viewed by 5783 | Submission Open

Keywords: endothelial function; cardiomyopathies; cardiovascular pharmacology; cardiac therapeutics; noninvasive vascular treatments; molecular cardiac biomarkers; molecular vascular biomarkers

(This special issue belongs to the Section Molecular and Translational Medicine)

Nephrotic Syndrome: Pathomechanism, Diagnostics and Novel Treatment Options—2nd Edition

edited by

Kan Katayama

submission deadline 31 Jan 2026 | 2 articles | Viewed by 5553 | Submission Open

Keywords: focal segmental glomerulosclerosis; genetic kidney disease; minimal change disease; nephrotic syndrome; podocyte

(This special issue belongs to the Section Molecular and Translational Medicine)

State-of-the-Art Neonatal Medicine in Japan

edited by

Fumihiko Namba

submission deadline 31 Jan 2026 | 3 articles | Viewed by 5539 | Submission Open

Keywords: mesenchymal stromal cells; artificial placenta; therapeutic gasses; animal models; off-label drug use

(This special issue belongs to the Section Molecular and Translational Medicine)

Advancements in Cardiac Imaging: Diagnostics, Prognostics, and Therapeutics

edited by Ilaria Dentamaro

submission deadline 31 Jan 2026 | 3 articles | Viewed by 5262 | Submission Open

Keywords: cardiac imaging; echocardiography; cardiovascular magnetic resonance imaging; cardio CT; nuclear cardiology

(This special issue belongs to the Section Molecular and Translational Medicine)

Gut Microbiota, Diet, and Immunity: Investigating the Connections and Implications for Disease Development—3rd Edition

edited by

Farhad Vahid

submission deadline 31 Jan 2026 | 4 articles | Viewed by 5252 | Submission Open

Keywords: gut microbiota; diet; immunity; microbiome; dysbiosis; inflammatory bowel diseases; cancer; CVD; T2D; obesity; overweight; autoimmune diseases; metabolic syndromes; immunomodulation; microbial diversity; nutrient– gut microbiota interactions; probiotics; prebiotics; immune system development; disease susceptibility; therapeutic interventions; host– microbe interactions; gut– brain axis; microbial metabolites; precision nutrition

(This special issue belongs to the Section Molecular and Translational Medicine)

Exosomes in Medicine: Recent Advances in Drug Delivery, Diagnostics, and Therapeutics

edited by Vetriselvan Subramaniyan

submission deadline 31 Jan 2026 | 3 articles | Viewed by 5098 | Submission Open

Keywords: exosomes; drug delivery; diagnostics; therapeutics; precision medicine; biomarkers; nanomedicine; inflammation and neurodegeneration; exosome engineering; translational research

(This special issue belongs to the Section Gene and Cell Therapy)

Ophthalmic Genetics: Unraveling the Genomics of Eye Disorders

edited by Raffaella Cascella

submission deadline 31 Jan 2026 | 4 articles | Viewed by 5057 | Submission Open

Keywords: ophthalmic genetics; inherited retinal disease; genomics; molecular biology; gene therapy; artificial intelligence; bioinformatics; biostatistical analysis

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Infectious Diseases: Prevention, Diagnosis, and Treatment Under Antimicrobial Resistance Global Urgency

edited by

Célia F. Rodrigues

submission deadline 31 Jan 2026 | 3 articles | Viewed by 4988 | Submission Open

Keywords: AMR; infectious diseases; bacteria; fungi; alternative treatment

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Molecular Mechanisms and Translational Research on Insulin Resistance

edited by

Terisha Ghazi

submission deadline 31 Jan 2026 | 2 articles | Viewed by 4680 | Submission Open

Keywords: insulin resistance; type 2 diabetes mellitus; metabolic syndrome; insulin signaling; inflammation; oxidative stress; mitochondrial dysfunction; epigenetics; epitranscriptomics (e.g.; m6A RNA methylation); biomarkers; translational medicine; therapeutic targets

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Advances in Genetic Research and Molecular Diagnostics for Hematological Diseases

edited by Ying S. Zou and Leonard N. Yenwongfai

submission deadline 31 Jan 2026 | 3 articles | Viewed by 4578 | Submission Open

Keywords: hematological diseases; genetic research; benign hematology; inherited disorders; next-generation sequencing/long-read sequencing; optical genome mapping; transcriptome; proteomics; digital pathology; deep convolutional neural networks

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Exploring Potential Therapeutic Compounds with Anti-Inflammatory Activity

edited by Shomaila Mehmood

submission deadline 31 Jan 2026 | 2 articles | Viewed by 4417 | Submission Open

Keywords: green tea polyphenols; isoflavanoids; resveratrol; curcumin; genistein; melatonin; antioxidants; metalloporphyrins; anti-inflammatory compounds

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Combination Therapy for Chronic Diseases: Bridging Conventional and Natural Products for Enhanced Outcomes

edited by

Xian (Phoebe) Zhou

submission deadline 31 Jan 2026 | 2 articles | Viewed by 4344 | Submission Open

Keywords: combination therapy; interaction; chronic diseases; synergy; molecular pathways; mathematical methods; minimizing side effects

