Special Issues

Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Bioavailability, Metabolism, and Health Effects of Phenolic Compounds
edited by and Alice Cattivelli
submission deadline 28 Feb 2026 | 3 articles | Viewed by 7735 | Submission Open
Keywords: phenolic compounds; gut microbiota; metabolism; cardiovascular diseases; cancer; anti-proliferative activity; bioavailability; bioaccessibility
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Young Researchers in Ecology submission deadline 28 Feb 2026 | 5 articles | Viewed by 7568 | Submission Open
Keywords: adaptations to variable environments; biodiversity; biogeography; biotic interactions (e.g.; competition; predation parasitism; mutualism; amensalism; commensalism); community assembly; conservation; ecological management and restoration; ecological sustainability; ecosystem processes (productivity; decomposition; nutrient cycling); evolution; functional traits; global changes (e.g.; climate change; land use change; biological invasions; nitrogen deposition); landscape ecology; life histories; physiological ecology; population dynamics; protected areas; succession; trophic levels         TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //     This page is in English   Translate to Simplified Chinese         Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh   Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com
(This special issue belongs to the Section Ecology)
Nutraceutical and Bioactive Compounds in Foods
edited by and
submission deadline 28 Feb 2026 | 3 articles | Viewed by 6373 | Submission Open
Keywords: bioactive compounds; functional food ingredients; nutraceuticals; antioxidant and anti-inflammatory agents; metabolic regulation; biotechnology in food science; gut microbiota interactions   This page is in English   Translate to Simplified Chinese         Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh   Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com
(This special issue belongs to the Section Biotechnology)
Nature's Pharmacy: Ethnobotanical Approaches to Medicinal Plant Research for the Discovery and Development of Potential Phytochemicals submission deadline 28 Feb 2026 | 5 articles | Viewed by 6293 | Submission Open
Keywords: medicinal plants; herbal medicine; ethnopharmacology; drug discovery; bioactive compounds; biological activity; molecular mechanism; signaling pathway
(This special issue belongs to the Section Plant Science)
RNA Biology and Roles in Diseases
edited by Nan Wu and
submission deadline 28 Feb 2026 | 2 articles | Viewed by 4585 | Submission Open
Keywords: RNA biology; diseases; circRNA; mRNA; non-coding RNA
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Molecular Basis of Metabolic Homeostasis
edited by Verónica Miksztowicz
submission deadline 28 Feb 2026 | 2 articles | Viewed by 2993 | Submission Open
Keywords: metabolic homeostasis; adipose tissue; liver diseases; cardiovascular disease TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //
(This special issue belongs to the Section Cell Biology)
Animal Models of Autoimmune Diseases
edited by Feng Zhu and Keqiang Chen
submission deadline 28 Feb 2026 | 1 articles | Viewed by 2515 | Submission Open
Keywords: autoimmune disease; infection; innate immunity; inflammation; cancer risk; therapeutic target; adaptive immunity
(This special issue belongs to the Section Physiology)
Hope for the Forgotten: Tackling Endemic Parasitic Diseases with New Tools and Ideas
edited by Cecilia Perez Brandán
submission deadline 28 Feb 2026 | 3 articles | Viewed by 1583 | Submission Open
Keywords: parasitic diseases; neglected tropical diseases (NTDs); host– parasite interactions; virulence mechanisms; immune evasion; molecular pathogenesis; genomic adaptations; drug discovery; drug repurposing; vaccine development; diagnostic biomarkers; tropical medicine; endemic infections
(This special issue belongs to the Section Infection Biology)