(This special issue belongs to the Section Molecular and Translational Medicine)

Brain Injury: New Insights into Mechanisms and Future Promising Treatments—Second Edition

edited by

Kristina Pilipović

and

Petra Dolenec

submission deadline 31 Jan 2026 | 3 articles | Viewed by 4264 | Submission Open

Keywords: acquired brain injury; nanomedicine; nanotechnology; neuroregenerative therapy; neurorepair; new and emerging treatments; pharmacotherapy; stroke; tissue engineering; traumatic brain injury

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Pathogenesis, Diagnostics and Therapeutics in Obsterics and Gynaecology (2nd Edition)

edited by

Nikolaos Machairiotis

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3716 | Submission Open

Keywords: gynaecology; obstetrics; diagnosis; pathogenesis; treatment

(This special issue belongs to the Section Molecular and Translational Medicine)

Recent Advances in Targeted Drug Delivery Systems

edited by

Santosh Bashyal

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3659 | Submission Open

Keywords: targeted drug delivery systems; nanocarriers (lipid or polymeric); stimuli-responsive carriers; exosomes or exosome-mimetic vesicles; disease targeting; tumor targeting; theranostics

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

The Molecular Basis of the Immune Response in Pulmonary Fibrosis

edited by

Tamara Cruz

and

Fernanda Hernandez

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3175 | Submission Open

Keywords: immune response; fibrosis; aging; senescence

(This special issue belongs to the Section Immunology and Immunotherapy)

Autonomic Disorders: From Mechanisms to Therapeutic Approaches

edited by Svetlana Blitshteyn

submission deadline 31 Jan 2026 | 1 articles | Viewed by 3067 | Submission Open

Keywords: autonomic disorders; autonomic dysfunction; dysautonomia; orthostatic intolerance; therapeutics

(This special issue belongs to the Section Molecular and Translational Medicine)

Neurovascular Dysfunction: Mechanisms and Therapeutic Strategies

edited by

Deepti Diwan

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2744 | Submission Open

Keywords: neurovascular; blood vessels; nervous system; neurological diseases

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Neural Nexus: Interdisciplinary Perspectives on Neurological Disorders

edited by Gianandrea Traversi,

Marianna Mazza

and Giuseppe Marano

submission deadline 31 Jan 2026 | 1 articles | Viewed by 2546 | Submission Open

Keywords: neurological disorders; mental health; artificial intelligence; machine learning; biomarkers; drug discovery; therapeutic targets; neuroscience research

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Advances in Therapeutic Strategies in Gynecological Malignant Tumors—2nd Edition

edited by

Alberto Farolfi

submission deadline 31 Jan 2026 | 1 articles | Viewed by 2273 | Submission Open

Keywords: targeted therapy; precision medicine; gynecological cancers; ovarian cancer; endometrial cancer; cervical cancer

(This special issue belongs to the Section Cancer Biology and Oncology)

Biomarkers in Metabolic Disorders, Obesity and Type 2 Diabetes Mellitus—2nd Edition

edited by

Maciej Walędziak

and Anna Maria Różańska-Walędziak

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1964 | Submission Open

Keywords: metabolic disorders; obesity; type 2 diabetes mellitus; bariatric surgery; laboratory parameters

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Clinical, Radiological, and Molecular Insights into Craniopharyngioma

edited by Ernest Jan Bobeff and

Bartosz Szmyd

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1903 | Submission Open

Keywords: neuro-oncology; brain tumors; skull base; craniopharyngioma; stalk

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Feature Reviews in Ophthalmology

edited by

Ana Maria Dascalu

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1878 | Submission Open

Keywords: glaucoma; retinal diseases; diabetic retinopathy; age-related macular degeneration; retinitis pigmentosa; Leber's congenital amaurosis; ocular surface pathology

(This special issue belongs to the Section Molecular and Translational Medicine)

Applications and Developments of Metal-Based Drugs

edited by

Sajal Sen

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1804 | Submission Open

Keywords: anticancer; anti-infectious diseases; nuclear medicines; immunotherapeutic; drug delivery; organometallic complexes; metal-based drugs; metallotherapeutic drugs

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

New Advances in Insulin—100 Years Since Its Discovery: 2nd Edition

edited by

Tomislav Bulum

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1674 | Submission Open

Keywords: insulin action; insulin analogs; type 1 diabetes; type 2 diabetes; complications; glucose homeostasis

(This special issue belongs to the Section Cell Biology and Pathology)

New Advances in Chronic Kidney Disease: Biology, Diagnosis and Therapy (3rd Edition)

edited by

Susana Coimbra

and

Alice Santos-Silva

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1424 | Submission Open

Keywords: inflammation; kidney biomarkers; kidney injury; chronic kidney disease; dialysis; cardiorenal syndrome risk; CKD anemia; kidney physiopathology; CKD treatment

(This special issue belongs to the Section Cell Biology and Pathology)