The Role of Gut Microbiota in Human Metabolism and Disease submission deadline 28 Feb 2026 | 1 articles | Viewed by 725 | Submission Open
Keywords: microbiota; bacteriome; fungiome; virome; cross-talk
Advancements in Mesenchymal Stem Cell-Derived Secretome
edited by Chiara Giannasi
submission deadline 28 Feb 2026 | Viewed by 370 | Submission Open
Keywords: mesenchymal stem cells; secretome; extracellular vesicles; conditioned medium; cell-free therapeutics; regeneration; immunomodulation; inflammation
(This special issue belongs to the Section Cell Biology)
Regulatory Mechanisms of Gene Expression and Its Regulatory Networks
edited by , and Ionara Rodrigues Siqueira
submission deadline 28 Feb 2026 | Viewed by 239 | Submission Open
Keywords: transcriptional regulation; gene regulatory networks; epigenetic mechanisms; non-coding RNAs; functional genomics; multi-omics integration; signaling pathways; systems biology; epidrugs; pharmaco-transcriptomics
(This special issue belongs to the Section Genetics and Genomics)
Diabetes and Cardiovascular Diseases in the New Era
edited by Prashilla Soma and
submission deadline 28 Feb 2026 | Viewed by 235 | Submission Open
Keywords: metabolic dysregulation; endothelial dysfunction; inflammation; immune response; molecular signaling pathways; oxidative stress and vascular remodeling
(This special issue belongs to the Section Medical Biology)
Photomorphogenesis and Stress Response Mechanisms Involving Light in Plants
edited by Ilektra Sperdouli
submission deadline 28 Feb 2026 | Viewed by 204 | Submission Open
Keywords: light quality and quantity; photoprotection; photoinhibition; chlorophyll; photoreceptors; abiotic stress; antioxidant defense; hormonal interactions; growth responses
(This special issue belongs to the Section Plant Science)
Uncovering the Intricate Relationship Between the Human Microbiome and Chronic Diseases
edited by
submission deadline 28 Feb 2026 | Viewed by 195 | Submission Open
Keywords: gut microbiome; oral microbiome; metabolomics; proteomics; inflammation; multi-omics; diet; cardiovascular diseases; type 2 diabetes mellitus
(This special issue belongs to the Section Medical Biology)
Algal Stress Responses: Molecular and Ecological Perspectives
edited by
submission deadline 28 Feb 2026 | Viewed by 190 | Submission Open
Keywords: phytoplankton; stress; global changes
(This special issue belongs to the Section Ecology)
Effects of Ionizing Radiation on Biomolecular Systems
edited by Antonella Bertucci
submission deadline 28 Feb 2026 | Viewed by 125 | Submission Open
Keywords: biomarkers; ionizing radiation; omics; high-throughput; dose
(This special issue belongs to the Section Biophysics)
Transcription Factors and Signaling Pathways in Tooth and Craniofacial Development
edited by Devi Atukorallaya
submission deadline 28 Feb 2026 | Viewed by 111 | Submission Open
Keywords: teeth; taste buds; facial bones and cartilage; animal models; birth defects; dental hard tissue development and mineralization; regeneration; cell signaling pathways
(This special issue belongs to the Section Biochemistry and Molecular Biology)
The Biology, Ecology, and Management of Plant Pests
edited by , , Suli Liu and Yuxin Zhou
submission deadline 1 Mar 2026 | 6 articles | Viewed by 4407 | Submission Open
Keywords: climate change; genetic diversity; life table; population dynamic; biomathematics; insect behavior; insect physiology; pest resistance; molecular mechanism; olfactory peripheral neurons; insecticide resistance; plant– pest– natural enemy; plant– insect-vector– pathogen; integrated pest management; pest monitoring and early warning
(This special issue belongs to the Section Ecology)
Physiological and Pathophysiological Responses to Biomaterials 2.0: From Nano- to Microscale Effects and Interactions submission deadline 31 Mar 2026 | 4 articles | Viewed by 11989 | Submission Open
Keywords: extracellular stimuli and physiological responses; plasma membrane interface; cell– material interactions; tissue– material interactions; tissue engineering; biomaterials; biomedical devices; in vitro models and on-chip/microfluidic systems; bioreactors; structure– function relationship
(This special issue belongs to the Section Physiology)
Proteomics and Human Diseases
edited by Lei Fang
submission deadline 31 Mar 2026 | 4 articles | Viewed by 9070 | Submission Open
Keywords: proteomics; clinical proteomics; human diseases; biomarker identification; therapeutic target; molecular mechanism; cancers; metabolic diseases; cardiovascular diseases; neurodegeneration diseases
(This special issue belongs to the Section Medical Biology)
The Emerging Role of Mitochondria in Neurobiology submission deadline 31 Mar 2026 | 1 articles | Viewed by 5027 | Submission Open
Keywords: mitochondrial dynamics; neurodegenerative diseases; neuronal bioenergetics; synaptic function; neurogenesis; neuronal plasticity
(This special issue belongs to the Section Neuroscience)
How Epigenetics Shapes the Nervous System
edited by
submission deadline 31 Mar 2026 | 3 articles | Viewed by 4968 | Submission Open
Keywords: nervous system; epigenetics; DNA methylation; histone tail modifications; non-coding RNAs; neurological disorders; neurodegenerative diseases; biomarkers; environmental epigenetics
(This special issue belongs to the Section Neuroscience)
Feeding Biology and Nutrition in Insects
edited by and Christopher W. Weldon
submission deadline 31 Mar 2026 | 3 articles | Viewed by 4855 | Submission Open
Keywords: diet; digestion; ecology; evolution; feeding; insects; mass-rearing; microbiome; nutrients; taste
(This special issue belongs to the Section Ecology)
Advances in Biological Research of Chiroptera
edited by Jiang Feng, Ying Liu and
submission deadline 31 Mar 2026 | 6 articles | Viewed by 4175 | Submission Open
Keywords: individual development; ecolocation; powered flight; high-frequency hearing; pest control; bat ecosystem service; habitat suitability; evolutionary adaptations
(This special issue belongs to the Section Zoology)
Pathophysiology of Testis
edited by María Susana Theas, and María Noel Galardo
submission deadline 31 Mar 2026 | 2 articles | Viewed by 3764 | Submission Open
Keywords: testis; infertility; aging; inflammation; spermatogenesis; steroidogenesis; energy balance
(This special issue belongs to the Section Physiology)
Microbial Life at the Extremes: From Environmental Diversity to Functional Insights submission deadline 31 Mar 2026 | 3 articles | Viewed by 3039 | Submission Open
Keywords: extremophiles; microbial diversity; functional adaptation; extreme environment; synthetic extreme environments; biosignatures TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //     This page is in English   Translate to Simplified Chinese         Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh   Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com
(This special issue belongs to the Section Ecology)
Animal Models of Gastrointestinal Diseases
edited by Yan Hu
submission deadline 31 Mar 2026 | 2 articles | Viewed by 2444 | Submission Open
Keywords: gastrointestinal diseases; animal models; digestive system; inflammatory bowel diseases; colorectal cancer; disease pathology; research methodologies; therapeutic interventions; clinical applications; translational research
(This special issue belongs to the Section Physiology)
Gene–Environment Interactions in Evolutionary Developmental Biology
edited by Alexander Shingleton
submission deadline 31 Mar 2026 | 1 articles | Viewed by 2402 | Submission Open
Keywords: phenotypic plasticity; gene– environment interactions; genetic architecture of plasticity; mechanisms of phenotypic variation; anthropogenic stressors; evolution of plastic responses
(This special issue belongs to the Section Evolutionary Biology)
Biological Control and Molecular Biology of Bacterial Plant Diseases
edited by Lei Li and Xiaofeng Zhou
submission deadline 31 Mar 2026 | 1 articles | Viewed by 2022 | Submission Open