Glaucoma: New Diagnostic and Therapeutic Approaches, 3rd Edition

edited by

Da-Wen Lu

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1298 | Submission Open

Keywords: glaucoma; ocular pharmacology; ocular disease

(This special issue belongs to the Section Molecular and Translational Medicine)

Molecular Research and Recent Advances in Diabetic Retinopathy—3rd Edition

edited by

Tomislav Bulum

and

Martina Tomić

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1248 | Submission Open

Keywords: diabetes; diabetic retinopathy; complications; vascular endothelial growth factor; retina; biomarkers

(This special issue belongs to the Section Molecular and Translational Medicine)

Emerging Technologies in the Diagnosis and Management of Neurological Disorders

edited by

Luca Filippi

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1170 | Submission Open

Keywords: neurological disorders; advanced diagnostic imaging modalities; neurophysiological tools

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Genetically Determined Cardiovascular Disease

edited by

Gaetano Thiene

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1150 | Submission Open

Keywords: genetically determined cardiovascular diseases; genetic mutations; oligogenic inheritance; congenital heart defects; atherosclerosis

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Atrial Fibrillation: From Pathogenesis to Treatment Strategies

edited by

Dimitrios A. Vrachatis

, Theodore G. Papaioannou and

Ioannis Anagnostopoulos

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1058 | Submission Open

Keywords: atrial fibrillation; arrhythmia; ablation; PFA; radiofrequency; cryoablation; pathophysiology; pathophysiology; molecular mechanisms

(This special issue belongs to the Section Molecular and Translational Medicine)

The Renin–Angiotensin System in Immune Regulation: Roles in Blood, Vessels, and Inflammation

edited by Chao Liu

submission deadline 31 Jan 2026 | 1 articles | Viewed by 941 | Submission Open

Keywords: renin– angiotensin system; immune regulation; vascular biology; inflammation; T cells; macrophages; neutrophils; angiotensin II; ACE2; stem cells

(This special issue belongs to the Section Immunology and Immunotherapy)

Pharmacological Mechanisms and Target Discovery in Lung Injury-Driven Fibrosis: From Molecular Pathways to Preclinical Innovation

edited by

Huifang Tang

submission deadline 31 Jan 2026 | 1 articles | Viewed by 766 | Submission Open

Keywords: lung injury and fibrosis; pharmacological mechanisms; target discovery; mechanistic drivers; target identification; drug design; preclinical models

(This special issue belongs to the Section Molecular and Translational Medicine)

Advancements and Challenges in Anticancer Targeted Therapy with Small Molecules

edited by Monika Papiez

submission deadline 31 Jan 2026 | 1 articles | Viewed by 766 | Submission Open

Keywords: small molecules; cancer; anticancer targeted therapy; cancer resistance; cancer growth blockers

(This special issue belongs to the Section Cancer Biology and Oncology)

New Advances in Biomaterials for Tissue Repair and Regeneration

edited by Fei Xing, Wen Nie and Zhao Chen

submission deadline 31 Jan 2026 | 1 articles | Viewed by 658 | Submission Open

Keywords: biomaterials; nanomaterials; tissue repair; 3D printing; functionals biomaterials; biomaterial science; tissue regeneration

(This special issue belongs to the Section Biomedical Engineering and Materials)

Cancer Pharmacology

edited by Zhi Shi

submission deadline 31 Jan 2026 | 1 articles | Viewed by 512 | Submission Open

Keywords: cancer pharmacology; anticancer drug; cancer chemotherapy; targeted therapy; cancer immunotherapy; combination therapy; drug resistance

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Urothelial Carcinoma: Role of Biomarkers in Diagnosis, Prognosis and Treatment (2nd Edition)

edited by Ioannis Zachos and

Panagiotis Vlachostergios

submission deadline 31 Jan 2026 | 1 articles | Viewed by 456 | Submission Open

Keywords: urothelial carcinoma; biomarker; diagnosis; treatment; prognosis

(This special issue belongs to the Section Molecular and Translational Medicine)

Extracellular Vesicles: Research Advances in Cancer Treatment and Diagnostics

edited by

Luís R. Raposo

submission deadline 31 Jan 2026 | Viewed by 368 | Submission Open

Keywords: extracellular vesicles; exosomes; cancer therapy; diagnostics; cellular communication; tumor microenvironment; EV biogenesis

(This special issue belongs to the Section Cancer Biology and Oncology)

Emerging Research in Neurorehabilitation, 2nd Edition

edited by

Manuel Gaviria

submission deadline 31 Jan 2026 | Viewed by 353 | Submission Open

Keywords: mechanisms; CNS trauma; ischemic CNS injury; neurodegenerative disorders; neurorehabilitation; neuroplasticity; personalized therapy; neuroprosthetics; brain– computer interfaces; neurodevelopmental disorder

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

New Advances in Epilepsy Research

edited by Duyu A. Nie

submission deadline 31 Jan 2026 | Viewed by 349 | Submission Open

Keywords: disease mechanisms; genetics; biomarkers; epilepsy surgery; electroencephalogram; animal models; artificial intelligence

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

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