Keywords: bacterial plant diseases; biological control; plant pathogens; endophytes; genomic; transcriptomic; and proteomic studies of antagonistic or pathogenic bacteria interactions; pathogenic mechanism
(This special issue belongs to the Section Plant Science)
Gene Editing and Genetic Regulation: New Insight in Insect Sex Determination, Reproductive Development and Pest Control
edited by Honglun Bi
submission deadline 31 Mar 2026 | 1 articles | Viewed by 1984 | Submission Open
Keywords: insect gene editing; genetic regulation  ; CRISPR/Cas  ; gene drive  ; pest control; sex determination  ; reproductive development; insect sterile technique
(This special issue belongs to the Section Zoology)
Exploring the Biodiversity, Taxonomy, Ecology and Genomics of Fungi submission deadline 31 Mar 2026 | 1 articles | Viewed by 1844 | Submission Open
Keywords: biodiversity; ecological roles of fungi; fungal communities; genomics; polyphasic approaches; metabolomics
In Vitro 2.0—Improving the Cell Culture Environment for Biology
edited by
submission deadline 31 Mar 2026 | 2 articles | Viewed by 1831 | Submission Open
Keywords: in vitro technologies; microfluids; bioreactors; organoids; tissue engineering; lab-on-a-chip; life-support systems; symbioses
(This special issue belongs to the Section Cell Biology)
Aquatic Animal Pathogens and Immunity
edited by and Junsoung Kwak
submission deadline 31 Mar 2026 | 1 articles | Viewed by 1818 | Submission Open
Keywords: disease mechanism; diagnosis methods for emerging diseases; host– pathogen interaction; immune defense mechanism; vaccines; immunostimulants; disease control and prevention; therapy
(This special issue belongs to the Section Microbiology)
Cardiovascular Autonomic Function: From Bench to Bedside—2nd Edition
edited by and
submission deadline 31 Mar 2026 | 2 articles | Viewed by 1392 | Submission Open
Keywords: dysautonomia; heart rate variability; autonomic function testing; cardiovascular autonomic function; autonomic neuroscience; syncope; orthostatic hypotension; baroreflex; autonomic molecular mechanisms
Biodiversity, Conservation, and Application of Crustaceans
edited by and Alejandro M. Maeda-Martinez
submission deadline 31 Mar 2026 | 2 articles | Viewed by 1327 | Submission Open
Keywords: application; aquaculture; aquatic ecology; biodiversity and conservation; crustaceans; evolutionary biology; experimental toxicology; genetic diversity; phylogenetic relationships; taxonomy and classification
(This special issue belongs to the Section Conservation Biology and Biodiversity)
Decoding the Molecular Landscape of Atopic Dermatitis: Bridging Mechanisms, Biomarkers, and Therapeutics
edited by and
submission deadline 31 Mar 2026 | Viewed by 291 | Submission Open
Keywords: atopic dermatitis; molecular pathogenesis; immune dysregulation; epidermal barrier dysfunction; skin microbiome; cytokine signaling; JAK-STAT pathway; therapeutic biomarkers; precision dermatology; neuroimmune interactions
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Latest Biological Advances in Neuromuscular Diseases
edited by James P. Orengo
submission deadline 31 Mar 2026 | Viewed by 242 | Submission Open
Keywords: neuromuscular medicine; muscle disease; neuropathy; neurogenetics; neurological disorders; neurodegeneration; neurology
(This special issue belongs to the Section Neuroscience)
Molecular Insights into the Immune Contexture of Tumors
edited by and Guilherme Zweig Rocha
submission deadline 31 Mar 2026 | Viewed by 174 | Submission Open
Keywords: immunology; immune oncology; cancer; molecular biology; biomarkers; inflammation
(This special issue belongs to the Section Cancer Biology)
Advances in the Molecular Evolution of Free-Living and Plant Parasitic Nematodes
edited by
submission deadline 31 Mar 2026 | Viewed by 160 | Submission Open
Keywords: biodiversity; biogeography; criptic species; phylogenetics; sequencing
(This special issue belongs to the Section Zoology)
Signaling Mechanisms Controlling Cell Fate in Cancer
edited by Wittaya Chaiwangyen and
submission deadline 31 Mar 2026 | Viewed by 121 | Submission Open
Keywords: cell fate; cancer signaling; miRNA; p53; Wnt; apoptosis; proliferation; differentiation; therapy resistance; biomarkers
(This special issue belongs to the Section Cell Biology)
Bird Biology and Conservation submission deadline 15 Apr 2026 | 12 articles | Viewed by 18944 | Submission Open
Keywords: avian conservation; ecological modeling; GIS; spatial ecology; telemetry
(This special issue belongs to the Section Conservation Biology and Biodiversity)
Mitochondria: The Signaling Organelle
edited by
submission deadline 15 Apr 2026 | 3 articles | Viewed by 7010 | Submission Open
Keywords: mitochondria; signal transduction; homeostasis; metabolism; apoptosis; redox biology; organelle communication
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Microbial Drivers of Aquatic Ecosystem Function: From Genomes to Biogeochemical Cycles
edited by and Jinjun Kan
submission deadline 15 Apr 2026 | 1 articles | Viewed by 321 | Submission Open
Keywords: aquatic microbial ecology; harmful algal blooms; nutrient cycling; trophic interactions; omics technologies; ecosystem resilience; bioremediation; population dynamics in aquatic ecosystems
(This special issue belongs to the Section Marine and Freshwater Biology)
Maternal Adaptation in Physiological and Pathological Pregnancy (2nd Edition)
edited by and
submission deadline 15 Apr 2026 | Viewed by 192 | Submission Open
Keywords: pregnancy; maternal adaptation; placenta; cardiovascular system; immune system; complications of preg-nancy; early prediction
(This special issue belongs to the Section Developmental and Reproductive Biology)
Biology, Ecology, Management and Conservation of Canidae
edited by Alberto Meriggi and
submission deadline 30 Apr 2026 | 8 articles | Viewed by 20142 | Submission Open
Keywords: Canidae; biology; ecology; management; conservation; ecosystem; habitats; niches; biodiversity; physiology; reproduction
(This special issue belongs to the Section Conservation Biology and Biodiversity)
Zoonotic Diseases submission deadline 30 Apr 2026 | 7 articles | Viewed by 8895 | Submission Open
Keywords: zoonoses; zoonotic agents; bacteria; viruses; fungi; protozoa; helminths
(This special issue belongs to the Section Infection Biology)
Application of Metabolomics and Integrated Computing in Chemical Biology
edited by
submission deadline 30 Apr 2026 | 3 articles | Viewed by 5924 | Submission Open
Keywords: chemical biology; computational biology; metabolomics; computational modeling; new chemical entities (NCE); active pharmaceutical ingredients (API); characterization; metabolite profiling
Machine Learning Applications in Biology—2nd Edition submission deadline 30 Apr 2026 | 4 articles | Viewed by 5542 | Submission Open
Keywords: machine learning; genomics; epigenomics; genetic variation and the environment; gene regulatory networks; integration of multipurpose NGS data
(This special issue belongs to the Section Bioinformatics)
Advances in Systems Metabolic Engineering for Biochemicals Production
edited by
submission deadline 30 Apr 2026 | 3 articles | Viewed by 4503 | Submission Open
Keywords: systems metabolic engineering; biochemicals; synthetic biology; bioprocess engineering; pathway modification; strain development
(This special issue belongs to the Section Microbiology)
Advancing Translational Science Using Bioinformatics and Big Data-Driven Approaches
edited by
submission deadline 30 Apr 2026 | 4 articles | Viewed by 4036 | Submission Open
Keywords: bioinformatics; big data analytics; artificial intelligence (AI); machine learning; deep learning; translational science; computational biology; drug repositioning; biomarker discovery; genomics; medical imaging; digital pathology; integrative analysis; disease mechanisms; functional genomics analysis; computational tool application; ethical and safety considerations; data-driven approaches
(This special issue belongs to the Section Bioinformatics)
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